Plant Biotechnology Journal,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 6, 2024
Summary
Pigments,
as
coloured
secondary
metabolites,
endow
the
world
with
a
rich
palette
of
colours.
They
primarily
originate
from
plants
and
microorganisms
play
crucial
roles
in
their
survival
adaptation
processes.
In
this
article,
we
categorize
pigments
based
on
chemical
structure
into
flavonoids,
carotenoids,
pyrroles,
quinones,
azaphilones,
melanins,
betalains,
flavins,
others.
We
further
meticulously
describe
colours,
sources,
biosynthetic
pathways,
including
key
enzymatic
steps
regulatory
networks
that
control
pigment
production,
both
microorganisms.
particular,
highlight
role
transport
proteins
transcription
factors
fine‐tuning
these
pathways.
Finally,
introduce
use
practical
production
research,
aiming
to
provide
new
insights
directions
for
application
compounds
diverse
fields,
such
agriculture,
industry,
medicine.
Saudi Journal of Biological Sciences,
Год журнала:
2023,
Номер
31(1), С. 103878 - 103878
Опубликована: Ноя. 25, 2023
Tamarindus
indica
L.,
is
widely
used
tree
in
ayurvedic
medicine.
Here,
we
aimed
to
understand
the
presence
of
important
constituents
seeds
and
peel
Tamarind
fruits
their
biological
activities.
Hence,
are
for
further
extraction
process
by
soxhlet
method
(chloroform
ethyl
acetate
solvents).
Results
suggest
that
extract
(seeds)
consists
terpenoids
(72.29
±
0.513
mg/g),
phenolic
content
(68.67
2.11
mg/g)
flavonoids
(26.36
2.03
whereas
chloroform
has
(42.29
0.98
mg/g).
Similarly,
(peel)
(25.96
3.20
(46.36
(62.93
0.987
Furthermore,
anti-inflammation
activity
results
revealed
was
found
be
more
effective
with
IC50
226.14
µg/ml
protein
denaturation
analysis
245.5
on
lipoxygenase
inhibition
activity.
Chloroform
(peel
seeds)
shown
better
antioxidant
using
DPPH
than
seeds).
Ethyl
showed
impressive
potency
inhibiting
growth
fungus,
Candida
albicans.
Additionally,
Escherichia
coli
Bacillus
cereus.
GC-MS
existence
diverse
set
phytochemicals
each
extract.
Overall,
comparative
studies
highlight
effectiveness
extracts
extracts.
Moreover,
acetate)
contains
a
wide
range
compounds
(including
flavonoids,
isovanillic
acid,
fatty
acids
compounds)
which
can
utilized
therapeutic
purpose.
Life,
Год журнала:
2023,
Номер
13(12), С. 2270 - 2270
Опубликована: Ноя. 28, 2023
Mango
and
its
by-products
have
traditional
medicinal
uses.
They
contain
diverse
bioactive
compounds
offering
numerous
health
benefits,
including
cardioprotective
metabolic
properties.
This
study
aimed
to
explore
the
impact
of
mango
fruit
on
human
health,
emphasizing
syndrome
components.
PUBMED,
EMBASE,
COCHRANE,
GOOGLE
SCHOLAR
were
searched
following
PRISMA
guidelines,
COCHRANE
handbook
was
utilized
assess
bias
risks.
In
vivo
in
vitro
studies
shown
several
benefits
by-products.
For
this
systematic
review,
13
met
inclusion
criteria.
The
collective
findings
indicated
that
utilization
various
forms—ranging
from
fresh
slices
puree
by-products,
leaf
extract,
powder,
mangiferin—yielded
many
favorable
effects.
These
encompassed
enhancements
glycemic
control
improvements
plasma
lipid
profiles.
Additionally,
reduces
food
intake,
elevates
mood
scores,
augments
physical
performance
during
exercise,
improves
endothelial
function,
decreases
incidence
respiratory
tract
infections.
