Research Square (Research Square),
Год журнала:
2023,
Номер
unknown
Опубликована: Сен. 27, 2023
Abstract
Worldwide
aging
population
continues
to
increase,
so
the
concept
of
healthy
longevity
medicine
has
become
increasingly
significant
in
modern
society.
Berberis
vulgaris
L.
fruits
serve
as
a
functional
food
supplement
with
high
concentration
bioactive
compounds,
which
offer
numerous
health-promoting
benefits.
The
goal
this
study
was
investigate
geroprotective
effect
extract.
Here
we
show
that
extract
can,
depending
on
concentrate,
increase
lifespan
up
6%,
promote
healthspan
(stress
resistance
35%,
locomotor
activity
25%,
integrity
intestinal
barrier
12%,
metabolic
rate
5%)
Drosophila
melanogaster
(
vitro
)
and
exhibits
antioxidant
(using
red
blood
cell
tests)
antiglycation
glycation
bovine
serum
albumin)
).
In
addition
this,
does
not
exhibit
cytotoxic
properties
,
unlike
well-known
polyphenolic
compound
quercetin.
qRT-PCR
revealed
involvement
metabolic,
heat
shock
response
lipid
metabolism
genes
observed
effects.
Functional Food Science - Online ISSN 2767-3146,
Год журнала:
2023,
Номер
3(5), С. 55 - 55
Опубликована: Май 31, 2023
Functional
food
science
has
witnessed
remarkable
advancements
in
recent
years,
driven
by
our
evolving
understanding
of
quantum
mechanics
and
the
concept
time.
The
interplay
between
these
two
theories,
namely
Quantum
theory
Tempus
theory,
opened
new
avenues
for
research
innovation
functional
food.
integrates
theories
to
better
understand
complex
relationship
food,
chronic
disease,
health.
explores
molecular-level
energy,
matter,
bioactive
compounds
foods,
optimizing
their
development
utilization
disease
emphasizes
timed
consumption,
aligning
foods
with
circadian
rhythms
metabolic
processes
enhanced
nutrient
absorption,
utilization,
responses.
By
synchronizing
intake
body's
natural
rhythms,
enhances
efficacy
promoting
health
preventing
disease.
Integrating
tempus
provides
a
comprehensive
approach
utilizing
potential
personalized
nutritional
interventions
improving
overall
well-being.Keywords:
science,
compounds,
cellular
interactions,
timing,
promotion,
nutrition.
Bioactive Compounds in Health and Disease - Online ISSN 2574-0334 Print ISSN 2769-2426,
Год журнала:
2022,
Номер
5(6), С. 117 - 117
Опубликована: Июнь 24, 2022
Background:
Squalene,
in
recent
years,
has
become
a
topic
of
interest
to
scientists
due
its
potential
health
benefits
and
anti-inflammatory
effects.
Squalene
is
hydrocarbon
belonging
the
triterpene
class;
it
30-carbon
isoprenoid
compound.
In
previous
studies,
amaranth
oil,
containing
high
amounts
squalene,
was
shown
function
as
an
effective
treatment
option
for
reducing
proteinuria,
one
key
markers
renal
disease.
Objectives:
Our
main
goal
understand
effect
squalene
biotic
agent
proteinuria.
order
identify
decreasing
proteinuria
we
conducted
experimental
study
on
diabetic
patients.
research
focused
patients
with
type
2
diabetes
mellitus
separate
dosages
serum
consumption.
Over
course
84
days,
tracked
changes
levels
based
dosage
consumed.
addition
this,
testing
also
days
various
related
parameters.
These
parameters
include
blood
urea
nitrogen
(BUN),
cystatin
C,
albumin,
systolic
diastolic
pressure,
transforming
growth
factor
b1
(TGFB1).
By
assessing
throughout
study,
hoped
analyze
relationship
between
these
associated
parameters.Methods:
Five
groups
30
people,
totaling
150
volunteers,
were
recruited
into
study.
group
1,
healthy
people
served
group.
