Journal of Medicinal Food,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 6, 2025
Skeletal
muscle
health
is
essential
for
metabolic
homeostasis,
and
dysregulated
apoptosis
in
cells
can
lead
to
wasting
degenerative
diseases.
Although
soybean-derived
peptides
are
known
their
bioactive
properties,
including
antioxidant
anti-apoptotic
effects,
impact
on
regulation
skeletal
remains
underexplored.
This
study
aims
investigate
the
effects
of
low-molecular-weight
soy
peptide
hydrolysate
(SPH)
related
markers
C2C12
myoblasts.
SPH
was
prepared
by
enzymatic
hydrolysis,
its
activities
were
analyzed
through
vitro
assays
(i.e.,
ABTS,
DPPH).
Cellular
studies
used
evaluate
ROS
scavenging
apoptosis.
Results
show
that
enhanced
activity,
reduced
levels,
promoted
cell
proliferation
a
dose-dependent
manner.
notably
decreased
under
oxidative
stress
down-regulating
p53,
c-Caspase-3,
Cyto-c,
while
promoting
HO-1
expression,
likely
via
AMPK
activation.
Importantly,
had
no
significant
inflammation-related
proteins
or
MAPK
These
findings
suggest
may
have
therapeutic
potential
against
intrinsic
pathways,
contributing
maintenance.
Journal of Integrative Plant Biology,
Год журнала:
2023,
Номер
65(2), С. 496 - 525
Опубликована: Янв. 14, 2023
Abstract
With
ongoing
global
climate
change,
water
scarcity‐induced
drought
stress
remains
a
major
threat
to
agricultural
productivity.
Plants
undergo
series
of
physiological
and
morphological
changes
cope
with
stress,
including
stomatal
closure
reduce
transpiration
in
root
architecture
optimize
uptake.
Combined
phenotypic
multi‐omics
studies
have
recently
identified
number
drought‐related
genetic
resources
different
crop
species.
The
functional
dissection
these
genes
using
molecular
techniques
has
enriched
our
understanding
responses
crops
provided
targets
for
enhancing
resistance
drought.
Here,
we
review
recent
advances
the
cloning
analysis
development
technologies
mitigate
production.
Food & Function,
Год журнала:
2022,
Номер
13(24), С. 12510 - 12540
Опубликована: Янв. 1, 2022
This
work
highlights
the
structure–activity
relationship
of
anti-inflammatory
peptides,
estimates
their
in
silico
potential
using
bioactivity
predictors
and
studies
presence
sustainable
protein
sources.
Journal of Agricultural and Food Chemistry,
Год журнала:
2022,
Номер
70(12), С. 3585 - 3595
Опубликована: Март 18, 2022
Chronic
diseases,
including
metabolic
have
become
a
worldwide
public
health
issue.
Research
regarding
the
use
of
bioactive
peptides
or
protein
hydrolysates
derived
from
food,
as
diet-based
strategies
for
prevention
and
mitigation
chronic
has
increased
exponentially
in
past
decades.
Numerous
vitro
vivo
studies
report
efficacy
safety
food-derived
antihypertensive,
anti-inflammatory,
antidiabetic,
antioxidant
agents.
However,
despite
promising
preclinical
results,
an
inadequate
understanding
their
mechanisms
action
pharmacokinetics
restrict
clinical
translation.
Commercialization
can
be
further
hindered
due
to
scarce
information
efficacy,
safety,
bitter
taste,
well
lack
cost-effective
method
production.
This
review
provides
overview
current
evidence
challenges
commercial
applications
alleviation
diseases.
Critical Reviews in Food Science and Nutrition,
Год журнала:
2022,
Номер
63(23), С. 6182 - 6195
Опубликована: Янв. 25, 2022
Human
beings
have
consumed
soybean
as
an
excellent
food
source
for
thousand
years
due
to
its
rich
protein,
fatty
acids,
minerals,
and
fibers.
However,
soybeans
were
recognized
one
of
the
big
eight
allergens
resulting
in
allergic
symptoms
even
could
lead
death.
With
increasing
demand
products,
challenges
caused
by
allergy
need
be
solved
urgently.
This
review
detailly
described
pathogenesis
clinical
characteristics
allergy,
also
advantages
disadvantages
four
different
diagnostic
methods
summarized.
The
major
their
structures
Three
types
including
Type
I,
III,
IV,
which
trigger
reactions
reported
this
review.
