Journal of Consumer Health on the Internet,
Год журнала:
2024,
Номер
28(1), С. 40 - 55
Опубликована: Янв. 2, 2024
This
study
addresses
the
growing
interest
in
Dry
Eye
Disease
(DED)
by
evaluating
quality
of
DED
videos
on
YouTube,
gauging
audience
engagement,
and
identifying
factors
influencing
viewership.
In
this
cross-sectional
study,
we
collected
videos,
during
July
to
September
2023,
using
keyword
'dry
eye'.
A
data
collection
form,
including
general
characteristics
engagement
metrics,
was
employed.
Two
medical
experts
rated
Patient
Education
Materials
Assessment
Tool-Audio
Visual
(PEMAT-A/V)
custom
clinical
scoring
tool.
Among
total
52
assessed,
80.8%
speakers
were
Medical
Doctors.
Regarding
symptoms,
only
21.2%
mentioned
excessive
tearing
34.6%
stated
blurry
vision.
The
majority
(69.2%)
eye
drops
as
a
treatment.
Lifestyle
modification
limiting
screen
use
addressed
videos.
Out
20,
mean
index
score
7.5
(±5.4).
understandability
(total
=
11)
actionability
3)
scores
8.1
(±2.0)
1.7
(±0.98),
respectively.
PEMAT-A/V
individual
items,
13.5%
offered
content
summaries,
23.5%
explained
actions
explicitly.
number
likes,
comments
views
significantly
higher
for
with
scores.
performed
well
items;
however,
explicit
actionable
items
need
be
included
Moreover,
public
more
likes
understandable
To
maximize
benefit
audience,
recommend
healthcare
professionals
guidelines
health
education
content.
Biosurface and Biotribology,
Год журнала:
2025,
Номер
11(1)
Опубликована: Янв. 1, 2025
ABSTRACT
Compromised
hydration
and
biolubrication
leads
to
untreatable
disorders
like
osteoarthritis
(OA),
dry
eye
disease
(DED)
mouth
(xerostomia).
Only
symptomatic
treatment
is
possible
through
bioactive
molecules.
This
study
aims
investigate
the
properties
of
natural
modified
phytoglycogen
nanoparticles
(PGNPs)
which
have
shown
superlubricious
behaviour
at
mica‐mica
sliding
interface.
PGNPs
were
cationised
(CPGNPs)
by
modifying
hydroxyl
groups
into
quaternary
amine
groups.
Dynamic
light
scattering
(DLS)
was
used
characterise
size
zeta‐potential
both
PGNPs.
The
quartz
crystal
microbalance
with
dissipation
(QCM‐D)
their
adhesion
collagen
type
II
mucin.
tribological
studied
using
polydimethylsiloxane
(PDMS)‐glass
system,
cartilage‐glass
(synovial)
eye‐eyelid
(ocular)
systems.
CPGNPs
adhered
better
than
on
synovial
ocular
surfaces.
Both
particle
types
showed
good
lubrication
for
cartilage
but
no
differences
between
in
system
observed.
Overall,
observed
lubricating
indicating
great
potential
towards
a
implementation
osteoarthritis.
Journal of Clinical & Translational Ophthalmology,
Год журнала:
2025,
Номер
3(2), С. 6 - 6
Опубликована: Март 26, 2025
Over
2.2
billion
people
across
the
globe
face
significant
barriers
to
accessing
essential
ophthalmic
care,
with
elderly,
rural,
and
refugee
populations
being
disproportionately
affected,
deepening
existing
disparities
in
eye
care.
Three-dimensional
printing
is
a
novel
technology
that
has
potential
transform
field
improve
access
by
alleviating
many
patient-specific
barriers.
This
article
delves
into
evolution
of
3D
within
ophthalmology,
highlighting
its
current
applications
future
potential.
It
explores
various
techniques
numerous
biomaterials
discussing
their
effectiveness
creating
advanced
solutions
such
as
bioengineered
corneas,
ocular
prosthetics,
innovative
treatments
for
dry
syndrome,
from
punctal
plugs
lacrimal
gland
models.
Additionally,
revolutionized
drug
delivery
systems
conditions
like
glaucoma,
retinal
diseases,
brachytherapy.
Whether
through
printed
contact
lens-based
or
polycaprolactone
implants
biodegrade
provide
sustained
release
without
adverse
effects,
these
hold
immense
field.
