European Surveillance and History of the COVID-19 Pandemic: Updated Epidemiological Assessment (Preprint) DOI
Alexander Lundberg, Scott A Wu, Alan Soetikno

et al.

Published: Oct. 10, 2023

BACKGROUND In this study, we built upon our initial research published in 2020 by incorporating an additional 2 years of data for Europe. We assessed whether COVID-19 had shifted from the pandemic to endemic phase region when World Health Organization (WHO) declared end public health emergency international concern on May 5, 2023. OBJECTIVE first aimed measure there was expansion or contraction Europe at time WHO declaration. Second, used dynamic and genomic surveillance methods describe history situate window declaration within broader history. Third, provided historical context course terms policy disease burden country levels. METHODS addition updates traditional panel estimates original study sequenced SARS-CoV-2 variants Global Initiative Sharing All Influenza Data identify appearance duration concern. Nextclade nomenclature collect clade designations sequences Pangolin lineage SARS-CoV-2. Finally, conducted a 1-tailed <i>t</i> test regional weekly speed greater than outbreak threshold 10. ran iteratively with 6 months across sample period. RESULTS Speed remained below 4 Acceleration jerk were also low stable. While 1-day 7-day persistence coefficients statistically significant, moderate magnitude (0.404 0.547, respectively; <i>P</i>&lt;.001 both). The shift parameters weeks around small insignificant, suggesting little change clustering effect cases future time. From December 2021 onward, Omicron predominant variant viral samples. rolling equal 10 became insignificant April CONCLUSIONS continues circulate Europe, rate transmission ahead previously been nearly continuous state outbreak. more recent trend suggested that no longer reached definition. However, several countries outbreak, conclusion is unclear.

Language: Английский

Trends in Pediatric Hospital Admissions Caused or Contributed by SARS-CoV-2 Infection in England DOI Creative Commons
Harrison Wilde, Christopher Tomlinson, Bilal A. Mateen

et al.

The Journal of Pediatrics, Journal Year: 2024, Volume and Issue: 276, P. 114370 - 114370

Published: Oct. 18, 2024

To investigate the changing characteristics of SARS-CoV-2-related pediatric hospital admissions over time. This was a national, observational cohort study from July 1, 2020, to August 31, 2023, using English population-linked electronic health records. We identified 45 203 children younger than 18 years old in whom SARS-CoV-2 either caused or contributed hospitalization, excluding those admitted with "incidental" infection. Studied outcomes were types hospitalization and severe hospitalizations involving critical care inflammatory multisystem syndrome-temporally associated (PIMS-TS). There 920 children: 34 870 (75.9%) attributable COVID-19; 1845 (4.0%) PIMS-TS; 8330 (18.1%) as contributor admission; 875 (1.9%) acquired nosocomial The most notable changes between first 3 waves (March 2020 through November 2021) Omicron era (December 2021 onwards) decrease PIMS-TS 1575 14 020 (11.2%) 270 31 905 (0.8%); reduction use 1175 (8.4%) 1390 (4.4%); decreased mortality rate among hospitalized 521 per 100 000 249 000; median age 4.7 (IQR 0.6,12.3) 1.1 0.3,6.4) years. Of hospitalized, infants, 10.2% had recorded underlying condition, comprised 4225 (30.1%) 15 555 900 (48.8%) since 2022. (P < .001 for all comparisons). Infants are now group affected by SARS-CoV-2, at least partially because they have immunity virus, vulnerable respiratory illnesses.

Language: Английский

Citations

6

COVID-19 in Canada: The Canadian COVID-19 experiences project and beyond DOI
Helena C. Maltezou

Vaccine, Journal Year: 2025, Volume and Issue: 49, P. 126821 - 126821

Published: Jan. 31, 2025

Language: Английский

Citations

0

Mind the gap: examining policy and social media discourse on Long COVID in children and young people in the UK DOI Creative Commons
Macarena Chepo, Sam Martin, Noémie Deom

et al.

