Unveiling the role of functional foods with emphasis on prebiotics and probiotics in human health: A review

Journal of Functional Foods, Год журнала: 2024, Номер 119, С. 106337 - 106337

Опубликована: Июль 6, 2024

Functional foods particularly prebiotics and probiotics have attracted a lot of attention due to their ability alter gut microbiota an impact on number health disease-related factors, in relation human recent years. are that provide benefits beyond simple sustenance. They contain biologically active ingredients offer additional when consumed regular basis as part balanced diet. Prebiotics, which indigestible fibers specifically promote the growth activity beneficial bacteria, probiotics, live microorganisms upon consumption sufficient amount, shown great promise modifying composition function microbiota. The identified review problem involves clarifying precise impacts immune system function, composition, metabolic health, disease prevention. This emphasizes numerous advantages preserving balance microbiota, boosting immunity, enhancing parameters, reducing risk diseases. also insight advances formulation functional mitigating conditions synergy between prebiotics.

Язык: Английский

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Immunomodulatory Properties of Probiotics and Their Derived Bioactive Compounds

Applied Sciences, Год журнала: 2023, Номер 13(8), С. 4726 - 4726

Опубликована: Апрель 9, 2023

Immune system modulation is an intriguing part of scientific research. It well established that the immune plays a crucial role in orchestrating cellular and molecular key mediators, thus establishing powerful defense barrier against infectious pathogens. Gut microbiota represent complex community approximately hundred trillion microorganisms live mammalian gastrointestinal (GI) tract, contributing to maintenance gut homeostasis via regulation innate adaptive responses. However, impairment crosstalk between intestinal immunity may reflect on detrimental health issues. In this context, many studies have indicated probiotics their bioactive compounds, such as bacteriocins short chain fatty acids (SCFAs), display distinct immunomodulatory properties through which they suppress inflammation enhance restoration microbial diversity pathological states. This review highlights fundamental features probiotics, bacteriocins, SCFAs, make them ideal therapeutic agents for amelioration inflammatory autoimmune diseases. also describes underlying mechanisms emphasizes how influence function cells involved regulating homeostasis. Finally, it discusses future perspectives challenges administration individuals.

Язык: Английский

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Gut/rumen-mammary gland axis in mastitis: Gut/rumen microbiota–mediated “gastroenterogenic mastitis”

Journal of Advanced Research, Год журнала: 2023, Номер 55, С. 159 - 171

Опубликована: Фев. 22, 2023

Mastitis is an inflammatory response in the mammary gland that results huge economic losses breeding industry. The aetiology of mastitis complex, and pathogenesis has not been fully elucidated. It commonly believed induced by pathogen infection induces a local response. However, clinic, often comorbid or secondary to gastric disease, control effects targeting are limited. In addition, recent studies have found gut/rumen microbiota contributes development proposed gut/rumen–mammary axis. Combined with indicating disturbance can damage gut mucosa barrier, bacteria their metabolites migrate distal extraintestinal organs. occurrence related only external pathogenic microorganisms but also gastroenterogennic pathway. We propose pathological concept "gastroenterogennic mastitis" believe axis–mediated pathway mechanism mastitis". To clarify summarizing reports on effect provide research basis direction for further understanding solving difficulties encountered prevention mastitis.

Язык: Английский

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The interaction between gut microbiome and bone health

Current Opinion in Endocrinology Diabetes and Obesity, Год журнала: 2024, Номер 31(3), С. 122 - 130

Опубликована: Апрель 8, 2024

This review critically examines interconnected health domains like gut microbiome, bone health, interleukins, chronic periodontitis, and coronavirus disease 2019 (COVID-19), offering insights into fundamental mechanisms clinical implications, contributing significantly to healthcare biomedical research.

Язык: Английский

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Boosting vaccine effectiveness: The groundbreaking role of probiotics

Journal of Agriculture and Food Research, Год журнала: 2024, Номер 16, С. 101189 - 101189

Опубликована: Май 6, 2024

Probiotics, the health-promoting members of gut microbiota, have been shown to enhance mucosal and systemic immunity, stimulate cytokines, chemokines, antibodies, regulate T-cell activity. On other hand, traditional adjuvants like alum limitations, researchers are exploring probiotics as a new generation vaccine treat immune disorders effectiveness. For instance, studies show that probiotic strains Lactobacillus rhamnosus GG (LGG) can improve response vaccines against rotavirus, SARS-CoV-2, influenza. Besides, delivered through various routes (oral ocular) could offer broader protection wider range infections. not only boost system but also trigger production anti-inflammatory cytokines regulatory cells, they potential in cancer immunotherapy. Studies demonstrate LGG Bifidobacterium longum increase efficacy by promoting T cell infiltration, thereby inhibiting tumor growth. Additionally, suggest specific L. SL42 casei might be beneficial for cow's milk allergies. In line with this, research on use peanut allergies shows promise. However, there is need more understand mechanisms, identify optimal strains, determine timing duration administration clinical outcomes. This review aimed shed light impact immunomodulatory immunogenic agents immunizations, well their infectious diseases, allergies, suppression.

