Critical Reviews in Biotechnology,
Год журнала:
2023,
Номер
44(2), С. 319 - 336
Опубликована: Янв. 2, 2023
Phloroglucinol
and
derived
compounds
comprise
a
huge
class
of
secondary
metabolites
widely
distributed
in
plants
brown
algae.
A
vast
array
biological
activities,
including
antioxidant,
anti-inflammatory,
antimicrobial,
anticancer
has
been
associated
to
this
compounds.
In
review,
the
available
data
on
antiviral
antibacterial
capacity
phloroglucinols
have
analyzed.
Some
these
derivatives
show
important
antimicrobial
properties
vitro.
Phloroglucinols
shown
be
effective
against
viruses,
such
as
human
immunodeficiency
virus
(HIV),
herpes
or
enterovirus,
preliminary
through
docking
analysis
suggest
that
they
can
SARS-CoV-19.
Also,
some
effects
diverse
bacteria
strains,
Bacillus
subtilis
Staphylococcus
aureus,
(semi)synthetic
development
novel
led
with
significantly
increased
activity.
However,
therapeutic
use
is
hindered
by
absence
vivo
studies
scarcity
information
their
mechanisms
action,
hence
further
research
efforts
are
required.
On
basis
consideration,
our
work
aims
gather
regarding
efficacy
natural-occurring
synthetic
phloroglucinol
agents
pathogens,
which
published
during
last
three
decades.
The
recollection
results
reported
review
represents
valuable
source
updated
will
potentially
help
researchers
agents.
Communications Biology,
Год журнала:
2025,
Номер
8(1)
Опубликована: Янв. 6, 2025
Over
the
past
decades,
human
impacts
have
changed
structure
of
tropical
benthic
reef
communities
towards
coral
depletion
and
macroalgal
proliferation.
However,
how
these
changes
modified
chemical
microbial
waterscapes
is
poorly
known.
Here,
we
assessed
experimental
removal
assemblages
influences
composition
two
boundary
layers,
momentum.
Chemical
were
spatially
structured,
both
horizontally
vertically,
according
to
dominance
layers.
Microbes
associated
with
degradation
enriched
in
layers
surrounding
macroalgal-dominated
substrata.
Dominant
macroalgae
surrounded
by
a
distinct
pool
diverse
lipid
classes
(e.g.,
diterpenoids
glycerolipids)
labile
organic
matter
organooxygen
compounds),
which
diffused
from
algal
tissues
their
polarity.
Finally,
our
results
highlighted
strong
co-variations
between
specific
algal-derived
metabolites
planktonic
microbes,
giving
insight
into
roles
functioning
resilience.
Marine Drugs,
Год журнала:
2025,
Номер
23(4), С. 152 - 152
Опубликована: Март 31, 2025
Currently,
marine
algae
are
still
an
under-exploited
natural
bioresource
of
bioactive
compounds.
Seaweeds
represent
a
sustainable
source
for
obtaining
compounds
that
can
be
useful
the
fabrication
new
active
products
with
biomedical
benefits
and
applications
as
biomedicinals
nutraceuticals.
The
objective
this
review
is
to
highlight
scientific
papers
identify
biocompounds
from
macroalgae
emphasize
their
benefits.
method
used
was
data
analysis
systematize
information
various
in
pharmaceuticals,
cosmetics,
research
results
demonstrate
multiple
uses
seaweeds.
As
seaweeds
rich
sources
like
polysaccharides,
protein
compounds,
pigments,
polyphenols,
which
have
demonstrated
pharmacological
activities
such
antioxidant,
antibacterial,
anti-inflammatory,
antiviral,
anticoagulant,
potentially
anticarcinogenic
effects.
Seaweed
has
gained
recognition
functional
food
offers
unique
set
promote
body
health,
including
vitamins,
minerals,
antioxidants.
In
conclusion,
importance
expand
possibilities
utilizing
resources
by
broadening
areas
human
health
Marine Drugs,
Год журнала:
2023,
Номер
21(11), С. 578 - 578
Опубликована: Ноя. 5, 2023
Diseases
such
as
obesity;
cardiovascular
diseases
high
blood
pressure,
myocardial
infarction
and
stroke;
digestive
celiac
disease;
certain
types
of
cancer
osteoporosis
are
related
to
food.
On
the
other
hand,
world’s
population
increases,
ability
current
food
production
system
produce
consistently
is
at
risk.
As
a
result,
intensive
agriculture
has
contributed
climate
change
major
environmental
impact.
Research
is,
therefore,
needed
find
new
sustainable
sources.
One
most
promising
sources
raw
materials
macroalgae.
Algae
crucial
solving
this
nutritional
deficiency
because
they
abundant
in
bioactive
substances
that
have
been
shown
combat
hyperglycemia,
diabetes,
obesity,
metabolic
disorders,
neurodegenerative
diseases.
Examples
these
include
polysaccharides
alginate,
fucoidan,
agar
carrageenan;
proteins
phycobiliproteins;
carotenoids
β-carotene
fucoxanthin;
phenolic
compounds;
vitamins
minerals.
Seaweed
already
considered
nutraceutical
since
it
higher
protein
values
than
legumes
soy
becoming
increasingly
common.
compounds
extracted
from
seaweed
used
industry
thickening
agents
stabilizers
improve
quality
final
product
extend
its
shelf
life;
also
demonstrated
antidiabetic
effects.
Among
present
macroalgae,
compounds,
pigments,
fatty
acids
stand
out
due
their
different
properties,
antidiabetics,
antimicrobials
antioxidants,
which
important
treatment
or
control
cholesterol,
hyperglycemia
That
said,
there
some
studies
macroalgae
(red,
green
brown)
incorporated
into
foods,
but
on
gluten-free
products
still
scarce,
only
potential
use
for
type
considered.
