Trends in Pediatric Hospital Admissions Caused or Contributed by SARS-CoV-2 Infection in England

The Journal of Pediatrics, Год журнала: 2024, Номер 276, С. 114370 - 114370

Опубликована: Окт. 18, 2024

To investigate the changing characteristics of SARS-CoV-2-related pediatric hospital admissions over time. This was a national, observational cohort study from July 1, 2020, to August 31, 2023, using English population-linked electronic health records. We identified 45 203 children younger than 18 years old in whom SARS-CoV-2 either caused or contributed hospitalization, excluding those admitted with "incidental" infection. Studied outcomes were types hospitalization and severe hospitalizations involving critical care inflammatory multisystem syndrome-temporally associated (PIMS-TS). There 920 children: 34 870 (75.9%) attributable COVID-19; 1845 (4.0%) PIMS-TS; 8330 (18.1%) as contributor admission; 875 (1.9%) acquired nosocomial The most notable changes between first 3 waves (March 2020 through November 2021) Omicron era (December 2021 onwards) decrease PIMS-TS 1575 14 020 (11.2%) 270 31 905 (0.8%); reduction use 1175 (8.4%) 1390 (4.4%); decreased mortality rate among hospitalized 521 per 100 000 249 000; median age 4.7 (IQR 0.6,12.3) 1.1 0.3,6.4) years. Of hospitalized, infants, 10.2% had recorded underlying condition, comprised 4225 (30.1%) 15 555 900 (48.8%) since 2022. (P < .001 for all comparisons). Infants are now group affected by SARS-CoV-2, at least partially because they have immunity virus, vulnerable respiratory illnesses.

Язык: Английский

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COVID-19 in Canada: The Canadian COVID-19 experiences project and beyond

Vaccine, Год журнала: 2025, Номер 49, С. 126821 - 126821

Опубликована: Янв. 31, 2025

Язык: Английский

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Mind the gap: examining policy and social media discourse on Long COVID in children and young people in the UK

BMC Public Health, Год журнала: 2025, Номер 25(1)

Опубликована: Апрель 12, 2025

Long COVID in children and young people (CYP) has posed significant challenges for health systems worldwide. Despite its impact on well-being development, policies addressing the needs of CYP remain underdeveloped. This study examines UK using ethical frameworks, integrating policy social media analyses to explore public professional concerns. A mixed-methods approach was applied. Policy documents were reviewed Thompson et al.'s pandemic preparedness framework Campbell Carnevale's child-inclusive model. Social discourse (12,650 posts) analysed Brandwatch™ identify key themes around policies. Data collected triangulated through LISTEN method, which integrates analysis with ensure a holistic understanding systemic gaps perceptions. Analysis highlighted accountability, inclusiveness, transparency development. data reflected dissatisfaction, primarily critiquing government accountability (90% delayed responsiveness (29% posts). Key included limited representation unequal access services. Recommendations include improving transparency, incorporating perspectives policymaking, ensuring equitable care. These findings provide foundation ethically sound inclusive CYP.

Язык: Английский

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Embracing dynamic public health policy impacts in infectious diseases responses: leveraging implementation science to improve practice

Frontiers in Public Health, Год журнала: 2023, Номер 11

Опубликована: Авг. 17, 2023

Rationale The host-pathogen relationship is inherently dynamic and constantly evolving. Applying an implementation science lens to policy evaluation suggests that impacts are variable depending upon key outcomes (feasibility, acceptability, appropriateness costs) conditions contexts. COVID-19 case study Experiences with non-pharmaceutical interventions (NPIs) including masking, testing, social distancing/business school closures during the pandemic response highlight importance of considering public health through evolving contexts, conditions, evidence, perceptions. As acceptability) changed, effectiveness these changed thereby altering impact. Sustainment behavioral change may be a factor determining duration ultimate impact recommendations, particularly for require ongoing compliance at level individual. Practical framework assessing evaluating Updating recommendations as more data alternative become available evidence-based approach grounded in principles sustainability. Achieving ideal real-time updates requires improvements collection analysis infrastructure shift messaging incorporate uncertainty necessity changes. In this review, Dynamic Infectious Diseases Public Health Response Framework presented model practical tool iteratively incorporating into design aim sustaining benefits identifying when policies no longer functioning intended need adapted or de-implemented. Conclusions implications Real-time decision making sensitivity on ground adaptation all levels. When asking about interventions, focus should when, how , long they can achieve future, rather than focusing models intervention assume static impacts, considered re-evaluation meet needs end-user intervention: public.

Язык: Английский

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Effects of COVID-19-targeted non-pharmaceutical interventions on pediatric hospital admissions in North Italian hospitals, 2017 to 2022: a quasi-experimental study interrupted time-series analysis

Frontiers in Public Health, Год журнала: 2024, Номер 12

Опубликована: Апрель 18, 2024

The use of Non-Pharmaceutical Interventions (NPIs), such as lockdowns, social distancing and school closures, against the COVID-19 epidemic is debated, particularly for possible negative effects on vulnerable populations, including children adolescents. This study therefore aimed to quantify impact NPIs trend pediatric hospitalizations during 2 years pandemic compared previous 3 years, also considering two phases according type adopted NPIs.

