Sleep Deprivation-Induced Oxidative Stress in Rat Models: A Scoping Systematic Review

Antioxidants, Год журнала: 2023, Номер 12(8), С. 1600 - 1600

Опубликована: Авг. 11, 2023

Sleep deprivation is highly prevalent in the modern world, possibly reaching epidemic proportions. While multiple theories regarding roles of sleep exist (inactivity, energy conservation, restoration, brain plasticity and antioxidant), unknowns still remain proposed antioxidant sleep. The existing experimental evidence often contradicting, with studies pointing both toward against presence oxidative stress after deprivation. main goals this review were to analyze data relationship between stress, attempt further clarify aspects surrounding identify current knowledge gaps. Systematic searches conducted three major online databases for performed on rat models measurements, published 2015 2022. A total 54 included review. Most results seem point changes parameters deprivation, suggesting an role Alterations these observed paradoxical protocols strains. Furthermore, effects extend beyond central nervous system, affecting other body sites periphery. recovery seems be characterized by increased variability, normalizations some long-lasting Surprisingly, most revealed a response following However, origin impact during somewhat unclear. definitive exclusion influence protocol not possible, available suggest that may determined itself as opposed conditions. Due fact, could attributed directly

Язык: Английский

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Mental health symptoms one year after acute COVID-19 infection: Prevalence and risk factors

Revista de Psiquiatría y Salud Mental, Год журнала: 2022, Номер 16, С. 38 - 46

Опубликована: Июнь 17, 2022

Emerging evidence suggests that mental health symptoms in COVID-19 survivors are higher than expected, possibly indicating such more likely to develop post-infection just persist as a residual component of the acute phase. It is thus imperative investigate potential development post-COVID syndrome longer-term and identify its risk factors.A prospective study investigated associated with determinants over 12-month period following disease onset all consecutive adult inpatients outpatients attending tertiary referral hospital from March May 2020.A total 479 patients (female, 52.6%) were followed-up for 12 months after onset. Of them, 47.2% still presenting at least one symptom. While most subsided compared (all p < 0.001), significant increase was observed only psychiatric disorders (10.2%) lack concentration focus (20%; 0.001). Patients related multiple body systems contracting ≤ 0.034) suffer domain-related follow-up. Also, post infection found those suffering (p = 0.005).Findings this may have important public implications, they underlie increased need support survivors.Nuevas evidencias sugieren que los síntomas de salud en supervivientes son mayores lo esperado, posiblemente indica es más probable dichos se desarrollen después la infección vez sólo persistir como componente fase aguda. Por tanto, imperativo investigar el posible desarrollo un síndrome largo plazo e identificar sus factores riesgo.Un estudio prospectivo investigó asociados y determinantes durante periodo meses tras inicio enfermedad todos pacientes adultos consecutivos con COVID-19, hospitalizados ambulatorios, acudieron tercer nivel entre marzo mayo 2020.Un (mujeres, 52,6%) fueron seguidos del COVID-19. De ellos, 47,2% seguía presentando al menos síntoma. Mientras mayoría disminuyeron comparación (todos 0,001), observó aumento significativo solamente trastornos psiquiátricos (10,2%) falta concentración enfoque 0,001). Los presentaban relacionados múltiples sistemas cuerpo contraer 0,034) tenían probabilidades sufrir dominio seguimiento. Además, encontró mayor riesgo presentar sufrían 0,005).Los resultados este pueden tener importantes implicaciones para pública, ya subyacen necesidad apoyo

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Impact of 6-months of an advanced hybrid closed-loop system on sleep and psychosocial outcomes in youth with type 1 diabetes and their parents

Diabetes Research and Clinical Practice, Год журнала: 2024, Номер 207, С. 111087 - 111087

Опубликована: Янв. 1, 2024

Язык: Английский

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Recent Progress in Long-Term Sleep Monitoring Technology

Biosensors, Год журнала: 2023, Номер 13(3), С. 395 - 395

Опубликована: Март 17, 2023

Sleep is an essential physiological activity, accounting for about one-third of our lives, which significantly impacts memory, mood, health, and children’s growth. Especially after the COVID-19 epidemic, sleep health issues have attracted more attention. In recent years, with development wearable electronic devices, there been studies, products, or solutions related to monitoring. Many mature technologies, such as polysomnography, applied clinical practice. However, it urgent develop non-contacting devices suitable household continuous This paper first introduces basic knowledge significance Then, according types signals monitored, this describes research progress bioelectrical signals, biomechanical biochemical used not ideal monitor quality whole night based on only one signal. Therefore, reviews multi-signal monitoring systematic schemes. Finally, a conclusion discussion are presented propose potential future directions prospects

Язык: Английский

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Long COVID and rheumatology: Clinical, diagnostic, and therapeutic implications

Best Practice & Research Clinical Rheumatology, Год журнала: 2022, Номер 36(4), С. 101794 - 101794

Опубликована: Ноя. 8, 2022

Язык: Английский

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Family Resilience and Adolescent Mental Health during COVID-19: A Moderated Mediation Model

International Journal of Environmental Research and Public Health, Год журнала: 2022, Номер 19(8), С. 4801 - 4801

Опубликована: Апрель 15, 2022

The COVID-19 pandemic has impacted and is still impacting people's lives, including physical mental health. Family plays an important role in adolescent health due to the long staying at home.This paper aimed investigate impact of family resilience on during pandemic, mediation stress perception moderation meta-mood.A total 2691 Chinese adolescents were recruited using convenient sampling. Their health, resilience, meta-mood surveyed. Multivariate statistics used analyze data.Our results showed that (1) about 36.7% our sample have some problems; (2) can positively predict whereas negatively health; (3) mediates relationship between (4) moderates perception, i.e., first half role.Our indicate one either improve or adolescents' relieve problems.

