Life Sciences,
Год журнала:
2020,
Номер
256, С. 117962 - 117962
Опубликована: Июнь 11, 2020
The
aim
of
the
present
study
was
to
evaluate
oral
resveratrol
effects
associated
with
diet
and
physical
training
changes
on
anthropometric
biochemical
parameters.
25
individuals
aged
from
30
60
years
old;
Body
Mass
Index
(BMI)
≥
kg/m2
were
included
in
study.
Following
primary
evaluation
(anthropometric
clinical),
patients
randomly
divided
into
2
groups:
(1)
Placebo:
Physical
activity
program
+
Diet
Placebo;
(2)
Resveratrol:
Resveratrol
(RVS)
(250
mg/day)
for
three
months.
Anthropometric
parameters
evaluated
at
baseline
after
treatment
period.
main
findings
showed
that
supplementation
improved
total
cholesterol
(TC),
High-density
Lipoprotein
(HDL-c),
Very-low
density
(VLDL-c),
urea,
creatinine
albumin
serum
levels.
These
indicate
this
polyphenol
may
be
an
option
potentiate
beneficial
induced
by
dietary
programs
Metabolic
Syndrome
(MetS)
treatment.
Frontiers in Pharmacology,
Год журнала:
2024,
Номер
15
Опубликована: Апрель 30, 2024
Introduction
Metabolic
syndrome
comprises
a
collection
of
metabolic
disorders
stemming
from
factors
like
genetic
predisposition,
inadequate
nutrition,
stress,
decreased
physical
activity,
aging,
and
ethnicity.
Although
traditional
pharmaceutical
treatments
exist
for
syndrome,
their
limited
popularity
is
attributed
to
high
costs
adverse
effects.
Consequently,
natural
products
with
fewer
side
effects
have
been
explored
managing
this
condition.
This
literature
review
aims
explore
the
role
including
herbs,
botanicals,
vitamins,
minerals,
probiotics,
dietary
supplements
in
syndrome.
Methods
scoping
was
conducted
five
steps,
involving
formulation
research
question,
retrieval
extraction
relevant
studies,
selection
pertinent
organization
information
into
tables,
reporting
results.
Data
collected
various
databases
Embase,
Science
Direct,
PubMed,
Google
Scholar,
Scopus,
Web
Science,
focus
on
studies
published
2010
present,
available
English
full-text
accessibility.
Results
We
identified
1,259
articles,
screened
titles,
abstracts,
full
texts,
ultimately
incorporating
169
articles
(comprising
90
32
trial
6
vitro
38
vivo
1
experimental
article
2
observational
articles).
The
study’s
outcomes
revealed
that
products,
encompassing
plants
derivatives,
vitamins
supplements,
as
well
can
exert
beneficial
influence
by
regulating
blood
sugar,
pressure,
lipid
profiles,
obesity,
abnormal
cholesterol
triglyceride
levels.
Conclusion
current
study
underscores
significance
addressing
it
advisable
conduct
further
extensive
assess
efficacy
these
potentially
integrating
them
treatment
regimens
individuals
Antioxidants,
Год журнала:
2024,
Номер
13(10), С. 1220 - 1220
Опубликована: Окт. 10, 2024
Polyphenols
are
organic
chemical
compounds
naturally
present
in
plants,
renowned
for
their
anti-inflammatory,
antioxidant,
immunomodulatory,
anticancer,
and
cardiovascular
protective
properties.
Their
bioactivity
bioavailability
can
vary
widely
depending
on
the
methods
of
food
processing
interactions
with
gut
microbiome.
These
factors
induce
changes
polyphenols,
affecting
ability
to
achieve
intended
health
benefits.
Thus,
it
is
essential
develop
apply
that
optimize
polyphenol
content
while
maintaining
bioavailability.
This
review
aims
explore
how
various
techniques
affect
quantity,
bioactivity,
as
well
microbiome,
which
may
ultimately
determine
effects.
Antioxidants,
Год журнала:
2019,
Номер
8(3), С. 74 - 74
Опубликована: Март 26, 2019
Studies
in
animal
models
of
diabetes
and
obesity
have
shown
that
resveratrol
mitigates
complications
metabolic
diseases,
beyond
those
resulting
from
oxidative
stress.
Furthermore,
results
obtained
with
cultured
preadipocytes
also
revealed
prolonged
treatment
impairs
adipogenesis.
Considering
the
role
adipocytes
hypertrophy
fat
stores,
keeping
mind
insulin
is
main
trigger
excessive
energy
storage
during
post-prandial
periods,
present
study
aimed
to
investigate
how
short-term
effects
can
limit
glucose
disposal
a
gut-adipose
tissue
axis.
We
found
exhibits
more
potent
inhibitory
capacity
towards
α-glucosidase
than
pancreatic
lipase
activity.
Resveratrol
rapidly
blunts
transport
mature
cells
by
counteracting
effect
insulin-like
lipogenic
agents.
Within
two
hours,
inhibited
incorporation
into
lipids
adipocytes,
which
was
unaffected
membrane
cholesterol
depletion.
Moreover,
comparison
between
invalidated
semicarbazide-sensitive
amine
oxidase
activity
their
control,
or
several
inhibitors,
did
not
indicate
recently
described
interaction
oxidases
involved
its
antilipogenic
effect.
Caffeine
piceatannol,
previously
said
interact
carriers,
inhibit
lipogenesis
whereas
other
antioxidant
phytochemicals
do
reproduce
such
an
This
highlights
diverse
first
steps
accumulation,
indicating
this
natural
molecule
derivatives
deserve
further
studies
develop
potential
anti-obesity
properties.
Life Sciences,
Год журнала:
2020,
Номер
256, С. 117962 - 117962
Опубликована: Июнь 11, 2020
The
aim
of
the
present
study
was
to
evaluate
oral
resveratrol
effects
associated
with
diet
and
physical
training
changes
on
anthropometric
biochemical
parameters.
25
individuals
aged
from
30
60
years
old;
Body
Mass
Index
(BMI)
≥
kg/m2
were
included
in
study.
Following
primary
evaluation
(anthropometric
clinical),
patients
randomly
divided
into
2
groups:
(1)
Placebo:
Physical
activity
program
+
Diet
Placebo;
(2)
Resveratrol:
Resveratrol
(RVS)
(250
mg/day)
for
three
months.
Anthropometric
parameters
evaluated
at
baseline
after
treatment
period.
main
findings
showed
that
supplementation
improved
total
cholesterol
(TC),
High-density
Lipoprotein
(HDL-c),
Very-low
density
(VLDL-c),
urea,
creatinine
albumin
serum
levels.
These
indicate
this
polyphenol
may
be
an
option
potentiate
beneficial
induced
by
dietary
programs
Metabolic
Syndrome
(MetS)
treatment.