2,
T2DM
did
not
consume
any
thereby
serving
control
Group
3
consisted
who
consumed
200
mg
(extracted
from
shark
liver)
daily.
4
400
Lastly,
5
600
3,
4,
5,
prescribed
total
consecutive
days.
Among
referred
Vali-Asr
medical
laboratory
(Tehran,
Iran),
120
selected.
Also,
participated
individuals.
Regarding
World
Health
Organization,
inclusion
criteria
included
following:
fasting
plasma
glucose
≥
126
mg/dL,
glycated
hemoglobin
(HbA1c)
6.5%,
taking
corticosteroids.
Informed
consent
obtained
all
volunteers.
Results:
Throughout
decreased
statistical
significance.
A
positive
correlation
observed
amount,
there
had
been
higher
level
decrease
amount
administered
Statistical
significance
found
well
tested
(BUN,
Albumin
(AL),
creatinine
(CR),
TGFbeta1.
Conclusion:
All
indicative
alongside
count
showed
trend
overall
reduction
duration
values
vary
time
elapsed
initial
prescription.
Based
results,
may
be
assumed
that
functions
effectively
reduce
level.Keywords:
disease,
diabetes,
functional
food,
oil
Functional Food Science - Online ISSN 2767-3146,
Год журнала:
2023,
Номер
3(5), С. 45 - 45
Опубликована: Май 31, 2023
The
objective
of
this
literature
review
was
to
evaluate
the
effectiveness
exploring
lactobacillus
probiotics
in
weight
management:
a
management.
Obesity
is
defined
as
accumulation
excessive
fat,
which
may
result
many
potential
health
risks.
A
body
mass
index
over
30
considered
obese,
and
obesity
rates
have
increased
by
400%
since
1975.
one
leading
underlying
causes
issues
developed
nations,
causing
problems
such
cardiovascular
disease,
stroke,
certain
cancers.
Additionally,
also
known
be
heavily
associated
with
type
ii
diabetes,
high
blood
pressure
(hypertension),
musculoskeletal
disorders.
To
combat
connected
obesity,
diet,
exercise
are
essential.
In
article,
we
recommend
use
probiotics’
biocompound
from
genus
addition
diet
an
intervention
for
obese
individuals.
Probiotics
facilitate
loss
increasing
microbiome
quantity
variety,
regulating
immune
responses,
improving
metabolic
rates.
An
online
search
conducted
following
databases:
pubmed®
functional
food
center’s
journal
database.
Studies
published
between
January
1,
2010,
April
2023,
were
included.
More
rcts
needed
increase
certainty
evidence
verify
our
conclusions,
especially
those
who
conditions
that
comorbid
2
diabetes.Another
major
research
will
reviewing
accumulated
data
perspective
definition
steps
on
how
create
ideal
products.
Functional
foods,
products
contain
bioactive
compounds,
vitamins,
minerals,
antioxidants,
other
beneficial
substances,
crucial
promoting
preventing
diseases.
science
involves
isolating
combining
compounds
ingredients
provide
targeted
benefits.
development
incorporates
multidisciplinary
approach
science,
nutrition,
biotechnology,
related
fields.
Hence,
accumulating
using
quantum
end
tempus
theories
about
researchers
can
valuable
insights
creating
innovative
meet
consumer
demands
healthier
options.
Keywords:Obesity,
probiotics,
Lactobacillus,
theory
diabetes
Functional Food Science - Online ISSN 2767-3146,
Год журнала:
2024,
Номер
4(8), С. 299 - 308
Опубликована: Авг. 9, 2024
Background:
To
satisfy
the
need
for
thorough
yet
flexible
food
safety
guidelines,
GRAS
(Generally
Recognized
as
Safe)
certification
process
was
introduced
in
1958,
establishing
a
products
and
additives
to
be
considered
safe
consumption.
