BACKGROUND
Digital
twins
(DTs)
are
digital
representations
of
real-world
systems,
enabling
advanced
simulations,
predictive
modeling,
and
real-time
optimization
in
various
fields,
including
health
care.
Despite
growing
interest,
the
integration
DTs
care
faces
challenges
such
as
fragmented
applications,
ethical
concerns,
barriers
to
adoption.
OBJECTIVE
This
study
systematically
reviews
existing
literature
on
DT
applications
with
three
objectives:
(1)
map
primary
(2)
identify
key
limitations,
(3)
highlight
gaps
that
can
guide
future
research.
METHODS
A
meta-review
was
conducted
a
systematic
fashion,
adhering
PRISMA-ScR
(Preferred
Reporting
Items
for
Systematic
Reviews
Meta-Analyses
extension
Scoping
Reviews)
guidelines,
included
25
published
between
2021
2024.
The
search
encompassed
5
databases:
PubMed,
CINAHL,
Web
Science,
Embase,
PsycINFO.
Thematic
synthesis
used
categorize
stakeholders,
RESULTS
total
3
were
identified:
personalized
medicine,
operational
efficiency,
medical
While
current
diagnostics,
patient-specific
treatment
hospital
resource
optimization,
remain
their
early
stages
development,
they
significant
potential
DTs.
Challenges
include
data
quality,
issues,
socioeconomic
barriers.
review
also
identified
scalability,
interoperability,
clinical
validation.
CONCLUSIONS
hold
transformative
care,
providing
individualized
accelerated
However,
adoption
is
hindered
by
technical,
ethical,
financial
Addressing
these
issues
requires
interdisciplinary
collaboration,
standardized
protocols,
inclusive
implementation
strategies
ensure
equitable
access
meaningful
impact.
CLINICALTRIAL
Journal of Medical Internet Research,
Год журнала:
2025,
Номер
27, С. e69544 - e69544
Опубликована: Янв. 24, 2025
Background
Digital
twins
(DTs)
are
digital
representations
of
real-world
systems,
enabling
advanced
simulations,
predictive
modeling,
and
real-time
optimization
in
various
fields,
including
health
care.
Despite
growing
interest,
the
integration
DTs
care
faces
challenges
such
as
fragmented
applications,
ethical
concerns,
barriers
to
adoption.
Objective
This
study
systematically
reviews
existing
literature
on
DT
applications
with
three
objectives:
(1)
map
primary
(2)
identify
key
limitations,
(3)
highlight
gaps
that
can
guide
future
research.
Methods
A
meta-review
was
conducted
a
systematic
fashion,
adhering
PRISMA-ScR
(Preferred
Reporting
Items
for
Systematic
Reviews
Meta-Analyses
extension
Scoping
Reviews)
guidelines,
included
25
published
between
2021
2024.
The
search
encompassed
5
databases:
PubMed,
CINAHL,
Web
Science,
Embase,
PsycINFO.
Thematic
synthesis
used
categorize
stakeholders,
Results
total
3
were
identified:
personalized
medicine,
operational
efficiency,
medical
While
current
diagnostics,
patient-specific
treatment
hospital
resource
optimization,
remain
their
early
stages
development,
they
significant
potential
DTs.
Challenges
include
data
quality,
issues,
socioeconomic
barriers.
review
also
identified
scalability,
interoperability,
clinical
validation.
Conclusions
hold
transformative
care,
providing
individualized
accelerated
However,
adoption
is
hindered
by
technical,
ethical,
financial
Addressing
these
issues
requires
interdisciplinary
collaboration,
standardized
protocols,
inclusive
implementation
strategies
ensure
equitable
access
meaningful
impact.
Healthcare,
Год журнала:
2025,
Номер
13(6), С. 665 - 665
Опубликована: Март 18, 2025
Background:
Mobile
health
(mHealth)
applications
play
a
crucial
role
in
enhancing
healthcare
accessibility,
patient
engagement,
and
chronic
disease
management.
