Dissecting the rising tide of inflammatory bowel disease among youth in a changing world: insights from GBD 2021 DOI Creative Commons
He Zhang, Yang Xu,

Feiyan Ai

и другие.

International Journal of Colorectal Disease, Год журнала: 2025, Номер 40(1)

Опубликована: Фев. 18, 2025

This study investigates the alarming epidemiological trends of inflammatory bowel disease (IBD) among children and young adults, highlighting associated burden on global health. Utilizing data from Global Burden Disease (GBD) 2021, we conducted a comprehensive analysis age-standardized incidence rates (ASIR), mortality (ASMR), disability-adjusted life years (DALYs), estimated annual percentage changes (EAPC). Future were forecasted using Bayesian age-period-cohort model. From 1990 to IBD DALY remained persistently high, with concerning upward trend noted adults. While men experienced decline in rates, women faced increasing burdens. In high-income regions, particularly North America, reported highest contrasting sharply Central Latin which exhibited lowest ASIR. Southeast Asia presented most favorable rates. A notable negative correlation was identified between socio-demographic index (SDI) at national level, high high-middle SDI countries continuing bear substantial burden, while low middle nations rising challenges. The persistent adults signifies critical public health concern. marked geographical gender disparities underscore urgent need for tailored regional population-based strategies aimed primary prevention effective management. illuminates pressing necessity policy interventions address growing epidemic vulnerable populations.

Язык: Английский

The trends of lung cancer burden in BRICS from 1990 to 2021 and its projection to 2035 DOI Creative Commons
Yifan Wang,

Jingwen Zhu,

Shaoqiang Wang

и другие.

Frontiers in Oncology, Год журнала: 2025, Номер 14

Опубликована: Янв. 3, 2025

Lung cancer has become the malignant tumor with highest morbidity and mortality in world. This study aims to analyze burden of lung risk factors associated BRICS from 1990-2021 project 2021-2035. The Global Burden Disease (GBD) 2021 database was searched collect incidence, prevalence, mortality, disability-adjusted life years (DALYs), BRICS. Trends were analyzed using Joinpoint 4.9.1.0, Bayesian age-period-cohort (BAPC) analyses performed R4.4.1 disease AAPC(average annual percentage change) EAPC(estimated average ASIR(age-standardized incidence), ASPR(age-standardized prevalence), ASMR(age-standardized mortality), ASDR(age-standardized year) for Brazil, Russia, Ethiopia less than 0. Egypt's AAPC EAPC ASIR, ASPR, ASMR, ASDR all greater 0 1990-2021, China's at top 2021. According BAPC projection Iran, South Africa will have a decreasing trend Egypt an increasing With exception Ethiopia, tier level 1 2 rest behavioral smoking factors, respectively. still heavy cancer, there are significant differences among At same time, many prevention control measures worth learning other developing countries.

Язык: Английский

Процитировано

0
Long-term trends in the burden of pulmonary arterial hypertension in China and worldwide: new insights based on GBD 2021 DOI Creative Commons

Zhehao Xu,

Jia Ding,

Ruixin Liang

и другие.

Frontiers in Medicine, Год журнала: 2025, Номер 11

Опубликована: Янв. 7, 2025

Pulmonary arterial hypertension (PAH) poses a significant health challenge globally, with China experiencing notable increase in its burden. Understanding the trends and factors contributing to PAH is crucial for developing effective public strategies. This study utilized data from Global Burden of Disease (GBD) 2021 database estimate burden worldwide 1990 2021. A Bayesian age-period-cohort (BAPC) model was employed analyze differences across age, gender, time periods, project global epidemiological until 2036. From 2021, incidence prevalence increased by 80.59% 86.74%, respectively. The age-standardized rate (ASIR) (ASPR) showed an annual percentage change (AAPC) -0.07% 0.25%, Conversely, disability-adjusted life year (DALY) mortality (ASMR) have been declining since 1990, AAPC -1.90% -1.26%, Females 50-70 years age group experienced higher compared males. Projections indicate that ASPR, ASMR, death (ASDR) will stabilize minimal variation over next decade. findings highlight age-related China, particularly affecting older populations women. projected stabilization metrics decade underscores need continued monitoring targeted interventions. study's comprehensive analysis three decades provides valuable insights policymakers healthcare providers, necessitating concerted efforts address this critical issue.

Язык: Английский

Процитировано

0
Tuberculosis disease burden in China: a spatio-temporal clustering and prediction study DOI Creative Commons

Jingzhe Guo,

Ce Liu, Fang Liu

и другие.

