Anti-Aging Effects of Flavonoids from Plant Extracts
Foods,
Год журнала:
2024,
Номер
13(15), С. 2441 - 2441
Опубликована: Авг. 2, 2024
Aging
is
a
natural
and
irreversible
process,
affecting
living
organisms
by
negatively
impacting
the
tissues'
cells'
morphology
functionality
consequently
being
responsible
for
aging-related
diseases.
Taking
into
account
actual
preoccupations
of
both
consumers
researchers,
healthy
anti-aging
alternatives
are
intensively
studied
in
order
to
address
such
concerns.
Due
their
functional
features,
plant
flavonoids
can
be
considered
valuable
nutraceuticals.
This
paper
highlights
possibilities
use
extracted
from
various
plants
potential
on
skin,
brain,
heart.
Moreover,
anticarcinogenic,
anti-inflammatory,
anti-diabetic
properties
summarized,
along
with
senescence-associated
mechanisms.
Both
nutraceutical
cosmeceutical
fields
continuously
developing
originating
promising
candidates
obtain
products.
Thus,
bioactive
compounds'
extraction
subsequent
involvement
innovative
product
manufacturing
must
carefully
performed
while
aware
intrinsic
extrinsic
factors
that
may
affect
phytochemicals'
structures,
bioavailability,
health
effects.
Язык: Английский
Resveratrol affects proliferation, apoptosis and migration of fibroblast cells as well as inhibits COL1A1/2 and TGFB2/3 gene expression
Journal of Asian Natural Products Research,
Год журнала:
2025,
Номер
unknown, С. 1 - 21
Опубликована: Фев. 18, 2025
Primary
fibroblasts
isolated
from
pterygium
and
skin
pathological
scar
were
identified
by
immunofluorescence
staining.
It
was
found
CCK8
TUNEL
that
high-dose
resveratrol,
a
Chinese
medicine
monomer,
could
inhibit
proliferation,
promote
apoptosis
restrain
migration.
Explored
whole-transcriptome
sequencing
LC-MS/MS,
1531
up-regulated
mRNAs,
1022
down-regulated
79
proteins
84
in
resveratrol-treated
fibroblasts.
shown
KEGG,
GO,
PPI
the
following
bioinformatics
analysis
resveratrol
may
affect
migration
of
fibroblast
through
TGFB2/3
COL1A1/2.
Язык: Английский