However,
technical,
usability,
privacy-related
barriers
continue
to
hinder
their
widespread
adoption.
The
Sehaty
app,
government-managed
mHealth
platform
Saudi
Arabia,
is
widely
used
for
scheduling
medical
appointments,
accessing
records,
communicating
with
providers.
Understanding
the
challenges
associated
its
utilization
essential
optimizing
functionality
improving
user
experience.
Aim:
This
study
aims
identify
evaluate
key
affecting
adoption
usability
of
application
among
patients
conditions
Arabia.
Specifically,
it
examines
related
technical
performance,
privacy,
security
impact
on
satisfaction
engagement.
Methods:
A
cross-sectional
was
conducted
using
structured
questionnaire
distributed
344
participants
selected
through
purposive
sampling
ensure
inclusion
active
users
conditions.
assessed
10
primary
barriers,
including
issues,
navigation
difficulties,
privacy
concerns,
accessibility
limitations.
Descriptive
statistics
correlation
analyses
were
performed
prevalence
interrelationships
these
barriers.
Results:
findings
indicate
that
frequent
crashes,
slow
responsiveness,
system
instability,
significantly
satisfaction.
Usability
challenges,
such
as
difficulties
task
completion,
further
impede
Moreover,
concerns
emerged
significant
deterrents,
expressing
apprehensions
about
data
safety
transparency.
Accessibility
particularly
older
adults
individuals
disabilities,
insufficient
support
training,
making
app
less
user-friendly
populations.
highlights
interconnected
nature
suggesting
improvements
stability
interface
design
could
lead
enhanced
confidence,
overall
Conclusions:
Addressing
requires
targeted
enhancements,
user-centered
improvements,
strengthened
measures
promote
trust
Additionally,
implementing
comprehensive
systems
features
ensuring
equitable
access
services.
While
study’s
generalizability
limited
by
focus
single
platform,
offer
valuable
insights
applicable
broader
initiatives.
Future
research
should
incorporate
longitudinal
studies
assess
long-term
outcomes.
Healthcare,
Год журнала:
2025,
Номер
13(7), С. 740 - 740
Опубликована: Март 26, 2025
Background/Objectives:
Smartphones,
with
their
widespread
popularity
and
diverse
apps,
have
become
essential
in
our
daily
lives,
ongoing
advancements
information
technology
unlocked
significant
potential
healthcare.
Our
goal
is
to
identify
the
future
research
directions
of
mobile
health
(mHealth)
by
examining
its
trends
emerging
hotspots.
Methods:
This
study
collected
mHealth-related
literature
published
between
2005
2024
from
Web
Science
database.
We
conducted
a
descriptive
statistic
annual
publication
count
categorized
data
authors
institutions.
In
addition,
we
developed
visualization
maps
display
frequency
keyword
co-occurrences.
Furthermore,
overlay
visualizations
were
created
showcase
average
year
specific
keywords,
helping
track
changing
mHealth
over
time.
Results:
Between
2024,
total
6093
papers
related
published.
The
revealed
rapid
increase
number
publications
since
2011.
However,
it
was
found
that
on
has
reached
saturation
point
2021.
University
California
dominant
force
research,
248
articles.
California,
London,
Harvard
University,
Duke
are
actively
collaborating,
which
shows
geographical
pattern
collaboration.
From
analysis
co-occurrence
timeline,
focus
gradually
shifted
solely
technologies
exploring
how
new
technologies,
such
as
artificial
intelligence
(AI)
can
intervene
patient
conditions,
including
breast
cancer,
diabetes,
other
chronic
diseases.
Privacy
protection
policies
transparency
mechanisms
emerged
an
active
current
development.
Notably,
cutting-edge
Internet
Things
(IoT),
blockchain,
virtual
reality
(VR)
being
increasingly
integrated
into
systems.
