Advancing Sustainability in Modern Polymer Processing: Strategies for Waste Resource Recovery and Circular Economy Integration

Polymers, Год журнала: 2025, Номер 17(4), С. 522 - 522

Опубликована: Фев. 17, 2025

By the late 1970s, plastics had emerged as most widely used materials globally. The discovery, development, and processing of diverse polymeric have profoundly shaped modern life driven expansion numerous industries. Given widespread interest in utilization these materials, it has become increasingly imperative to design their cycles from outset. This approach aims maximize utility while minimizing environmental footprint. review identify analyze key challenges polymer applicable both additive formative manufacturing methods, emphasizing relationship between recycling within framework sustainability. Modern techniques play a crucial role enhancing sustainability products by improving potential (with consideration type, source, additives), cost-effectiveness, carbon footprint, properties such durability, lifespan, performance, impact. It will also explore concept circular economy its integration into including extrusion, injection molding, 3D printing. Additionally, current methods are analyzed with respect effectiveness, sustainability, compatibility original materials. Moreover, discussion emphasizes benefits compared linear one exploring concepts closed-loop open-loop systems, along applications depending on material initial method employed. To ensure that humanity continues benefit striving for waste-free environment, is essential integrate principles sustainable development very beginning.

Язык: Английский

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3D PRINTING TECHNOLOGY IN MICRONEEDLES: AN EMERGING ERA IN TRANSDERMAL DRUG DELIVERY

Hybrid Advances, Год журнала: 2025, Номер unknown, С. 100447 - 100447

Опубликована: Март 1, 2025

Язык: Английский

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Advancements in transdermal drug delivery using microneedles: technological and material perspective

Опубликована: Апрель 7, 2025

Язык: Английский

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Hydrogel-Forming Microneedles in the Management of Dermal Disorders Through a Non-Invasive Process: A Review

Gels, Год журнала: 2024, Номер 10(11), С. 719 - 719

Опубликована: Ноя. 7, 2024

Microneedle (MN) technology has emerged as a promising approach for delivering therapeutic agents to the skin, offering significant potential in treating various dermal conditions. Among these technologies, hydrogel-forming microneedles (HFMNs) represent transformative advancement management of diseases through non-invasive drug delivery. These innovative devices consist micrometer-sized needles made native or crosslinked hydrophilic polymers, capable penetrating stratum corneum without damaging underlying tissues. Upon insertion, HFMNs rapidly absorb interstitial fluid, swelling form hydrogel conduit that enables efficient transport directly into microcirculation. The nature enhances patient compliance by eliminating pain and discomfort associated with traditional hypodermic needles. This allows delivery wide range drugs, including macromolecules biomacromolecules, which are often difficult administer dermally due their size polarity. Moreover, provide controlled regulated release profiles, enabling sustained effects while minimizing systemic side effects. Additionally, can be used both real-time fluid monitoring, valuable insights disease states treatment responses. dual functionality positions versatile dermatology tool effectively addressing complications. review explores use polymeric biomaterials HFMN fabrication application major disorders, such acne, psoriasis, other skin Furthermore, highlights MN-based treatments, underscoring reduce improve adherence, supported recent literature.

Язык: Английский

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Dissolving microneedles for brain delivery: Recent advances and challenges

Drug Discovery Today, Год журнала: 2025, Номер unknown, С. 104330 - 104330

Опубликована: Март 1, 2025

Язык: Английский

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Nanomaterial-Enhanced Microneedles: Emerging Therapies for Diabetes and Obesity

Pharmaceutics, Год журнала: 2024, Номер 16(10), С. 1344 - 1344

Опубликована: Окт. 21, 2024

Drug delivery systems (DDS) have improved therapeutic agent administration by enhancing efficacy and patient compliance while minimizing side effects. They enable targeted delivery, controlled release, bioavailability. Transdermal drug (TDDS) offer non-invasive medication evolved to include methods such as chemical enhancers, iontophoresis, microneedles (MN), nanocarriers. MN technology provides innovative solutions for chronic metabolic diseases like diabetes obesity using various types. For management, MNs continuous glucose monitoring, diabetic wound healing, painless insulin delivery. treatment, provide sustained transdermal of anti-obesity drugs or nanoparticles (NPs). Hybrid integrating wearable sensors smart materials enhance treatment effectiveness management. Nanotechnology has advanced nano-scaled liposomes polymeric NPs with MNs. In glucose-responsive facilitate At the same time, lipid nanocarriers in dissolving extended release stability absorption disorder therapies. DDS are advancing toward personalized treatments enhanced nanomaterials. These approaches can outcomes through precise real-time monitoring. However, widespread implementation faces challenges ensuring biocompatibility, improving technologies, scaling production, obtaining regulatory approval. This review will present recent advances developing applying nanomaterial-enhanced management also discussing challenges, limitations, future perspectives these DDS.

Язык: Английский

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Emerging Technological Advancement for Chronic Wound Treatment and Their Role in Accelerating Wound Healing

ACS Applied Bio Materials, Год журнала: 2024, Номер 7(11), С. 7101 - 7132

Опубликована: Окт. 28, 2024

Chronic wounds are a major healthcare burden and may severely affect the social, mental, economic status of patients. Any impairment in wound healing stages due to underlying factors leads prolonged time subsequently chronic wounds. Traditional approaches for treatment include dressing free local therapy, tissue engineering based scaffold therapies. However, traditional therapies need improvisation have been advanced through breakthrough technologies. The present review spans further gives an extensive account advancements Cutting edge technologies, such as 3D printing, which includes inkjet fused deposition modeling, digital light processing, extrusion-based microneedle array-based therapies, gene microRNAs (miRNAs) smart dressings real monitoring conditions assessment pH, temperature, oxygen, moisture, metabolites, their use planning better strategies discussed detail. future direction treatments that will aid lowering caused

Язык: Английский

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Microneedle sensors for dermal interstitial fluid analysis

Med-X, Год журнала: 2024, Номер 2(1)

Опубликована: Окт. 1, 2024

Язык: Английский

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Low-cost fabrication of digital light processing 3D printed conical microneedles for biomedical applications

Applied Materials Today, Год журнала: 2024, Номер 41, С. 102482 - 102482

Опубликована: Окт. 28, 2024

Язык: Английский

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Microneedle-based arrays – breakthrough strategy for the treatment of bacterial and fungal skin infections

Microbes and Infection, Год журнала: 2024, Номер unknown, С. 105426 - 105426

Опубликована: Сен. 1, 2024

Язык: Английский

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