This
dissertation
seeks
to
identify
and
problematize
diverse
social
actors'
views
concerns
about
gene
edited
foods
crops
(GEC).
As
new
forms
of
agricultural
biotechnologies
that
are
still
largely
in
the
development
phase,
their
eventual
impacts
uncertain,
but
interested
actors
actively
working
influence
trajectory
GECs.
The
three
empirical
chapters
present
research
adds
existing
editing
governance
literature
by
examining
perspectives
contexts
groups.
findings
illustrate
potential
barriers,
opportunities,
tensions
which
may
need
be
resolved
if
promises
realized.
Implications
for
discussed.
Frontiers in Plant Science,
Год журнала:
2022,
Номер
13
Опубликована: Ноя. 8, 2022
Genetic
modification
of
crops
has
substantially
focused
on
improving
traits
for
desirable
outcomes.
It
resulted
in
the
development
with
enhanced
yields,
quality,
and
tolerance
to
biotic
abiotic
stresses.
With
advent
introducing
favorable
into
crops,
biotechnology
created
a
path
involvement
genetically
modified
(GM)
sustainable
food
production
systems.
Although
these
plants
heralded
new
era
crop
production,
their
widespread
adoption
faces
diverse
challenges
due
concerns
about
environment,
human
health,
moral
issues.
Mitigating
scientific
investigations
is
vital.
Hence,
purpose
present
review
discuss
deployment
GM
effects
provides
comprehensive
overview
cultivation
issues
preventing
adoption,
appropriate
strategies
overcome
them.
This
also
presents
recent
tools
genome
editing,
special
focus
CRISPR/Cas9
platform.
An
outline
role
developed
through
CRSIPR/Cas9
achieving
goals
(SDGs)
by
2030
discussed
detail.
Some
perspectives
approval
are
laid
out
age
sustainability.
The
advancement
molecular
plant
editing
addresses
many
facilitates
without
incorporating
transgenic
modifications.
will
allow
higher
acceptance
rate
agriculture
rapid
commercialization.
current
genetic
forecasts
increase
productivity
prosperity
agricultural
practices.
right
use
potential
offer
more
benefit
than
harm,
its
ability
alleviate
crises
around
world.
International Journal of Molecular Sciences,
Год журнала:
2023,
Номер
24(8), С. 7122 - 7122
Опубликована: Апрель 12, 2023
The
biotechnological
approaches
of
transgenesis
and
the
more
recent
eco-friendly
new
breeding
techniques
(NBTs),
in
particular,
genome
editing,
offer
useful
strategies
for
genetic
improvement
crops,
therefore,
recently,
they
have
been
receiving
increasingly
attention.
number
traits
improved
through
editing
technologies
is
growing,
ranging
from
resistance
to
herbicides
insects
capable
coping
with
human
population
growth
climate
change,
such
as
nutritional
quality
or
climatic
stress
diseases.
Research
on
both
has
reached
an
advanced
stage
development
and,
many
biotech
phenotypic
evaluations
open
field
are
already
underway.
In
addition,
approvals
regarding
main
crops
granted.
Over
time,
there
increase
areas
cultivated
that
approaches,
but
their
use
various
countries
limited
by
legislative
restrictions
according
different
regulations
applied
which
affect
cultivation,
marketing,
animal
nutrition.
absence
specific
legislation,
on-going
public
debate
favorable
unfavorable
positions.
This
review
offers
updated
in-depth
discussion
these
issues.
Frontiers in Chemistry,
Год журнала:
2022,
Номер
10
Опубликована: Июль 26, 2022
In
recent
decades,
clustered
regularly
interspaced
short
palindromic
repeat/CRISPR-associated
protein
(CRISPR/Cas)
has
become
one
of
the
most
promising
genome-editing
tools
for
therapeutic
purposes
in
biomedical
and
medical
applications.
Although
CRISPR/Cas
system
truly
revolutionized
era
genome
editing,
safe
effective
delivery
systems
represents
a
substantial
challenge
that
must
be
tackled
to
enable
next
generation
genetic
therapies.
addition,
there
are
some
challenges
vivo
targeted
cells/tissues.
Nanotechnology-based
drug
can
employed
overcome
this
issue.
This
review
discusses
different
types
forms
current
systems,
including
non-viral
carriers
such
as
liposomes,
polymeric,
gold
particles.
The
focus
then
turns
viral
nanocarriers
which
have
been
recently
used
nanocarrier
delivery.
GM crops & food,
Год журнала:
2024,
Номер
15(1), С. 1 - 14
Опубликована: Янв. 12, 2024
This
paper
explores
the
scope
for
newly
emerging
technologies,
based
on
gene
editing
(GE)
contributing
to
addressing
global
challenges
that
we
face.
These
relate
food
security,
climate
change
and
biodiversity
depletion.
In
particular,
it
examines
science
evidence
behind
most
appropriate
forms
of
agricultural
production
meet
these
challenges,
targets
set
in
Global
Biodiversity
Framework
(GBF)
agreed
at
end
2022
possible
role
GE
technologies
meeting
targets.
