Photo-Crosslinked Chitosan-Gelatin Xerogel-Like Coating Onto “Cold” Plasma Functionalized Poly(Lactic Acid) Film as Cell Culture Support DOI
Elena Stoleru, Mihai Brebu, Iuliana Stoica

и другие.

Опубликована: Янв. 1, 2023

This paper reports on biofunctionalisation of a poly(lactic acid) (PLA) film by surface activation through cold plasma treatment followed coating with chitosan-gelatin xerogel. The UV cross-linking the xerogel precursor was simultaneously performed fixation onto PLA support. has strong effect properties, in terms wettability, free energy, morphology and micromechanical features. hydrophilic – hydrophobic character surface, determined contact angle measurements, tuned along process, passing from moderate to enhanced activated that favors adhesion then coating. Lewis amphoteric porous xerogel-like as revealed scanning electron microscopy images. By riboflavin mediated becomes high adhesive more pronounced plasticity, shown AFM force-distance spectroscopy. Thus prepared coated supports were successfully tested for growth dermal fibroblasts, which are known their induction potential chondrogenic cells, is very important cartilage tissue engineering.

Язык: Английский

Calcium Phosphate Biomaterials for 3D Bioprinting in Bone Tissue Engineering DOI Creative Commons

Nelli Tolmacheva,

Amitava Bhattacharyya, Insup Noh

и другие.

Biomimetics, Год журнала: 2024, Номер 9(2), С. 95 - 95

Опубликована: Фев. 6, 2024

Three-dimensional bioprinting is a promising technology for bone tissue engineering. However, most hydrogel bioinks lack the mechanical and post-printing fidelity properties suitable such hard regeneration. To overcome these weak properties, calcium phosphates can be employed in bioink to compensate of certain characteristics. Further, extracellular matrix natural contains this mineral, resulting its structural robustness. Thus, are necessary components This review paper examines different recently explored phosphates, as component potential bioinks, biological, required 3D bioprinted scaffolds, exploring their distinctive that render them favorable biomaterials The discussion encompasses recent applications adaptations 3D-printed scaffolds built with delving into scientific reasons behind prevalence types over others. Additionally, elucidates interactions polymer hydrogels applications. Overall, current status phosphate/hydrogel engineering has been investigated.

Язык: Английский

Процитировано

14

Additive manufacturing in nano drug delivery systems DOI Creative Commons

Md. Habibur Rahman,

Nilufar Yasmin Liza,

Khan Rajib Hossain

и другие.

Pharmaceutical Science Advances, Год журнала: 2024, Номер 2, С. 100036 - 100036

Опубликована: Фев. 21, 2024

The adoption of innovative mixing and fabrication technologies in the pharmaceutical industry has inspired research on nano-drugs expanded scope study field. Researchers' interest recently discovered drug delivery nanoparticles increased significantly. This is especially seen specific preparation as carriers through use three-dimensional (3D) printing, a modern additive manufacturing (AM) technology. benefits 3D at nanoscale, make it an technology that could revolutionize regenerative medicine industries. laborious creation intricate structures made possible by nanoscale printing brings up possibility developing nanomedicine producing functioning tissues organs. uses AM nano systems (NDDS) are highlighted this study, with focus how can improve release kinetics, enhance therapeutic efficacy, minimize side effects. A new era personalized begun development patient-specific formulations customization capabilities printing. review discusses various NDDS while addressing issues including scalability, biocompatibility, regulatory concerns. highlights integration between nanotechnology ongoing activities solutions. As develops further, potential to completely change field providing fresh approaches complex problems contemporary healthcare advancing ideas behind delivery.

Язык: Английский

Процитировано

11

Biofabrication of engineered tissues by 3D bioprinting of tissue specific high cell-density bioinks DOI Creative Commons
Oju Jeon, Hyoeun Park, J. Kent Leach

и другие.

Materials Today, Год журнала: 2025, Номер unknown

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0

Recent advances in 3D bioprinting of polysaccharide-based bioinks for fabrication of bioengineered tissues DOI

Kasula Nagaraja,

Pratik Dhokare,

Amitava Bhattacharyya

и другие.