Despite
promise,
integration
clinical
practice
presents
challenges,
which
addresses
alongside
strategies
overcoming
them.
By
mapping
out
technological
advancements
this
review
offers
roadmap
enhancing
global
care
accessibility
improving
patient
outcomes
on
scale.
ACS Sustainable Chemistry & Engineering,
Год журнала:
2024,
Номер
12(42), С. 15671 - 15681
Опубликована: Окт. 7, 2024
Scalable
and
sustainable
synthesis
of
key
fragments
with
a
low
environmental
impact
is
crucial
for
API
synthesis.
Herein,
we
report
the
benzofuran-6-carboxylic
acid,
fragment
drug
lifitegrast
used
treating
keratoconjunctivitis
sicca.
Unlike
existing
routes,
this
features
transition
metal-free,
three-step
protocol
using
general
reagents.
The
scalability
process
was
successfully
demonstrated
on
100
g
scale.
target
compound
obtained
in
pure
form
(98.2%
HPLC
purity)
without
chromatographic
purification.
methods
avoid
use
metals
cryogenic
temperatures
employed
known
routes.
A
life
cycle
analysis
comparison
current
routes
indicated
that
present
route
leaves
smaller
carbon
footprint.
By
metal-free
base
catalyst,
significant
benefits,
mainly
CO2
emission
savings,
enhanced
human
health
quality,
lower
mineral
depletion,
affirming
sustainability
lowering
reaction
steps.
Designing
chemical
syntheses
alternative
pathways
reduces
input,
supports
chemists
decision-making,
addresses
to
low-carbon
processes
products.
Ophthalmology and Therapy,
Год журнала:
2023,
Номер
13(1), С. 251 - 266
Опубликована: Ноя. 10, 2023
An
innovative
eye
drops
formulation
containing
0.2%
hyaluronic
acid
and
a
low
concentration
of
hydrocortisone
(0.001%;
hereafter
HALH)
has
been
recently
placed
on
the
market
(Idroflog
Sustainable Development,
Год журнала:
2024,
Номер
unknown
Опубликована: Апрель 29, 2024
Abstract
The
significance
of
information
and
communication
technologies
(ICT)
for
the
Paris
Climate
Agreement
is
continuously
increasing
because
its
growing
energy
consumption.
Here
we
examine
question
smartphone
extend
investigation
to
more
aspects
sustainability.
Critical
issues
are
identified
ten
UN
Sustainable
Development
Goals.
Measurements
consumption
show
that
a
significant
savings
potential
can
be
unlocked
by
reducing
data
outflow
large
amount
personal
stored
in
centers.
Main
discrepancies
also
traced
oligopolistic
market
structure
operating
systems
(OSs),
messenger
services,
social
media
apps.
Technical
means
sustainable
use
suggested
as
alternative
OSs,
channels
Fediverse,
well
free
open‐source
software.
Finally,
societal
conditions
emphasized
make
OSs
apps
diverse
so
generally
prevail.
Diagnostics,
Год журнала:
2024,
Номер
14(13), С. 1349 - 1349
Опубликована: Июнь 25, 2024
In
this
study,
we
aimed
to
evaluate
the
association
between
severity
of
coronary
heart
disease
(CHD)
and
subsequent
blepharitis.
This
retrospective
population-based
cohort
study
was
conducted
using
National
Health
Insurance
Research
Database
(NHIRD)
Taiwan.
The
participants
with
a
CHD
diagnosis
were
divided
into
mild
severe
groups
at
1:2
ratio,
according
whether
percutaneous
intervention
(PCI)
performed.
main
outcomes
development
blepharitis
application
antibiotics.
Cox
proportional
hazard
regression
performed
obtain
adjusted
ratio
(aHR)
for
blepharitis,
95%
confidence
interval
(CI)
groups.
There
22,161
15,369
events
plus
9597
4500
episodes
in
groups,
respectively.
group
showed
significantly
higher
incidence
(aHR,
1.275;
CI:
1.051–1.912,
p
=
0.0285),
whereas
not
different
0.981;
0.945–1.020,
0.3453).
cumulative
probability
than
(p
<
0.001).
subgroup
analyses,
correlation
more
significant
patients
older
70
years
compared
younger
0.0115).
conclusion,
is
associated
CHD,
prominent
individuals
years.