Exploring wettability difference-driven wetting by utilizing electrospun chimeric Janus microfiber comprising cellulose acetate and polyvinylpyrrolidone DOI Creative Commons
Menglong Wang, Ruiliang Ge, Ping Zhao

и другие.

Materials & Design, Год журнала: 2023, Номер 226, С. 111652 - 111652

Опубликована: Янв. 25, 2023

In exploring the difference in wettability of fibers with various structures, three inner constructions fibers, namely, uniaxial, Janus and chimeric Janus, have been fabricated by electrospinning. electrospun polyvinyl pyrrolidone cellulose acetate were used as a polymer matrix ketoprofen was model drug. Morphologies structures respectively investigated scanning electron microscopy (SEM) Transmission (TEM). Physical states compatibilities materials detected X-ray diffraction (XRD) Fourier transform infrared spectroscopy (FTIR). Water contact angle (WCA) tests conducted to determine between wetting time among assorted fiber membranes. Results showed that gradient could drive water movement wetting, which resulted rapid decrease WCA, prepare membranes compared uniaxial Otherwise, vitro drug release experiments carried out four fitting models applied matching profiles. The results belonged sustained-release systems such influenced diffusion backbone corrosion effects. this study, whether multilayer affect investigated.

Язык: Английский

Recent Combinations of Electrospinning with Photocatalytic Technology for Treating Polluted Water DOI Open Access
He Lv, Yanan Liu,

Yubin Bai

и другие.

Catalysts, Год журнала: 2023, Номер 13(4), С. 758 - 758

Опубликована: Апрель 15, 2023

Dyes, antibiotics, heavy metal ions, and bacteria are important sources of water pollution. How to solve these issues has become a problem in the fields science technology. People have developed variety technologies treat pollutants water. Photocatalytic technology came into being. As simple environmentally friendly treatment technology, it been widely studied by scientific community. Traditional powder photocatalysts cause secondary pollution environment not conducive recycling. Therefore, large specific surface area reusable membrane built electrospinning favorite today’s Nanofiber membranes prepared structures, which can meet needs different occasions. This review summarizes discusses research progress relationship between structure electrospun fiber membranes, their impacts on photocatalytic performance nanofiber membranes. The performance, challenges, future development directions with kinds techniques using photocatalysis pollutants, reviewed.

Язык: Английский

Процитировано

45

Electrospun Biomolecule-Based Drug Delivery Systems DOI Creative Commons
Deng‐Guang Yu, Chang Huang

Biomolecules, Год журнала: 2023, Номер 13(7), С. 1152 - 1152

Опубликована: Июль 20, 2023

Drug delivery, mainly a professional term in pharmaceutics, is field of interdisciplinary intersection and integration [...].

Язык: Английский

Процитировано

44

Integrated Janus nanofibers enabled by a co-shell solvent for enhancing icariin delivery efficiency DOI
Yuhao Sun, Jianfeng Zhou, Zhiyuan Zhang

и другие.

International Journal of Pharmaceutics, Год журнала: 2024, Номер 658, С. 124180 - 124180

Опубликована: Май 4, 2024

Язык: Английский

Процитировано

38

Engineered beads-on-a-string nanocomposites for an improved drug fast-sustained bi-stage release DOI Creative Commons

Wenjian Gong,

Wei Yang, Jianfeng Zhou

и другие.

Nanocomposites, Год журнала: 2024, Номер 10(1), С. 240 - 253

Опубликована: Июнь 12, 2024

Язык: Английский

Процитировано

38

Electrospun medicated gelatin/polycaprolactone Janus fibers for photothermal-chem combined therapy of liver cancer DOI
Jianfeng Zhou, Yaoning Chen, Yang Liu

и другие.

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 269, С. 132113 - 132113

Опубликована: Май 6, 2024

Язык: Английский

Процитировано

37

Electrospun Fenoprofen/Polycaprolactone @ Tranexamic Acid/Hydroxyapatite Nanofibers as Orthopedic Hemostasis Dressings DOI Creative Commons
Chang Huang, Menglong Wang,

Siyou Yu

и другие.

Nanomaterials, Год журнала: 2024, Номер 14(7), С. 646 - 646

Опубликована: Апрель 8, 2024

Dressings with multiple functional performances (such as hemostasis, promoting regeneration, analgesia, and anti-inflammatory effects) are highly desired in orthopedic surgery. Herein, several new kinds of medicated nanofibers loaded active ingredients for providing functions were prepared using the modified coaxial electrospinning processes. With an electrospinnable solution composed polycaprolactone fenoprofen core working fluid, different types unspinnable fluids (including pure solvent, nanosuspension containing tranexamic acid hydroxyapatite, dilute polymeric comprising acid, polyvinylpyrrolidone) explored to implement processes creating multifunctional nanofibers. Their morphologies inner structures assessed through scanning transmission electron microscopes, which all showed a linear format without discerned beads or spindles diameter smaller than 1.0 μm, some them had incomplete core–shell nanostructures, represented by symbol @. Additionally, strange details about sheaths’ topographies observed, included cracks, adhesions, embedded nanoparticles. XRD FTIR verified that drugs presented amorphous state, resulted from fine compatibility among involved components. All samples demonstrated have hydrophilic property exhibited lower water contact angle 40° 300 ms. In vitro dissolution tests indicated was released sustained manner over 6 h typical Fickian diffusion mechanism. Hemostatic intentional distribution on shell sections able endow rapid hemostatic effect within 60 s.