Язык: Английский

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The Impact of the COVID-19 Pandemic on Inpatient Admissions for Psychotic and Affective Disorders: The Experience of a Large Psychiatric Teaching Hospital in Romania

Healthcare, Год журнала: 2022, Номер 10(8), С. 1570 - 1570

Опубликована: Авг. 18, 2022

The COVID-19 pandemic resulted in a global sanitary crisis and, addition, elicited serious mental health consequences. utilization of psychiatric hospital-based services acts as an indicator public health. Therefore, this research sought to investigate differences the numbers and characteristics inpatient admissions for psychotic affective disorders at largest Romanian hospital between period lockdown (16 March−15 May 2020) another three corresponding periods: same year pre-lockdown January−15 March 2020), immediate post-lockdown May−15 July two years later 2022). A retrospective analysis was performed. study included total 6604 patients. Inpatient decreased during comparison with (p < 0.001 p 0.001, respectively) respectively). For both disorders, decrease age patients admitted lockdown, compared 0.05 respectively), observed. length stay higher immediately 0.001). Collectively, present findings provide glimpse long-term consequences measures on patients’ access healthcare form hospitalization, these could basis development different approach times crisis.

Язык: Английский

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The impact of COVID-19 pandemic on sleep duration and mental health among middle school students: a 3-year cross-sectional survey

Frontiers in Public Health, Год журнала: 2025, Номер 13

Опубликована: Янв. 29, 2025

Background Since the outbreak of COVID-19 in late 2019, and until Chinese government downgraded pandemic control measures to Category B management January 2023, various epidemic prevention were implemented across regions based on local spread virus. Correspondingly, educational formats shifted between online offline teaching according situation. Changes daily life methods, along with high initial mortality rate COVID-19, have had varying degrees negative impact mental health (MH) adolescents. Purposes This study aimed explore status sleep duration (SD) MH adolescents, investigate relationship SD middle school students, evaluate protective effect MH. Methods Using a convenient sampling method, 6 junior schools 3 senior Guiyang City, China, selected. Random samples from two classes per grade each chosen for survey. The was conducted annually three consecutive years using Mental Health Inventory Middle-school students (MMHI-60) scale self-designed questionnaire. Data analyzed IBM SPSS version 26.0 software, employing ANOVA, cross-tabulation, generalized linear models examine scores. Results scores 2021, 2022, 2023 436.41 ± 71.21 min/day, 423.69 61.71 445.26 65.04 min/day (F = 41.44, p &lt; 0.001), 1.72 0.63, 1.87 0.73, 1.79 0.67 18.31, 0.001). compliance rates 34.1%, 23.9%, 33.2%, problem detection 27.9%, 36.4%, 33.4%, respectively; there is significant correlation among ( P 0.001); effects 1.859 times, 2.156 1.516 times higher than those non-compliance (all Conclusion Meeting standard factor adolescent its severe long-term both differences observed genders academic levels. greater severity stricter measures, more etc.

Язык: Английский

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Sleep quality and associated factors in Latin American medical students: a cross-sectional and multicenter study

BMC Public Health, Год журнала: 2025, Номер 25(1)

Опубликована: Фев. 24, 2025

Existing literature has not stablished the factors associated with sleep quality, which requires further research in context of mental health future medical professionals. This study aimed to determine prevalence and related quality Latin American students during COVID-19 pandemic. Cross-sectional multicenter analytic secondary data analysis students. The sampling was non-probabilistic snowball sampling. Sleep (Pittsburgh questionnaire) its association psychosocial-academic variables, depressive symptoms (PHQ-9 questionnaire), anxious (GAD-7 resilience (abbreviated CD-RISC eating disorder (EAT-26 physical activity (IPAQ questionnaire-short version), tobacco alcohol consumption (ASSIST burnout syndrome (Maslash were assessed. Prevalence ratios 95% confidence intervals estimated. Of 2019 students, poor 62.2% (95%CI: 60.00%-64.28%). In multiple regression model, that positively poorer female sex (PR: 1.13), moderate risk smoking 1.08), presence severe 2.19 PR: 2.14, respectively), as well anxiety 1.21 1.22, respectively). On other hand, negatively having received training on 0.95), a history 0.80), high level 0.86). It found had quality. Factors such sex, smoking, while training, disease, linked better These findings are key for public health, affects academic performance, underscoring importance intervening these improve student well-being.

Язык: Английский

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The effects of L-theanine consumption on sleep outcomes: a systematic review and meta-analysis.

Sleep Medicine Reviews, Год журнала: 2025, Номер 81, С. 102076 - 102076

Опубликована: Фев. 25, 2025

This systematic review ansd meta-analysis aimed to evaluate the effects of L-theanine, a non-proteinogenic amino acid found in tea, on sleep outcomes. Literature searches were conducted five electronic databases (APA PsycINFO, CINAHL, Medline, Scopus, Web Science), and one register (Cochrane Central Register Controlled Trials) from inception until September 2024. Randomised controlled trials investigating L-theanine supplementation quality humans all ages health status included. Nineteen articles (N = 897 participants) selected 18 included meta-analysis. was shown significantly improve subjective onset latency (SMD 0.15, 95 % CI [0.01, 0.29], p 0.04; n 10 studies), daytime dysfunction 0.33, [0.16, 0.49], < 0.001; 9 overall score 0.43, [0.04, 0.83], 0.03; 12 studies). The findings indicate potential use management disturbances; however, lack studies "pure" warrants further investigation. Future are needed determine adequate dose duration for improving maintaining healthy clinical populations.

Язык: Английский

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