Neurochemical Journal, Год журнала: 2024, Номер 18(4), С. 603 - 616
Опубликована: Дек. 1, 2024
Язык: Английский
World Journal of Hepatology, Год журнала: 2024, Номер 16(6), С. 951 - 965
Опубликована: Июнь 19, 2024
BACKGROUND Nonalcoholic fatty liver disease (NAFLD) is a condition that prevalent worldwide and associated with significant health risks economic burdens. As it has been linked to insulin resistance (IR), this study aimed perform bibliometric analysis visually represent the scientific literature on IR NAFLD. AIM To map research landscape underscore critical areas of focus, influential studies, future directions NAFLD IR. METHODS This conducted indexed in SciVerse Scopus database from 1999 2022. The search strategy used terms medical subject headings, focusing related VOSviewer software was visualize trends, collaborations, key thematic areas. examined publication type, annual output, contributing countries institutions, funding agencies, journal impact factors, citation patterns, highly cited references. RESULTS identified 23124 documents NAFLD, revealing increase number publications between retrieved 715 papers including 573 (80.14%) articles 88 (12.31%) reviews. most productive were China (n = 134; 18.74%), United States 122; 17.06%), Italy 97; 13.57%), Japan 41; 5.73%). leading institutions included Università degli Studi di Torino, 29; 4.06%), Consiglio Nazionale delle Ricerche, 19; 2.66%). top agencies National Institute Diabetes Digestive Kidney Diseases 48; 6.71%), Natural Science Foundation 37; 5.17%). active journals field Hepatology (27 publications), Journal (17 Clinical Endocrinology Metabolism (13 publications). main hotspots “therapeutic approaches for NAFLD” “inflammatory high-fat diet impacts NAFLD”. CONCLUSION first examine relationship In response escalating global challenge highlights an urgent need better understanding development intervention strategies. Policymakers prioritize address increasing prevalence
Язык: Английский
Процитировано
1
Medicine, Год журнала: 2024, Номер 103(28), С. e38831 - e38831
Опубликована: Июль 12, 2024
Cirrhosis is a chronic liver disease with severe consequences for patient’s health and survival. Exercise an essential therapeutic strategy both cirrhosis prevention treatment. On the other hand, information regarding present status of exercise-related research in limited. Therefore, this study seeks to close gap scientific literature by using bibliometric techniques analyze trends, focal points, cutting-edge areas on exercise cirrhosis. September 22, 2023, articles reviews intervention were obtained downloaded from Web Science Core Collection (WoSCC). Subsequently, we employed CiteSpace (version 6.1.R6) conduct knowledge graph analyses. 588 papers 301 scholarly journals written 673 authors 460 institutions spread over 63 countries regions. The most productive nation among them United States. Not only Zobair M. Younossi 1 prolific writers, but he also receives co-citations. Most published University Michigan US, Alberta Canada coming second. Meanwhile, WORLD JOURNAL OF GASTROENTEROLOGY has articles, whereas HEPATOLOGY greatest number Apart theme words, frequently utilized keywords “quality life,” “insulin resistance,” “mortality.” Future may concentrate “obesity,” “sarcopenia,” “Mediterranean diet,” according analysis keyword emergence. used work visually represent topic cirrhosis, offering valuable researchers field’s current possible future direction.
Язык: Английский
Процитировано
1
Biomedicines, Год журнала: 2024, Номер 12(7), С. 1553 - 1553
Опубликована: Июль 12, 2024
Metabolic dysfunctions are among the best documented hallmarks of ageing. Cardiovascular disease, Alzheimer’s cancer, type 2 diabetes mellitus, metabolic-dysfunction-associated steatosis liver and fragility fractures diseases hyperinsulinaemia that reduce life healthspan. We studied effect suppressing ketosis in 10 lean (BMI 20.5 kg/m2 ± 1.4), metabolically healthy, pre-menopausal women (age 32.3 8.9 years) maintaining nutritional (NK) for an average 3.9 years (± 2.3) who underwent three 21-day phases: (NK; P1), suppressed (SuK; P2), returned to NK (P3). Ketosis suppression significantly increased insulin, 1.83-fold (p = 0.0006); glucose, 1.17-fold 0.0088); homeostasis model assessment insulin resistance (HOMA-IR), 2.13-fold 0.0008); leptin, 3.35-fold 0.0010); total osteocalcin, 1.63-fold 0.0138); uncarboxylated 1.98-fold 0.0417) decreased beta-hydroxybutyrate, 13.50-fold 0.0012) glucagon-like peptide-1 (GLP-1), 2.40-fold 0.0209). Sustained showed no adverse health effects may mitigate hyperinsulinemia. All biomarkers basal P1 levels after removing intervention SuK, indicating metabolic flexibility was maintained with long-term euketonaemia.