Molecular Systems Design & Engineering, Год журнала: 2024, Номер 9(10), С. 977 - 999

Опубликована: Янв. 1, 2024

Complex multilayered tissues have been regenerated by extrusion-based 3D bioprinting with biocompatible polymers. Multilayer fabrications tissue-specific bioinks are possible controlling gel properties including interaction between layers.

Язык: Английский

Процитировано

3

Photo-crosslinked chitosan-gelatin xerogel-like coating onto “cold” plasma functionalized poly(lactic acid) film as cell culture support DOI Creative Commons
Mihai Brebu, Daniela Pamfil, Iuliana Stoica

и другие.

Carbohydrate Polymers, Год журнала: 2024, Номер 339, С. 122288 - 122288

Опубликована: Май 17, 2024

This paper reports on biofunctionalisation of a poly(lactic acid) (PLA) film by surface activation through cold plasma treatment followed coating with chitosan-gelatin xerogel. The UV cross-linking the xerogel precursor was simultaneously performed fixation onto PLA support. has strong effect properties, in terms wettability, free energy, morphology and micromechanical features. hydrophilic - hydrophobic character surface, determined contact angle measurements, tuned along process, passing from moderate to enhanced activated which favors adhesion, then coating. Lewis amphoteric porous xerogel-like morphology, as revealed scanning electron microscopy images. By riboflavin mediated becomes high adhesive more pronounced plasticity, shown AFM force-distance spectroscopy. Thus prepared surface-coated supports were successfully tested for growth dermal fibroblasts, are known their induction potential chondrogenic cells, is very important cartilage tissue engineering.

Язык: Английский

Процитировано

2

Characterization of Pentenoate-Functionalized Hyaluronic Acid and Pentenoate-Functionalized Gelatin Hydrogels for Printing and Future Surgical Placement in Regenerative Medicine Applications DOI
Emi A. Kiyotake, Emily E. Thomas,

Susan L. Nimmo

и другие.

Materialia, Год журнала: 2024, Номер 38, С. 102242 - 102242

Опубликована: Сен. 25, 2024

Язык: Английский

Процитировано

1

Engineering smart hydrogels for intelligent drug delivery DOI

Mitra Baghali,

Hakimeh Ziyadi, Antonio Di Martino

и другие.

Polymer Bulletin, Год журнала: 2024, Номер unknown

Опубликована: Дек. 17, 2024

Язык: Английский

Процитировано

1

Ex vivo enhancement of CD8+ T cell activity using functionalized hydrogel encapsulating Tonsil-derived lymphatic endothelial cells DOI Creative Commons

Heesun Hong,

Chan Hum Park,

Ji Seung Lee

и другие.

Theranostics, Год журнала: 2024, Номер 15(3), С. 850 - 874

Опубликована: Дек. 2, 2024

Язык: Английский

Процитировано

0

Photo-Crosslinked Chitosan-Gelatin Xerogel-Like Coating Onto “Cold” Plasma Functionalized Poly(Lactic Acid) Film as Cell Culture Support DOI
Elena Stoleru, Mihai Brebu, Iuliana Stoica

и другие.

Опубликована: Янв. 1, 2023

This paper reports on biofunctionalisation of a poly(lactic acid) (PLA) film by surface activation through cold plasma treatment followed coating with chitosan-gelatin xerogel. The UV cross-linking the xerogel precursor was simultaneously performed fixation onto PLA support. has strong effect properties, in terms wettability, free energy, morphology and micromechanical features. hydrophilic – hydrophobic character surface, determined contact angle measurements, tuned along process, passing from moderate to enhanced activated that favors adhesion then coating. Lewis amphoteric porous xerogel-like as revealed scanning electron microscopy images. By riboflavin mediated becomes high adhesive more pronounced plasticity, shown AFM force-distance spectroscopy. Thus prepared coated supports were successfully tested for growth dermal fibroblasts, which are known their induction potential chondrogenic cells, is very important cartilage tissue engineering.

Язык: Английский

Процитировано

0