These
technological
convergences
likely
constitute
key
priorities
field,
particularly
addressing
security
vulnerabilities
while
enhancing
service
scalability.
Conclusions:
Although
volume
core
declining,
practical
applications
continue
expand
across
domains,
integrating
multiple
technologies.
It
believed
still
holds
enormous
potential.
International Journal of Women s Health,
Год журнала:
2025,
Номер
Volume 17, С. 87 - 98
Опубликована: Янв. 1, 2025
The
psychological
experiences
will
be
analyzed
to
understand
the
needs
and
burdens
of
women
on
day
oocyte
retrieval
when
thawed
testicular
sperm
their
husbands
is
used
for
in
vitro
fertilization,
order
provide
a
basis
subsequent
formulation
relevant
nursing
measures.
This
study
utilized
descriptive
phenomenological
research
approach.
A
cohort
13
undergoing
from
fertilization
at
Reproductive
Medicine
Center
Sir
Run
Shaw
Hospital,
Zhejiang
University
School
Medicine,
between
August
October
2024,
were
chosen
as
participants
this
study.
Semi-structured,
in-depth
interviews
conducted
gather
qualitative
data.
Colaizzi
7-step
analysis
method
was
subsequently
analyze
interview
transcripts
identify
emerging
themes.
yielded
3
themes:
(1)
facing
challenges
requiring
assistance
(a.
demonstrate
strong
desire
acquire
professional
knowledge;
b.
recognition);
(2)
overwhelming
stress
concerns
about
potential
privacy
breaches;
security
issues;
c.
therapeutic
efficacy);
(3)
improving
family
atmosphere
marital
relationships
communication
couples
has
increased.;
shared
expectations
children
help
establish
common
goal).
It
recommended
that
healthcare
practitioners
implement
strategies
enhance
patient
education
awareness
surrounding
assisted
reproductive
technology.
Additionally,
establishing
strengthening
social
support,
reinforcing
protections
safety
measures,
promoting
effective
partners,
managing
treatment
outcome
are
crucial
steps
forward.
Women
prioritize
efficacy,
preservation,
necessity
acquiring
comprehensive
knowledge
employing
partner's
fertilization.
instrumental
shaping
policy
dialogues
health,
highlighting
critical
significance
women's
health
realm
Introduction
Digital
mental
health
(DMH)
enhances
access
to
healthcare,
particularly
in
low-
and
middle-income
countries
where
investment
healthcare
is
low.
However,
utilization
among
young
people
(YP)
This
study
aimed
explore
YP's
perceptions
of
the
barriers
using
DMH
interventions
low-resource
settings.
Methods
A
qualitative
descriptive
approach
was
used.
Six
face-to-face
focus
group
discussions
were
conducted
with
50
YP
from
nine
universities
Uganda.
The
median
age
24
years
(range
21–25
years)
respondents
drawn
diverse
academic
programmes
majority
being
medical
students
(54%).
thematic
used
interpret
results.
Results
Three
themes
identified
data
including
services,
perceived
utilization,
suggestions
for
enhancement
Most
had
a
positive
attitude
towards
DMH.
included
fear
stigma,
affordability,
inequitable
access,
privacy
confidentiality
concerns,
app-related
challenges.
Access
use
can
be
enhanced
through
public
engagement,
creating
awareness,
training,
affordable
interventions.
Conclusion
deemed
important
extending
YP,
systems
traditional
services
are
not
readily
available.
several
factors
hinder
equitable
There
need
long-term
digital
technologies.
JMIR Aging,
Год журнала:
2025,
Номер
8, С. e69175 - e69175
Опубликована: Фев. 25, 2025
Background
Using
remote
monitoring
technology
in
the
context
of
Alzheimer
disease
(AD)
care
presents
exciting
new
opportunities
to
lessen
caregiver
stress
and
improve
patient
quality.
