The Profound Influence of Gut Microbiome and Extracellular Vesicles on Animal Health and Disease

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(7), С. 4024 - 4024

Опубликована: Апрель 4, 2024

The animal gut microbiota, comprising a diverse array of microorganisms, plays pivotal role in shaping host health and physiology. This review explores the intricate dynamics microbiome animals, focusing on its composition, function, impact host–microbe interactions. composition intestinal microbiota animals is influenced by ecology, including factors such as temperature, pH, oxygen levels, nutrient availability, well genetic makeup, diet, habitat, stressors, husbandry practices. Dysbiosis can lead to various gastrointestinal immune-related issues impacting overall productivity. Extracellular vesicles (EVs), particularly exosomes derived from play crucial intercellular communication, influencing transporting bioactive molecules across barriers like brain barriers. Dysregulation gut–brain axis has implications for disorders highlighting potential microbiota-derived EVs disease progression. Therapeutic approaches modulate probiotics, prebiotics, microbial transplants, phage therapy, offer promising strategies enhancing performance. Studies investigating effects therapy have shown results, with improving food safety poultry production systems. Understanding complex interactions between provides valuable insights into mechanisms underlying their Further research this field essential developing effective therapeutic interventions management promote well-being animals.

Язык: Английский

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A review of the role of epigenetic studies for intramuscular fat deposition in beef cattle

Gene, Год журнала: 2024, Номер 908, С. 148295 - 148295

Опубликована: Фев. 21, 2024

Язык: Английский

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Unlocking the potential of soil microbial communities for bioremediation of emerging organic contaminants: omics-based approaches

Microbial Cell Factories, Год журнала: 2024, Номер 23(1)

Опубликована: Июль 25, 2024

The remediation of emerging contaminants presents a pressing environmental challenge, necessitating innovative approaches for effective mitigation. This review article delves into the untapped potential soil microbial communities in bioremediation contaminants. Bioremediation, while promising method, often proves time-consuming and requires deep comprehension intricacies enhancement. Given challenges presented by inability to culture many these microorganisms, conventional methods are inadequate achieving this goal. While omics-based provide an approach understanding fundamental aspects, processes, connections among microorganisms that essential improving strategies. By exploring latest advancements omics technologies, aims shed light on how can unlock hidden capabilities communities, paving way more efficient sustainable solutions.

Язык: Английский

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Designing a More Sustainable and Environmentally Friendly Food Supply: A Roadmap for Future Food and Agricultural Research

ACS Sustainable Resource Management, Год журнала: 2024, Номер 1(8), С. 1639 - 1671

Опубликована: Июль 30, 2024

There is an urgent need to change the way we produce, distribute, and consume foods due several adverse effects modern food supply having on environment, including greenhouse gas emissions, pollution, freshwater use, land biodiversity loss. Concerted efforts are therefore required by scientists around world generate scientific knowledge technological advances needed develop a more sustainable global chain. The purpose of this article highlight some most critical areas where research improve sustainability reduce environmental impact production. These include enhanced agricultural crops livestock animals, improved fertilizers, pesticides, antibiotics, reduced waste, conversion waste streams into energy valuable materials, alternative protein sources, advanced packaging as well many others. A range technologies leading important in science technology, gene editing, nanotechnology, precision fermentation, biotechnology, architecture. An objective stimulate development area so create environmentally friendly system.

Язык: Английский

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A review of genetic resources and trends of omics applications in donkey research: focus on China

Frontiers in Veterinary Science, Год журнала: 2024, Номер 11

Опубликована: Окт. 11, 2024

Omics methodologies, such as genomics, transcriptomics, proteomics, metabolomics, lipidomics and microbiomics, have revolutionized biological research by allowing comprehensive molecular analysis in livestock animals. However, despite being widely used various animal species, on donkeys has been notably scarce. China, renowned for its rich history donkey husbandry, plays a pivotal role their conservation utilization. China boasts 24 distinct breeds, necessitating efforts, especially smaller breeds facing extinction threats. So far, omics approaches employed studies of milk meat, shedding light composition quality. Similarly, methods utilized to explore the basis associated with growth, meat production, quality traits. also unraveled critical microbiota health nutrition, gut microbiome revealing associations factors pregnancy, age, transportation stress, altitude. Furthermore, applications addressed issues, including infectious diseases reproductive problems. In addition, these provided insights into improvement efficiency research. conclusion, methodologies are essential advancing knowledge about donkeys, genetic diversity, across domains. is still infancy, there need continued enhance breeding, welfare beyond.

