Production of Bioactive Phytochemicals from Ethnomedicinal Plant Endophytic Microorganisms DOI Creative Commons

Jacqueline Makatiani,

Elijah Kipkorir Lelmen

Biochemistry, Год журнала: 2024, Номер unknown

Опубликована: Окт. 21, 2024

Ethnomedicinal plants are extensively explored for the discovery of new bioactive phytochemicals with applications in agrochemical, food and pharmaceutical industries. This could lead to extinction some endangered plant species, hence need phytochemical production strategies. Medicinal plant-associated microbial endophytes act as a promising eco-friendly source high-valued phytochemicals. Numerous reports have focused on bioprospecting novel or existing biomolecules. However, investigations techniques high-value-low volume secondary metabolites extremely limited. Moreover, exploration bacterial actinomycete sources has not been fully elucidated. chapter highlights diversity, distribution, bioactivity ethnomedicinal isolated between 2014 2024. Additionally, recent advances biotechnological strain improvement such genome editing enhanced vitro discussed.

Язык: Английский

Impact of Heavy Metal Pollution in the Environment on the Metabolic Profile of Medicinal Plants and Their Therapeutic Potential DOI Creative Commons

Dana-Mihaela Asiminicesei,

Daniela Ionela Ferţu, Maria Gavrilescu

и другие.

Plants, Год журнала: 2024, Номер 13(6), С. 913 - 913

Опубликована: Март 21, 2024

The paper provides a comprehensive examination of heavy metal stress on medicinal plants, focusing its impact antioxidant capacity and biosynthetic pathways critical to their therapeutic potential. It explores the complex relationship between metals physiological biochemical responses highlighting how disrupts pathways, altering concentrations secondary metabolites. This disruption may compromise overall quality efficacy requiring holistic understanding cumulative impacts. Furthermore, study discusses potential targeted genetic editing enhance plant resilience against by manipulating genes associated with defenses. approach represents promising frontier in safeguarding plants metal-contaminated environments. Additionally, research investigates role phytohormone signaling adaptive mechanisms stress, revealing influence responses, thereby adding complexity adaptation. underscores importance innovative technologies global cooperation protecting plants’ highlights need for mitigation strategies address contamination effectively.

Язык: Английский

Процитировано

31

Environmental factors on secondary metabolism in medicinal plants: exploring accelerating factors DOI Creative Commons
Mohammad Murtaza Alami,

S. Guo,

Zhinan Mei

и другие.

Medicinal Plant Biology, Год журнала: 2024, Номер 3(1), С. 0 - 0

Опубликована: Янв. 1, 2024

Medicinal plants are vital in synthesizing crucial substrates, fortifying stress resilience, and serving clinical industrial domains. The optimization of pharmacological potential necessitates a nuanced understanding the factors governing synthesis secondary metabolites sourced from plants. Cultivation success hinges upon many dictating production these compounds. Biotic factors, encompassing pathogens herbivores, alongside abiotic such as light exposure, altitude, temperature variations, irrigation patterns, soil fertility, drought susceptibility, salinity levels, collectively orchestrate medicinal plants' growth, development, metabolic pathways. This comprehensive review delves into intricate interplay influencing formation metabolites, exploring roles endophytes, pathogens, availability, fluctuations, stress, pollution impacts, plant growth regulators. Grasping dynamics is imperative for devising strategic interventions to enhance metabolite production, thereby ensuring sustainable efficient cultivation

Язык: Английский

Процитировано

10

Phyllanthus Lignans: A Review of Biological Activity and Elicitation DOI Creative Commons
Winda Nawfetrias,

Lukita Devy,

Rizkita Rachmi Esyanti

и другие.

Horticulturae, Год журнала: 2024, Номер 10(2), С. 195 - 195

Опубликована: Фев. 19, 2024

The Phyllanthus genus exhibits a broad distribution spanning across the majority of tropical and subtropical regions. Due to their ability synthesize medicinal bioactive compounds such as lignans, they have been utilized historically in traditional medicine treat wide range ailments. This review discusses current knowledge on potency lignans for purposes, benefit plants, various produced by Phyllanthus, how lignan synthesis could be increased through biotic abiotic elicitation. Finally, we present set connected hypotheses explain signaling crosstalk between endophytic microbes drought stress responses regulates production. Although mechanisms are not fully explored, this strongly supports view that fungi can increase production plants belonging Phyllanthus. plant–endophyte–drought relationship helps improve yield which is crucial human health optimized under vitro vivo conditions.

Язык: Английский

Процитировано

5

Deciphering the endomicrobiome of Podophyllum hexandrum to reveal the endophytic bacterial-association of in-planta podophyllotoxin biosynthesis DOI
Meena Kumari, Anish Tamang, Mohit Kumar Swarnkar

и другие.

World Journal of Microbiology and Biotechnology, Год журнала: 2025, Номер 41(2)

Опубликована: Янв. 16, 2025

Язык: Английский

Процитировано

0

Seed bacterization with siderophore-producing bacteria: a strategy to enhance growth and alkaloid content in Catharanthus roseus DOI Creative Commons
Vyoma Mistry,

Sapna Chandwani,

Natarajan Amaresan

и другие.

World Journal of Microbiology and Biotechnology, Год журнала: 2025, Номер 41(2)

Опубликована: Янв. 20, 2025

Язык: Английский

Процитировано

0

Marine fungi as a goldmine for novel antibiotics: a 2024 perspective DOI Creative Commons
Chengqian Pan,

Syed Shams ul Hassan,

Ishaq Muhammad

и другие.

Frontiers in Marine Science, Год журнала: 2025, Номер 11

Опубликована: Янв. 21, 2025

The microbial diversity in oceans is considerable, widely distributed seawater, marine sediments, and organisms. Compared with terrestrial resources traditional natural product research, the living environments of microorganisms are starkly different. drastic differences survival conditions, such as high salinity, oligotrophic lack light, limited oxygen, determine that exhibit distinctive characteristics metabolism, modes, adaptive mechanisms. These factors contribute to significant distinctions secondary metabolic pathways enzymatic reaction mechanisms between microorganisms. In this review, we summarized a total 72 novel products antibacterial activity, published 2024, which derived from marine-derived fungi. (polyketides, alkaloids, terpenoids, peptides) emphasized terms their structures biological activities. This article aims provide useful information for research development antibiotics.

Язык: Английский

Процитировано

0

Phytohormone Production by Endophytic Fungi DOI

Hajira Younas,

Fatima Younas

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0

Mass spectrometric profile, antioxidant and oral pathogen biofilm control capacity of small molecules from an endophyte Cladospoium species: in vitro and in silico models DOI Creative Commons

A. P. Manasa,

Deena Mendez,

P Kiranmayee

и другие.

The Microbe, Год журнала: 2025, Номер unknown, С. 100267 - 100267

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

0

Occurrence and characterization of fungal species in medicinal plants from South Africa DOI Creative Commons

Oluwaseun Mary Oladeji,

Judith Zanele Phoku,

Oluwasola Abayomi Adelusi

и другие.

Discover Life, Год журнала: 2025, Номер 55(1)

Опубликована: Фев. 21, 2025

Язык: Английский

Процитировано

0

Endophytic fungi and age-related diseases: Potential for geriatric therapeutics DOI
Rachan Karmakar,

Sunil Kumar,

Vijay Tripathi

и другие.

Elsevier eBooks, Год журнала: 2025, Номер unknown, С. 295 - 313

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0