The
development
of
multifunctional
films
with
rapidly
killing
microorganisms
and
adsorbing
residual
antibiotics
in
wastewater
remains
a
challenging
endeavor.
In
this
work,
the
chitosan/zinc
ion/polyoxometalate
(CS/Zn
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(7), С. 3836 - 3836
Опубликована: Март 29, 2024
Presently,
millions
worldwide
suffer
from
degenerative
and
inflammatory
bone
joint
issues,
comprising
roughly
half
of
chronic
ailments
in
those
over
50,
leading
to
prolonged
discomfort
physical
limitations.
These
conditions
become
more
prevalent
with
age
lifestyle
factors,
escalating
due
the
growing
elderly
populace.
Addressing
these
challenges
often
entails
surgical
interventions
utilizing
implants
or
grafts,
though
treatments
may
entail
complications
such
as
pain
tissue
death
at
donor
sites
for
along
immune
rejection.
To
surmount
challenges,
engineering
has
emerged
a
promising
avenue
injury
repair
reconstruction.
It
involves
use
different
biomaterials
development
three-dimensional
porous
matrices
scaffolds,
alongside
osteoprogenitor
cells
growth
factors
stimulate
natural
regeneration.
This
review
compiles
methodologies
that
can
be
used
develop
are
important
replacement
Biomaterials
orthopedic
implants,
several
scaffold
types
production
methods,
well
techniques
assess
biomaterials’
suitability
human
use—both
laboratory
settings
within
living
organisms—are
discussed.
Even
researchers
have
had
some
success,
there
is
still
room
improvements
their
processing
techniques,
especially
ones
make
scaffolds
mechanically
stronger
without
weakening
biological
characteristics.
Bone
therefore
area
rise
bone-related
injuries.
Materials Advances,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
The
escalating
environmental
challenges
posed
by
different
waste
sources,
including
agricultural
residues
and
industrial
byproducts,
necessitate
innovative
solutions
for
utilization.
Heliyon,
Год журнала:
2024,
Номер
10(16), С. e36258 - e36258
Опубликована: Авг. 1, 2024
Natural
bone
tissue
has
the
certain
function
of
self-regeneration
and
repair,
but
it
is
difficult
to
repair
large
damage.
Recently,
although
autologous
grafting
"gold
standard"
for
improving
high
cost,
few
donor
sources.
Besides,
allogeneic
causes
greater
immune
reactions,
which
hardly
meet
clinical
needs.
The
engineering
(BTE)
been
developed
promote
repair.
Gelatin,
due
its
biocompatibility,
receives
a
great
deal
attention
in
BTE
research
field.
However,
disadvantages
natural
gelatin
are
poor
mechanical
properties
single
structural
property.
With
development
BTE,
often
used
combination
with
range
natural,
synthetic
polymers,
inorganic
materials
achieve
synergistic
effects
complex
physiological
process
review
delves
into
fundamental
structure
unique
gelatin,
as
well
excellent
necessary
scaffold
materials.
Then
this
explores
application
modified
three-dimensional
(3D)
scaffolds
various
structures
including
3D
fiber
scaffolds,
hydrogels,
nanoparticles.
In
addition,
focuses
on
efficacy
composite
consisting
or
polymeric
materials,
bioactive
ceramics
metallic/non-metallic
defects.
these
gelatin-based
provides
new
ideas
design
good
biosafety.
ACS Biomaterials Science & Engineering,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 11, 2025
Roughly
1.71
billion
people
worldwide
suffer
from
large
bone
abnormalities,
which
are
the
primary
cause
of
disability.
Traditional
grafting
procedures
have
several
drawbacks
that
impair
their
therapeutic
efficacy
and
restrict
use
in
clinical
settings.
A
great
deal
work
has
been
done
to
create
fresh,
more
potent
strategies.
Under
these
circumstances,
a
crucial
technique
for
regeneration
major
lesions
emerged:
tissue
engineering
(BTE).
BTE
involves
biomaterials
can
imitate
natural
design
bone.
To
yet,
no
biological
material
able
fully
meet
parameters
perfect
implantable
material,
even
though
varieties
created
investigated
regeneration.
Against
this
backdrop,
researchers
focused
interest
over
past
few
years
on
subject
nanotechnology
nanostructures
regenerative
medicine.
The
ability
nanoengineered
particles
overcome
current
constraints
strategies─such
as
decreased
cell
proliferation
differentiation,
insufficient
mechanical
strength
materials,
production
extrinsic
factors
required
effective
osteogenesis
revolutionized
field
engineering.
effects
nanoparticles
characteristics
application
materials
main
topics
our
review,
summarizes
most
recent
vitro
vivo
research
context
BTE.