Frontiers in Public Health, Год журнала: 2025, Номер 12

Опубликована: Янв. 7, 2025

The primary aim of this study is to investigate and predict the prevalence determinants tuberculosis disease burden in China. Leveraging high-quality data sources employing a methodologically rigorous approach, endeavors enhance our understanding control efforts across different regions First, through nationwide spatio-temporal cluster analysis, we summarized status various China explore differences, thereby providing basis for formulating more targeted prevention policies regions; Subsequently, using time series-based forecasting model, conducted first-ever national trend forecast offer scientific guidance timely adjustments planning resource allocation. This research seeks contribute significantly China's existing system. draws upon publicly available pulmonary (PTB) incidence mortality statistics from 31 provinces municipalities mainland between 2004 2018. We organized classified these according province, month, year, patient age group. Overall, sample included 14,816,329 new instances PTB 42,465 PTB-related fatalities. used spatiotemporal analysis record epidemiological characteristics patterns during period. Additionally, series model was constructed analyze trends reveals significant regional variations Tibet (124.24%) Xinjiang (114.72%) western exhibited largest percentage change (TB) incidence, while Zhejiang Province (-50.45%) Jiangsu (-51.33%) eastern showed decreases. Regions with increases rates (>100%) four regions, six central five regions. relatively large decreases rate include Tianjin (-52.25%) Shanghai (-68.30%). These differences are attributed two main factors: (1) economic imbalances leading poor TB underdeveloped areas, (2) TB-related among causing uneven distribution risks. Consequently, may still face challenges achieving World Health Organization's 2030 goals. Nationwide, increased 2018 (percentage change: 105.35%, AAPC: 4.1), downward -20.59%, -2.1). Among groups, 0-19 group has smallest burden. While were primarily found adults 60 years or older, TB, highlighting obvious characteristics. It predicted that will continue increase. In summary, epidemic been largely controlled due implementation many public health programs targeting specific groups geographical areas. Finding supporting effective make it possible achieve goal controlling

Язык: Английский

Процитировано

0
The global prevalence of complete hearing loss in 204 countries and territories from 1992 to 2021: a systematic analysis for the global burden of disease study 2021 DOI Creative Commons
Guan‐Jiang Huang,

Zhi‐Jun Fan,

Biao-Qing Lu

и другие.

Frontiers in Public Health, Год журнала: 2025, Номер 13

Опубликована: Апрель 9, 2025

Complete hearing loss, especially the age-related type, poses a significant public health challenge globally. This study aims to assess global burden on prevalence of complete loss from 1992 2021 and forecast trends up 2036. Using data Global Burden Disease (GBD) Study 2021, we assessed across 204 countries territories. We analyzed temporal in ASPR using Joinpoint regression, evaluated contributions age, period, cohort effects through Age-Period-Cohort modeling, performed decomposition analysis determine impact demographic epidemiological changes trends. Predictions future were made Bayesian (BAPC) Autoregressive Integrated Moving Average (ARIMA) models. By had reached 9.9 million cases, with declining 134.35 117.79 per 100,000. The overall Estimated Annual Percentage Change (EAPC) was-0.45. most reductions observed low-SDI regions, particularly Sub-Saharan Africa (EAPC: -0.74). In contrast, high-SDI including North America Western Europe, showed more modest declines -0.18). Notably, East Asia exhibited 62.3% increase prevalence, high-income Pacific showing highest relative rise at 83.97%. Age-related remained dominant cause, among individuals aged 60 above. Males affected than females. Population aging growth major drivers increased while population was primary factor areas. remains high populations within despite ASPR. Significant regional disparities remain, highlighting need for targeted interventions improve access care affordable technologies regions.

Язык: Английский

Процитировано

0
An analysis of trends in the burden of ischemic stroke caused by air pollution in China between 1990 and 2021 DOI Creative Commons

Zhengfeng Yu,

Xiuyun Zhang,

Xiaomei Fu

и другие.

BMC Public Health, Год журнала: 2025, Номер 25(1)

Опубликована: Апрель 28, 2025

This study evaluates the burden of ischemic stroke attributable to air pollution in China from 1990 2021, examines gender and age-specific differences, projects future disease trends 2022 2036. By analyzing impact on stroke, this aims provide insights for public health policies preventive measures. Utilizing data 2021 Global Burden Disease (GBD) study, research examined associated with China. To assess historical project 2036, Joinpoint regression modeling decomposition analysis were employed. These methods allow identifying significant trend changes disentangling contributions various factors. From observed a decline both age-standardized mortality rates (ASMR) disability-adjusted life years (DALY) attributed pollution. However, was slower among men than women, higher elderly males. Epidemiological transitions, including improved healthcare lifestyle changes, main drivers behind overall reduction burden. Projections indicate that over next 15 years, ASMR DALY (ASDR) women will continue decline, while is expected rise ASDR gradually increase before stabilizing. Elderly males are disproportionately affected by related pollution, highlighting critical issue. mitigate burden, it essential government implement targeted, gender- aimed at improving quality, enhancing access, promoting measures vulnerable populations, particularly men. findings underscore need integrated strategies reduce disparities address ongoing challenges posed

Язык: Английский

Процитировано

0
Analysis of trends in the burden of colorectal cancer in China and globally from 1990 to 2021 with projections for the next 15 years: a cross-sectional study based on the GBD database DOI Creative Commons
Yulai Yin,