The
application
wearables,
environmental
sensors,
smart
home
systems
designed
specifically
for
patients
with
AD
represents
a
promising
interdisciplinary
approach
that
integrates
advanced
health
enhance
safety,
monitor
parameters
real
time,
provide
comprehensive
support
caregivers.
Objective
objectives
this
study
included
evaluating
effectiveness
various
sensing
technologies
enhancing
outcomes
identifying
strategies
alleviate
burden
on
professionals
Critical
elements
such
as
regulatory
compliance,
user-centered
design,
privacy
security
considerations,
overall
efficacy
relevant
were
comprehensively
examined.
Ultimately,
aimed
propose
framework
tailored
needs
related
dementias.
Methods
Guided
by
PRISMA
(Preferred
Reporting
Items
Systematic
Reviews
Meta-Analyses)
framework,
we
conducted
systematic
review
Our
search
spanned
4
major
electronic
databases—Google
Scholar,
PubMed,
IEEE
Xplore,
DBLP
February
20,
2024,
an
updated
May
18,
2024.
Results
A
total
31
publications
met
inclusion
criteria,
highlighting
key
research
areas:
existing
technologies,
balancing
practicality
empathy,
monitoring,
design
care.
studies
revealed
strong
focus
methods
capturing
behavioral,
physiological,
data
yet
showed
gap
these
needs,
privacy,
usability.
findings
also
indicated
many
lacked
robust
reference
standards
did
not
consistently
apply
critical
appraisal
underlining
need
frameworks
better
integrate
essential
considerations.
Conclusions
This
literature
provides
understanding
trends,
gaps
current
significance
novel
reduce
among
proposed
aims
inspire
development
models
advance
AD.
Journal of Medical Internet Research,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 30, 2025
Despite
extensive
research
into
technology
users'
privacy
concerns,
a
critical
gap
remains
in
understanding
why
individuals
adopt
different
standards
for
data
protection
across
contexts.
The
rise
of
advanced
technologies
such
as
the
Internet
Things
(IoT),
artificial
intelligence
(AI),
augmented
reality
(AR),
and
big
has
created
rapidly
evolving
complex
landscapes.
However,
is
often
treated
static
construct,
failing
to
reflect
fluid,
context-dependent
nature
user
concerns.
This
oversimplification
led
fragmented
research,
inconsistent
findings,
limited
capacity
address
nuanced
challenges
posed
by
these
technologies.
Understanding
dynamics
especially
crucial
fields
digital
health
informatics,
where
sensitive
trust
are
central
adoption
ethical
innovation.
study
synthesized
existing
on
behaviors
emerging
technologies,
focusing
IoT,
AI,
AR,
data.
Its
primary
objectives
were
identify
psychological
antecedents,
outcomes,
theoretical
frameworks
explaining
behavior,
assess
whether
insights
from
traditional
online
literature,
e-commerce
social
networking,
apply
It
also
advocates
approach
privacy.
A
systematic
review
179
studies
related
Following
established
guidelines
using
leading
databases
ScienceDirect
(Elsevier),
SAGE,
EBSCO,
screened
relevance
behaviors,
focus
empirical
grounding.
Methodological
details
analyzed
applicability
findings
networking
today's
revealed
key
gaps
literature
Contextual
factors,
sensitivity,
recipient
transparency,
transmission
principles,
overlooked,
despite
their
role
shaping
concerns
behaviors.
showed
that
theories
developed
fall
short
addressing
complexities
modern
By
synthesizing
behavioral
frameworks,
this
underscores
need
context-contingent
research.
advances
emphasizing
context
sharing,
particularly
amid
ubiquitous
challenge
views
highlight
tailored
dynamic,
Practical
implications
include
guiding
care
providers,
policy
makers,
developers
toward
context-sensitive
strategies
build
trust,
enhance
protection,
support
PROSPERO
CRD420251037954;
https://www.crd.york.ac.uk/PROSPERO/view/CRD420251037954.
