Polymers,
Год журнала:
2025,
Номер
17(2), С. 252 - 252
Опубликована: Янв. 20, 2025
The
applications
of
polymeric
materials
are
being
constantly
reviewed
and
improved.
In
the
present
world,
word
hybrid,
general
idea
combining
two
or
more
inherently
different
approaches,
designs,
is
gaining
significant
attention.
area
sustainable
with
a
low
environmental
impact
also
rapidly
evolving
many
new
discoveries,
including
use
natural
origin
countless
combinations
thereof.
This
review
tries
to
summarize
current
state
knowledge
about
hybrid
their
special
attention
that
can
be
considered
“environmentally
friendly”.
As
application
field
quite
broad,
was
limited
following
topics:
packaging,
medical
applications,
sensors,
water
purification,
electromagnetic
shielding.
Furthermore,
this
points
out
prospects
challenges
for
mentioned
in
terms
creating
novel
solutions
nano
micro-materials
mostly
renewable
origin.
Polymers,
Год журнала:
2024,
Номер
16(17), С. 2536 - 2536
Опубликована: Сен. 7, 2024
In
the
last
few
decades,
there
has
been
a
growing
interest
in
use
of
biodegradable
polymeric
nanoparticles
(BPNPs)
as
carriers
for
various
therapeutic
agents
drug
delivery
systems.
BPNPs
have
potential
to
improve
efficacy
numerous
active
by
facilitating
targeted
desired
site
body.
Biodegradable
polymers
are
especially
promising
nanocarriers
substances
characterized
poor
solubility,
instability,
rapid
metabolism,
and
system
elimination.
Such
molecules
can
be
efficiently
encapsulated
subsequently
released
from
nanoparticles,
which
greatly
improves
their
stability
bioavailability.
Biopolymers
seem
most
suitable
candidates
used
platforms,
due
biocompatibility
biodegradability.
Other
unique
properties
include
low
cost,
flexibility,
stability,
minimal
side
effects,
toxicity,
good
entrapment
potential,
long-term
controlled
release.
An
overview
summarizing
research
results
years
field
successful
fabrication
loaded
with
is
provided.
The
possible
challenges
involving
nanoparticle
under
physiological
conditions
possibility
scaling
up
production
while
maintaining
quality,
well
future
possibilities
employing
BPNPs,
also
reviewed.
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(17), С. 9524 - 9524
Опубликована: Сен. 1, 2024
Core–shell
nanostructures
are
powerful
platforms
for
the
development
of
novel
nanoscale
drug
delivery
systems
with
sustained
release
profiles.
Coaxial
electrospinning
is
facile
and
convenient
creating
medicated
core–shell
elaborate
designs
which
sustained-release
behaviors
molecules
can
be
intentionally
adjusted.
With
resveratrol
(RES)
as
a
model
poorly
water-soluble
cellulose
acetate
(CA)
PVP
polymeric
carriers,
brand-new
electrospun
nanostructure
was
fabricated
in
this
study.
The
guest
RES
host
CA
were
designed
to
have
reverse
gradient
distribution
within
nanostructures.
Scanning
electron
microscope
transmission
evaluations
verified
that
these
nanofibers
had
linear
morphologies,
without
beads
or
spindles,
an
obvious
double-chamber
structure.
X-ray
diffraction
patterns
Fourier
transform
infrared
spectroscopic
results
indicated
involved
components
highly
compatible
presented
amorphous
molecular
state.
In
vitro
dissolution
tests
new
structures
able
prevent
initial
burst
release,
extend
continuous-release
time
period,
reduce
negative
tailing-off
effect,
thus
ensuring
better
profile
than
traditional
blended
drug-loaded
nanofibers.
mechanism
underlying
influence
structure
RES/CA
on
proposed.
Based
proof-of-concept
demonstration,
series
advanced
functional
nanomaterials
similarly
developed
based
distributions
multi-chamber
Polymers,
Год журнала:
2024,
Номер
16(18), С. 2614 - 2614
Опубликована: Сен. 15, 2024
Polymeric
composites
for
manipulating
the
sustained
release
of
an
encapsulated
active
ingredient
are
highly
sought
after
many
practical
applications;
particularly,
water-insoluble
polymers
and
core–shell
structures
frequently
explored
to
manipulate
behaviors
drug
molecules
over
extended
time
period.
In
this
study,
electrospun
nanostructures
were
utilized
develop
a
brand-new
strategy
tailor
spatial
distributions
both
insoluble
polymer
(ethylcellulose,
EC)
soluble
(polyvinylpyrrolidone,
PVP)
within
nanofibers,
thereby
extended-release
loaded
ingredient,
ferulic
acid
(FA).
Scanning
electron
microscopy
transmission
assessments
revealed
that
all
prepared
nanofibers
had
linear
morphology
without
beads
or
spindles,
those
from
coaxial
processes
obvious
structure.
X-ray
diffraction
attenuated
total
reflectance
Fourier
transform
infrared
spectroscopic
tests
confirmed
FA
fine
compatibility
with
EC
PVP,
presented
in
amorphous
state.
vitro
dissolution
indicated
radical
(decreasing
shell
core)
PVP
(increasing
able
play
their
important
role
elaborately.
On
one
hand,
F3
advantages
homogeneous
composite
F1
higher
content
solutions
inhibit
initial
burst
provide
longer
period
release.
other
F2
core
negative
tailing-off
The
key
element
was
water
permeation
rates,
controlled
by
ratios
polymers.
new
based
on
structure
paves
way
developing
wide
variety
polymeric
heterogeneous
realizing
desired
functional
performances.
