Assessment of Awareness of Dry Eye in Youth and its Association with Extended Screen Time Use in Saudi Arabia DOI Open Access

Shaima Sulaiman Alharbi,

Ghadah Mohammed Almutairi,

Abeer Alkhodier

et al.

Open Access Macedonian Journal of Medical Sciences, Journal Year: 2024, Volume and Issue: 12(4), P. 542 - 548

Published: Dec. 15, 2024

BACKGROUND: Dry eye disease (DED) is a multifactorial condition characterized by discomfort and visual disturbances, often linked to prolonged screen time other environmental or lifestyle factors. In Saudi Arabia, DED prevalence increasing, especially among younger populations. AIM: This study aimed assess the of DED, its associated risk factors, awareness youth. METHODOLOGY: A cross-sectional questionnaire-based was conducted targeting 366 The sample recruited randomly, with majority (89.3%) from central region. Participants ranged in age 19 over 55 years, mean 28.6 ± 11.7 years. Data were collected via self-administered electronic questionnaire covering demographics, time, awareness, factors related DED. Ocular Surface Disease Index (OSDI) used severity Statistical analysis performed using SPSS, significance set at p < 0.05. RESULTS: 67.8%, 19.9% cases being mild, 18% moderate, 29.8% severe. Long use computer screens (77%), fatigue (69.7%), air pollution (68.9%) most commonly reported for Significant associations found between such as female gender (p = 0.003), older 0.049), TV 0.030). Awareness high, 83.1% participants reporting knowledge condition, primarily internet sources healthcare professionals. However, only regular doctor visits, 50.5% cooling drops symptom relief instead artificial tears. CONCLUSION: highly prevalent youth, fatigue, contributing risk. widespread, but healthcare- seeking behavior remains low. Strategies promote early diagnosis, proper treatment, preventive measures are needed reduce burden this population.

Language: Английский

Prevalence of dry eye disease in Spain: a population-based survey (PrevEOS) DOI Creative Commons
J.M. Benítez-del-Castillo,

Bárbara Burgos

The Ocular Surface, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

Citations

2
Perfluorohexyloctane Ophthalmic Solution: A Review in Dry Eye Disease DOI

Amy Zhuang-Yan,

Yahiya Y. Syed

Drugs, Journal Year: 2024, Volume and Issue: 84(4), P. 441 - 448

Published: March 30, 2024

Language: Английский

Citations

7
Leveraging large language models to improve patient education on dry eye disease DOI
Qais A. Dihan, Andrew D. Brown, Muhammad Z. Chauhan

et al.

Eye, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 16, 2024

Language: Английский

Citations

4
Influence of Neutral and Cationic Phytoglycogen Nanoparticles on Cartilage and Ocular Lubrication DOI Creative Commons

Nikola R. Mazarevica,

Yong Chen, Ke Ren

et al.

Biosurface and Biotribology, Journal Year: 2025, Volume and Issue: 11(1)

Published: Jan. 1, 2025

ABSTRACT Compromised hydration and biolubrication leads to untreatable disorders like osteoarthritis (OA), dry eye disease (DED) mouth (xerostomia). Only symptomatic treatment is possible through bioactive molecules. This study aims investigate the properties of natural modified phytoglycogen nanoparticles (PGNPs) which have shown superlubricious behaviour at mica‐mica sliding interface. PGNPs were cationised (CPGNPs) by modifying hydroxyl groups into quaternary amine groups. Dynamic light scattering (DLS) was used characterise size zeta‐potential both PGNPs. The quartz crystal microbalance with dissipation (QCM‐D) their adhesion collagen type II mucin. tribological studied using polydimethylsiloxane (PDMS)‐glass system, cartilage‐glass (synovial) eye‐eyelid (ocular) systems. CPGNPs adhered better than on synovial ocular surfaces. Both particle types showed good lubrication for cartilage but no differences between in system observed. Overall, observed lubricating indicating great potential towards a implementation osteoarthritis.

Language: Английский

Citations

0
Three-Dimensional Printing for Accessible and Personalized Ophthalmic Care: A Review DOI Open Access
Mina Mina,

Ajay Kumar Goel,

Fady Mina

et al.

Journal of Clinical & Translational Ophthalmology, Journal Year: 2025, Volume and Issue: 3(2), P. 6 - 6

Published: March 26, 2025

Over 2.2 billion people across the globe face significant barriers to accessing essential ophthalmic care, with elderly, rural, and refugee populations being disproportionately affected, deepening existing disparities in eye care. Three-dimensional printing is a novel technology that has potential transform field improve access by alleviating many patient-specific barriers. This article delves into evolution of 3D within ophthalmology, highlighting its current applications future potential. It explores various techniques numerous biomaterials discussing their effectiveness creating advanced solutions such as bioengineered corneas, ocular prosthetics, innovative treatments for dry syndrome, from punctal plugs lacrimal gland models. Additionally, revolutionized drug delivery systems conditions like glaucoma, retinal diseases, brachytherapy. Whether through printed contact lens-based or polycaprolactone implants biodegrade provide sustained release without adverse effects, these hold immense field. Despite promise, integration clinical practice presents challenges, which addresses alongside strategies overcoming them. By mapping out technological advancements this review offers roadmap enhancing global care accessibility improving patient outcomes on scale.

