Genetically engineered crops for sustainably enhanced food production systems

Frontiers in Plant Science, Год журнала: 2022, Номер 13

Опубликована: Ноя. 8, 2022

Genetic modification of crops has substantially focused on improving traits for desirable outcomes. It resulted in the development with enhanced yields, quality, and tolerance to biotic abiotic stresses. With advent introducing favorable into crops, biotechnology created a path involvement genetically modified (GM) sustainable food production systems. Although these plants heralded new era crop production, their widespread adoption faces diverse challenges due concerns about environment, human health, moral issues. Mitigating scientific investigations is vital. Hence, purpose present review discuss deployment GM effects provides comprehensive overview cultivation issues preventing adoption, appropriate strategies overcome them. This also presents recent tools genome editing, special focus CRISPR/Cas9 platform. An outline role developed through CRSIPR/Cas9 achieving goals (SDGs) by 2030 discussed detail. Some perspectives approval are laid out age sustainability. The advancement molecular plant editing addresses many facilitates without incorporating transgenic modifications. will allow higher acceptance rate agriculture rapid commercialization. current genetic forecasts increase productivity prosperity agricultural practices. right use potential offer more benefit than harm, its ability alleviate crises around world.

Язык: Английский

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The function of UDP-glycosyltransferases in plants and their possible use in crop protection

Biotechnology Advances, Год журнала: 2023, Номер 67, С. 108182 - 108182

Опубликована: Июнь 1, 2023

Glycosyltransferases catalyse the transfer of a glycosyl moiety from donor to an acceptor. Members this enzyme class are ubiquitous throughout all kingdoms life and involved in biosynthesis countless types glycosides. Family 1 glycosyltransferases, also referred as uridine diphosphate-dependent glycosyltransferases (UGTs), glycosylate small molecules such secondary metabolites xenobiotics. In plants, UGTs recognised for their multiple functionalities ranging roles growth regulation development, protection against pathogens abiotic stresses adaptation changing environments. study, we review UGT-mediated glycosylation phytohormones, endogenous metabolites, xenobiotics contextualise role chemical modification plays response biotic plant fitness. Here, potential advantages drawbacks altering expression patterns specific along with heterologous across species improve stress tolerance plants discussed. We conclude that UGT-based genetic could potentially enhance agricultural efficiency take part controlling biological activity bioremediation strategies. However, more knowledge intricate interplay between is needed unlock full crop resistance.

Язык: Английский

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The emerging role of nanotechnology in plant genetic engineering

Nature Reviews Bioengineering, Год журнала: 2023, Номер 1(5), С. 314 - 328

Опубликована: Фев. 22, 2023

Язык: Английский

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Factors driving the acceptance of genetically modified food crops in Ghana

Food Safety and Health, Год журнала: 2024, Номер 2(1), С. 158 - 168

Опубликована: Янв. 1, 2024

Abstract Crops produced using recombinant DNA technology have invaluable food security roles but are not broadly accepted. Food insecurity affects between 45% and 50% of the Ghanaian populace, while debate to adopt, accept, use, commercialize genetically modified (GM) crops is ongoing. In this study, a choice‐based conjoint experimental design was adopted investigate factors driving acceptance or rejection GM in Ghana. Results from average marginal component effect estimation suggest that safety concern major driver for accepting rejecting crops. This further confirmed predicted probabilities means community especially when it possesses certain attributes. The safer crop perceived human consumption, health, environment, more likely populace will accept it. addition, yield taste were observed be other key Importantly, country patency also critical factor whether accepted There need active greater engagement with put proper legislation, regulations, policies, knowledge co‐creation process ensure use

Язык: Английский

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Assessment of Benefits and Risk of Genetically Modified Plants and Products: Current Controversies and Perspective

Sustainability, Год журнала: 2023, Номер 15(2), С. 1722 - 1722

Опубликована: Янв. 16, 2023

Genetic transformation has emerged as an important tool for the genetic improvement of valuable plants by incorporating new genes with desirable traits. These strategies are useful especially in crops to increase yields, disease resistance, tolerance environmental stress (cold, heat, drought, salinity, herbicides, and insects) biomass medicinal values plants. The production healthy more products yields can contribute sustainable development goals. introduction genetically modified food into market raised potential risks. A proper assessment their impact on environment biosafety is step before commercialization. In this paper, we summarize discuss risks benefits products, human health hazards transformed plants, effects, Biosafety regulations GMO foods process. mechanisms action those sources, applications healthcare challenges presented. present studies pointed out existence several controversies use GMOs, mainly related health, nutritions, issues. Willingness accept (GM) adoption varies from country country. Knowledge about gene engineering technology, debate between government agencies, scientist, environmentalist NGOs GM major factors low adoptions regulation. Therefore, will help advancement plant species future; however, research detailed required.

