Subthreshold Depression: A Systematic Review and Network Meta-Analysis of Non-Pharmacological Interventions DOI Creative Commons
Xiaofei Hao,

Yuying Jia,

Jie Chen

и другие.

Neuropsychiatric Disease and Treatment, Год журнала: 2023, Номер Volume 19, С. 2149 - 2169

Опубликована: Окт. 1, 2023

Background: Subthreshold depression (StD) is considered to be the "precursor" stage of major depressive disorder (MDD), which could cause higher risk suicide, disease burden and functional impairment. There have been various non-pharmacological interventions for StD. However, comparison their effectiveness still lacks sufficient evidence. We performed a systematic review network meta-analysis evaluate rank efficacy multiple targeting Methods: conducted thorough search across databases including PubMed, Medline, Embase, Web Science PsycINFO from inception December 2022. All included studies were randomized controlled trials (RCTs) patients with StD compared control group (CG). Several universal scales measuring severity used as outcomes. The surface under cumulative ranking curve (SUCRA) was separately each intervention using "Stata 17.0" software. Results: A total thirty-six included, involving twenty-eight 7417 participants. research found that most superior controls In outcome evaluation by different depression, psychotherapy always ranked first in terms treatment effectiveness, especially Problem-solving Therapy (PST), Behavioral Activation (BAT), Cognitive (CBT)/Internet-based CBT (I-CBT)/Telephone-based (T-CBT). Since groups not directly compared, optimal determined. Conclusion: Here, we show may better choice This study provides some evidence on management selection clinical workers. establish its effect more conclusively, content, format operators require extensive exploration conduct effective, convenient cost-effective implementation primary healthcare. Notably, further also urgently needed find biological neural mechanisms examining whether alters neuroplasticity Keywords: subthreshold intervention, efficacy, comparison, meta-analysis,

Язык: Английский

Activated Tryptophan-Kynurenine metabolic system in the human brain is associated with learned fear DOI Creative Commons

Maria Rita Battaglia,

Chiara Di Fazio, Simone Battaglia

и другие.

Frontiers in Molecular Neuroscience, Год журнала: 2023, Номер 16

Опубликована: Июль 28, 2023

OPINION article Front. Mol. Neurosci., 28 July 2023Sec. Molecular Signalling and Pathways Volume 16 - 2023 | https://doi.org/10.3389/fnmol.2023.1217090

Язык: Английский

Процитировано

42

Neural Correlates and Molecular Mechanisms of Memory and Learning DOI Open Access
Simone Battaglia, Alessio Avenanti, László Vécsei

и другие.

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(5), С. 2724 - 2724

Опубликована: Фев. 27, 2024

Memory and learning are essential cognitive processes that enable us to obtain, retain, recall information [...].

Язык: Английский

Процитировано

33

Neurodegeneration in Cognitive Impairment and Mood Disorders for Experimental, Clinical and Translational Neuropsychiatry DOI Creative Commons
Simone Battaglia, Alessio Avenanti, László Vécsei

и другие.

Biomedicines, Год журнала: 2024, Номер 12(3), С. 574 - 574

Опубликована: Март 5, 2024

Neurodegeneration poses a significant challenge for the fields of neuroscience and medicine, as it is underlying cause development advancement numerous neurodegenerative psychiatric disorders [...]

Язык: Английский

Процитировано

25

Error-related cardiac deceleration: Functional interplay between error-related brain activity and autonomic nervous system in performance monitoring DOI Creative Commons
Francesco Di Gregorio, Marco Steinhauser, Martin E. Maier

и другие.

Neuroscience & Biobehavioral Reviews, Год журнала: 2024, Номер 157, С. 105542 - 105542

Опубликована: Янв. 11, 2024

Coordinated interactions between the central and autonomic nervous systems are crucial for survival due to inherent propensity human behavior make errors. In our ever-changing environment, when individuals mistakes, these errors can have life-threatening consequences. response errors, specific reactions occur in both brain activity heart rate detect correct Specifically, there two brain-related indicators of error detection awareness known as error-related negativity positivity. Conversely, cardiac deceleration denotes a momentary slowing following an error, signaling response. However, what is connection during processing? this review, we discuss functional neuroanatomical connections markers processing, exploring experimental conditions which they covary. Given current limitations available data, future research will continue investigate neurobiological factors governing brain-heart interaction, aiming utilize them combined assessing cognitive control healthy pathological conditions.

