Pharmaceutics,
Год журнала:
2024,
Номер
16(8), С. 1043 - 1043
Опубликована: Авг. 6, 2024
Chitosan
nanoparticles
(CSNPs)
are
promising
vehicles
for
targeted
and
controlled
drug
release.
Recognized
their
biodegradability,
biocompatibility,
low
toxicity,
ease
of
production,
CSNPs
represent
an
effective
approach
to
delivery.
Encapsulating
drugs
within
(NPs)
provides
numerous
benefits
compared
free
drugs,
such
as
increased
bioavailability,
minimized
toxic
side
effects,
improved
delivery,
the
incorporation
additional
features
like
release,
imaging
agents,
combination
therapies
with
multiple
drugs.
Keys
parameters
in
nanomedicines
loading
content
efficiency.
Most
current
NP
systems
struggle
loading,
presenting
a
significant
challenge
field.
This
review
summarizes
recent
research
on
developing
high
capacity,
focusing
various
synthesis
strategies.
It
examines
CSNP
using
different
materials
providing
details
methods,
loadings,
encapsulation
efficiencies,
release
profiles,
stability,
applications
Additionally,
discusses
factors
affecting
valuable
guidelines
future
CSNPs’
development.
Cells,
Год журнала:
2024,
Номер
13(5), С. 390 - 390
Опубликована: Фев. 24, 2024
Aging
populations
worldwide
are
placing
age-related
diseases
at
the
forefront
of
research
agenda.
The
therapeutic
potential
natural
substances,
especially
propolis
and
its
components,
has
led
to
these
products
being
promising
agents
for
alleviating
several
cellular
molecular-level
changes
associated
with
diseases.
With
this
in
mind,
scientists
have
introduced
a
contextual
framework
guide
future
aging
research,
called
hallmarks
aging.
This
encompasses
various
mechanisms
including
genomic
instability,
epigenetic
changes,
mitochondrial
dysfunction,
inflammation,
impaired
nutrient
sensing,
altered
intercellular
communication.
Propolis,
rich
array
bioactive
compounds,
functions
as
potent
functional
food,
modulating
metabolism,
gut
microbiota,
immune
response,
offering
significant
health
benefits.
Studies
emphasize
propolis'
properties,
such
antitumor,
cardioprotective,
neuroprotective
effects,
well
ability
mitigate
oxidative
stress,
DNA
damage,
pathogenic
bacteria
growth.
article
underscores
current
scientific
evidence
supporting
role
controlling
molecular
characteristics
linked
hallmarks,
hypothesizing
geroscience
research.
aim
is
discover
novel
strategies
improve
quality
life
older
individuals,
addressing
existing
deficits
perspectives
area.
Nanoscale,
Год журнала:
2024,
Номер
16(18), С. 8689 - 8707
Опубликована: Янв. 1, 2024
This
review
has
focused
on
the
up-to-date
development
of
targeted
drug
delivery
systems
to
GBM,
with
specific
emphasis
utilization
nanorobotic
for
active
targeting.
Applied Materials Today,
Год журнала:
2024,
Номер
38, С. 102179 - 102179
Опубликована: Апрель 4, 2024
Silica
coatings
have
emerged
as
a
key
player
in
the
realm
of
materials
science,
facilitating
transformative
bridge
between
traditional
nanoparticles
and
precision
molecular
design.
Silica,
renowned
for
its
adaptability
synthetic
versatile
properties,
stands
cornerstone
wide
array
applications.
Its
unique
capacity
to
finely
adjust
physicochemical
surface
characteristics,
encompassing
wettability,
charge,
chemical
composition,
morphology,
positions
silica
material
innovation.
This
Review
provides
comprehensive
exploration
role
coatings.
It
specifically
delves
into
synthesis,
implications
coatings,
highlighting
their
remarkable
respond
environmental
cues,
adapt
diverse
functionalities,
catalyze
innovative
research.
From
nanostructures
poised
revolutionize
science
intricate
world
biological
entities,
multifaceted
beckons,
reshaping
boundaries
biology
ways
both
profound
promising.
