Applied Sciences,
Год журнала:
2025,
Номер
15(7), С. 3465 - 3465
Опубликована: Март 21, 2025
Wild-simulated
ginseng
(WSG,
Panax
C.A.
Meyer)
is
the
most
important
medicinal
plant
naturally
cultivated
in
forestry
environment.
The
growth
and
active
component
content
of
WSG
can
be
influenced
by
various
environmental
factors,
such
as
climate
conditions,
physiognomy,
soil
properties,
bacterial
structure.
aim
this
study
was
to
investigate
relationship
between
characteristics
community
living
a
rhizosphere
Experimental
subjects
were
7-
13-year-old
central
region
(Yeongju)
Korea.
WSG,
divided
into
aerial
parts,
root
weight
measured.
Rhizome
length
significantly
higher
for
while
number
rootlets
7-year-old
WSG.
As
result
analyzing
communities
cultivation
sites
using
next-generation
sequencing
(NGS),
Proteobacteria
Holophagae
found
dominant
species
phylum
level
class
level,
respectively.
positively
correlated
with
Bacteroidetes
at
but
it
negatively
Thermoleophilia
Gemmatimonadetes
level.
Pedospharae
showed
negative
correlation
leaflets
petiole
length,
Clostridia
positive
rootlets.
might
vary
depending
on
environment
which
cultivated.
It
especially
affected
properties
communities.
Therefore,
future
studies,
will
necessary
isolate
identify
microorganisms
then
confirm
their
growth-promoting
effects
Molecules,
Год журнала:
2020,
Номер
25(19), С. 4390 - 4390
Опубликована: Сен. 24, 2020
Ginseng
is
a
traditional
medicinal
herb
commonly
consumed
world-wide
owing
to
its
unique
family
of
saponins
called
ginsenosides.
The
absorption
and
bioavailability
ginsenosides
mainly
depend
on
an
individual’s
gastrointestinal
bioconversion
abilities.
There
need
improve
ginseng
processing
predictably
increase
the
pharmacologically
active
Various
types
ginseng,
such
as
fresh,
white,
steamed,
acid-processed,
fermented
ginsengs,
are
available.
various
methods
produce
range
ginsenoside
compositions
with
diverse
pharmacological
properties.
This
review
intended
summarize
properties
found
in
different
Panax
species
well
methods.
sugar
moiety
attached
C–3,
C–6,
or
C–20
deglycosylated
minor
ginsenosides,
Rb1,
Rb2,
Rc,
Rd→Rg3,
F2,
Rh2;
Re,
Rf→Rg1,
Rg2,
F1,
Rh1.
malonyl-Rb1,
Rd
were
demalonylated
into
by
dehydration.
Dehydration
also
produces
Rg3→Rk1,
Rg5,
Rz1;
Rh2→Rk2,
Rh3;
Rh1→Rh4,
Rk3;
Rg2→Rg6,
F4;
Rs3→Rs4,
Rs5;
Rf→Rg9,
Rg10.
Acetylation
several
may
generate
acetylated
Rk1,
Rh4,
Rk3,
Rs4,
Rs5,
Rs6,
Rs7.
Acid
Rh1→Rk3,
Rh4;
Rh2→Rk1,
Rg5;
Rg3→Rk2,
Rf,
Rg2→F1,
Rh1,
Rf2,
Rf3,
Rg6,
F4,
Rg9.
Alkaline
Rh16,
Rh3,
ginsenoslaloside-I,
20(S)-ginsenoside-Rh1-60-acetate,
20(R)-ginsenoside
Rh19,
zingibroside-R1
through
hydrolysis,
hydration
addition
reactions,
Moreover,
biological
generates
Rg3,
Rh2,
CK,
Mc,
compound
O,
Y
hydrolysis
synthetic
Rd12
Ia
produced
glycosylation.
respect
particular
could
serve
utilization
agricultural
products,
food,
dietary
supplements,
health
medicines,
spur
future
development
novel
highly
functional
products
combination
Journal of Ginseng Research,
Год журнала:
2022,
Номер
47(3), С. 359 - 365
Опубликована: Март 23, 2022
Ginseng
was
the
most
revered
of
herbs
in
ancient
times
China,
Korea,
Japan,
America.
discovered
over
5000
years
ago
mountains
Manchuria,
China.
References
to
ginseng
are
found
books
dating
back
more
than
two
millennia.
It
is
by
Chinese
people
as
it
considered
a
herb
for
everything
use
and
therefore
wide
range
diseases
(currently
its
Latin
name
derived
from
Greek
panacea,
meanings,
that
is,
everything).
So,
used
exclusively
Emperor's,
they
were
willing
pay
price
without
problems.
Increasing
fame,
brought
flourishing
international
trade
allowed
Korea
supply
China
with
silk
medicines
exchange
wild
later
along
what
grows
Molecules,
Год журнала:
2023,
Номер
28(9), С. 3863 - 3863
Опубликована: Май 3, 2023
Ginseng,
a
medicinal
plant
of
the
genus
Panax,
boasts
rich
historical
record
usage
that
dates
back
to
Paleolithic
period.
This
botanical
is
extensively
acknowledged
and
consumed
in
Eastern
countries
for
its
therapeutic
properties,
and,
Western
countries,
it
becoming
increasingly
popular
as
remedy
fatigue
asthenia.
review
provides
an
update
on
current
research
pertaining
ginseng
isolated
compounds,
namely,
ginsenosides
polysaccharides.
The
primary
focus
three
crucial
pharmacological
activities,
immunomodulation,
anti-inflammatory,
anti-cancer
effects.
encompasses
studies
both
compounds
various
extracts
obtained
from
root,
leaves,
berries.