Язык: Английский

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Immortalized Bovine Satellite Cells for Cultured Meat Applications

ACS Synthetic Biology, Год журнала: 2023, Номер 12(5), С. 1567 - 1573

Опубликована: Май 5, 2023

For cultured meat to succeed at scale, muscle cells from food-relevant species must be expanded in vitro a rapid and reliable manner produce millions of metric tons biomass annually. Toward this goal, genetically immortalized offer substantial benefits over primary cells, including growth, escape cellular senescence, consistent starting cell populations for production. Here, we develop bovine satellite (iBSCs) via constitutive expression Telomerase reverse transcriptase (TERT) Cyclin-dependent kinase 4 (CDK4). These achieve 120 doublings the time publication maintain their capacity myogenic differentiation. They therefore valuable tool field, enabling further research development advance meat.

Язык: Английский

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A Critical Review: Recent Advancements in the Use of CRISPR/Cas9 Technology to Enhance Crops and Alleviate Global Food Crises

Current Issues in Molecular Biology, Год журнала: 2021, Номер 43(3), С. 1950 - 1976

Опубликована: Ноя. 11, 2021

Genome editing (GE) has revolutionized the biological sciences by creating a novel approach for manipulating genomes of living organisms. Many tools have been developed in recent years to enable complex genomes. Therefore, reliable and rapid increasing yield tolerance various environmental stresses is necessary sustain agricultural crop production global food security. This critical review elaborates GE used improvement. These include mega-nucleases (MNs), such as zinc-finger nucleases (ZFNs), transcriptional activator-like effector (TALENs), clustered regularly interspaced short palindromic repeats (CRISPR). Specifically, this addresses latest advancements role CRISPR/Cas9 genome manipulation major improvement, including quality development biotic stress- abiotic stress-tolerant crops. Implementation technique will lead non-transgene crops with preferred characteristics that can result enhanced capacity under stresses. The be combined current potential breeding methods (e.g., speed omics-assisted breeding) enhance productivity ensure We also discussed challenges limitations CRISPR/Cas9. information useful plant breeders researchers thorough investigation use boost targeting gene interest.

Язык: Английский

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Food safety hazards of bee pollen – A review

Trends in Food Science & Technology, Год журнала: 2021, Номер 114, С. 490 - 509

Опубликована: Июнь 12, 2021

Bee pollen is a natural apicultural product that becoming popular among health-conscious consumers due to its wide variety of nutrients and bioactive substances. However, only limited number countries have established requirements for the quality safety so far. In this review, recent findings on food risks bee data about concentration toxic substances detected in products are summarized. Pollen loads may become contaminated from environment with pesticides, heavy metals, metalloids mycotoxin-producing molds. addition, certain plant species initially contain hepatotoxic pyrrolizidine alkaloids relatively large concentrations. Allergens grains genetically modified plants also be present these products. Based literature data, risk assessment was conducted most common pesticide active (chlorpyrifos, fluvalinate, carbendazim, thiacloprid), toxicologically important elements (arsenic, cadmium, mercury, lead), mycotoxins (aflatoxin-B1, ochratoxin-A, fumonisins, zearalenone, deoxynivalenol, T-2 toxin) alkaloids. Key Findings Conclusions: Our results suggest residues usually do not pose chronic consumers, but estimated acute exposure values can close reference dose (ARfD). Arsenic, lead alkaloid content potentially health therefore it recommended set maximum limit monitor their commercially available Since scientific regarding mercury mycotoxin incomplete, further studies needed order summarize hazards pollutants.

Язык: Английский

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Challenges Facing CRISPR/Cas9-Based Genome Editing in Plants

Frontiers in Plant Science, Год журнала: 2022, Номер 13

Опубликована: Май 18, 2022

The development of plant varieties with desired traits is imperative to ensure future food security. revolution genome editing technologies based on the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated nuclease 9 (Cas9) system has ushered in a new era breeding. Cas9 and single-guide RNA (sgRNA) form an effective targeting complex locus or loci interest, enabling all plants high accuracy efficiency. Therefore, CRISPR/Cas9 can save both time labor relative what typically associated traditional breeding methods. However, despite improvements gene editing, several challenges remain that limit application CRISPR/Cas9-based plants. Here, we focus four issues relevant editing: (1) organelle editing; (2) transgene-free (3) virus-induced (4) recalcitrant elite crop inbred lines. This review provides up-to-date summary state CRISPR/Cas9-mediated will push this technique forward.

Язык: Английский

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An Outlook on Global Regulatory Landscape for Genome-Edited Crops

International Journal of Molecular Sciences, Год журнала: 2021, Номер 22(21), С. 11753 - 11753

Опубликована: Окт. 29, 2021

The revolutionary technology of CRISPR/Cas systems and their extraordinary potential to address fundamental questions in every field biological sciences has led developers being awarded the 2020 Nobel Prize for Chemistry. In agriculture, have accelerated development new crop varieties with improved traits—without need transgenes. However, future this depends on a clear truly global regulatory framework developed these crops. Some CRISPR-edited crops are already market, yet countries regions still divided over legal status. CRISPR editing does not require transgenes, making more socially acceptable than genetically modified crops, but there is vigorous debate how regulate what precautionary measures required before they appear market. This article reviews intended outcomes risks arising from site-directed nuclease used improve agricultural plant genomes. It examines various system components, concerns associated CRISPR/Cas, may trigger oversight highlights differences similarities between GMOs discusses social ethical concerns. outlines GMO which many also apply landscape concludes prospects products.

Язык: Английский

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