Polymers,
Год журнала:
2022,
Номер
14(8), С. 1611 - 1611
Опубликована: Апрель 15, 2022
Many
infections
are
associated
with
the
use
of
implantable
medical
devices.
The
excessive
utilization
antibiotic
treatment
has
resulted
in
development
antimicrobial
resistance.
Consequently,
scientists
have
recently
focused
on
conceiving
new
ways
for
treating
a
longer
duration
action
and
minimum
environmental
toxicity.
One
approach
infection
control
is
based
coatings
polymers
peptides,
also
termed
as
“natural
antibiotics”.
Nanomaterials,
Год журнала:
2022,
Номер
12(8), С. 1376 - 1376
Опубликована: Апрель 17, 2022
Mounting
evidence
shows
that
supplementation
with
vitamin
D
and
K
or
their
analogs
induces
beneficial
effects
in
various
diseases,
e.g.,
osteoarticular,
cardiovascular,
carcinogenesis.
The
use
of
drugs
delivery
systems
via
organic
inorganic
nanocarriers
increases
the
bioavailability
vitamins
analogs,
enhancing
cellular
effects.
nanotechnology-based
dietary
supplements
produced
by
food
pharmaceutical
industries
overcome
issues
associated
administration,
such
as
stability,
absorption
low
bioavailability.
Consequently,
there
is
a
continuous
interest
optimizing
carriers'
order
to
make
them
more
efficient
specific
for
targeted
tissue.
In
this
pioneer
review,
we
try
circumscribe
most
relevant
aspects
related
drug
delivery,
compare
different
types
nanoparticles
transportation,
critically
address
benefits
disadvantages.
Environmental Technology Reviews,
Год журнала:
2023,
Номер
12(1), С. 60 - 82
Опубликована: Фев. 20, 2023
Surfactants
and
nanoparticles
have
been
effectively
used
for
environmental
remediation
many
years.
Over
the
years,
various
methods
developed
to
synthesize
using
different
surfactants
obtain
a
s
higher
treatment
efficiency
organic
contaminated
soil.
Compared
conventional
methods,
in-situ
technique
provides
advantages,
such
as
being
more
eco-friendly
cost-effective.
This
review
an
overview
of
soil
surfactant-stabilized
Fe-based
nanoparticles,
mostly
nanoscale
zero-valent
iron
(nZVI).
In
addition,
use
other
stabilizers
mechanisms
stabilization
are
discussed.
The
combination
can
be
remediate
contaminants
from
soil,
trichloroethylene
(up
99%),
polychlorinated
biphenyls
80%),
perchloroethylene
93%).
in
by
is
than
only
surfactant
(less
90%)
or
80%)
due
synergistic
effects
between
nanoparticles.
generally
effective
strong
reductant,
reductive
dehalogenation
immobilization
metals,
while
less
cost-effective
adsorbent.
rate
depends
on
factors,
pH,
temperature,
natural
matter,
ionic
strength,
type
concentration
stabilizers,
site
characteristics,
contaminant
features,
nanoparticle
properties.
However,
short
lifetimes
potential
toxicity
some
limitations
this
technique.
International Journal of Nanomedicine,
Год журнала:
2021,
Номер
Volume 16, С. 5713 - 5743
Опубликована: Авг. 1, 2021
Abstract:
A
serious
viral
infectious
disease
was
introduced
to
the
globe
by
end
of
2019
that
seen
primarily
from
China,
but
spread
worldwide
in
a
few
months
be
pandemic.
Since
then,
accurate
prevention,
early
detection,
and
effective
treatment
strategies
are
not
yet
outlined.
There
is
no
approved
drug
counter
its
transmission.
However,
integration
nanostructured
delivery
systems
with
current
management
has
promised
pronounced
opportunity
tackle
This
review
addressed
various
promising
nanotechnology-based
approaches
for
diagnosis,
The
pharmaceutical,
pharmacoeconomic,
regulatory
aspects
these
currently
achieved
or
predicted
beneficial
outcomes,
challenges,
future
perspectives
also
highlighted.
Keywords:
nano-vaccine,
nano-theranostics,
nanoparticles,
nanotechnology,
SARS-CoV-2
