BACKGROUND
Digital
therapeutics
(DTx),
a
class
of
software-based
clinical
interventions,
are
promising
new
technologies
that
can
potentially
prevent,
manage,
or
treat
spectrum
medical
disorders
and
diseases
as
well
deliver
unprecedented
portability
for
patients
scalability
health
care
providers.
Their
adoption
implementation
were
accelerated
by
the
need
remote
during
COVID-19
pandemic,
awareness
about
their
utility
has
rapidly
grown
among
providers,
payers,
regulators.
Despite
this,
relatively
little
is
known
capacity
DTx
to
provide
economic
value
in
care.
OBJECTIVE
This
study
aimed
systematically
review
summarize
published
evidence
regarding
cost-effectiveness
clinical-grade
mobile
app–based
explore
factors
affecting
such
evaluations.
METHODS
A
systematic
evaluations
was
conducted
following
PRISMA
(Preferred
Reporting
Items
Systematic
Reviews
Meta-Analyses)
2020
guidelines.
Major
electronic
databases,
including
PubMed,
Cochrane
Library,
Web
Science,
searched
eligible
studies
from
inception
October
28,
2022.
Two
independent
reviewers
evaluated
eligibility
all
retrieved
articles
inclusion
review.
Methodological
quality
risk
bias
assessed
each
included
study.
RESULTS
total
18
this
Of
studies,
7
(39%)
nonrandomized
study–based
evaluations,
6
(33%)
model-based
5
(28%)
randomized
trial–based
The
intervention
subject
assessment
found
be
cost-effective
12
(67%)
cost
saving
1
(6%)
only
3
countries
where
it
being
deployed
final
Qualitative
deficiencies
methodology
substantial
potential
bias,
risks
performance
selection
participant
recruitment,
identified
several
studies.
CONCLUSIONS
supports
thesis
interventions
offer
benefits.
However,
analyses
date
exhibit
important
methodological
shortcomings
must
addressed
future
reduce
uncertainty
surrounding
widespread
interventions.
CLINICALTRIAL
PROSPERO
International
Prospective
Register
CRD42022358616;
https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022358616
World Journal of Clinical Cases,
Год журнала:
2024,
Номер
12(12), С. 2009 - 2015
Опубликована: Апрель 16, 2024
In
the
evolving
landscape
of
cardiac
rehabilitation
(CR),
adopting
digital
technologies,
including
synchronous/real-time
interventions
and
smart
applications,
has
emerged
as
a
transformative
approach.
These
technologies
offer
real-time
health
data
access,
continuous
vital
sign
monitoring,
personalized
educational
enhanced
patient
self-management
engagement.
Despite
their
potential
benefits,
challenges
limitations
exist,
necessitating
careful
consideration.
Synchronous/real-time
CR
involves
remote,
two-way
audiovisual
communication,
addressing
issues
accessibility
promoting
home-based
interventions.
Smart
applications
extend
beyond
traditional
healthcare,
providing
fostering
empowerment.
Wearable
devices
mobile
apps
enable
tracking
outcomes,
facilitate
lifestyle
modifications
crucial
for
maintenance.
As
progresses,
ensuring
equitable
implementation,
divide
becomes
paramount.
Artificial
intelligence
holds
promise
in
early
detection
events
tailoring
patient-specific
programs.
However,
such
literacy,
privacy,
security
must
be
addressed
to
ensure
inclusive
implementation.
Moreover,
shift
toward
raises
concerns
about
cost,
safety,
depersonalization
therapeutic
relationships.
A
towards
technologically
enabled
necessitates
further
research,
focusing
not
only
on
technological
advancements
but
also
customization
meet
diverse
needs.
Overcoming
related
security,
is
widespread
adoption
CR.
Future
studies
should
explore
integrating
moral
values
into
relationships
that
accessible,
equitable,
seamlessly
integrated
routine
care.
Theoretical
frameworks
accommodate
dynamic
quality
monitoring
feedback
feature
considered
guide
intervention
development.