Язык: Английский

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Various Prebiotics and Probiotics, Their Usage and Importance in Maintaining Normal Microflora in Animal

Indus journal of bioscience research., Год журнала: 2025, Номер 3(1), С. 245 - 254

Опубликована: Янв. 16, 2025

Maintaining balanced microflora in animals is essential for health, immunity, and productivity, particularly considering the increasing global demand antibiotic-free animal products. This review examines contributions of prebiotics probiotics, separately combination as synbiotics, to gastrointestinal health enhancement performance. consolidates contemporary data regarding these therapies' mechanisms, uses, advantages, highlighting their capacity foster microbial stability, improve nutrient absorption, augment immunological responses across diverse species, including poultry, swine, ruminants, aquaculture. Key themes, effectiveness prebiotic probiotic strains, discrepancies literature concerning doses, combinations, species-specific treatments are examined. The additionally analyzes synergistic effects which enhance advantages chemicals. current research landscape, identifies significant knowledge gaps, provides insights into difficulties potential enhancing microbial-based techniques production systems. results underscore promise probiotics sustainable substitutes antibiotics, welfare while mitigating environmental livestock culminates with recommendations future research, necessity longitudinal investigations, established methodology, investigation innovative microbiological possibilities. It enhances comprehension implementation therapies, providing a basis superior management practices agriculture.

Язык: Английский

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The Contributions of Rumen8-Formulated Balanced Rations on the Performance of Lactating Crossbreed Cows in Rukungiri District, South Western Uganda

Journal of Food and Nutrition Sciences, Год журнала: 2025, Номер 13(2), С. 64 - 79

Опубликована: Март 11, 2025

This study investigated the contributions of Rumen8 software-formulated balanced rations on performance lactating crossbreed cows in Rukungiri District, Southwestern Uganda. The aimed to assess level awareness and utilization software among dairy farmers for formulating rations, evaluate perceived benefits challenges implementing Rumen8-formulated identify factors influencing adoption or rejection software. A cross-sectional survey design was employed, an data were collected from 124 respondents using structured questionnaires key informant interviews. Descriptive inferential statistics, including chi-square tests, used analyze data. results showed that moderate, with 58.1% aware However, only 42.7% actively utilized it formulate indicating limited adoption. significant, 77.4% reporting increased milk yield, 67.7% observing improved cow health, 55.6% noting better reproductive performance, 54.8% perceiving more consistent feed quality. Furthermore, 50.0% reported a reduction feeding-related diseases, while 22.6% indicated cost savings feed. Results established as resistance change traditional feeding practices (p=0.000), technical difficulties (p=0.021), difficulty understanding ration recommendations (p=0.044), access necessary technology such computers smartphones (p=0.036). Additionally, lack support (p=0.007) emerged significant barrier, high recommended ingredients (p=0.124) least challenge. most extension services (P=0.000), peer influence (p=0.001), education levels availability trainings (p=0.008), Income (p=0.006), information (p=0.000) leas factor farm size (p=0.648). offers substantial improving overall productivity, its is constrained by both technological behavioral challenges. recommends enhancing farmer services, support, conducting comprehensive training programs boost District. These efforts would contribute sustainable improvement production livelihoods region.

Язык: Английский

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Exploring the hidden complexities of the colostrum and milk microbiome in livestock: emerging insights and challenges

Italian Journal of Animal Science, Год журнала: 2025, Номер 24(1), С. 924 - 946

Опубликована: Апрель 7, 2025

Язык: Английский

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Decoding the dynamics of calves’ respiratory and gut microbiota: exploring stability, resistance, and individual patterns

Research Square (Research Square), Год журнала: 2025, Номер unknown

Опубликована: Апрель 10, 2025

To uncover the intricate relationship between microbiota, host, and environment in early life, we monitored temporal dynamics of nasal gut microbiota 30 veal calves over their first five months. Our findings reveal that stability individuality are specific to each body site. Notably, fecal demonstrated greater diversity, bacterial biomass, stability, homogeneity as animals matured. In contrast, exhibited a skewed structure higher turnover, likely driven by microbial immigration mucociliary clearance. Weather, diet, antibiotics were associated with both microbiotas, alongside host cytokine profiles. Rectal temperature significantly shifted sites, more than diarrhea or respiratory scores. As aged, synchronized across sites emerged. This study presents detailed view patterns connection environment, offering valuable insights for improving management during critical development periods.

Язык: Английский

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A metabolomics perspective on the effect of environmental micro and nanoplastics on living organisms: A review

The Science of The Total Environment, Год журнала: 2024, Номер 932, С. 172915 - 172915

Опубликована: Май 6, 2024

The increasing trend regarding the use of plastics has arisen an exponential concern on fate their derived products to environment. Among these derivatives, microplastics and nanoplastics (MNPs) have been featured for associated environmental impact due low molecular size high surface area, which prompted ubiquitous transference among all interfaces. Due heterogenous chemical composition MNPs, study particles focused a number studies, as result myriad physicochemical properties that contribute co-transference wide range contaminants, thus becoming major challenge scientific community. In this sense, both primary secondary MNPs are well-known be adscribed industrial urbanized areas, from they massively released environment through multiscale level, involving atmosphere, hydrosphere, lithosphere. Consequently, much research conducted understanding interconnection between those interfaces, motivate spread contaminants biological systems, being mostly represented by biosphere, especially phytosphere and, finally, anthroposphere. These findings highlighted potential hazardous risk human health different mechanisms environment, requiring deeper approach define real exposure. As result, there is gap knowledge high-throughput perspective. review, metabolomics-based overview interfaces was proposed, considering technology highly valuable tool decipher opening novel perspective contaminants.

Язык: Английский

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