Язык: Английский

Процитировано

33

Hybrid films loaded with 5-fluorouracil and Reglan for synergistic treatment of colon cancer via asynchronous dual-drug delivery DOI Creative Commons
Hai-Rong Mao, Jianfeng Zhou,

Liang Yan

и другие.

Frontiers in Bioengineering and Biotechnology, Год журнала: 2024, Номер 12

Опубликована: Июнь 13, 2024

Combination therapy with oral administration of several active ingredients is a popular clinical treatment for cancer. However, the traditional method has poor convenience, less safety, and low efficiency patients. The combination pharmaceutical techniques advanced material conversion methods can provide new solutions to this issue. In research, kind hybrid film was created via coaxial electrospraying, followed by casting process. films were composed Reglan 5-fluorouracil (5-FU)-loaded cellulose acetate (CA) core-shell particles in polyvinylpyrrolidone (PVP) matrix. Microscopic observations these demonstrated solid cross section loaded particles. X-ray diffraction Fourier-transform infrared tests verified that 5-FU showed amorphous states fine compatibilities polymeric matrices, i.e., PVP CA, respectively. vitro dissolution indicated able desired asynchronous dual-drug delivery, fast release Reglan, sustained 5-FU. controlled mechanisms shown be an erosion mechanism typical Fickian diffusion protocols reported herein pioneer approach fabricating biomaterials multiple drugs, each its own behavior, synergistic cancer treatment.

Язык: Английский

Процитировано

30

Electrosprayed Eudragit RL100 nanoparticles with Janus polyvinylpyrrolidone patches for multiphase release of paracetamol DOI
Jianfeng Zhou, Hao Pan,

Wenjian Gong

и другие.

Nanoscale, Год журнала: 2024, Номер 16(17), С. 8573 - 8582

Опубликована: Янв. 1, 2024

Janus nanoparticles with soluble polyvinylpyrrolidone patches located on the insoluble Eudragit RL100 sides were prepared using a side-by-side electrospraying method and are demonstrated to provide biphasic release of paracetamol in turn faster action longer time periods blood drug concentration for therapy.

Язык: Английский

Процитировано

28

Research Advances in Superabsorbent Polymers DOI Open Access
Yaoyao Yang, Zhiyuan Liang, Rui Zhang

и другие.

Polymers, Год журнала: 2024, Номер 16(4), С. 501 - 501

Опубликована: Фев. 12, 2024

Superabsorbent polymers are new functional polymeric materials that can absorb and retain liquids thousands of times their masses. This paper reviews the synthesis modification methods different superabsorbent polymers, summarizes processing for forms organizes applications research progress in industrial, agricultural, biomedical industries. Synthetic like polyacrylic acid, polyacrylamide, polyacrylonitrile, polyvinyl alcohol exhibit superior water absorption properties compared to natural such as cellulose, chitosan, starch, but they also do not degrade easily. Consequently, it is often necessary modify synthetic or graft groups onto then crosslink them balance material. Compared widely used nanoparticles, on fibers gels rise, particularly notable fields drug delivery, wound dressing, tissue engineering.

Язык: Английский

Процитировано

25

Reverse Gradient Distributions of Drug and Polymer Molecules within Electrospun Core–Shell Nanofibers for Sustained Release DOI Open Access
Y. Chen,

Wenjian Gong,

Zhiyuan Zhang

и другие.

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(17), С. 9524 - 9524

Опубликована: Сен. 1, 2024

Core–shell nanostructures are powerful platforms for the development of novel nanoscale drug delivery systems with sustained release profiles. Coaxial electrospinning is facile and convenient creating medicated core–shell elaborate designs which sustained-release behaviors molecules can be intentionally adjusted. With resveratrol (RES) as a model poorly water-soluble cellulose acetate (CA) PVP polymeric carriers, brand-new electrospun nanostructure was fabricated in this study. The guest RES host CA were designed to have reverse gradient distribution within nanostructures. Scanning electron microscope transmission evaluations verified that these nanofibers had linear morphologies, without beads or spindles, an obvious double-chamber structure. X-ray diffraction patterns Fourier transform infrared spectroscopic results indicated involved components highly compatible presented amorphous molecular state. In vitro dissolution tests new structures able prevent initial burst release, extend continuous-release time period, reduce negative tailing-off effect, thus ensuring better profile than traditional blended drug-loaded nanofibers. mechanism underlying influence structure RES/CA on proposed. Based proof-of-concept demonstration, series advanced functional nanomaterials similarly developed based distributions multi-chamber

Язык: Английский

Процитировано

24