Probiotics
participate
in
various
physiological
activities
and
contribute
to
body
health.
However,
their
viability
bioefficacy
are
adversely
affected
by
gastrointestinal
harsh
conditions,
such
as
gastric
acid,
bile
salts
enzymes.
Fortunately,
encapsulation
based
on
nanomaterials
shows
tremendous
potential
protect
probiotics.
In
this
review,
we
introduced
some
novel
technologies
involving
view
of
predesigned
stability
viability,
selective
adhesion,
smart
release
colonization,
efficacy
exertion
encapsulated
Furthermore,
the
interactions
between
probiotics
tract
were
summarized
analyzed,
with
highlighting
regulatory
mechanisms
intestinal
mechanical
barrier,
chemical
biological
barrier
immune
barrier.
This
review
would
benefit
food
pharmaceutical
industries
preparation
utilization
multifunctional
Frontiers in Microbiology,
Год журнала:
2023,
Номер
14
Опубликована: Авг. 17, 2023
Probiotics,
like
lactic
acid
bacteria,
are
non-pathogenic
microbes
that
exert
health
benefits
to
the
host
when
administered
in
adequate
quantity.
Currently,
research
is
being
conducted
on
molecular
events
and
applications
of
probiotics.
The
suggested
mechanisms
by
which
probiotics
their
action
include;
competitive
exclusion
pathogens
for
adhesion
sites,
improvement
intestinal
mucosal
barrier,
gut
immunomodulation,
neurotransmitter
synthesis.
This
review
emphasizes
recent
advances
emerging
food
industry.
Due
capability
modulate
microbiota
attenuate
immune
system,
could
be
used
as
an
adjuvant
hypertension,
hypercholesterolemia,
cancer,
gastrointestinal
diseases.
Considering
functional
properties,
dairy,
beverage,
baking
industries.
After
developing
latest
techniques
researchers,
can
now
survive
within
harsh
processing
conditions
withstand
GI
stresses
quite
effectively.
Thus,
potential
efficiently
utilized
a
commercial
scale
Journal of Advanced Research,
Год журнала:
2024,
Номер
unknown
Опубликована: Июнь 1, 2024
The
human
gut
hosts
a
diverse
microbial
community,
essential
for
maintaining
overall
health.
However,
antibiotics,
commonly
prescribed
infections,
can
disrupt
this
delicate
balance,
leading
to
antibiotic-associated
diarrhea,
inflammatory
bowel
disease,
obesity,
and
even
neurological
disorders.
Recognizing
this,
probiotics
have
emerged
as
promising
strategy
counteract
these
adverse
effects.
Designed Monomers & Polymers,
Год журнала:
2024,
Номер
28(1), С. 1 - 34
Опубликована: Дек. 31, 2024
This
review
paper
analyzes
recent
advancements
in
bio-polymer
coatings
for
probiotic
microencapsulation,
with
a
particular
emphasis
on
chitosan
and
its
synergistic
combinations
other
materials.
Probiotic
microencapsulation
is
essential
protecting
probiotics
from
environmental
stresses,
enhancing
their
stability,
ensuring
effective
delivery
to
the
gut.
The
begins
an
overview
of
highlighting
significance
safeguarding
through
processing,
storage,
gastrointestinal
transit.
Advances
chitosan-based
encapsulation
are
explored,
including
integration
bio-polymers
such
as
alginate,
gelatin,
pectin,
well
application
nanotechnology
innovative
techniques
like
spray
drying
layer-by-layer
assembly.
Detailed
mechanistic
insights
integrated,
illustrating
how
influences
gut
microbiota
by
promoting
beneficial
bacteria
suppressing
pathogens,
thus
role
prebiotic
or
synbiotic.
Furthermore,
delves
into
chitosan's
immunomodulatory
effects,
particularly
context
inflammatory
bowel
disease
(IBD)
autoimmune
diseases,
describing
immune
signaling
pathways
influenced
linking
changes
improvements
systemic
immunity.
Recent
clinical
trials
human
studies
assessing
efficacy
chitosan-coated
presented,
alongside
discussion
practical
applications
comparison
vitro
vivo
findings
highlight
real-world
relevance.
sustainability
sources
impact
addressed,
along
novel
concept
gut-brain
axis.
Finally,
emphasizes
future
research
needs,
development
personalized
therapies
exploration
techniques.
Critical Reviews in Food Science and Nutrition,
Год журнала:
2022,
Номер
64(8), С. 2130 - 2156
Опубликована: Сен. 19, 2022
Probiotic
products'
economic
value
and
market
popularity
have
grown
over
time
as
more
people
discover
their
health
advantages
adopt
healthier
lifestyles.
There
is
a
significant
societal
cultural
interest
in
these
products
known
foods
or
medicines.
Products
containing
probiotics
that
claim
to
provide
must
maintain
"minimum
therapeutic"
level
(10
Frontiers in Nutrition,
Год журнала:
2022,
Номер
9
Опубликована: Сен. 27, 2022
The
burden
of
public
health
challenges
associated
with
the
western
dietary
and
living
style
is
growing.
Nutraceuticals
have
been
paid
increasing
attentions
due
to
their
effects
in
promotion
health.
However,
gastrointestinal
(GI)
tract,
nutraceuticals
suffer
from
not
only
harsh
acidic
environment
stomach
a
variety
digestive
enzymes,
but
also
antibacterial
activity
intestinal
bile
salts
action
protease
gut
microbiota.
amount
arriving
at
sites
GI
tract
for
absorption
or
exerting
bioactivities
always
unfortunately
limited,
which
puts
forward
high
requirements
protection
certain
contents
during
oral
consumption.
Hydrogels
are
three-dimensional
polymeric
porous
networks
formed
by
cross-linking
polymer
chains,
can
hold
huge
amounts
water.
Compared
other
carries
size
microscopic
scale
such
as
nanoparticle
microcapsules,
hydrogels
could
be
considered
more
suitable
delivery
systems
food
macroscopic
bulk
properties,
adjustable
viscoelasticity
large
spatial
structure
embedding
nutraceuticals.
Regarding
applications
food,
natural
polymer-based
commonly
safe
popular
source
appealing
characteristics
affordability,
biodegradability
biocompatibility.
Although
chemical
crosslinking
has
widely
utilized
preparation
hydrogels,
it
prefers
physical
researches
food.
reasonable
design
essential
seeking
favorable
functionalities
apply
system,
possible
obtain
enhanced
adhesive
property,
acid
stability,
resistant
salt,
controlled
release
behavior.
prepared
proteins,
polysaccharides
mix
them
deliver
functional
ingredients,
mainly
phenolic
components,
vitamins,
probiotics
discussed
inspiration
wide
systems.
Further
efforts
might
made
situ
formation
through
interaction
among
polymers
small-molecular
elevation
loading
development
well
targeting
modification
microbiota
hydrogels.