Polymers,
Год журнала:
2024,
Номер
16(2), С. 231 - 231
Опубликована: Янв. 14, 2024
This
study
evaluated
the
ameliorative
effects
of
Korean-red-ginseng-derived
polysaccharide
(KRG-P)
on
antibiotic-associated
diarrhea
(AAD)
induced
by
administering
lincomycin
in
mice.
Changes
intestinal
barrier
proteins,
microbiome
and
short-chain
fatty
acid
(SCFA)
contents
were
investigated.
Lincomycin
was
orally
administered
for
9
days
to
induce
diarrhea;
subsequently,
100
mg/kg
300
KRG-P
12
days.
The
observed
AAD
group;
further
administration
improved
diarrhea.
Analysis
changes
microbial
flora
mice
revealed
that
harmful
bacterial
(such
as
Proteobacteria)
increased
group,
whereas
beneficial
Firmicutes)
decreased.
However,
resulted
decreased
Proteobacteria
Firmicutes,
supporting
improvement
imbalance
caused
AAD.
Moreover,
an
analysis
SCFAs
(acetic
acid,
propionic
butylic
acid)
caecum
SCFAs’
group
substantially
reduced
but
tended
increase
upon
administration.
Based
these
results,
KRG-P,
which
is
primarily
composed
carbohydrates
can
improve
lincomycin-induced
diarrhea,
likely
owing
recovery
SCFA
content
improving
proteins.
Oxygen,
Год журнала:
2022,
Номер
2(3), С. 246 - 268
Опубликована: Июль 2, 2022
The
rising
prevalence
of
chronic
metabolic
disorders,
such
as
obesity
and
type
2
diabetes,
most
notably
associated
with
cardiovascular
diseases,
has
emerged
a
major
global
health
concern.
Reactive
oxygen
species
(ROS)
play
physiological
functions
by
maintaining
normal
cellular
redox
signaling.
By
contrast,
disturbed
balance
occurring
between
ROS
production
detoxification
reactive
intermediates
results
in
excessive
oxidative
stress.
Oxidative
stress
is
critical
mediator
endothelial
dysfunction
diabetes.
Under
hyperglycemic
condition,
the
antioxidant
enzymes
are
downregulated,
resulting
an
increased
generation
ROS.
Increases
lead
to
impairment
endothelium-dependent
vasodilatations
reducing
NO
bioavailability.
Chronic
treatments
antioxidants
were
reported
prevent
development
diabetic
patients
animals;
however,
beneficial
effects
treatment
combating
vascular
complications
diabetes
remain
controversial
do
not
always
reverse
clinical
settings.
In
this
review,
we
summarize
latest
progress
research
focused
on
role
properties
bioactive
compounds
from
medicinal
plants
food
animal
experiments
studies
provide
insights
for
therapeutic
strategies.
Phytotherapy Research,
Год журнала:
2023,
Номер
37(8), С. 3583 - 3601
Опубликована: Апрель 18, 2023
Oral
decoction
is
widely
applied
in
traditional
Chinese
medicines.
The
polysaccharides
of
promote
the
exposure
small
molecules
and
increase
their
bioavailability.
This
study
mainly
compared
component
activities
total
ginsenosides
(TGS)
ginseng
extract
(GE)
on
immunosuppressed
mice
induced
by
cyclophosphamide.
Thirty-two
were
randomly
divided
into
control,
model,
TGS,
GE
groups.
orally
administered
for
28
days
then
injected
with
cyclophosphamide
last
four
days.
results
analysis
showed
content
12
TGS
(67.21%)
was
higher
than
(2.04%);
17
amino
acids
(1.41%)
lower
(5.36%);
10
monosaccharides
similar
(74.12%)
(76.36%).
animal
that
both
protected
hematopoietic
function
bone
marrow
inhibiting
cell
apoptosis,
recovering
normal
cycle
BM;
maintained
dynamic
balance
between
Th1
Th2
cells;
also
spleen,
thymus,
liver.
Meanwhile,
intestinal
bacteria
increasing
abundance
lactobacillus
decreasing
odoribacter
clostridia_UCG-014.
prevention
effect
superior
to
some
parameters.
In
conclusion,
immune
bioavailability
bioactivity
because
synergistic
plays
an
important
role
protecting
function.
Abstract
Background
The
ginseng
endophyte
Paenibacillus
polymyxa
Pp-7250
(Pp-7250)
has
multifaceted
roles
such
as
preventing
diseases,
promoting
growth,
increasing
ginsenoside
accumulation,
and
degrading
pesticide
residues,
however,
these
effects
still
have
room
for
improvements.
Composite
fungicides
are
an
effective
means
to
improve
the
biocontrol
effect
of
fungicides,
but
in
combination
with
its
symbiotic
bacteria
on
needs
be
further
investigated,
mechanism
action
not
been
elucidated.
In
this
study,
a
series
experiments
was
conducted
elucidate
Bacillus
cereus
co-bacterial
agent
yield
quality
understory
ginseng,
investigate
their
action.
Results
results
indicated
that
P.
B.
(PB)
treatment
improved
yield,
disease
prevention,
degradation.
is
PB
increased
abundance
beneficial
microorganisms,
including
Rhodanobacter
,
Pseudolabrys
Gemmatimonas
Cortinarius
Russula
Paecilomyces
Trechispora
decreased
pathogenic
Ellin6067
Acidibacter
Fusarium
Tetracladium
Alternaria
Ilyonectria
rhizosphere
soil.
agents
enhanced
function
microbial
metabolic
pathways,
biosynthesis
secondary
metabolites,
antibiotics,
amino
acids,
carbon
fixation
pathways
prokaryotes,
DNA
replication,
terpenoid
backbone
biosynthesis,
plant
pathogens
animal
pathogens.
Conclusion
may
potential
promote
resistance
quality,