Xiaoyu Zhang

Frontiers in Public Health, Год журнала: 2025, Номер 13

Опубликована: Май 26, 2025

Objective To analyze the changes in burden of colorectal cancer China and globally from 1990 to 2021, explore disease across different age groups sexes by integrating projected data 2022 2036. This study aims provide a scientific foundation for formulating targeted prevention control strategies. Materials methods utilized Global Burden Disease (GBD) database period 1990–2021. Trend analysis was conducted using Joinpoint regression, future projections 2036 were made with an Auto-Regressive Integrated Moving Average (ARIMA) model. Key indicators analyzed included Age-Standardized Incidence Rate (ASIR), Prevalence (ASPR), Mortality (ASMR), Disability-Adjusted Life Years (DALYs). Results Between increased both globally, although notable differences observed gender regions. In Chinese men, ASIR ASMR have shown continuous rise, reaching approximately 50 300 per 100,000, respectively, 2021. Projections indicate that these rates will continue increase through at least The women also exhibits upward trend, whereas global has declined. From world experienced steady rise ASPR, minimal fluctuations. contrast, while ASDR decreased volatility China’s is notably more pronounced than worldwide. Conclusion significantly coming years, particularly among males older adult population. provides critical insights development strategies resource allocation, underscoring urgent need enhance early screening initiatives health education efforts China.

Язык: Английский

Процитировано

0
Global, regional, and national burden of intestinal obstruction from 1990 to 2019: an analysis from the Global Burden of Disease Study 2019 DOI

Dan Long,

Chenhan Mao, Yaxuan Liu

и другие.

International Journal of Colorectal Disease, Год журнала: 2023, Номер 38(1)

Опубликована: Окт. 3, 2023

Язык: Английский

Процитировано

9
Comparison of the burden of digestive diseases between China and the United States from 1990 to 2019 DOI Creative Commons

Jieyu Peng,

Huan Xu,

Shu Huang

и другие.

Frontiers in Public Health, Год журнала: 2024, Номер 12

Опубликована: Май 17, 2024

Introduction China has experienced unprecedented transformations unseen in a century and is gradually progressing toward an emerging superpower. The epidemiological trends of digestive diseases the United States (the US) have significant prescient effects on China. Methods We extracted data 18 from Global Burden Diseases 2019 Data Resource. Linear regression analysis conducted by JoinPoint software assessed average annual percentage change burden. performed subgroup analyses based sex age group. Results In 2019, there were 836.01 180.91 million new cases US, causing 1558.01 339.54 thousand deaths. age-standardized incidence rates US 58417.87/100,000 55018.65/100,000 respectively, resulting mortality 81.52/100,000 60.88/100,000. annually decreased 2.149% for 2.611% disability-adjusted life year (DALY). DALY had changes −0.219 −0.251. Enteric infections cirrhosis other chronic liver accounted highest prevalence both counties, respectively. burden multiple exhibited notable disparities. middle-old persons higher rates. Conclusion bore greater diseases, evolving patterns more noticeable. Targeted interventions urgent measures should be taken countries to address specific their different epidemic degree.

Язык: Английский

Процитировано

3
Association of diet and outdoor time with inflammatory bowel disease: a multicenter case-control study using propensity matching analysis in China DOI Creative Commons

Xiaotian Chu,

Xuanfu Chen,

Huimin Zhang

и другие.

Frontiers in Public Health, Год журнала: 2024, Номер 12

Опубликована: Июнь 17, 2024

Objective To investigate the association between dietary and some other environmental factors risk of inflammatory bowel diseases (IBD) in Chinese population. Materials methods A multicenter case-control study was conducted involving 11 hospitals across China. total 1,230 subjects were enrolled consecutively, diet factor questionnaires collected. IBD patients matched with healthy controls (HC) using propensity-score matching (PSM) at a 1:1 ratio caliper value 0.02. Multivariate conditional logistic regression analyses performed to evaluate associations diet, factors, IBD. Results Moderate alcohol milk consumption, as well daily intake fresh fruit, protective for both Crohn's disease (CD) ulcerative colitis (UC). Conversely, consumption eggs chocolate increased Outdoor time more than 25% day only CD. In eastern regions China, CD had higher egg less outdoor time, while UC consumed chocolate. from urban areas or per capita monthly income eggs, Conclusions This reveals an specific foods, emergence The findings emphasize importance balanced sufficient activities, tailored prevention strategies considering regional variations.

Язык: Английский

Процитировано

3
The Burden of Severe Periodontitis in China From 1990 to 2021, With Projections to 2050: A Comprehensive Analysis From The Global Burden of Disease Study 2021 DOI Creative Commons
Yuyang Wang,

Yinbao Wang,

Lu Fan

и другие.

International Dental Journal, Год журнала: 2024, Номер unknown

Опубликована: Дек. 1, 2024

Язык: Английский

Процитировано

3