Biological platforms for the production of antimicrobial peptides: Bacterial, yeast, and cell-free systems DOI
Juan C. Cruz, Luis H. Reyes

Elsevier eBooks, Год журнала: 2025, Номер unknown, С. 131 - 163

Опубликована: Янв. 1, 2025

Язык: Английский

Microbial cellulase production and its potential application for textile industries DOI Creative Commons
Gamachis Korsa, Rocktotpal Konwarh, Chandran Masi

и другие.

Annals of Microbiology, Год журнала: 2023, Номер 73(1)

Опубликована: Апрель 10, 2023

Abstract Purpose The textile industry’s previous chemical use resulted in thousands of practical particulate emissions, such as machine component damage and drainage system blockage, both which have implications. Enzyme-based processing is cost-effective, environmentally friendly, non-hazardous, water-saving. purpose this review to give evidence on the potential activity microbial cellulase industry, mostly confined realm research. Methods This was progressive by considering peer-reviewed papers linked production, its prospective application for industries appraised produced develop assessment. Articles were divided into two categories based results trustworthy educational journals: methods used produce diversity microorganisms through fermentation processes approaches microbes fermentation. Submerged (SMF) solid-state (SSF) techniques are currently being meet industrial demand production bio industry. Results Microbial vital increasing day due no side effect environment human health becoming increasingly important. In conventional processing, gray cloth subjected a series treatments that involved breaking dye molecule’s amino group with Cl − , started accelerated dye(-resistant) bond cracking. A enzyme primarily derived from variety species found various ecological settings biotextile/bio-based product technology future needs applications. Conclusion Cellulase has been advantages cellulose-based textiles, well quality enhancement fabric maintenance over traditional approaches. Cellulase’s role industry chosen an appropriate sound solution long healthy lifestyle.

Язык: Английский

Процитировано

54

Unlocking the magic in mycelium: Using synthetic biology to optimize filamentous fungi for biomanufacturing and sustainability DOI Creative Commons
Charles Jo, Jing Zhang, Jenny M. Tam

и другие.

Materials Today Bio, Год журнала: 2023, Номер 19, С. 100560 - 100560

Опубликована: Янв. 21, 2023

Filamentous fungi drive carbon and nutrient cycling across our global ecosystems, through its interactions with growing decaying flora their constituent microbiomes. The remarkable metabolic diversity, secretion ability, fiber-like mycelial structure that have evolved in filamentous been increasingly exploited commercial operations. industrial potential of fermentation ranges from the discovery bioproduction enzymes bioactive compounds, decarbonization food material production, to environmental remediation enhanced agricultural production. Despite fundamental impact ecology biotechnology, molds mushrooms not, to-date, significantly intersected synthetic biology ways comparable other cell factories (e.g. Escherichia coli,Saccharomyces cerevisiae, Komagataella phaffii). In this review, we summarize a suite computational tools for mining, engineering optimization as chassis. A combination methods genetic engineering, mutagenesis, experimental evolution, modeling can be used address strain development bottlenecks established emerging industries. These include slow mycelium growth rate, low production yields, non-optimal alternative feedstocks, difficulties downstream purification. scope biomanufacturing, then detail previous efforts improving key by targeting protein processing pathways, hyphae morphogenesis, transcriptional control. Bringing practices into hidden world will serve expand limited panel host organisms allow commercially-feasible environmentally-sustainable enzymes, chemicals, therapeutics, foods, materials future.

Язык: Английский

Процитировано

46

Alternative Protein Sources and Novel Foods: Benefits, Food Applications and Safety Issues DOI Open Access
Laura Quintieri, Chiara Nitride, Elisabetta De Angelis

и другие.

Nutrients, Год журнала: 2023, Номер 15(6), С. 1509 - 1509

Опубликована: Март 21, 2023

The increasing size of the human population and shortage highly valuable proteinaceous ingredients has prompted international community to scout for new, sustainable, natural protein resources from invertebrates (e.g., insects) underutilized legume crops, unexploited terrestrial aquatic weeds, fungi. Insect proteins are known their nutritional value, being rich in with a good balance essential amino acids source fatty trace elements. Unconventional crops were found nutritional, phytochemical, therapeutic properties, showing excellent abilities survive extreme environmental conditions. This review evaluates recent state fungi, insects intended as alternative sources, ingredient production incorporation food products, including formulations functional characteristics plant-based edible insect novel foods. Emphasis is also placed on safety issues due presence anti-nutritional factors allergenic and/or legumes. biological activities hydrolysates different sources reviewed, along bioactive peptides displaying antihypertensive, antioxidant, antidiabetic, antimicrobial activity. Due healthy properties these foods high abundance phytochemicals, more consumers expected turn vegetarianism or veganism future, demand such products will be challenge future.

