Nutritional immunological effects and mechanisms of chemical constituents from the homology of medicine and food

Phytochemistry Reviews, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 2, 2024

Язык: Английский

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An effective and comprehensive optimization strategy for preparing Ginkgo biloba leaf extract enriched in shikimic acid by macroporous resin column chromatography

Phytochemical Analysis, Год журнала: 2024, Номер 35(6), С. 1428 - 1442

Опубликована: Май 9, 2024

Previously reported preparation methods of Ginkgo biloba leaf extract (EGBL) have mainly focused on the enrichment flavonoid glycosides (FG) and terpene trilactones (TT), which led to underutilization G. leaves (GBL).

Язык: Английский

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New insight into the mechanisms of Ginkgo biloba leaves in the treatment of cancer

Phytomedicine, Год журнала: 2023, Номер 122, С. 155088 - 155088

Опубликована: Сен. 14, 2023

Язык: Английский

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Ginkgo biloba: An updated review on pharmacological, ethnobotanical, and phytochemical studies

Pharmacological Research - Modern Chinese Medicine, Год журнала: 2023, Номер 9, С. 100331 - 100331

Опубликована: Ноя. 27, 2023

Ginkgo biloba L. (Ginkgoaceae), known as a "living fossil," has long history of medicinal use. Both its leaves and nuts have been widely prescribed for the treatment various ailments, including pulmonary diseases, alcohol abuse, bladder inflammation, heart lung dysfunction, skin infections. Currently, there are different forms G. available in market, extracts isolated compounds such terpenoids, flavonoids, bioflavonoids, organic acids. Despite significant importance this plant, is lack updated reviews encompassing pharmacology other relevant aspects. Therefore, objective review to collect analyze existing literature on phytochemical, ethnobotanical, pharmacological aspects biloba. Electronic databases PubMed, Embase, Scopus, Google Scholar were searched keywords "Ginkgo biloba" or "ginkgo" combination with "phytochemistry", "ethnobotany", "pharmacology", "nervous system", "cardiovascular", etc. articles. There was no language restriction. Retrieved studies showed that from beneficial activities cerebrovascular, nervous, cardiovascular, endocrine, muscular skeletal, renal, respiratory, digestive, immunity systems. Numerous vitro vivo conducted investigate therapeutic potential improvement diseases. Additionally, substantial body clinical research preparations compounds. However, further investigations, particularly human-controlled trials, recommended determine efficacy safety These trials would provide more robust evidence regarding benefits risks associated use settings.

Язык: Английский

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Function, biosynthesis, and regulation mechanisms of flavonoids in <i>Ginkgo biloba</i>

Fruit Research, Год журнала: 2023, Номер 3(1), С. 0 - 0

Опубликована: Янв. 1, 2023

Ginkgo biloba is an important economic tree species. Due to the abundance of secondary metabolites in tree, extract (GbE) used as a medicine, food supplement, and nutraceutical. Flavonoids are most active components GbE. There increasing evidence that external internal factors affect flavonoid synthesis. The publication G. genome significantly improved functional analyses key genes, transcription factors, non-coding RNAs involved Here, we review progress on understanding mechanisms synthesis accumulation flavonoids biloba. We highlight recent achievements have greatly advanced our functions genes for In addition, discuss novel insights into metabolic regulation network

Язык: Английский

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Use of herbal medication in the perioperative period: Potential adverse drug interactions

Journal of Clinical Anesthesia, Год журнала: 2024, Номер 95, С. 111473 - 111473

Опубликована: Апрель 12, 2024

Use of herbal medications and supplements has experienced immense growth over the last two decades, with retail sales in USA exceeding $13 billion 2021. Since Dietary Supplement Health Education Act (DSHEA) 1994 reduced FDA oversight, these products have become less regulated. Data from 2012 shows 18% U.S. adults used non-vitamin, non-mineral natural products. Prevalence varies regionally, higher use Western states. Among preoperative patients, most commonly included garlic, ginseng, ginkgo, St. John's wort, echinacea. However, 50–70% surgical patients fail to disclose their physicians, discontinue them preoperatively. can interact anesthetic administered during surgery, American Society Anesthesiologists (ASA) Association Nurse Anesthetists (AANA) recommend stopping 1–2 weeks before elective procedures. Potential adverse drug effects related involve coagulation system (e.g., increasing risk perioperative bleeding), cardiovascular arrhythmias, hypotension, hypertension), central nervous sedation, confusion, seizures), pulmonary coughing, bronchospasm), renal diuresis) endocrine-metabolic hepatic dysfunction, altered metabolism drugs). During evaluation, anesthesiologists should inquire about anticipate potential interactions period.

Язык: Английский

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Ginkgo biloba and Its Chemical Components in the Management of Alzheimer’s Disease

The American Journal of Chinese Medicine, Год журнала: 2024, Номер 52(03), С. 625 - 666

Опубликована: Янв. 1, 2024

The pathogenesis of Alzheimer's disease (AD), a degenerative the central nervous system, remains unclear. main manifestations AD include cognitive and behavioral disorders, neuropsychiatric symptoms, neuroinflammation, amyloid plaques, neurofibrillary tangles. However, current drugs for once dementia stage has been reached only treat symptoms do not delay progression, research development targeted have bottleneck. Thus, other treatment options are needed. Bioactive ingredients derived from plants promising therapeutic agents. Specifically,

Язык: Английский

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Extraction, purification, structural characterization, and bioactivities of Ginkgo biloba leave polysaccharides: A review

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 281, С. 136280 - 136280

Опубликована: Окт. 3, 2024

Язык: Английский

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Comparative Analysis of Phytochemical Constituents of Ginkgo Biloba Flowers and Leaves, and Evaluation of Their Biological Activities

Опубликована: Янв. 1, 2025

Ginkgo biloba L, as a Mesozoic relict tree species specialized in China, has attracted much attention for its unique chemical composition and pharmacological properties, most of the research focused on leaves (GBL). Our preliminary found that flowers (GBF) were superior to GBL terms anti-radiation activity, but underlying cause this discrepancy activity remains elusive. Therefore, present study aimed systematically compare nutritional compositions GBF investigate intrinsic mechanism their activities.In study, constituents identified by UPLC-Q-orbitrap HRMS, contents amino acids, fatty inorganic elements, purines, ceramides both determined. Meanwhile, activities exerted through regulation ferroptosis compared, focusing effect inhibiting ferroptosis.The results showed was indeed anti-ferroptosis exhibited more significant inhibitory regulating ferroptosis. Through in-depth analyses both, reveals possible material basis stronger provides theoretical support application nutraceuticals pharmaceuticals, especially development functional drugs with higher health benefits.

Язык: Английский

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Thiol-modified hyaluronic acid and hydroxyl radical-induced oxidation synergistically enhance the gelling capacity of ginkgo seed proteins

Food Chemistry, Год журнала: 2025, Номер 473, С. 143044 - 143044

Опубликована: Янв. 25, 2025

Язык: Английский

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