Language: Английский

Citations

0
Expert Consensus on Pediatric Dry Eye: Insights from a European Delphi Study DOI
Edoardo Villani, Paolo Nucci,

José M. Benítez‐del‐Castillo

et al.

The Ocular Surface, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Citations

0
Assessment of the prevalence and risk factors for dry eye symptoms among Romanian medical students using the ocular surface disease index – a cross-sectional study DOI Creative Commons
Laura Denisa Preoteasa,

D Preoteasa

BMC Ophthalmology, Journal Year: 2024, Volume and Issue: 24(1)

Published: Jan. 5, 2024

Abstract Background This study aims to assess how Romanian medical students suffer from dry eye disease symptoms, establish the prevalence and severity of (DE) symptoms identify potential risk factors. Methods An analytical, cross-sectional was conducted on “Carol Davila” University Medicine, Romania, after final examination period July 2022. The OSDI score (Ocular Surface Disease Index©) applied in an online survey. adopted standards used by other authors, who defined symptomatic DED as greater than 12. chi-square test statistical significance at a cutoff value p < 0.05. predictive model created using linear logistic regression analysis. goodness fit assessed Hosmer-Lemeshow test. When outcome had nominal categorical form, multinomial analysis with normal subjects reference performed. distribution severe type symptomatology across sex categories years analyzed nonparametric (Independent-Samples Kruskal-Wallis Test). Results A total 274 answers were received 81.4% females 18.6% males response rate 35.58%. mean age 22.7 ± 1.66 range between 20 25 old. Using score, we established that overall DE 83.6% (95%CI: 79.6%, 88%), 85.2% 80.5%, 89.8%) 76.5% 65%,88%) males. form most prevalent, regardless year or sex. Increased screen time ( -value 0.05) non-smokers proven which includes explanatory variables (sex, contact lens wearers, smoking, oral contraceptives, time) proved 84.7% predictability for able better predict dependent variable intercept only 0.05). Smoking = 0.002) 0.009) preserved their multinominal well. Conclusions is first report epidemiology among students. revealed high Screen time, although not factor, likely plays role exacerbating disease. information can be inform healthcare policies, occupational health guidelines, implement preventive measures individuals similar high-stress academic professional environments.

Language: Английский

Citations

3
Sustainable use of a smartphone and regulatory needs DOI Creative Commons
Martin Kögler, Katharina Paulick, Jürgen Scheffran

et al.

Sustainable Development, Journal Year: 2024, Volume and Issue: unknown

Published: April 29, 2024

Abstract The significance of information and communication technologies (ICT) for the Paris Climate Agreement is continuously increasing because its growing energy consumption. Here we examine question smartphone extend investigation to more aspects sustainability. Critical issues are identified ten UN Sustainable Development Goals. Measurements consumption show that a significant savings potential can be unlocked by reducing data outflow large amount personal stored in centers. Main discrepancies also traced oligopolistic market structure operating systems (OSs), messenger services, social media apps. Technical means sustainable use suggested as alternative OSs, channels Fediverse, well free open‐source software. Finally, societal conditions emphasized make OSs apps diverse so generally prevail.

Language: Английский

Citations

3
Synthesis of Benzofuran-6-carboxylic Acid, an Intermediate of Lifitegrast with Low-Carbon Footprints DOI

Vishal M. Zade,

Paresh R. Athawale,

Harishankar Kopperi

et al.

ACS Sustainable Chemistry & Engineering, Journal Year: 2024, Volume and Issue: 12(42), P. 15671 - 15681

Published: Oct. 7, 2024

Scalable and sustainable synthesis of key fragments with a low environmental impact is crucial for API synthesis. Herein, we report the benzofuran-6-carboxylic acid, fragment drug lifitegrast used treating keratoconjunctivitis sicca. Unlike existing routes, this features transition metal-free, three-step protocol using general reagents. The scalability process was successfully demonstrated on 100 g scale. target compound obtained in pure form (98.2% HPLC purity) without chromatographic purification. methods avoid use metals cryogenic temperatures employed known routes. A life cycle analysis comparison current routes indicated that present route leaves smaller carbon footprint. By metal-free base catalyst, significant benefits, mainly CO2 emission savings, enhanced human health quality, lower mineral depletion, affirming sustainability lowering reaction steps. Designing chemical syntheses alternative pathways reduces input, supports chemists decision-making, addresses to low-carbon processes products.

Language: Английский

Citations

3
Effectiveness of a New Active Tear Substitute Containing 0.2% Hyaluronic Acid and 0.001% Hydrocortisone on Signs and Symptoms of Dry Eye Disease by Means of Low- and High-Tech Assessments DOI Creative Commons
Paolo Fogagnolo, Giuseppe Giannaccare, Rita Mencucci

et al.

Ophthalmology and Therapy, Journal Year: 2023, Volume and Issue: 13(1), P. 251 - 266

Published: Nov. 10, 2023

An innovative eye drops formulation containing 0.2% hyaluronic acid and a low concentration of hydrocortisone (0.001%; hereafter HALH) has been recently placed on the market (Idroflog

Language: Английский

Citations

7