Язык: Английский

Процитировано

24

The Orexin/Hypocretin System, the Peptidergic Regulator of Vigilance, Orchestrates Adaptation to Stress DOI Creative Commons
Miklós Jászberényi,

Balázs Thurzó,

Zsolt Bagosi

и другие.

Biomedicines, Год журнала: 2024, Номер 12(2), С. 448 - 448

Опубликована: Фев. 17, 2024

The orexin/hypocretin neuropeptide family has emerged as a focal point of neuroscientific research following the discovery that this plays crucial role in variety physiological and behavioral processes. These neuropeptides serve powerful neuromodulators, intricately shaping autonomic, endocrine, responses across species. Notably, they master regulators vigilance stress responses; however, their roles food intake, metabolism, thermoregulation appear complementary warrant further investigation. This narrative review provides journey through evolution our understanding orexin system, from its initial to promising progress made developing derivatives. It goes beyond conventional boundaries, striving synthesize multifaceted activities orexins. Special emphasis is placed on domains such response, fear, anxiety, learning, which authors have contributed literature with original publications. paper also overviews advancement pharmacology, already yielded some successes, particularly treatment sleep disorders.

Язык: Английский

Процитировано

22

The intricate brain–body interaction in psychiatric and neurological diseases DOI Creative Commons
Francesco Di Gregorio, Simone Battaglia

Advances in Clinical and Experimental Medicine, Год журнала: 2024, Номер 33(4), С. 321 - 326

Опубликована: Март 21, 2024

A harmonic brain-body communication is fundamental to individual wellbeing and the basis of human cognition behavior.In last 2 decades, interaction between brain body functioning has become a central area study for neurologists neuroscientists in clinical non-clinical contexts.Indeed, axis dysfunctions occur many psychiatric, neurological neurodegenerative diseases.This editorial will focus on recent advances future therapeutic perspectives studying interactions health diseases.

Язык: Английский

Процитировано

22

From Lab to Life: Exploring Cutting-Edge Models for Neurological and Psychiatric Disorders DOI Creative Commons
Masaru Tanaka, László Vécsei

Biomedicines, Год журнала: 2024, Номер 12(3), С. 613 - 613

Опубликована: Март 8, 2024

Neuroscience, neurology, and psychiatry are rapidly evolving fields that aim to understand the complex mechanisms underlying brain function dysfunction, as well develop effective interventions for various neurological psychiatric disorders [...]

Язык: Английский

Процитировано

19

Innovation at the Intersection: Emerging Translational Research in Neurology and Psychiatry DOI Creative Commons
Masaru Tanaka, Simone Battaglia, Lydia Giménez‐Llort

и другие.

Cells, Год журнала: 2024, Номер 13(10), С. 790 - 790

Опубликована: Май 7, 2024

Translational research in neurological and psychiatric diseases is a rapidly advancing field that promises to redefine our approach these complex conditions [...]

Язык: Английский

Процитировано

19

Innovation at the Intersection: Emerging Translational Research in Neurology and Psychiatry DOI Open Access
Masaru Tanaka, Simone Battaglia, Lydia Giménez‐Llort

и другие.

Опубликована: Апрель 17, 2024

The editorial explores the realm of emerging translational research in neurology and psychiatry, providing insights into various subjects, including neurodegenerative disorders innovative therapeutic methods. main objective is to study neurological psychiatric disorders, such as Alzheimer's disease, with a particular emphasis on techniques for neural regeneration repair. highlights importance taking comprehensive approach studying treating complex conditions. This involves thoroughly reviewing papers causes, development, biomarkers, treatment options these emphasizes necessity using multidisciplinary integrative methods gain deeper understanding improve development an animal model recurrent primary dysmenorrhea showcases employed investigation gynecological illustrating capacity connect fundamental scientific knowledge practical medical applications. cooperative endeavors researchers clinicians emphasized this lay foundation revolutionary advancements that hold potential enhance outcomes individuals afflicted globally.

Язык: Английский

Процитировано

17

A Decade of Dedication: Pioneering Perspectives on Neurological Diseases and Mental Illnesses DOI Creative Commons
Masaru Tanaka, László Vécsei

Biomedicines, Год журнала: 2024, Номер 12(5), С. 1083 - 1083

Опубликована: Май 13, 2024

Welcome to

Язык: Английский

Процитировано

17