Journal of Medicinal and Chemical Sciences,
Год журнала:
2022,
Номер
6(4)
Опубликована: Ноя. 6, 2022
Neonatal
sepsis
refers
to
the
bacterial
bloodstream
infections
of
newborn
during
neonatal
period
as
usually
first
twenty-eight
days
life.
The
current
study
was
done
in
laboratories
AL-Batool
Teaching
Hospital
for
Gynecology
and
Pediatrics
Baqubah,
Diyala
Governorate,
including
140
blood
specimens
collected
from
neonates
admitted
hospital
with
suspected
sepsis,
ages
both
groups
ranged
1
day
28
days.
Out
total
cultured
samples,
32.14%
(45
140)
were
positive
67.86%
(95
negative
culture.
45
samples
culture
chosen
control
group.
results
showed
highest
isolates
Coagulase
Negative
Staphylococcus
(CoNS)
19
(42.2%),
followed
by
aureus
11
(24.5%),
Escherichia
coli
4
(8.8%),
Klebsiella
pneumonia
Acinetobacter
baumannii
3
(6.7%),
Group
B
Streptococcus
(GBS),
Pseudomonas
aeruginosa
2
(4.5%).
Ceftazidime
antibiotic
has
resistance
percentage
CIP,
CXM,
AMP,
NA,
C,
CD,
CL
among
studied
isolates.
Biofilm
formation
all
K.
pneumonia,
A.baumannii,
P.aeruginosa,
GBS
100%
can
form
biofilm,
while
S.aureus,
CoNS
E.coli
6
(53.55%),
7
(36.84%),
(50%)
biofilm
forming,
respectively.
These
biofilm-forming
exhibited
high
AK,
AMC,
TM,
CTX,
NE,
VAN,
COT,
CL,
CAZ,
CIP.
Journal of Medicinal and Chemical Sciences,
Год журнала:
2022,
Номер
5(6)
Опубликована: Июнь 12, 2022
Microbial
infection
and
microbial
resistance
to
the
classical
antibiotics
have
been
immense
challenges
which
portend
health
of
societies.
This
has
directed
researchers
straight
their
attention
onto
plants
discover
new
possible
antimicrobial
compounds.
In
this
work,
5
solvents
were
employed
extract
dried
seeds
powder
quince
by
ultrasound
including
ethanol,
ethyl-acetate,
chloroform,
n-hexane,
diethyl-ether.
Each
was
subjected
three
in
vitro
tests
using
broth-dilution
method.
The
antibacterial
effect
against
following
aerobic
bacteria
are
Pseudomonas
aeruginosa
ATCC
27853,
Klebsiella
pneumonia
700603,
Haemophilus
influenzae
49247,
Escherichia
coli
25922,
Salmonella
typhi
6539,
Shigella
dysenteriae
13313,
non-pathogenic
BAA-1427
applying
ciprofloxacin
antibiotic
as
a
standard
reference,
study
anaerobic
include
Bacteroides
fragilis
25285,
Clostridium
perfringens
13124,
Fusobacterium
necrophorum
25286,
Prevotella
melaninogenica
25845
employing
metronidazole
antifungal
versus
Candida
albicans
10231
Aspergillus
niger
16888,
nystatin
reference.
toxicity
normal
bacterial
flora
evaluated
verify
safety
profile
extracts.
results
revealed
that
extracts
activities
with
supremacy
linked
ethanol
extract.
accordance
activity
evidence
values,
displayed
bactericidal
fungicidal
activities,
having
least
harmful
strain.
Journal of Medicinal and Chemical Sciences,
Год журнала:
2023,
Номер
unknown
Опубликована: Авг. 3, 2023
Aromatase
inhibitors
(AI)
are
commonly
used
adjuvant
therapy
drugs
for
women
with
hormone
receptor-positive
postmenopausal
breast
cancer.
Frequently
AI
associated
side
effects
include
severe
joint
and
muscle
pain.
Inhibitor
-
Associated
Musculoskeletal
Syndrome
(AIMSS)
is
a
condition
that
primarily
affects
the
hands,
wrists,
knees.
This
study
aimed
to
determine
efficacy
of
Moringa
oleifera
extract
as
an
when
taken
cancer
patients
ER
(+),
PR
observed
CPK
levels
inflammation
indicators.
The
Functional
Assessment
Cancer
Therapy-Breast
(FACT-B)
can
assess
subjects’
emotional,
physical,
functional
well-being,
social,
also
subscale.
research
sample
consisted
40
(+)
immunohistochemistry
outpatients
at
Kasuari
facility,
Dr.
Kariadi
Semarang,
who
experienced
pain
due
administration
aromatase
inhibitors.
results
changes
in
FACT-B
scores
group
received
additional
were
obtained
this
study.
treatment
showed
level
post-test
lower
than
pre-test
(105.30
±
50.19
vs.
88.10
48.24,
p
<0,001).
In
addition,
score
control
(83.45
5.11
75.25
4.05,
p<0,001).
has
strong
anti-inflammatory
effect
especially
patient
post-menopause
inhibitor
treatment.
Its
properties
will
upgrade
patient’s
quality
life,
adherence,
long
period
outcomes.