Frontiers in Digital Health,
Год журнала:
2025,
Номер
7
Опубликована: Март 13, 2025
The
promotion
of
mental
health
is
essential
for
global
health,
affecting
millions
with
disorders
such
as
anxiety
and
depression.
Although
stigma
discrimination
hinder
progress,
these
conditions
are
often
preventable
or
manageable
at
minimal
cost.
adoption
digital
tools
in
promotion,
including
telemedicine,
online
therapy,
social
media,
wearables,
offers
promising
new
avenues
to
address
issues.
This
review
proposes
a
framework
that
focuses
on
the
use
enhance
literacy,
foster
behavioral
change,
support
sustained
positive
behaviors.
Platforms
TikTok,
Facebook,
Instagram
can
effectively
disseminate
information,
increase
awareness,
accountability.
Artificial
intelligence-driven
virtual
agents
offer
personalised
interventions,
providing
motivational
customised
advice.
Additionally,
wearable
technology
(e.g.,
fitness
trackers
smartwatches)
enables
real-time
monitoring
vital
metrics,
encouraging
ongoing
healthy
activities.
Nonetheless,
technologies
introduce
challenges
privacy
issues,
data
security,
equitable
access
resources,
raising
class
rights
protect
privacy,
guard
against
algorithm
bias,
prevent
personality-changing
manipulations.
absence
human
interaction
fully
solutions
also
raises
concerns
about
lack
empathy
emotional
connection.
For
optimal
integration
conventional
care
practices
adaptation
diverse
cultural
backgrounds
necessary.
results
this
suggest
tools,
when
carefully
implemented,
significantly
improve
outcomes
by
making
more
accessible,
tailored,
effective,
especially
underserved
communities.
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Янв. 6, 2024
This
trial
assessed
the
feasibility
and
acceptability
of
Kidney
BEAM,
a
physical
activity
emotional
well-being
self-management
digital
health
intervention
(DHI)
for
people
with
chronic
kidney
disease
(CKD),
which
offers
live
on-demand
sessions,
educational
blogs
videos,
peer
support.
In
this
mixed-methods,
multicentre
randomised
waitlist-controlled
internal
pilot,
adults
established
CKD
were
recruited
from
five
NHS
hospitals
1:1
to
BEAM
or
waitlist
control.
Feasibility
outcomes
based
upon
priori
progression
criteria.
Acceptability
was
primarily
explored
via
individual
semi-structured
interviews
(n
=
15).
Of
763
individuals
screened,
n
519
(68%,
95%
CI
65
71%)
eligible.
those
eligible,
303
(58%,
54-63%)
did
not
respond
an
invitation
participate
by
end
pilot
period.
216
responders,
50
(23%,
18-29%)
consented.
42
randomised,
22
(10
(45%)
male;
49
±
16
years;
14
(64%)
White
British)
allocated
20
(12
(55%)
56
11
15
(68%)
control
group.
Overall,
(30%,
18-45%)
withdrew
during
phase.
Participants
completed
median
(IQR
5-21)
sessions.
At
baseline,
90-100%
outcome
data
(patient
reported
measures
remotely
conducted
function
test)
62-83%
at
12
weeks
follow-up.
Interview
revealed
that
remote
procedures
acceptable.
Participants'
increased
their
opportunity
motivation
be
physically
active,
however,
lack
time
remained
ongoing
barrier
engagement
DHI.
An
controlled
is
feasible
acceptable,
adaptations
increase
recruitment,
retention
engagement.Trial
registration
NCT04872933.
Date
first
05/05/2021.
Journal of Medical Internet Research,
Год журнала:
2023,
Номер
25, С. e47094 - e47094
Опубликована: Июнь 28, 2023
Background
Digital
therapeutics
(DTx),
a
class
of
software-based
clinical
interventions,
are
promising
new
technologies
that
can
potentially
prevent,
manage,
or
treat
spectrum
medical
disorders
and
diseases
as
well
deliver
unprecedented
portability
for
patients
scalability
health
care
providers.
Their
adoption
implementation
were
accelerated
by
the
need
remote
during
COVID-19
pandemic,
awareness
about
their
utility
has
rapidly
grown
among
providers,
payers,
regulators.