BMC Public Health, Journal Year: 2025, Volume and Issue: 25(1)

Published: April 12, 2025

Long COVID in children and young people (CYP) has posed significant challenges for health systems worldwide. Despite its impact on well-being development, policies addressing the needs of CYP remain underdeveloped. This study examines UK using ethical frameworks, integrating policy social media analyses to explore public professional concerns. A mixed-methods approach was applied. Policy documents were reviewed Thompson et al.'s pandemic preparedness framework Campbell Carnevale's child-inclusive model. Social discourse (12,650 posts) analysed Brandwatch™ identify key themes around policies. Data collected triangulated through LISTEN method, which integrates analysis with ensure a holistic understanding systemic gaps perceptions. Analysis highlighted accountability, inclusiveness, transparency development. data reflected dissatisfaction, primarily critiquing government accountability (90% delayed responsiveness (29% posts). Key included limited representation unequal access services. Recommendations include improving transparency, incorporating perspectives policymaking, ensuring equitable care. These findings provide foundation ethically sound inclusive CYP.

Language: Английский

Citations

0

Effects of COVID-19-targeted non-pharmaceutical interventions on pediatric hospital admissions in North Italian hospitals, 2017 to 2022: a quasi-experimental study interrupted time-series analysis DOI Creative Commons
Giuseppe Maglietta, Matteo Puntoni, Caterina Caminiti

et al.

Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 12

Published: April 18, 2024

The use of Non-Pharmaceutical Interventions (NPIs), such as lockdowns, social distancing and school closures, against the COVID-19 epidemic is debated, particularly for possible negative effects on vulnerable populations, including children adolescents. This study therefore aimed to quantify impact NPIs trend pediatric hospitalizations during 2 years pandemic compared previous 3 years, also considering two phases according type adopted NPIs.

Language: Английский

Citations

2

Impact of COVID‐19 on the Prevalence and Drug Resistance of Bacteria Isolated From Bacterial Meningitis Cerebrospinal Fluid in Shandong Province: A Multicenter Retrospective Study DOI
Chunyan Zhang, Mengyuan Wang, Shuhong Sun

et al.

Journal of Medical Virology, Journal Year: 2024, Volume and Issue: 96(11)

Published: Nov. 1, 2024

ABSTRACT Our objective was to evaluate the ramifications of 2019 coronavirus disease (COVID‐19) pandemic on microbial profile and antimicrobial resistance patterns bacteria isolated from cerebrospinal fluid (CSF) specimens patients with bacterial meningitis. We conducted a retrospective analysis laboratory results clinical records about positive CSF cultures reported by SPARSS network 2017 2023. The study covered three distinct periods: January December (before COVID‐19 pandemic), 2020 2022 (during 2023 (after total 5793 isolates collected. Notably, proportion male (61.3%) higher than that females. After COVID‐19, we observed notable shift in seasonal peak pathogens, delay approximately 3 months. Remarkable alterations were evident both pediatric adult isolate profiles. In children, predominant pathogens included coagulase‐negative Staphylococcus (CoNS), Streptococcus pneumonia, Escherichia coli . Notably. there significant decrease CoNS ( p = 0.0039) increase E. 0.0067). adults, top CoNS, Acinetobacter baumannii, Klebsiella pneumoniae pandemic, reduction prevalence A. baumannii 0.0059), while proportions K. , Pseudomonas aeruginosa Enterobacter cloacae, Enterococcus faecalis increased significantly < 0.05). Additionally, among multidrug‐resistant bacteria, detection rate carbapenem‐resistant escalated 0.0375). Antimicrobial susceptibility indicated declining trend rates for certain antibiotics following pandemic. Conversely, imipenem increased. conclusion, has influenced composition, patterns, epidemiological dynamics CSF‐isolated Shandong province. To effectively address these changes, ongoing dynamic surveillance pathogen trends is essential.

Language: Английский

Citations

2

Embracing dynamic public health policy impacts in infectious diseases responses: leveraging implementation science to improve practice DOI Creative Commons
Westyn Branch‐Elliman, A. Rani Elwy,

David A. Chambers

et al.