Язык: Английский

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Impact of COVID‐19 on the Prevalence and Drug Resistance of Bacteria Isolated From Bacterial Meningitis Cerebrospinal Fluid in Shandong Province: A Multicenter Retrospective Study

Journal of Medical Virology, Год журнала: 2024, Номер 96(11)

Опубликована: Ноя. 1, 2024

ABSTRACT Our objective was to evaluate the ramifications of 2019 coronavirus disease (COVID‐19) pandemic on microbial profile and antimicrobial resistance patterns bacteria isolated from cerebrospinal fluid (CSF) specimens patients with bacterial meningitis. We conducted a retrospective analysis laboratory results clinical records about positive CSF cultures reported by SPARSS network 2017 2023. The study covered three distinct periods: January December (before COVID‐19 pandemic), 2020 2022 (during 2023 (after total 5793 isolates collected. Notably, proportion male (61.3%) higher than that females. After COVID‐19, we observed notable shift in seasonal peak pathogens, delay approximately 3 months. Remarkable alterations were evident both pediatric adult isolate profiles. In children, predominant pathogens included coagulase‐negative Staphylococcus (CoNS), Streptococcus pneumonia, Escherichia coli . Notably. there significant decrease CoNS ( p = 0.0039) increase E. 0.0067). adults, top CoNS, Acinetobacter baumannii, Klebsiella pneumoniae pandemic, reduction prevalence A. baumannii 0.0059), while proportions K. , Pseudomonas aeruginosa Enterobacter cloacae, Enterococcus faecalis increased significantly < 0.05). Additionally, among multidrug‐resistant bacteria, detection rate carbapenem‐resistant escalated 0.0375). Antimicrobial susceptibility indicated declining trend rates for certain antibiotics following pandemic. Conversely, imipenem increased. conclusion, has influenced composition, patterns, epidemiological dynamics CSF‐isolated Shandong province. To effectively address these changes, ongoing dynamic surveillance pathogen trends is essential.

Язык: Английский

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Zero-covid advocacy during the COVID-19 pandemic: a case study of views on Twitter/X

Bioethics News, Год журнала: 2024, Номер unknown

Опубликована: Сен. 3, 2024

Язык: Английский

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Characteristic analysis of China's actions against the COVID‐19 in schools and comparison with other countries

Public Health Nursing, Год журнала: 2023, Номер 41(2), С. 255 - 263

Опубликована: Дек. 18, 2023

Abstract Background The outbreak of the COVID‐19 poses a great threat to students globally. China has taken steps keep from becoming infected for more than 30 months, while other countries have also steps. Comparing intentions, implementation, immediate and long‐term effects these initiatives can shed light on care adolescents in schools. Objective focus study is describe full range school prevention measures China, identifying when they work do not. At same time, some typical countries’ schools are presented compared provide comprehensive discussion. Methods This attempted combine data comparison, information analysis, policy interpretation, participatory observation form analytical network. Results China's gone through lucky periods, safety difficult crisis periods. These efforts due government's intense control measures, strict accountability administrators, frequent nucleic acid testing, widespread vaccination, widely implemented online learning. In by implement, price paid government, needs be further assessed reflected upon. Conclusions virus able destroy school's defence with ease. There should consensus among permanent strategy, but severity various appropriately determined, negative effects.

Язык: Английский

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European Surveillance and History of the COVID-19 Pandemic: Updated Epidemiological Assessment (Preprint)

JMIR Public Health and Surveillance, Год журнала: 2024, Номер 10, С. e53551 - e53551

Опубликована: Март 20, 2024

In this study, we built upon our initial research published in 2020 by incorporating an additional 2 years of data for Europe. We assessed whether COVID-19 had shifted from the pandemic to endemic phase region when World Health Organization (WHO) declared end public health emergency international concern on May 5, 2023.

Язык: Английский

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Long-term surveillance of SARS-CoV-2 in the school community from Campo Grande, Brazil

BMC Public Health, Год журнала: 2024, Номер 24(1)

Опубликована: Июль 31, 2024

Abstract Background The COVID-19 pandemic has significantly impacted education systems worldwide, with Brazil being one of the countries longest school closures. Over a million children and teenagers have been affected, leading to increased hunger nutritional deficiencies. This study aimed implement long-term surveillance SARS-CoV-2 infections in public private schools Campo Grande, Brazil, after returning in-person classes. Methods involved testing genomic at 23 Mato Grosso do Sul, from October 18, 2021 November 21, 2022. participants eligible for enrollment were students aged 6–17 years staff members institutions. At time collection, asked if they had symptoms last two weeks. Whole-genome sequencing was conducted identify circulating variants compare them those detected municipality. demographic data clinical history described, logistic regression model used understand how RT-qPCR results could be related different characteristics. Results included 999 participants, most whom women. A total 85 tests positive, an overall positivity rate 3.2%. dynamics case frequency consistent observed municipality during period. common reported cough, rhinorrhea, headache, sore throat. Symptoms associated infection. Eleven lineages identified community samples, occurrence per period similar that found sequences available prevalent within sampling BA.2 (59.3%) BA.5 (29.6%). Conclusions Our findings demonstrate can play crucial role epidemiological surveillance, helping trigger rapid responses pathogens such as SARS-CoV-2. Long-term track outbreaks assess adults transmission. It also contribute preparedness, enabling response emergencies, COVID-19.

Язык: Английский

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