Summary
showed
that
double-blind,
placebo-controlled
challenge
is
a
gold
standard
diagnosing
allergy.
processing
techniques
reducing
discussed,
results
concluded
some
novel
such
ultrasound,
cold-plasma
treatment,
potential
application
reduction
allergenicity.
Further,
suggestions
regarding
management
treatment
allergies
addressed
Current Issues in Molecular Biology,
Год журнала:
2024,
Номер
46(5), С. 4203 - 4233
Опубликована: Май 1, 2024
The
global
demand
for
sustainable
and
nutritious
food
sources
has
catalyzed
interest
in
legumes,
known
their
rich
repertoire
of
health-promoting
compounds.
This
review
delves
into
the
diverse
array
bioactive
peptides,
protein
subunits,
isoflavones,
antinutritional
factors,
saponins
found
primary
legume
sources—soybeans,
peas,
chickpeas,
mung
beans.
current
state
research
on
these
compounds
is
critically
evaluated,
with
an
emphasis
potential
health
benefits,
ranging
from
antioxidant
anticancer
properties
to
management
chronic
diseases
such
as
diabetes
hypertension.
extensively
studied
soybean
highlighted
relatively
unexplored
other
legumes
also
included,
pointing
a
significant,
underutilized
resource
developing
health-enhancing
foods.
advocates
future
interdisciplinary
further
unravel
mechanisms
action
explore
synergistic
effects.
ultimate
goal
leverage
full
spectrum
benefits
offered
by
not
only
advance
human
but
contribute
sustainability
systems.
By
providing
comprehensive
overview
nutraceutical
this
manuscript
sets
foundation
investigations
aimed
at
optimizing
use
pursuit
nutritional
security.
Biomolecules,
Год журнала:
2025,
Номер
15(1), С. 88 - 88
Опубликована: Янв. 9, 2025
One
class
of
cosmetic
compounds
that
have
raised
interest
many
experts
is
peptides.
The
search
for
ingredients
with
good
biocompatibility
and
bioactivity
has
led
to
the
use
peptides
in
products.
Peptides
are
novel
active
improve
collagen
synthesis,
enhance
skin
cell
proliferation,
or
decrease
inflammation.
Based
on
their
mechanism
action,
they
can
be
classified
into
signal
peptides,
carrier
neurotransmitter
inhibitor
enzyme
This
review
focuses
main
types
application
field,
underlining
limitations.
most
significant
drawbacks
poor
permeability
through
membranes,
which
limits
delivery
effectiveness.
As
a
result,
this
follows
methods
used
improving
stratum
corneum.
Increasing
peptide
bioavailability
stability
enhanced
desired
site
action
visible
effects
become
central
points
latest
research
due
promising
features.
For
purpose,
several
been
identified
described.
Physical
techniques
include
thermal
ablation
(radiofrequency
laser),
electrical
(electroporation,
iontophoresis),
mechanical
approach
(microneedles),
ultrasounds.
an
alternative,
innovative
formulations
developed
nano-systems
such
as
liposomes,
niosomes,
ethosomes,
nanoemulsions,
other
nanomaterials
reduce
irritation
product
purpose
provide
information
regarding
these
noteworthy
molecules
reasoning
behind
formulations.
Frontiers in Nutrition,
Год журнала:
2023,
Номер
10
Опубликована: Июнь 15, 2023
Soybeans
are
rich
in
proteins
and
phytochemicals
such
as
isoflavones
phenolic
compounds.
It
is
an
excellent
source
of
peptides
with
numerous
biological
functions,
including
anti-inflammatory,
anticancer,
antidiabetic
activities.
Soy
bioactive
small
building
blocks
that
released
after
fermentation
or
gastrointestinal
digestion
well
by
food
processing
through
enzymatic
hydrolysis,
often
combination
novel
techniques
(i.e.,
microwave,
ultrasound,
high-pressure
homogenization),
which
associated
health
benefits.
Various
studies
have
reported
the
potential
benefits
soybean-derived
functional
peptides,
made
them
a
great
substitute
for
many
chemical-based
elements
foods
pharmaceutical
products
healthy
lifestyle.
This
review
provides
unprecedented
up-to-date
insights
into
role
soybean
various
diseases
metabolic
disorders,
ranging
from
diabetes
hypertension
to
neurodegenerative
disorders
viral
infections
mechanisms
were
discussed.
In
addition,
we
discuss
all
known
techniques,
conventional
emerging
approaches,
prediction
active
peptides.
Finally,
real-life
applications
entities