It
involves
multitude
of
steps
from
multiple
parties:
author
advocating
their
new
product,
group
panelists
who
will
evaluate
FDA
(Food
Drug
Administration),
has
final
say
status
product.
The
first
step
submitting
documents
with
basic
information
product
details,
including
lab
trials
experimentation.
Next,
follow
guidelines
carefully
its
context
intended
usage.
reviewing
evidence
both
previous
groups
reaches
singular
conclusion
that
determine
at
end.
Overall,
established
concrete
set
products.
Different
conclusions
levels
were
produced
general
standard
companies
other
organizations
abide
by.
These
different
procedures
are
all
required
maintain
highly
renowned
overall
standardized
level
quality
exported
United
States.
This
article
also
candidacy
functional
products,
comparing
processes
regards
sending
market
notification
overall.
Functional
foods
proved
an
excellent
candidate
process,
passing
every
component
requirements
serving
great
example
exactly
what
authors
should
expecting
when
putting
through
procedure.
Keywords:
GRAS,
notification,
Bioactive Molecules and Pharmaceuticals,
Год журнала:
2022,
Номер
1(9), С. 1 - 1
Опубликована: Сен. 13, 2022
Armenia
has
a
rich
history
of
medicine
and
fermented
foods.
Fermented
milk
products
are
enjoyed
both
as
gustatory
pleasure
digestive
remedy.
Matsun
is
traditional
Armenian
product
with
historico-cultural
roots
in
ancient
subsistence
medical
practices.
Unlike
commercial
yogurt,
it
made
through
serial
inoculation
consists
large
microbial
diversity
honed
centuries
human
selection.
Also
from
matsun
choratan,
long-
keeping
dried
version
that
can
be
reconstituted
into
creamy
base.
Narine
the
name
Lactobacillus
acidophilus
INMIA
9602,
bacterial
strain
endemic
to
microbiome
newborns
often
used
food.
Both
choratan
have
been
clinical
trials
for
management
symptoms
related
gut
dysbiosis.
The
review
cell
cultures
animal
revealed
source
probiotics
antimicrobial,
antifungal,
radioprotective
activity
due
peptides
released
protease
resistant
bacteriocins
produced.
Clinical
studies
needed
confirm
effects
combined
strains
establish
dosages.
Choratan
an
isolated
showed
some
effect
on
imbalance,
but
more
results.
well-studied
several
preclinical
small
accepted
For
future
functional
food
consideration,
replications
trials,
scale
epidemiological
aftermarket
needed.Keywords:
Matsun,
Choratan,
Narine,
History
Medicine,
foods,
bioactive
compounds,
9602
Functional Food Science - Online ISSN 2767-3146,
Год журнала:
2022,
Номер
2(11), С. 258 - 258
Опубликована: Ноя. 25, 2022
Over
the
years
United
States
has
seen
an
increase
in
prevalence
of
chronic
diseases.
For
that
reason,
there
also
been
increased
need
products
can
prevent
or
manage
symptoms
disease.
Functional
food
are
contain
bioactive
compounds
have
shown
to
produce
beneficial
effects
health.
The
Food
Center
previously
a
16-step
process
develop
functional
and
bring
them
market.
As
part
this
process,
researchers
should
establish
appropriate
dosage
compound
at
which
product
be
consumed
safely,
it
effectively
improve
health
parameters.
Previously,
we
suggested
Quantum
theory
science
could
useful
for
finding
critical
amount
will
cause
enough
chain
reactions
influence
biomarkers
In
paper,
propose
new
step
added
making
total
steps
market
17.
This
occur
after
establishing
dose
focus
on
time
consumption
using
Tempus
science.
word
comes
from
latin
time.
Similar
dosage,
impact
effectiveness
compound,
is
why
important.
Recent
studies
diabetic
patients
applied
theories
determine
range
squalene,
belonging
triterpene
class,
parameters
diabetics.
found
squalene
improves
patients,
however
higher
doses
produced
less
than
lower
doses.
