Artemisinin and Its Derivatives as Potential Anticancer Agents

Molecules, Год журнала: 2024, Номер 29(16), С. 3886 - 3886

Опубликована: Авг. 16, 2024

Artemisinin is a natural sesquiterpene lactone obtained from the traditional Chinese medicinal herb Artemisia annua L. (qinghao). and its derivatives share an unusual endoperoxide bridge are extensively used for malaria treatment worldwide. In addition to antimalarial activities, artemisinin have been reported exhibit promising anticancer effects in recent decades. this review, we focused on research progress of with potential activities. The pharmacological effects, mechanisms, clinical trials cancer therapy were discussed. This review may facilitate future exploration as effective agents.

Язык: Английский

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Advances in nanotechnology for targeting cancer-associated fibroblasts: A review of multi-strategy drug delivery and preclinical insights

APL Bioengineering, Год журнала: 2025, Номер 9(1)

Опубликована: Март 1, 2025

Cancer-associated fibroblasts (CAFs) play a crucial role in the tumor microenvironment by promoting growth, immune evasion, and metastasis. Recently, drug delivery systems targeting CAFs have emerged as promising long-term effective approach to cancer treatment. Advances nanotechnology, particular, led development of nanomedicine designed specifically target CAFs, offering new possibilities for precise personalized therapies. This article reviews recent progress using nanocarriers that CAFs. Additionally, we explore potential combining multiple therapies, such chemotherapy immunotherapy, with enhance efficacy overcome resistance. Although many preclinical studies show promise, clinical application still faces considerable challenges, especially terms penetration large-scale production. Therefore, this review aims provide fresh perspective on CAF-targeted highlight future research directions applications.

Язык: Английский

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Repositioning antimalarial drugs as anticancer agents: focus on Tafenoquine

Experimental Cell Research, Год журнала: 2025, Номер unknown, С. 114551 - 114551

Опубликована: Апрель 1, 2025

Язык: Английский

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Investigation of impact of siderophore and process variables on production of iron enriched Saccharomyces boulardii by Plackett–Burman design

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Окт. 1, 2024

Язык: Английский

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Surface chemical and electronic properties of functionalized Fe3O4 nanoparticles influencing their cytotoxicity

Applied Surface Science, Год журнала: 2024, Номер unknown, С. 161873 - 161873

Опубликована: Ноя. 1, 2024

Язык: Английский

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