Considering
aforementioned
issues,
review
aims
analyze
how
can
be
foods
supplement,
well
describe
contain,
beneficial
properties
human
health.
In
way,
macroalgae-based
eminent
diseases,
disease,
more
common
diabetes
cholesterol
complications,
seen.
Life,
Год журнала:
2022,
Номер
12(10), С. 1548 - 1548
Опубликована: Окт. 6, 2022
Abiotic
and
biotic
stress
factors
negatively
influence
the
growth,
yield,
nutritional
value
of
economically
important
food
feed
crops.
These
climate-change-induced
factors,
together
with
ever-growing
human
population,
compromise
sustainable
security
for
all
consumers
across
world.
Agrochemicals
are
widely
used
to
increase
crop
yield
by
improving
plant
growth
enhancing
their
tolerance
factors;
however,
there
has
been
a
shift
towards
natural
compounds
in
recent
years
due
detrimental
effect
associated
these
agrochemicals
on
crops
ecosystem.
In
view
these,
use
phenolic
biostimulants
as
opposed
artificial
fertilizers
gained
significant
momentum
production.
Seaweeds
marine
organisms
excellent
sources
that
useful
downstream
agricultural
applications
such
promoting
resilience
against
various
conditions.
this
review,
we
highlight
different
present
seaweed,
compare
extraction
methods,
describe
agriculture.
International Journal of Environmental Research and Public Health,
Год журнала:
2022,
Номер
20(1), С. 730 - 730
Опубликована: Дек. 30, 2022
Chronic,
low-grade
inflammation
is
linked
to
the
development
of
non-communicable
diseases,
including
cancer,
cardiovascular
disease,
obesity,
insulin
resistance,
diabetes,
and
others
which
together
contribute
more
than
50%
deaths
globally.
Modulation
inflammatory
responses
may
be
a
promising
strategy,
n-3
long
chain
polyunsaturated
fatty
acids
(n-3
LC-PUFA)
offer
new
therapeutic
option
in
conditions.
Seaweeds
are
characterised
by
high
nutritional
quality
good
source
many
bioactive
compounds,
LC-PUFA.
This
review
addresses
potential
anti-inflammatory
properties
seaweed
derived
lipids,
their
immunomodulating
mechanisms
order
identify
possible
applications
as
an
functional
food
ingredient
or
dietary
supplement.
A
few
studies
have
evaluated
activity
lipids
using
crude
lipid
extracts,
fractions
isolated
complex
from
several
seaweeds
belonging
Ochrophyta
Rhodophyta
phyla,
with
only
three
Ulva
rigida,
sp.
Codium
tomentosum
within
Chlorophyta
phylum.
It
was
reported
that
suppress
inducible
nitric
oxide
synthase
cyclooxygenase-2
expression
reduce
nuclear
factor
κB
p100
myeloid
differentiation
primary
response
88
protein
levels
leading
downregulation
production
pro-inflammatory
cytokines
oxide.
Further
investigations
required
unravel
underlying
preventive
action
against
chronic
use
and/or
health
Ecotoxicology and Environmental Safety,
Год журнала:
2024,
Номер
280, С. 116522 - 116522
Опубликована: Июнь 5, 2024
This
study
aimed
to
evaluate
the
effect
of
adding
liquid
extract
algae
(Hypnea
musciformis,
Grateloupia
acuminata,
and
Sargassum
muticum)
(HGS)
Magnesium
oxide
nanoparticles
(MgO
NPs)
using
this
rear
water
Oreochromis
niloticus,
on
improving
culture
indices,
growth
performance,
digestive
enzyme,
hemato-biochemical
characters,
immune,
antioxidative
responses,
resistance
after
challenged
by
Aeromonas
hydrophila
with
specific
refer
potential
role
mixture
in
vitro
as
against
three
strains
bacteria
(Aeromonas
sobria,
Pseudomonas
fluorescens,
P.
aeruginosa)
one
parasite
(Cichlidogyrus
tilapia).
The
first
group
represented
control,
HGS0,
whereas
other
group,
HGS5,
HGS10,
HGS15
mL
Marine Drugs,
Год журнала:
2024,
Номер
22(10), С. 478 - 478
Опубликована: Окт. 19, 2024
Macroalgae
are
known
as
abundant
sources
of
phytochemicals,
which
offer
a
plethora
beneficial
biological
properties.
Besides
being
the
most
notable
classes
compounds
found
in
macroalgae,
phlorotannins,
bromophenols,
and
terpenoids
comprise
some
relevant
for
their
Phlorotannins,
mainly
prevalent
brown
algae
structurally
characterized
complex
polyphenolic
derived
from
phloroglucinol
units,
possess
robust
antioxidant,
anti-inflammatory,
antitumor,
cytotoxic
activities,
modulated
by
factors
such
degree
polymerization
environmental
conditions.
Bromophenols,
halogenated
other
marine
organisms,
exhibit
significant
antioxidant
antiviral
Their
diverse
structures
bromination
patterns
contribute
to
potential
therapeutic
chemical
defense
agents.
Pigments
(chemically
described
primary
terpenoids)
play
critical
role
light
absorption
energy
transfer
macroalgae
divided
into
three
main
groups:
(i)
carotenoids,
primarily
provide
photoprotective
benefits;
(ii)
chlorophylls,
facilitating
conversion
energy;
(iii)
phycobilins,
mostly
red
important
roles
transfer,
besides
providing
remarkable
health
benefits.
Finally,
secondary
terpenoids,
particularly
(e.g.,
Rhodomelaceae
family)
central
cellular
interactions
antimicrobial,
antidiabetic,
anti-inflammatory
This
study
represents
detailed
analysis
biosynthesis,
structural
diversity,
activities
these
metabolites,
emphasizing
