Materials Science and Engineering R Reports, Journal Year: 2025, Volume and Issue: 165, P. 101015 - 101015
Published: May 14, 2025
Language: Английский
Materials Science and Engineering R Reports, Journal Year: 2025, Volume and Issue: 165, P. 101015 - 101015
Published: May 14, 2025
Language: Английский
Polymers, Journal Year: 2025, Volume and Issue: 17(4), P. 522 - 522
Published: Feb. 17, 2025
By the late 1970s, plastics had emerged as most widely used materials globally. The discovery, development, and processing of diverse polymeric have profoundly shaped modern life driven expansion numerous industries. Given widespread interest in utilization these materials, it has become increasingly imperative to design their cycles from outset. This approach aims maximize utility while minimizing environmental footprint. review identify analyze key challenges polymer applicable both additive formative manufacturing methods, emphasizing relationship between recycling within framework sustainability. Modern techniques play a crucial role enhancing sustainability products by improving potential (with consideration type, source, additives), cost-effectiveness, carbon footprint, properties such durability, lifespan, performance, impact. It will also explore concept circular economy its integration into including extrusion, injection molding, 3D printing. Additionally, current methods are analyzed with respect effectiveness, sustainability, compatibility original materials. Moreover, discussion emphasizes benefits compared linear one exploring concepts closed-loop open-loop systems, along applications depending on material initial method employed. To ensure that humanity continues benefit striving for waste-free environment, is essential integrate principles sustainable development very beginning.
Language: Английский
Citations
3Hybrid Advances, Journal Year: 2025, Volume and Issue: unknown, P. 100447 - 100447
Published: March 1, 2025
Language: Английский
Citations
1Published: April 7, 2025
Language: Английский
Citations
1Gels, Journal Year: 2024, Volume and Issue: 10(11), P. 719 - 719
Published: Nov. 7, 2024
Microneedle (MN) technology has emerged as a promising approach for delivering therapeutic agents to the skin, offering significant potential in treating various dermal conditions. Among these technologies, hydrogel-forming microneedles (HFMNs) represent transformative advancement management of diseases through non-invasive drug delivery. These innovative devices consist micrometer-sized needles made native or crosslinked hydrophilic polymers, capable penetrating stratum corneum without damaging underlying tissues. Upon insertion, HFMNs rapidly absorb interstitial fluid, swelling form hydrogel conduit that enables efficient transport directly into microcirculation. The nature enhances patient compliance by eliminating pain and discomfort associated with traditional hypodermic needles. This allows delivery wide range drugs, including macromolecules biomacromolecules, which are often difficult administer dermally due their size polarity. Moreover, provide controlled regulated release profiles, enabling sustained effects while minimizing systemic side effects. Additionally, can be used both real-time fluid monitoring, valuable insights disease states treatment responses. dual functionality positions versatile dermatology tool effectively addressing complications. review explores use polymeric biomaterials HFMN fabrication application major disorders, such acne, psoriasis, other skin Furthermore, highlights MN-based treatments, underscoring reduce improve adherence, supported recent literature.
Language: Английский
Citations
7Drug Discovery Today, Journal Year: 2025, Volume and Issue: unknown, P. 104330 - 104330
Published: March 1, 2025
Language: Английский
Citations
1Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(10), P. 1344 - 1344
Published: Oct. 21, 2024
Drug delivery systems (DDS) have improved therapeutic agent administration by enhancing efficacy and patient compliance while minimizing side effects. They enable targeted delivery, controlled release, bioavailability. Transdermal drug (TDDS) offer non-invasive medication evolved to include methods such as chemical enhancers, iontophoresis, microneedles (MN), nanocarriers. MN technology provides innovative solutions for chronic metabolic diseases like diabetes obesity using various types. For management, MNs continuous glucose monitoring, diabetic wound healing, painless insulin delivery. treatment, provide sustained transdermal of anti-obesity drugs or nanoparticles (NPs). Hybrid integrating wearable sensors smart materials enhance treatment effectiveness management. Nanotechnology has advanced nano-scaled liposomes polymeric NPs with MNs. In glucose-responsive facilitate At the same time, lipid nanocarriers in dissolving extended release stability absorption disorder therapies. DDS are advancing toward personalized treatments enhanced nanomaterials. These approaches can outcomes through precise real-time monitoring. However, widespread implementation faces challenges ensuring biocompatibility, improving technologies, scaling production, obtaining regulatory approval. This review will present recent advances developing applying nanomaterial-enhanced management also discussing challenges, limitations, future perspectives these DDS.
Language: Английский
Citations
6ACS Applied Bio Materials, Journal Year: 2024, Volume and Issue: 7(11), P. 7101 - 7132
Published: Oct. 28, 2024
Chronic wounds are a major healthcare burden and may severely affect the social, mental, economic status of patients. Any impairment in wound healing stages due to underlying factors leads prolonged time subsequently chronic wounds. Traditional approaches for treatment include dressing free local therapy, tissue engineering based scaffold therapies. However, traditional therapies need improvisation have been advanced through breakthrough technologies. The present review spans further gives an extensive account advancements Cutting edge technologies, such as 3D printing, which includes inkjet fused deposition modeling, digital light processing, extrusion-based microneedle array-based therapies, gene microRNAs (miRNAs) smart dressings real monitoring conditions assessment pH, temperature, oxygen, moisture, metabolites, their use planning better strategies discussed detail. future direction treatments that will aid lowering caused
Language: Английский
Citations
5Med-X, Journal Year: 2024, Volume and Issue: 2(1)
Published: Oct. 1, 2024
Language: Английский
Citations
4Applied Materials Today, Journal Year: 2024, Volume and Issue: 41, P. 102482 - 102482
Published: Oct. 28, 2024
Language: Английский
Citations
4Microbes and Infection, Journal Year: 2024, Volume and Issue: unknown, P. 105426 - 105426
Published: Sept. 1, 2024
Language: Английский
Citations
3