Язык: Английский

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Fermented foods: a perspective on their role in delivering biotics

Frontiers in Microbiology, Год журнала: 2023, Номер 14

Опубликована: Май 12, 2023

Fermented foods are often erroneously equated with probiotics. Although they might act as delivery vehicles for probiotics, or other ‘biotic’ substances, including prebiotics, synbiotics, and postbiotics, stringent criteria must be met a fermented food to considered ‘biotic’. Those include documented health benefit, sufficient product characterization (for probiotics the strain level) testing. Similar functional ingredients, benefits go beyond that of product’s nutritional components matrix. Therefore, ‘fermented food’ ‘probiotic’ terms may not used interchangeably. This concept would apply biotics well. In this context, capacity deliver one, several, all defined so far will depend on microbiological chemical level characterization, reproducibility technological process produce foods, evidence conferred by biotics, well type amount testing carried out show probiotic, prebiotic, synbiotic, postbiotic food.

Язык: Английский

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Mechanisms of medicinal, pharmaceutical, and immunomodulatory action of probiotics bacteria and their secondary metabolites against disease management: an overview

Folia Microbiologica, Год журнала: 2024, Номер 69(3), С. 549 - 565

Опубликована: Март 27, 2024

Язык: Английский

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Connection between Celiac Disease and Systemic Lupus Erythematosus in Children—A Development Model of Autoimmune Diseases Starting from What We Inherit to What We Eat

Nutrients, Год журнала: 2023, Номер 15(11), С. 2535 - 2535

Опубликована: Май 29, 2023

Celiac disease (CD) and systemic lupus erythematosus (SLE) are two diseases intensively studied in all age groups, with an increasing incidence at the global level, possibly due to increased awareness of their accurate diagnosis as a consequence new research innovation technologies that have appeared medicine. The first is controllable condition found approximately 1% entire population form reaction environmental stimuli affecting individuals genetic susceptibility, causing gluten intolerance, gastrointestinal extradigestive symptoms, starting from subclinical stages culminating severe malabsorption. On other hand, autoimmune chameleon-like symptoms mainly female sex, which leaves its clinical mark on most organs, skin, eyes, kidneys cardiovascular, pulmonary, neurological, osteoarticular, hematological systems. Current studies focus correlation between celiac pathologies such thyroiditis (Hashimoto Graves–Basedow), type I diabetes, erythematosus. current review aims present summary data specialized literature regarding intercurrents by analyzing recent published PubMed.

Язык: Английский

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An overview of prebiotics and their applications in the food industry

European Food Research and Technology, Год журнала: 2023, Номер 249(11), С. 2957 - 2976

Опубликована: Авг. 5, 2023

Язык: Английский

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Microstructural analysis of meat and internal organs of broiler chickens using a probiotic biological product

Ukrainian journal of veterinary sciences, Год журнала: 2024, Номер 15(1), С. 24 - 47

Опубликована: Янв. 19, 2024

Probiotic preparation containing bacteria of the genus Bacillus subtilis and licheniformis used for feeding broiler chickens to improve feed digestion, nutrient absorption, increase immune status productivity, prevention treatment various poultry diseases. The purpose study is conduct histological tests chicken slaughter products when they were administered a probiotic biologic medical product in doses of: 0.5 g, 2.0, 4.0 g per 10 dm3 water. material was examined by method. It found that muscle fibres pectoralis major are same type, evenly directed, cytoplasm moderately eosinophilic, uniformly light pink, minor layers adipose tissue between bundles fibres. morphological architectonics heart preserved, cardiomyocytes homogeneous have clear orientation. microstructure liver unchanged: hepatocytes collected type groups; central veins desolate; these cells homogeneous, clear, pink; nuclei weakly basophilic. In spleen, follicular structure formed, leukocytes diffusely placed at different stages differentiation; vessels significant numbers, thickened, calibre. cuticle muscular part stomach contains epithelial layer, volume connective base layer revealed; located under mesenchymal cuticle. Lungs bronchial tubes throughout structure, which contain blood cells. According results conducted studies, beneficial effect biological dose g/10 water on morphology internal organs established. Therefore, during drinking can be recommended productivity produce safe products. practical significance obtained determine features with probiotics its products, important obtaining best from use

Язык: Английский

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