Utilizing
supports
demand
for
healthier
products.
approach
also
aids
environmental
conservation.
Furthermore,
development
mango-derived
nanomedicines
aligns
with
sustainable
goals
offers
innovative
solutions
healthcare
challenges
whilst
being
environmentally
conscious.
Frontiers in Cellular and Infection Microbiology,
Год журнала:
2024,
Номер
14
Опубликована: Фев. 29, 2024
Flavonoids,
a
diverse
group
of
polyphenolic
compounds
found
in
various
plant-based
foods,
have
garnered
attention
for
their
potential
combating
Hepatitis
B
Virus
(HBV)
infection.
Flavonoids
demonstrated
promising
anti-HBV
activities
by
interfering
with
multiple
stages
the
HBV
life
cycle,
making
them
candidates
novel
antiviral
agents.
Certain
plant
families,
such
as
Theaceae
,
Asteraceae
Lamiaceae
and
Gentianaceae
are
particular
interest
flavonoid-rich
members
activities.
Evidences,
both
vitro
vivo
supports
flavonoids.
These
subsets
compound
exert
effects
through
mechanisms,
including
inhibiting
viral
entry,
disrupting
replication,
modulating
transcription
factors,
enhancing
immune
response,
inducing
autophagy.
The
antioxidant
properties
flavonoids
play
crucial
role
oxidative
stress
associated
Several
like
epigallocatechin
gallate
(EGCG),
proanthocyanidin
(PAC),
hexamethoxyflavone,
wogonin,
baicalin
shown
significant
potential,
holding
promise
therapeutic
Synergistic
between
existing
therapies
offer
approach
to
enhance
efficacy
reduce
drug
resistance.
Challenges,
limited
bioavailability,
translation
from
preclinical
studies
clinical
practice,
understanding
precise
targets,
need
be
addressed.
Future
research
should
focus
on
trials,
combination
therapies,
development
flavonoid
derivatives
improved
optimizing
effectiveness
managing
chronic
infections.
Molecules,
Год журнала:
2024,
Номер
29(3), С. 691 - 691
Опубликована: Фев. 2, 2024
The
blueberry,
a
deciduous
shrub
in
the
Ericaceae
family,
is
celebrated
for
its
delightful
flavor,
sweetness,
and
abundance
of
anthocyanins
antioxidants,
qualities
that
have
garnered
significant
attention
their
potential
health
benefits.
Blueberries
grown
diverse
environments
exhibit
varied
anthocyanin
profiles,
often
influenced
by
factors
such
as
altitude
climate.
Varietal
groups
worldwide
been
bred
categorized
based
on
growth
habits
specific
cold
requirements,
particularly
with
southern
highbush
cultivars
thriving
temperate
climates,
demonstrating
tolerance
to
higher
altitudes
or
cooler
climates-a
result
hybridizations
involving
various
Applied Food Research,
Год журнала:
2024,
Номер
4(1), С. 100399 - 100399
Опубликована: Фев. 13, 2024
The
anthocyanins
(ACN)
are
water-soluble
pigments
present
in
the
pericarp
or
aleurone
layer
of
maize
kernel.
authentic
color
landraces
being
grown
by
farmers
at
a
smaller
scale
restricted
to
local
consumers.
These
ears
(cob
with
kernels)
which
receiving
more
prominence
not
only
for
their
environment
friendly
and
natural
colorant
properties
but
also
numerous
health
benefits
from
edible
food
pigments.
Since
anthocyanin
have
significant
effects
on
animal
health,
it
is
catching
attention
processing
companies
as
well
high-end
culinary
markets.
In
this
review,
we
represented
functional
maize.
Earlier,
studies
best
vitro
tests
were
extrapolatory
now
using
cell
models
trials
providing
foolproof
evidence
significance
corn
anthocyanins.
mechanisms
action
cellular
molecular
level
been
understood.
Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology,
Год журнала:
2024,
Номер
16(3)
Опубликована: Май 1, 2024
Abstract
Natural
bioactive
compounds
from
plants
exhibit
substantial
pharmacological
potency
and
therapeutic
value.
However,
the
development
of
most
plant
is
hindered
by
low
solubility
instability.
Conventional
pharmaceutical
forms,
such
as
tablets
capsules,
only
partially
overcome
these
limitations,
restricting
their
efficacy.
With
recent
nanotechnology,
nanocarriers
can
enhance
bioavailability,
stability,
precise
intracellular
transport
compounds.
Researchers
are
increasingly
integrating
nanocarrier‐based
drug
delivery
systems
(NDDS)
into
natural
with
significant
success.
Moreover,
products
benefit
nanotechnological
enhancement
contribute
to
innovation
optimization
via
self‐assembly,
grafting
modifications,
biomimetic
designs.
This
review
aims
elucidate
collaborative
reciprocal
advancement
achieved
botanical
products,
compounds,
polysaccharides,
proteins,
extracellular
vesicles.
underscores
salient
challenges
in
nanomedicine,
encompassing
long‐term
safety
evaluations
nanomedicine
formulations,
targeting
mechanisms,
biodistribution
complexities,
hurdles
clinical
translation.
Further,
this
study
provides
new
perspectives
leverage
nanotechnology
promoting
for
nanomedical
applications
guiding
progression
NDDS
toward
enhanced
efficiency,
precision,
safety.
article
categorized
under:
Therapeutic
Approaches
Drug
Discovery
>
Emerging
Technologies
Nanotechnology
Biology
Nanoscale
Systems
Foods,
Год журнала:
2023,
Номер
12(21), С. 3969 - 3969
Опубликована: Окт. 30, 2023
Anthocyanins
are
natural
flavonoid
polyphenolic
compounds
widely
found
in
fruits
and
vegetables.
They
exhibit
antioxidant
properties
prophylactic
effects
the
immune
cardiovascular
systems,
confer
protection
against
cancer,
contribute
to
prevention
of
diseases.
Thus,
their
incorporation
into
functional
foods,
pharmaceuticals,
supplements,
cosmetic
formulations
aims
at
promoting
human
well-being.
This
review
comprehensively
outlined
structural
attributes
anthocyanins,
expanding
upon
diverse
methodologies
employed
for
extraction
production.
Additionally,
stability,
metabolic
pathways,
manifold
physiological
functions
anthocyanins
were
discussed.
However,
constrained
fat
solubility,
susceptibility
instability,
restricted
bioavailability
collectively
curtail
applicability
therapeutic
efficacy.
Consequently,
a
multidimensional
approach
was
imperative,
necessitating
exploration
innovative
pathways
surmount
these
limitations,
thereby
amplifying
utilitarian
significance
furnishing
pivotal
support
continual
advancement
broader
application.
Pathophysiology,
Год журнала:
2024,
Номер
31(3), С. 309 - 330
Опубликована: Июнь 21, 2024
Understanding
how
gut
flora
interacts
with
oxidative
stress
has
been
the
subject
of
significant
research
in
recent
years.
There
is
much
evidence
demonstrating
existence
microbiome–oxidative
interaction.
However,
biochemical
basis
this
interaction
still
unclear.
In
narrative
review,
possible
pathways
microbiota
and
are
presented,
among
which
genetic
underpinnings
play
an
important
role.
Trimethylamine-N-oxide,
mitochondria,
short-chain
fatty
acids,
melatonin
also
appear
to
roles.
Moreover,
relationship
between
microbiome
obesity,
metabolic
syndrome,
chronic
ethanol
consumption,
dietary
supplements,
medications
considered.
An
investigation
correlation
bacterial
community
features
OS
parameter
changes
under
normal
pathological
conditions
might
provide
information
for
determination
new
methods.
Furthermore,
such
could
contribute
establishing
a
foundation
determining
linkers
microbiome–OS
association.