Although
were
able
provide
more
information
about
consuming
population,
research
needed
find
exact
ranges.Keywords:
product,
time,
quantum
science,
tempus
Functional Foods in Health and Disease,
Год журнала:
2023,
Номер
13(9)
Опубликована: Сен. 11, 2023
Health
claims
are
essential
for
providing
accurate
information
about
the
relationship
between
nutrients
and
health
outcomes
to
consumers.
They
facilitate
informed
decision-making
support
individuals
in
making
healthy
dietary
choices.
The
U.S.
Food
Drug
Administration
(FDA)
regulates
guide
consumers
maintaining
practices.
on
food
labels
help
understand
potential
benefits
associated
with
specific
products
make
choices
aligned
their
goals.
These
also
promote
transparency
trust
industry
by
evidence-based
information.
process
of
submitting
a
claim
FDA
involves
complying
regulatory
requirements
robust
scientific
evidence.
Scientific
evidence
plays
crucial
role
substantiating
should
be
based
well-designed
clinical
trials,
epidemiological
studies,
mechanistic
research.
Adhering
labeling
ensures
informative
presentation
labels.
Functional
Center
(FFC)
is
working
theoretical
aspects
creating
ideal
functional
(FF)
as
well
how
these
identified
special
FF
While
focuses
evaluating
claims,
FFC
emphasizes
safe
effective
use
foods.
Understanding
FDA's
evaluation
FFC's
guidelines
researchers,
manufacturers,
policymakers
navigate
landscape
consumer
Compliance
guidelines,
adherence
standards,
clear
communication
contribute
more
health-conscious
society.Keywords:
outcomes,
requirements,
foods,
Bioactive Compounds in Health and Disease - Online ISSN 2574-0334 Print ISSN 2769-2426,
Год журнала:
2024,
Номер
7(1), С. 1 - 1
Опубликована: Янв. 15, 2024
Background:
The
problem
of
aging
remains
relevant
in
the
modern
world,
with
a
notable
connection
between
and
nutrition.
It
is
important
to
find
way
slow
down
aging.
Integration
lymphology
functional
food
theory
(or
phytodietics)
most
promising
idea.
Detection
lymphotropic
properties
bioactive
ingredients
will
increase
lymphatic
system
activity
Our
task
improve
protective
status
lymph
nodes
by
taking
phytomineral
product
Objective:
research
purpose
provide
evidence
use
plant-mineral
complex
activate
(lymph
nodes)
Participants
experiment
are
160
Wistar
rats
divided
into
groups
old
young
animals.
Half
animals
took
an
additional
"IQdetoxSORB".
basis
physiologically
acting
substances
such
as
flavonoids,
trace
elements,
fibers,
others.Methods:
Different
methods
have
been
applied
study
systems
forming
components
nodes.
node
compartments
was
examined
histological
method.
liquid
component
organ
evaluated
thermogravimetric
Lymph
elements
(Mn,
Fe,
Cu,
Zn,
Se)
were
determined
X-ray
fluorescence
analysis
using
synchrotron
radiation
(RFA
SR).
StatPlus
Pro
license
program
statistical
dynamic
series
used
process
digital
data.Results:
We
first
presented
data
on
effect
nutrition
proved
complex.
(flavonoids,
fibers)
useful
influence
system,
improving
health
age.
occurs
through
implementation
lymphosanation
mechanism
due
stimulating
effects
plant
ingredients.
Intake
accelerates
flow,
modifies
compartments,
restores
element
balance.
positive
depends
formation
association
bioelements
lymphoid
compartments.
A
plant-based
diet
corrects
increases
result
slowdown
age-induced
changes
peripheral
organs.
Conclusion:
As
nutrition,
contains
-
fibers.
These
alter
existing
increasing
potential.
Increased
argument
for
slowing
preventing
age-associated
pathology.
information
recommending
complexes
wellness
programs
anti-aging.Keywords:lymphatic
system;
nodes;
compartments;
elements;
gerontology,
phytotherapy,
nutriciology.