Frontiers in Public Health, Journal Year: 2023, Volume and Issue: 11

Published: Aug. 17, 2023

Rationale The host-pathogen relationship is inherently dynamic and constantly evolving. Applying an implementation science lens to policy evaluation suggests that impacts are variable depending upon key outcomes (feasibility, acceptability, appropriateness costs) conditions contexts. COVID-19 case study Experiences with non-pharmaceutical interventions (NPIs) including masking, testing, social distancing/business school closures during the pandemic response highlight importance of considering public health through evolving contexts, conditions, evidence, perceptions. As acceptability) changed, effectiveness these changed thereby altering impact. Sustainment behavioral change may be a factor determining duration ultimate impact recommendations, particularly for require ongoing compliance at level individual. Practical framework assessing evaluating Updating recommendations as more data alternative become available evidence-based approach grounded in principles sustainability. Achieving ideal real-time updates requires improvements collection analysis infrastructure shift messaging incorporate uncertainty necessity changes. In this review, Dynamic Infectious Diseases Public Health Response Framework presented model practical tool iteratively incorporating into design aim sustaining benefits identifying when policies no longer functioning intended need adapted or de-implemented. Conclusions implications Real-time decision making sensitivity on ground adaptation all levels. When asking about interventions, focus should when, how , long they can achieve future, rather than focusing models intervention assume static impacts, considered re-evaluation meet needs end-user intervention: public.

Language: Английский

Citations

6

European Surveillance and History of the COVID-19 Pandemic: Updated Epidemiological Assessment (Preprint) DOI Creative Commons
Alexander Lundberg, Scott A Wu, Alan Soetikno

et al.

JMIR Public Health and Surveillance, Journal Year: 2024, Volume and Issue: 10, P. e53551 - e53551

Published: March 20, 2024

In this study, we built upon our initial research published in 2020 by incorporating an additional 2 years of data for Europe. We assessed whether COVID-19 had shifted from the pandemic to endemic phase region when World Health Organization (WHO) declared end public health emergency international concern on May 5, 2023.

Language: Английский

Citations

0

Long-term surveillance of SARS-CoV-2 in the school community from Campo Grande, Brazil DOI Creative Commons
Daniel Máximo Corrêa Alcântara,

Camila Maria dos Santos,

Jaire Marinho Torres

et al.

BMC Public Health, Journal Year: 2024, Volume and Issue: 24(1)

Published: July 31, 2024

Abstract Background The COVID-19 pandemic has significantly impacted education systems worldwide, with Brazil being one of the countries longest school closures. Over a million children and teenagers have been affected, leading to increased hunger nutritional deficiencies. This study aimed implement long-term surveillance SARS-CoV-2 infections in public private schools Campo Grande, Brazil, after returning in-person classes. Methods involved testing genomic at 23 Mato Grosso do Sul, from October 18, 2021 November 21, 2022. participants eligible for enrollment were students aged 6–17 years staff members institutions. At time collection, asked if they had symptoms last two weeks. Whole-genome sequencing was conducted identify circulating variants compare them those detected municipality. demographic data clinical history described, logistic regression model used understand how RT-qPCR results could be related different characteristics. Results included 999 participants, most whom women. A total 85 tests positive, an overall positivity rate 3.2%. dynamics case frequency consistent observed municipality during period. common reported cough, rhinorrhea, headache, sore throat. Symptoms associated infection. Eleven lineages identified community samples, occurrence per period similar that found sequences available prevalent within sampling BA.2 (59.3%) BA.5 (29.6%). Conclusions Our findings demonstrate can play crucial role epidemiological surveillance, helping trigger rapid responses pathogens such as SARS-CoV-2. Long-term track outbreaks assess adults transmission. It also contribute preparedness, enabling response emergencies, COVID-19.

Language: Английский

Citations

0

Zero-covid advocacy during the COVID-19 pandemic: a case study of views on Twitter/X DOI
Kasper P. Kepp, Kevin Bardosh, Tijl De Bie

et al.

Bioethics News, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 3, 2024

Language: Английский

Citations

0

The COVID-19 Pandemic as a Historical Event: An Analysis of U.S. History Textbooks DOI
Wayne Journell

Journal of Education, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 1, 2024

This study focuses on how four U.S. History textbooks portrayed the COVID-19 pandemic as a recent historical event. The findings from suggest that provided disjointed narrative did not fully explain aspects of pandemic, such why caused so much societal upheaval. also often dodged significant questions about origin virus and lessons learned response. As such, article concludes by arguing these “first drafts history” will do little to help future generations think critically pandemic.

Language: Английский

Citations

0