Despite
this,
relatively
little
is
known
capacity
DTx
to
provide
economic
value
in
care.
Objective
This
study
aimed
systematically
review
summarize
published
evidence
regarding
cost-effectiveness
clinical-grade
mobile
app–based
explore
factors
affecting
such
evaluations.
Methods
A
systematic
evaluations
was
conducted
following
PRISMA
(Preferred
Reporting
Items
Systematic
Reviews
Meta-Analyses)
2020
guidelines.
Major
electronic
databases,
including
PubMed,
Cochrane
Library,
Web
Science,
searched
eligible
studies
from
inception
October
28,
2022.
Two
independent
reviewers
evaluated
eligibility
all
retrieved
articles
inclusion
review.
Methodological
quality
risk
bias
assessed
each
included
study.
Results
total
18
this
Of
studies,
7
(39%)
nonrandomized
study–based
evaluations,
6
(33%)
model-based
5
(28%)
randomized
trial–based
The
intervention
subject
assessment
found
be
cost-effective
12
(67%)
cost
saving
1
(6%)
only
3
countries
where
it
being
deployed
final
Qualitative
deficiencies
methodology
substantial
potential
bias,
risks
performance
selection
participant
recruitment,
identified
several
studies.
Conclusions
supports
thesis
interventions
offer
benefits.
However,
analyses
date
exhibit
important
methodological
shortcomings
must
addressed
future
reduce
uncertainty
surrounding
widespread
interventions.
Trial
Registration
PROSPERO
International
Prospective
Register
CRD42022358616;
https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022358616
Portuguese Journal of Public Health,
Год журнала:
2024,
Номер
42(2), С. 93 - 100
Опубликована: Янв. 1, 2024
Respiratory
diseases,
ranking
the
third
in
Portugal,
contribute
significantly
to
illness
and
mortality.
Chronic
obstructive
pulmonary
disease
(COPD)
is
third-leading
cause
of
death
globally.
Identifying
high-risk
individuals
implementing
early
treatment
crucial
due
variability
COPD
symptoms
exacerbations.
This
study
aimed
identify
effective
strategies
for
preventing
exacerbations
complications.
Bulletin of the World Health Organization,
Год журнала:
2025,
Номер
103(02), С. 136 - 147
Опубликована: Фев. 1, 2025
To
evaluate
the
adoption,
effectiveness
and
cost-effectiveness
of
digital
health
interventions
for
rheumatic
disease
management.
Between
25
May
2024
2
June
2024,
we
systematically
searched
PubMed®,
Scopus,
ClinicalTrials.gov,
Global
Observatory
eHealth
World
Bank
Open
Knowledge
Repository
randomized
controlled
trials
(RCTs)
evaluating
We
included
studies
published
between
2000
that
reported
on
adoption
rates
efficacy.
Two
reviewers
independently
screened
studies,
extracted
data
categorized
according
to
Health
Organization's
classification
interventions.
Of
455
unique
records
identified,
21
RCTs
met
inclusion
criteria.
Most
(15
studies)
focused
individual-centric
interventions,
such
as
targeted
communication,
personal
tracking,
educational
tools
wearable
devices.
Studies
in
high-income
countries
implemented
advanced,
integrated
combining
individual-focused
approaches
with
worker
services
using
telemedicine
platforms
decision
support
systems.
In
contrast,
low-
middle-income
adapted
accessible
technologies
mobile
messaging
telephone-based
education.
Many
telehealth,
significantly
improved
control,
patient
adherence,
knowledge
self-efficacy.
five
assessing
cost-effectiveness,
all
found
be
cost-effective.
Digital
show
promise
managing
diseases.
Tailoring
these
local
infrastructure
emphasizing
engagement
are
crucial
successful
adoption.
Future
research
should
focus
standardizing
evaluation
methods,
addressing
divides
enhancing
provider
services.
European Journal of Public Health,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 12, 2025
Abstract
Although
behavior
change
interventions
are
highly
recommended
in
health
care,
their
reach,
a
core
dimension
of
the
public
impact
interventions,
is
rarely
evaluated.