Язык: Английский
Процитировано
1
Skin Research and Technology, Год журнала: 2024, Номер 30(9)
Опубликована: Сен. 1, 2024
Abstract Background Seborrheic dermatitis (SD) is a common chronic inflammatory skin disease. In recent years, significant progress has been made in the field of SD, but there no bibliometric research yet. This study aims to use methods analyze current status and hot topics understand further trends future development prospects this field. Methods Retrieve core literature on SD from Web Science database conduct detailed analysis using CiteSpace VOSviewer software based factors such as publication volume, countries (regions), institutions, journals, authors, highly‐cited papers, keywords. Results From 1996 2024, total 1436 publications were included analysis. The number shown an increasing trend year by year. USA leading country research. University California System primary institution. International Journal Dermatology journal with highest publications. author Yang Won Lee publications, while article “Seborrheic Dermatitis” (2004) Gupta, A.K. cited most. dermatitis” most frequently occurring keyword. main hotspots frontiers are follows: (1) relationship between other diseases popular topic; (2) Malassezia inflammation SD; (3) Focusing antifungal anti‐inflammatory treatments for frontier direction Conclusion summary research, which helps clinical doctors researchers quickly insights valuable information provides reference decision‐making finding directions.
Язык: Английский
Процитировано
1
Frontiers in Cellular Neuroscience, Год журнала: 2024, Номер 18
Опубликована: Окт. 29, 2024
Following ischemic stroke, non-neuronal cells within the nervous system play a crucial role in maintaining neurovascular unit functions, regulating metabolic and inflammatory processes of system. Investigating functions regulation these cells, particularly immune deepens our understanding complex mechanisms neuroinflammation modulation after stroke provides new perspectives methods for immune-related therapy.
Язык: Английский
Процитировано
1
Scientific Reports, Год журнала: 2024, Номер 14(1)
Опубликована: Дек. 12, 2024
Insulin resistance (IR) is linked to both the vulnerable plaque and stroke risk. However, precise extent of this correlation its impact on risk in carotid artery stenosis patients remain unclear. Therefore, study aims investigate relationship between IR mediating role with stenosis. This included 505 was assessed using triglyceride-glucose (TyG) index. The association TyG index investigated restricted cubic splines (RCS)and adjusted Logistic regression. Additionally, mediation analysis used explore A total 184 (36.4%) events were recorded. RCS curves revealed a positive linear among (P-value < 0.001 P for nonlinear = 0.860). After fully adjusting covariates, emerged as significant predictors events. Mediation indicated that mediated 18.3%, 15.8%, 13.9%, 11.6% different models, respectively. are associated higher In addition, plaques partially
Язык: Английский
Процитировано
1
Cureus, Год журнала: 2023, Номер unknown
Опубликована: Окт. 31, 2023
Stroke remains one of the world's greatest causes disability and death. Insulin resistance (IR) impairs insulin's beneficial effects on brain can change course illness in post-stroke patients. This review aims to find sufficient evidence support causal association IR ischemic stroke with prognosis (PSP). The will also list probable mechanisms better understand how affects pathology. Various articles from PubMed Central, MEDLINE, databases were reviewed, then after careful consideration, 17 selected. studies, using various genetic metabolic markers, have linked increased incidence stroke. Among types strokes investigated this standpoint, silent lacunar infarct stands out as a widely researched subtype. Even though exact pathogenesis is still unclear, current shows an interplay atherosclerosis, embolism, platelet dysfunction. development early neurological decline (END) patients has been used link poor PSP. It acknowledged contributed some way three-month outcomes. Modifying inflammatory pathways developing glucotoxicity are by which After reviewing significant was found role causing well Additional investigation required assess its influence significance subcategories.
Язык: Английский
Процитировано
2
Traditional Chinese Medicine, Год журнала: 2024, Номер 13(07), С. 1697 - 1713
Опубликована: Янв. 1, 2024
Язык: Английский
Процитировано
0
Technology and Health Care, Год журнала: 2024, Номер 32(6), С. 4999 - 5007
Опубликована: Ноя. 8, 2024
BACKGROUND: Cerebral infarction is a health problem of global concern and brings particular burden to medical treatment. OBJECTIVE: To analyze the correlation between insulin resistance (IR) levels changes in cerebral atherosclerosis (AS) degree non-diabetic patients with infarction. METHODS: A total 134 who visited Department Neurology our hospital from May 2019 October 2020 were selected underwent MRA/CTA (Magnetic resonance angiography/Computed tomography angiography) arteries refine cerebrovascular imaging data, according results AS load, divided into mild group severe group, index was calculated HOMA-IR (homeostasis model assessment resistance) evaluate IR level compared two groups. Spearman used load. RESULTS: 54 individuals had 80 AS, an arteries. There significant difference (P< 0.05) difficult gentle link severity found using analysis (r= 0.850, P< 0.05). CONCLUSION: The phenomenon prevalent infarction, closely related AS.
Язык: Английский
Процитировано
0
Нейрохимия, Год журнала: 2024, Номер 41(3), С. 215 - 230
Опубликована: Ноя. 28, 2024
Язык: Английский
Процитировано
0