Two-dimensional
(2D)
nanostructured
materials
have
taken
a
special
interest
among
researchers
due
to
their
layered
structural
feature
with
high
aspect
ratio
showing
versatile
properties.
nanomaterials
like
graphene,
graphene
oxide
(GO),
reduced
(rGO),
nanoclay,
double
hydroxide
(LDH),
metal
organic
framework
(MOF),
graphitic
carbon
nitride
(g-C
3
N
4
),
hexagonal
boron
(h-BN),
MXene,
transition
dichalcogenide
(TMD),
black
phosphorus
(BP),
(TMO),
and
covalent
(COF)
are
potential
reinforcements
in
polymer
nanocomposites
(PNCs)
by
which
different
properties
thermal
properties,
mechanical
strength,
gas
barrier
flame
retarding
nature,
antibacterial
behavior
of
PNCs
enhanced,
enabling
application
the
biomedical
field.
When
2D
reinforced
polymers
such
as
chitosan,
poly(lactic
acid)
(PLA),
poly(acrylic
acid)(PAA),
poly(vinyl
alcohol)
(PVA),
poly(glycolic
(PGA),
poly(methyl
methacrylate)
(PMMA),
albumin,
then
prepared
become
more
useful
for
applications
compared
other
reinforcing
nanomaterials.
The
present
chapter
focuses
on
state-of-the-art
nanomaterials-based
drug
delivery,
tissue
engineering,
gene
therapy,
wound
healing,
biosensing.
From
critical
analysis,
it
is
found
that
sandwiched
laminar
structure
unique
factor
change
towards
applications.
Depending
interfacial
interaction
surface
polymer,
graphene-based
affinity
Different
analytically
discussed
inclusion
schemes
table
better
understanding
readers.
Carbon,
Год журнала:
2024,
Номер
223, С. 118970 - 118970
Опубликована: Фев. 26, 2024
Hydrogel-integrated
graphene
superstructures
(GSSs)
represent
a
promising
platform
for
applications
in
tissue
engineering
and
regenerative
medicine.
Graphene,
two-dimensional
carbon-based
material,
possesses
remarkable
mechanical,
thermal,
electrical
characteristics,
making
it
strong
candidate
application
biomedicine.
Researchers
have
pursued
the
integration
of
with
hydrogels,
known
their
biocompatibility
ability
to
provide
conducive
environment
cellular
growth,
craft
sophisticated
scaffolds
tailored
needs.
The
hydrogels
enables
construction
3D
frameworks
that
closely
mimic
natural
extracellular
matrix
(ECM)
found
biological
tissues.
Hydrogels
furnish
biocompatible,
well-hydrated
environment,
while
component
bolsters
scaffold's
mechanical
integrity
conductivity.
This
amalgamation
enhances
adhesion,
differentiation,
proliferation,
thereby
facilitating
regeneration.
A
notable
advantage
hydrogel-integrated
GSSs
lies
capacity
support
growth
differentiation
variety
cell
types
such
as
PC12,
MG-63,
U-87,
MC3T3-E1
lines.
Overall,
exhibit
great
potential
advancing
biomimetic
combination
unique
properties
development
advanced
scaffold
systems
Further
research
this
domain
will
play
crucial
role
medicine
treatment
various
diseases
injuries.
Current Issues in Molecular Biology,
Год журнала:
2024,
Номер
46(1), С. 585 - 611
Опубликована: Янв. 5, 2024
Numerous
surgeries
are
carried
out
to
replace
tissues
that
have
been
harmed
by
an
illness
or
accident.
Due
various
surgical
interventions
and
the
requirement
of
bone
substitutes,
emerging
field
tissue
engineering
attempts
repair
damaged
with
help
scaffolds.
These
scaffolds
act
as
template
for
regeneration
controlling
development
new
cells.
For
creation
functional
organs,
there
three
elements
play
very
crucial
role:
cells,
signals
achievement
these
aims,
types
natural
polymers,
like
chitosan,
chitin,
cellulose,
albumin
silk
fibroin,
used
preparation
Scaffolds
produced
from
polymers
many
advantages:
they
less
immunogenic
well
being
biodegradable,
biocompatible,
non-toxic
cost
effective.
The
hierarchal
structure
bone,
microscale
nanoscale,
is
mostly
made
up
organic
inorganic
components
nanohydroxyapatite
collagen
components.
This
review
paper
summarizes
knowledge
updates
information
about
use
scaffolds,
their
application
in
recent
research
trends
area
(BTE).
article
extensively
explores
related
analyze
advancement
nanotechnology
treatment
bone-related
diseases
repair.
Micromachines,
Год журнала:
2022,
Номер
13(7), С. 1123 - 1123
Опубликована: Июль 16, 2022
Graphene-based
nanomaterials
have
gained
a
lot
of
interest
over
the
last
years
in
flexible
electronics
due
to
their
exceptional
electrical,
mechanical,
and
optoelectronic
properties,
as
well
potential
surface
modification.
Their
flexibility
processability
make
them
suitable
for
electronic
devices
that
require
bending,
folding,
stretching,
which
cannot
be
fulfilled
by
conventional
electronics.
These
can
assembled
with
various
types
organic
materials,
including
polymers,
biomolecules,
generate
variety
nanocomposites
greater
stretchability
healability,
higher
stiffness,
electrical
conductivity,
thermal
stability
lighting
display
technologies.