Язык: Английский

Процитировано

42

Fungal mycelium as leather alternative: A sustainable biogenic material for the fashion industry DOI Creative Commons
Ayodeji Amobonye, Japareng Lalung, Mukesh Kumar Awasthi

и другие.

Sustainable materials and technologies, Год журнала: 2023, Номер 38, С. e00724 - e00724

Опубликована: Сен. 23, 2023

The global leather industry has been at the receiving end of various environmental and ethical backlash as it mainly relies on animal agriculture which contributes to deforestation, greenhouse gas emissions, welfare concerns. In addition, processing hides into generates a huge amount toxic chemicals, ultimately get released environment. Thus, growing concern for sustainability led exploration alternative materials conventional animal- based leather. this regard, application fungal alternatives in material technology is gaining traction because its high biodegradability, biocompatibility, renewability, well affordable carbon-neutral growth processes. Fungal have found possess significant mechanical physical properties, thanks interwoven hyphal network mycelium, antimicrobial activities ascribed their bioactive metabolites. Various species, including those from Agaricus, Fomes, Ganoderma, Phellinus, Pleutorus genera, are currently being investigated potential area. This review, therefore, attempts gain insights recent advances scientific research real-world applications fungal-derived like materials. It makes compelling case sustainable discusses morphology-property relationship mycelium driving innovation. Additionally, current methods major players substitute presented. paper also brings attention challenges facing full deployment substitutes proposes solutions with aim encouraging further resource mobilization acceptance renewable substitute.

Язык: Английский

Процитировано

41

Current trends, limitations and future research in the fungi? DOI Creative Commons
Kevin D. Hyde, Petr Baldrián, Yanpeng Chen

и другие.

Fungal Diversity, Год журнала: 2024, Номер 125(1), С. 1 - 71

Опубликована: Март 20, 2024

Abstract The field of mycology has grown from an underappreciated subset botany, to a valuable, modern scientific discipline. As this study grown, there have been significant contributions science, technology, and industry, highlighting the value fungi in era. This paper looks at current research, along with existing limitations, suggests future areas where scientists can focus their efforts, mycology. We show how become important emerging diseases medical discuss trends potential drug novel compound discovery. explore phylogenomics, its potential, outcomes address question phylogenomics be applied fungal ecology. In addition, functional genomics studies are discussed importance unravelling intricate mechanisms underlying behaviour, interactions, adaptations, paving way for comprehensive understanding biology. look research building materials, they used as carbon sinks, biocircular economies. numbers always great interest often written about estimates varied greatly. Thus, we needs order obtain more reliable estimates. aspects machine learning (AI) it mycological research. Plant pathogens affecting food production systems on global scale, such, needed area, particularly disease detection. latest data High Throughput Sequencing if still gaining new knowledge same rate before. A review nanotechnology is provided addressed. Arbuscular Mycorrhizal Fungi addressed acknowledged. Fungal databases becoming important, therefore provide major databases. Edible medicinal huge medicines, especially Asia prospects discussed. Lifestyle changes (e.g., endophytes, pathogens, and/or saprobes) also extremely trend special issue Diversity.

Язык: Английский

Процитировано

28

Harnessing genetic engineering to drive economic bioproduct production in algae DOI Creative Commons
Abhishek Gupta, Kalisa Kang, Ruchi Pathania

и другие.

Frontiers in Bioengineering and Biotechnology, Год журнала: 2024, Номер 12

Опубликована: Янв. 29, 2024

Our reliance on agriculture for sustenance, healthcare, and resources has been essential since the dawn of civilization. However, traditional agricultural practices are no longer adequate to meet demands a burgeoning population amidst climate-driven challenges. Microalgae emerge as beacon hope, offering sustainable renewable source food, animal feed, energy. Their rapid growth rates, adaptability non-arable land non-potable water, diverse bioproduct range, encompassing biofuels nutraceuticals, position them cornerstone future resource management. Furthermore, microalgae’s ability capture carbon aligns with environmental conservation goals. While microalgae offers significant benefits, obstacles in cost-effective biomass production persist, which curtails broader application. This review examines compared other host platforms, highlighting current innovative approaches aimed at overcoming existing barriers. These include range techniques, from gene editing, synthetic promoters, mutagenesis selective breeding metabolic engineering through transcription factors.

