High-Altitude Medicinal Plants as Promising Source of Phytochemical Antioxidants to Combat Lifestyle-Associated Oxidative Stress-Induced Disorders

Pharmaceuticals, Год журнала: 2024, Номер 17(8), С. 975 - 975

Опубликована: Июль 23, 2024

Oxidative stress, driven by reactive oxygen, nitrogen, and sulphur species (ROS, RNS, RSS), poses a significant threat to cellular integrity human health. Generated during mitochondrial respiration, inflammation, UV exposure pollution, these damage cells contribute pathologies like cardiovascular issues, neurodegeneration, cancer, metabolic syndromes. Lifestyle factors exert substantial influence on oxidative stress levels, with mitochondria emerging as pivotal players in ROS generation equilibrium. Phytochemicals, abundant plants, such carotenoids, ascorbic acid, tocopherols polyphenols, offer diverse antioxidant mechanisms. They scavenge free radicals, chelate metal ions, modulate signalling pathways mitigate damage. Furthermore, plants thriving high-altitude regions are adapted extreme conditions, synthesize secondary metabolites, flavonoids phenolic compounds bulk quantities, which act form robust defence against including radiation temperature fluctuations. These promising sources for drug development, offering innovative strategies manage stress-related ailments enhance Understanding harnessing the potential of phytochemicals from represent crucial steps combating stress-induced disorders promoting overall wellbeing. This study offers comprehensive summary production physio-pathological aspects lifestyle-induced explores antioxidants. Additionally, it presents an appraisal medicinal antioxidants, highlighting their development creation therapeutic approaches.

Язык: Английский

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Growth, productivity and phytochemicals of Coriander in responses to foliar application of Acacia saligna fruit extract as a biostimulant under field conditions

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Фев. 5, 2024

Abstract The application of natural extracts to vegetable plants can increase production, optimize nutrient and water uptake, mitigate the effects stress on by enhancing primary secondary metabolism. In this study, Acacia saligna (Labill.) H.L.Wendl. fruit aqueous extract (FAE) was applied as a foliar assess demonstrate its growth, productivity, phytochemicals coriander ( Coriandrum sativum L.) plants. A. FAE (2%, 4%, 6%), each combined with 50% recommended dose N fertilizer over course two successive seasons in field. These treatments were compared control treatment, which used 100% N. four tested set up randomized complete block design three replicates for total 12 experimental plots. Each replicate (experimental plot) 3 m 2 (2 × 1.5 ) size included 300 seeds/m . examined using chromatographic spectrophotometric methods, where essential oils (EOs) extracted from leaves analyzed Gas chromatography–mass spectrometry (GC–MS), while phenolic flavonoid compounds High Performance Liquid Chromatography (HPLC). With (4%) + fertilizer, levels solid content, carbohydrates, protein, phenols, antioxidant activity, well chlorophyll a, b, carotenoids, increased at harvest. treatment 6% did not observe significant improvement growth parameters because anticipated allelopathic effects. By GC–MS analysis, major EO 2-octyn-1-ol (23.93%), 2-butyl-1-octanol (8.80%), treated 2% E )-2-decen-1-ol (32.00%), 1-methoxymethoxy-oct-2-yne (13.71%), 4% -2-undecen-1-ol (32.70%), 3,5,5-trimethyl-1-hexene (8.91%), (6%) phytol (80.44%), Z )6,( )9-pentadecadien-1-ol (13.75%). components 7-hydroxyflavone, naringin, rutin, quercetin, kaempferol, luteolin, apigenin, catechin presented variable concentrations according utilized identified HPLC analysis methanol combination (2, 4, 6%) fertilization (50% dose) (100% dose). biostimulant seems improve plant simultaneously lowering consumption. Future research will be needed further study effectiveness several various conditions and/or species.

Язык: Английский

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Duckweed (Lemna minor) biomass aqueous extract-mediated synthesis of silver nanoparticles as a novel formulation era for long-term efficacy against Tribolium castaneum and Sitophilus oryzae adults on wheat seeds