This
article
summarizes
main
characteristics
synthesis
methods
graphene,
its
oxidized
form
graphene
oxide
(GO),
reduced
GO
derivative,
corresponding
polymeric
composites,
provides
brief
overview
about
some
recent
examples
these
applications,
electrodes
solar
cells
supercapacitors,
textiles,
transistors.
Journal of Nanobiotechnology,
Год журнала:
2023,
Номер
21(1)
Опубликована: Сен. 4, 2023
Abstract
Impaired
wound
healing
is
a
significant
complication
of
diabetes.
Platelet-derived
extracellular
vesicles
(pEVs),
rich
in
growth
factors
and
cytokines,
show
promise
as
powerful
biotherapy
to
modulate
cellular
proliferation,
angiogenesis,
immunomodulation,
inflammation.
For
practical
home-based
therapy,
however,
pEVs
should
be
incorporated
into
bandages
with
careful
attention
delivery
strategies.
In
this
work,
gelatin-alginate
hydrogel
(GelAlg)
loaded
reduced
graphene
oxide
(rGO)
was
fabricated,
its
potential
diabetic
dressing
investigated.
The
GelAlg@rGO-pEV
gel
exhibited
excellent
mechanical
stability
biocompatibility
vitro,
promising
macrophage
polarization
reactive
oxygen
species
(ROS)-scavenging
capability.
vitro
cell
migration
experiments
were
complemented
by
vivo
investigations
using
streptozotocin-induced
rat
model.
When
exposed
near-infrared
light
at
2
W
cm
−
,
the
effectively
decreased
expression
inflammatory
biomarkers,
regulated
immune
response,
promoted
enhanced
healing.
Interestingly,
also
increased
heat
shock
proteins
involved
protective
pathways.
These
findings
suggest
that
engineered
has
serve
can
responses,
inflammation,
follicle
regeneration
wounds,
potentially
leading
accelerated
chronic
wounds.
Carbohydrate Polymer Technologies and Applications,
Год журнала:
2022,
Номер
5, С. 100266 - 100266
Опубликована: Дек. 9, 2022
The
need
for
solutions
in
the
pharmaceutical
field
that
respond
to
new
needs
regarding
minimum
impact
of
active
substances
on
body
has
led
an
explosion
research
smart
systems
controlled
drug
delivery.
Supramolecular
chemistry
provided
recent
years
powerful
tools
synthesis
these
forms
release,
cyclodextrins
offering
possibility
complex
supramolecular
architectures
meet
requirements.
But
can
be
used
only
with
a
carrier
order
benefit
by
their
excellent
properties
and
this
review
presents
latest
achievements
nanoparticles-based
architectures,
taken
into
account
main
methods
stimuli
control
release
(light-responsive,
pH-responsive,
redox-responsive,
multi-responsive).
also
applications
cooperative
co-delivery
systems,
non-viral
vectors
gene
delivery
theranostics
present
status
commercial
based
characteristics.
Water
scarcity
is
a
global
problem
affecting
millions
of
people.
It
can
lead
to
severe
economic,
social,
and
environmental
consequences.
also
have
several
impacts
on
agriculture,
industry,
households,
leading
decrease
in
human
quality
life.
To
address
water
scarcity,
governments,
communities,
individuals
must
work
synergy
for
the
sake
resources
conservation
implementation
sustainable
management
practices.
Following
this
urge,
enhancement
treatment
processes
development
novel
ones
must.
Here,
we
investigated
potential
applicability
"Green
Aerogels"
treatment's
ion
removal
section.
Three
families
aerogels
originating
from
nanocellulose
(NC),
chitosan
(CS),
graphene
(G)
are
investigated.
In
order
reveal
difference
between
aerogel
samples
in-hand,
"Principal
Component
Analysis"
(PCA)
has
been
performed
physical/chemical
properties
aerogels,
one
side,
adsorption
features,
another
side.
Several
approaches
data
pre-treatments
considered
overcome
any
bias
statistical
method.
different
followed
approaches,
were
located
center
biplot
surrounded
by
properties.
This
would
probably
indicate
similar
efficiency
whether
they
nanocellulose-based,
chitosan-based,
or
even
graphene-based.
brief,
PCA
shown
all
towards
removal.
The
advantage
method
its
capacity
engage
seek
similarities/dissimilarities
multiple
factors,
with
elimination
shortcomings
tedious
time-consuming
bidimensional
visualization.
Journal of Functional Biomaterials,
Год журнала:
2024,
Номер
15(4), С. 82 - 82
Опубликована: Март 25, 2024
Three-dimensional
(3D)
bioprinting
is
a
fast
prototyping
fabrication
approach
that
allows
the
development
of
new
implants
for
tissue
restoration.
Although
various
materials
have
been
utilized
this
process,
they
lack
mechanical,
electrical,
chemical,
and
biological
properties.
To
overcome
those
limitations,
graphene-based
demonstrate
unique
mechanical
electrical
properties,
morphology,
impermeability,
making
them
excellent
candidates
3D
bioprinting.
This
review
summarizes
latest
developments
in
printing
their
application
engineering
regenerative
medicine.
Over
years,
different
approaches
materials,
such
as
graphene,
graphene
oxide
(GO),
reduced
GO
(rGO),
functional
(fGO).
process
involves
controlling
multiple
factors,
dispersion,
viscosity,
post-curing,
which
impact
properties
3D-printed
constructs.
end,
combined
with
demonstrated
prominent
regeneration
potential
bone,
neural,
cardiac,
skin
tissues.
Overall,
may
pave
way
strategies
translational
implications
orthopedics,
neurology,
cardiovascular
areas.