Язык: Английский

Процитировано

18

Heterologous protein production in filamentous fungi DOI Creative Commons

Dujuan Liu,

Sandra Garrigues, Ronald P. de Vries

и другие.

Applied Microbiology and Biotechnology, Год журнала: 2023, Номер 107(16), С. 5019 - 5033

Опубликована: Июль 5, 2023

Abstract Filamentous fungi are able to produce a wide range of valuable proteins and enzymes for many industrial applications. Recent advances in fungal genomics experimental technologies rapidly changing the approaches development use filamentous as hosts production both homologous heterologous proteins. In this review, we highlight benefits challenges using We review various techniques commonly employed improve protein fungi, such strong inducible promoters, codon optimization, more efficient signal peptides secretion, carrier proteins, engineering glycosylation sites, regulation unfolded response endoplasmic reticulum associated degradation, optimization intracellular transport process, unconventional construction protease-deficient strains. Key points • This updates knowledge on fungi. Several cell factories potential candidates discussed. Insights into improving gene expression given.

Язык: Английский

Процитировано

32

Fungal strain improvement for efficient cellulase production and lignocellulosic biorefinery: Current status and future prospects DOI
Jie Yang,

Hou-Ru Yue,

Li-Ya Pan

и другие.

Bioresource Technology, Год журнала: 2023, Номер 385, С. 129449 - 129449

Опубликована: Июль 4, 2023

Язык: Английский

Процитировано

30

Strategies for the Development of Industrial Fungal Producing Strains DOI Creative Commons
Sonia Salazar-Cerezo, Ronald P. de Vries, Sandra Garrigues

и другие.

Journal of Fungi, Год журнала: 2023, Номер 9(8), С. 834 - 834

Опубликована: Авг. 8, 2023

The use of microorganisms in industry has enabled the (over)production various compounds (e.g., primary and secondary metabolites, proteins enzymes) that are relevant for production antibiotics, food, beverages, cosmetics, chemicals biofuels, among others. Industrial strains commonly obtained by conventional (non-GMO) strain improvement strategies random screening selection. However, recombinant DNA technology made it possible to improve microbial adding, deleting or modifying specific genes. Techniques such as genetic engineering genome editing contributing development industrial strains. Nevertheless, there is still significant room further improvement. In this review, we will focus on classical recent methods, tools technologies used fungal with potential be applied at an scale. Additionally, functional genomics, transcriptomics, proteomics metabolomics together implementation manipulation techniques expression discussed.

Язык: Английский

Процитировано

22

Unveiling the Role of Hydrolytic Enzymes from Soil Biocontrol Bacteria in Sustainable Phytopathogen Management DOI Creative Commons
Roohallah Saberi Riseh,

Masoumeh Vatankhah,

Mohadeseh Hassanisaadi

и другие.

Frontiers in Bioscience-Landmark, Год журнала: 2024, Номер 29(3)

Опубликована: Март 15, 2024

Background: Phytopathogens, encompassing fungi, bacteria, viruses, and nematodes, pose a significant threat to the agricultural industry by causing substantial economic losses through severe plant diseases. The excessive use of synthetic fungicides combat phytopathogens has raised environmental human health concerns. Results: Consequently, there is an increasing demand for safe environmentally friendly biopesticides align with consumer preferences uncontaminated food. One particularly promising alternative involves harnessing biocontrol bacteria that produce extracellular hydrolytic enzymes. These enzymes serve effectively manage while concurrently fostering sustainable protection. Among pivotal generated are chitinase, cellulase, protease, lipase, glucanase, amylase. exert their influence breaking down cell wall, proteins, DNA phytopathogens, thereby establishing dependable method biocontrol. Conclusions: Recognizing critical role these in biocontrol, this review seeks delve into primary functions, contribution protection, mechanisms action. Through exploration potential presented enzymatic mechanisms, we can discern effective conscious strategies managing agriculture.

Язык: Английский

Процитировано

14