Biomass Conversion and Biorefinery, Год журнала: 2024, Номер unknown

Опубликована: Фев. 14, 2024

Abstract Plant-based biological nanoparticles (NPs) synthesis is a new technique where molecules and their combinations in plant aqueous extract decrease metal salts, which have dual role the fabrication stabilization of metallic NPs. Here, we used from duckweed ( Lemna minor ) to biosynthesize silver NPs (AgNPs), were verified by shift color pale brown dark brown. AgNPs then further characterized.By High Performance Liquid Chromatography (HPLC) analysis, most abundant compound vanillic acid, benzoic quercetin, resveratrol, ferulic rutin, p-hydroxy rosmarinic ellagic o-coumaric acid. Scanning Electron Microscopy (SEM), micrograph revealed spherical-shaped synthesized with an average size 40.56 nm. Capping stabilizing agents, present form various biomolecules, responsible for prolonged stability produced AgNPs, as proven FTIR analysis. The Zeta potential surface electric charges was determined be − 27 mV. UV–Vis spectrum indicates broad plasmon resonance (SPR) absorption peak at 450 EDAX test confirmed presence suspension. Green-produced had highest insecticidal activity against Sitophilus oryzae , LC 50 values 6.08 µg/mL compared adults Tribolium castaneum 7.03 µg/mL. All assays clearly showed that formulated 1% DP increasing exposure intervals concentrations resulted gradual increase mortality adult T . S. exposed treated wheat seeds. effect post-toxic levels on progeny counts T. grains. concentration 0.2 g/100 g seed being effective one, higher reductions F1-progenythan than other malathion (1% DP) during storage 1 year, well significant positive germination storage. work suggests eco-friendly biosynthesized are promising green insecticides can alternative method control protect seeds overcome synthetic insecticide problems.

Язык: Английский

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Copper oxide nanoparticles-mediated Heliotropium bacciferum leaf extract: Antifungal activity and molecular docking assays against strawberry pathogens

Open Chemistry, Год журнала: 2024, Номер 22(1)

Опубликована: Янв. 1, 2024

Abstract In the current study, Heliotropium bacciferum leaf extract was used to biosynthesize copper oxide nanoparticles (CuO-NPs). Various analytical techniques were characterize produced CuO-NPs. Transmission electron microscope investigation indicated well-distributed spherical particles in various development phases. The particles’ diameters ranged from 22.15 37.01 nm, with an average of 24.8 ± 6.1 nm. Energy dispersive X-ray examination confirmed presence nanoscale Cu ions at a high concentration, as seen by strong signal peak 1 keV. Fourier transform infrared spectrum revealed functional groups on green-produced CuO-NPs, evidenced multiple absorption beaks. bands found 3,195 and 2,916 cm −1 that phenolic flavonoid compounds’ alcohols alkanes stretching C–H. Also, band 1,034 is typically attributed CuO production. CuO-NPs exhibited significant bioactivity against isolated molecularly identified fungal strains, including Rhizoctonia solani (OR116528), Fusarium oxysporum (OR116508), Botrytis cinerea (OR116491). Remarkably, highest inhibition percentages recorded 100 µg/mL, values 81.48, 71.11, 50.74% for R. , F. B. respectively. Molecular docking interactions binding affinity −5.1 oxidoreductase −5.2 −5.4 chitin synthase Consequentially, biosynthesized could be employed antifungal biocontrol agents, well using H. synthesis sustainable agricultural applications.

Язык: Английский

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Seaweed extract and biological fertilizer to stimulate the growth of Khaya senegalensis irrigated with agricultural drainage water in greenhouse conditions for a sustainable forest plantation industry in Northern Egypt

Ecological Engineering, Год журнала: 2025, Номер 212, С. 107531 - 107531

Опубликована: Янв. 21, 2025

Язык: Английский

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HPLC and GC-MS analyses of phytochemicals from Ficus carica leaf extract and essential oil along with their antimicrobial properties

Journal of Agriculture and Food Research, Год журнала: 2025, Номер unknown, С. 101687 - 101687

Опубликована: Фев. 1, 2025

Язык: Английский

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Comparative Analysis of Horticultural and Animal Waste Compost: Physicochemical Properties and Impact on Plant Growth

Agronomy, Год журнала: 2025, Номер 15(3), С. 516 - 516

Опубликована: Фев. 20, 2025

In Europe, food and agricultural waste amount to millions of tonnes annually. Effective management valorisation these residues result in environmental benefits foster opportunities within the circular economy. Composting has emerged as a sustainable method convert into fertiliser, enhancing soil fertility, water retention, crop resilience against diseases. However, an adequate compost production process is vital obtain functional fertiliser. this study, controlled conditions self-produced from horticultural (C1) was compared two other commercial composts, one similar vegetable origin (C2) another chicken manure (C3). Physicochemical parameters nutrient contents three types were analysed, phytotoxicity plant development tests carried out on Lolium multiflorum Lam. seeds Pistacia lentiscus L. seedlings. C1 presented fertility germination C3 showed best seedling development. contrast, C2 low levels germination, because impurities possible substances inhibiting growth, suggesting inadequate formation processes. Finally, C3, although it data C1, produced worst results seedlings, probably high salinity values phosphorus content.