It
then
risk-appropriate
regulatory
environment
required
best
facilitate
adoption
technology,
drawing
experiences
impact
systems
other
innovations
used
such
as
genetically
modified
organisms
(GMOs).
Frontiers in Genome Editing,
Год журнала:
2022,
Номер
4
Опубликована: Апрель 11, 2022
Innovations
in
food
production
and
processing
have
largely
remained
"behind
the
scenes"
for
decades.
The
current
nature
of
social
media
calls
increased
transparency
regarding
results
a
new
landscape
where
consumer
product
demands
are
more
important
than
ever,
but
increasingly
based
on
limited,
or
incorrect,
information.
One
area
awareness
is
rapidly
emerging
gene-edited
products.
This
article
uses
survey
to
gather
perceptions
safety,
gene
editing
willingness
consume
three
Four
factors
were
found
strongly
influence
perceptions:
trust
Canadian
safety
system;
technology
neophobia
scores;
knowledge
genetics;
self-knowledge
editing.
497
Canadians
that
15%
identified
as
neophobics
12%
neophilics.
majority
participants
neutral.
When
presented
with
various
values,
indicated
nutrition,
price,
taste
most
values.
A
participants'
products
correlated
neophobic
neophilic
preferences,
unwilling
neophilics
being
uncertain.
only
value
affects
environmental
impact
products'
production.
consumers
moderate
high
level
Canada's
system,
this
fails
carry
over
produced
through
innovative
technologies;
however,
express
higher
genetically
modified
technology.
Plants People Planet,
Год журнала:
2023,
Номер
6(1), С. 29 - 43
Опубликована: Июль 22, 2023
Societal
Impact
Statement
A
diverse
portfolio
of
genetically
engineered
food
crops,
as
well
animal
livestock
and
fish,
are
currently
being
developed
commercialized.
To
ensure
their
contributions
to
long‐term
sustainability,
a
broad
range
environmental,
health,
ethical,
societal
parameters
should
be
used
in
evaluations.
This
paper
proposes
set
evaluate
the
sustainability
agriculture
products
discusses
mechanisms
improve
governance
oversight.
With
such
holistic
evaluations,
genetic
engineering
applications
that
deemed
beneficial
sustainable
could
identified
an
effort
foster
sustainability.
Summary
achieve
international
development
goals,
agricultural
production
need
rely
on
resilient
practices.
Traditional
breeding
use
new
technologies,
including
gene
editing,
have
potential
help
agrifood
production.
Although
numerous
oversight
exist
guarantee
secure
advancement
utilization
agrifoods,
majority
these
heavily
depend
narrow
assess
risks
safety
concerning
human
health
nontarget
organisms.
However,
more
comprehensive
considered
promote
environmental
social
manner.
Opinion
article
argues
relies
engineering,
systems
related
biotechnologies
incorporate
broader
array
factors
long‐term.
facilitate
this
process,
we
propose
agrifoods
engineering.
We
then
discuss
major
challenges
opportunities
for
formalizing
US
policy
decision‐making
systems.
Overall,
work
contributes
further
developing
assessment
framework
aims
minimize
maximize
benefits
biotechnology
while
also
fostering
Over
recent
decades,
an
array
of
molecular
tools
has
been
applied
in
plant
genome
engineering,
including
TALENs
(transcription
activator-like
effector
nucleases),
ZFNs
(zinc-finger
and
CRISPR/Cas
systems
(clustered
regularly
interspaced
short
palindromic
repeats).
At
present,
have
caught
significant
industry
attention
owing
to
their
cost-effectiveness
precision
genomic
modulation,
thereby
serving
as
a
potent
tool
science
research.
Importantly,
plants
subjected
editing
via
might
not
be
classified
genetically
modified
organisms
(GMO),
which
could
streamline
acceptance
worldwide.
Originally
discovered
defense
mechanism
against
plasmids
invading
viruses
bacteria
archaea,
the
system
includes
two
components:
CRISPR
ribonucleic
acid
(crRNA)
Cas
protein.
The
crRNA
guides
protein
specific
(DNA)
target
sequence.
Once
there,
cleaves
sequence,
impeding
replication.
In
relation
editing,
researchers
distinct
sequences,
manipulated
function
either
endonuclease
or
base
editor.
most
frequently
used
enzymes
from
Type
II
are
CRISPR/Cas9
CRISPR/Cas12a
(Cpf1).
other
harbor
immense
potential
revolutionize
breeding
biotechnology.
Nevertheless,
use
must
undergo
stringent
regulation
ensure
safe
responsible
application.
future
holds
promise
for
with
safety
being
paramount
concern
crop
gene
editing.
As
such,
it
is
vital
perpetuate
research
development
this
field
fully
exploit
its
advantages
agriculture
because,
technology
advances
new
emerge,
becomes
crucial
governments
keep
abreast
cutting-edge
scientific
progress.
This
awareness
allows
balance
between
benefits
associated
ethical
considerations.