This
study
aimed
to
investigate
whether
an
individualized,
computer-based
brief
intervention
reduce
co-occurring
risk
behaviors
(HRBs),
namely
tobacco
smoking,
at-risk
alcohol
use,
insufficient
physical
activity,
and
unhealthy
diet,
can
reach
retain
sufficiently
large
part
general
hospital
patients
(>75%)
with
high
need,
that
more
HRBs,
low
school
education
or
current
unemployment
may
be
reached
retained.
Over
6
weeks
2022,
all
18–64-year-old
admitted
11
wards
five
medical
departments
university
Germany
were
asked
participate
HRB
screening
pre-post
three
further
assessments
individualized
computer-generated
feedback.
To
associations
between
retention
patient
characteristics,
logistic
Poisson
regression
analysis
used.
Screening
78.9%
eligible
(225/285).
Of
those
for
study,
81.8%
(175/214)
participated
intervention.
Among
these,
76.0%
(133/175)
at
least
once
after
hospitalization.
Patients’
lifestyle
socio-economic
characteristics
not
significantly
associated
retention,
Ps
≥
.467.
Proactive
multiple-HRB
patients,
including
most
need.
When
proven
efficacious
adequately
implemented,
this
promising
approach
concerning
reduction
non-communicable
diseases.
Trial
registration:
ClinicalTrials.gov
NCT05365269,
9
May
2022.
Populations
most
affected
by
cardiovascular
health
disparities,
including
underrepresented
populations
with
lower
socioeconomic
status,
people
disabilities,
and
those
living
in
underserved
rural
communities,
are
disproportionately
exposed
to
adverse
social
determinants
of
health.
Specifically,
economic
instability
suboptimal
conditions
within
the
neighborhood
built
environment
directly
determine
access
resources
opportunities
for
healthful
behaviors.
In
this
scientific
statement,
we
examined
technology-enabled
interventions
that
address
behaviors
from
adolescence
adulthood
disparities.
We
used
a
broad
definition
technology,
wearables,
applications,
telehealth,
behavior
tracking.
Aligning
Life’s
Essential
8,
focused
on
targeting
change
related
physical
activity,
sedentary
time,
dietary
intake,
tobacco
cessation,
sleep
improve
The
digital
important
adjuncts
operate
at
individual,
interpersonal,
community,
societal
levels.
include
impact
technologies
(eg,
telemedicine)
across
outcomes.
Evidence
effective
using
technology
through
positive
is
critical
preventing
disease
events.
Stronger
evidence
needed
inform
implement
approaches
scalable
cost-effective
communities
care
institutions
advance
equity
Dissemination
solutions
or
systems
must
ensure
effective,
feasible,
available,
affordable
need.
BACKGROUND
Heart
failure
remains
a
major
global
health
issue,
significantly
impacting
patients'
quality
of
life
due
to
its
chronic
and
progressive
nature.
Effective
discharge
planning,
including
educational
interventions
such
as
videos
booklets,
plays
crucial
role
in
enhancing
self-care
management
overall
patient
well-being.
OBJECTIVE
This
study
aims
measure
the
effects
planning
booklets
on
among
heart
patients.
METHODS
employed
quasi-experimental
was
conducted
at
PKU
Muhammadiyah
Gamping
Hospital
from
July
November
2024.
A
total
42
participants
who
met
inclusion
criteria
were
selected
based
sample
size
calculations
using
G*Power
evenly
assigned
intervention
control
groups.
Discharge
developed
tools
for
group.
The
independent
t-test
used
analyze
effect
intervention,
utilizing
SPSS
version
29.
RESULTS
improved
patients,
with
mean
score
decreasing
39.00
±
8.11
24.76
4.02
(p
=
0.000)
In
contrast,
group
showed
minimal
change
39.90
5.89
40.24
5.84,
resulting
statistically
significant
between-group
difference
15.58
0.000).
CONCLUSIONS
through
patients
compared
standard
care.
These
findings
emphasize
clinical
importance
structured
education,
suggesting
that
multimedia
printed
materials
can
enhance
self-management