Язык: Английский

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Assessment of detoxification enzyme activities and hemocyte examination of Spodoptera littoralis (Boisduval) (Lepidoptera: Noctuidae) in response to Mentha pulegium and Artemisia camphorata extracts

Phytoparasitica, Год журнала: 2025, Номер 53(3)

Опубликована: Апрель 15, 2025

Язык: Английский

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Chemical compositions and antifungal activity of Corymbia citriodora, Cupressus macrocarpa, and Syzygium cumini extracts: GC–MS and HPLC analysis of essential oils and phenolic compounds

Biomass Conversion and Biorefinery, Год журнала: 2023, Номер unknown

Опубликована: Ноя. 27, 2023

Abstract This study was undertaken to explore the content and chemical constituents of essential oils (EOs) methanol leaf extracts (MLEs) from Corymbia citriodora , Cupressus macrocarpa Syzygium cumini . Chromatographic analyses GC–MS HPLC were used. The EOs MLEs prepared at concentrations 0, 6, 12, 25, 50 mg/L, while extract 500, 1000, 2000, 4000 mg/L. Sapwood blocks Pinus sylvestris in dimension 0.5 × 2 cm autoclaved 121 °C, each wood block received 100 µL MEs. bioactivities wood-treated or MEs measured against growth Fusarium solani MW947256. By GC–MS, main compounds C. citronellal, citronellol, p-cymene, spathulenol, isopulegol with values 23.95, 9.80, 9.32, 9.29, 5.38%, respectively, Cup. leaves sabinene (11.94%), 4-terpinenol (11.34%), citronellol (9.59%), citronellal (9.85%), p-cymene (7.67%), spathulenol (5.24%), γ -terpinene (5.05%), camphor (4.31%), limonene (3.2%), S. trans-β-ocimene (19.11%), α-pinene (18.79%), caryophyllene (9.30%), (Z)-β-ocimene (8.16%), (6%). HPLC, most abundant phenolic benzoic acid (8.11 μg/g), gallic (7.96 syringic (7.59 catechol (6.85 (6.78 cinnamic (10.66 caffeic (9.87 ellagic (8.76 μg/g). highest percentages inhibition (65.71% 35.71%) F. seen treated 25 respectively. maximum level (92.85%) when a dose mg/L applied samples, followed by (70.00%) compared positive control azoxystrobin + difenoconazole (1000 mg/L), which caused 100% findings indicated that bioactive chemicals present these trees have strong antifungal properties.

Язык: Английский

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The toxicity, repellent, and biochemical effects of four wild plant extracts against Aphis gossypii Glover and Phenacoccus solenopsis Tinsley: HPLC analysis of phenolic compounds

Phytoparasitica, Год журнала: 2024, Номер 52(5)

Опубликована: Ноя. 1, 2024

Abstract The insecticidal and repellent activities of the four wild plant extracts: stinging nettle, Urtica dioica L., white henbane, Hyoscyamus albus camphorweeds, Pluchea dioscoridis cocklebur, Xanthium strumarium L. were tested compared to insecticide spirotetramat against 3 rd nymphal instar Aphis gossypii Glover adult females Phenacoccus solenopsis Tinsley after 24 48 h treatment. Their effects on acetylcholinesterase (AChE) glutathione-S-transferase (GST) enzyme also assessed explore their possible mechanisms action. phenolic compounds extracts investigated by high-performance liquid chromatography (HPLC) analysis. most abundant in methanol extract from P. gallic acid (14.45 µg/mL), cinnamic (11.44 µg/mL); U. caffeic (15.32 µg/mL) syringic (13.47 H. (7.12 catechol (5.33 X. p -coumaric (24.53 pyrogallol (18.35 µg/mL). According LC 50 values, contact toxicity , A. was 40.3, 60.6, 56.2, 32.3 mg/L, whereas, 56.4, 67.5, 64.3, 36.2 (17.2 24.5 mg/L), respectively, at highest repellency rates observed with values for (63.2 60.3%), followed (46.2 43.5%), (45.3 42.8%), (38.8 35.2%) (78.5 76.2%) h, but decreased time. AChE GST pests significantly inhibited, control spirotetramat, dose time-dependent effects. These findings indicate that may be suggested as viable alternatives aphids mealybugs control.

Язык: Английский

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