International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(24), С. 13515 - 13515
Опубликована: Дек. 17, 2024
Graphene
and
its
various
derivatives,
known
as
graphene-based
nanomaterials
(GBNs),
hold
tremendous
potential
across
many
fields
due
to
their
exceptional
properties.
As
with
any
novel
material,
concerns
about
safety
have
emerged
alongside
widespread
production
use.
Several
studies
shown
that
GBNs
can
diverse
effects
on
cell
lines
organisms
under
different
exposure
conditions.
This
study
intends
evaluate
the
toxicity
of
few-layer
graphene
(FLG)
in
human
bronchial
BEAS-2B.
Cells
were
exposed
concentrations
FLG
for
24
h,
cyto-genotoxic,
oxidative,
inflammatory
evaluated.
We
found
an
increase
cytotoxicity
terms
death,
apoptosis,
membrane
damage
at
highest
concentration.
also
detected
a
slight
direct
DNA
percentage
comets.
Oxidative
was
observed
did
not
induce
notable
cytokine
release.
Overall,
this
suggests
cytotoxicity,
BEAS-2B,
particularly
high
concentrations.
These
findings
contribute
better
understanding
health
highlight
importance
considering
dose-dependent
when
assessing
GBNs.
ACS Omega,
Год журнала:
2024,
Номер
9(36), С. 37459 - 37504
Опубликована: Авг. 23, 2024
Gynecologic
cancers
are
a
significant
health
issue
for
women
globally.
Early
detection
and
successful
treatment
of
these
tumors
crucial
the
survival
female
patients.
Conventional
therapies
often
ineffective
harsh,
particularly
in
advanced
stages,
necessitating
exploration
new
therapy
options.
Nanotechnology
offers
novel
approach
to
biomedicine.
A
biosensor
utilizing
bionanotechnology
can
be
employed
early
tumor
identification
due
distinctive
physical
chemical
characteristics
nanoparticles.
Nanoparticles
have
been
rapidly
applied
field
gynecologic
malignancies,
leading
advancements
recent
years.
This
study
highlights
significance
nanoparticles
treating
gynecological
cancers.
It
focuses
on
using
precise
diagnosis
continuous
monitoring
disease,
innovative
imaging,
analytic
methods,
as
well
multifunctional
drug
delivery
systems
targeted
therapies.
review
examines
several
nanocarrier
systems,
such
dendrimers,
liposomes,
nanocapsules,
nanomicelles,
malignancies.
The
also
enhanced
therapeutic
potential
ligand-functionalized
nanoformulations
compared
nonfunctionalized
anoformulations.
In
conclusion,
text
discusses
constraints
future
prospects
chemotherapeutics.
will
offer
methods
diagnosing
Toxics,
Год журнала:
2024,
Номер
12(8), С. 565 - 565
Опубликована: Авг. 2, 2024
A
study
was
conducted
to
measure
aerosol
particles
emitted
from
laboratory
coats
(lab
coats)
under
vibration,
comparing
them
with
a
suit
and
shirt.
This
focused
on
ranging
0.3
μm
>10
μm.
Experimental
results
showed
that
lab
coat
vibration
increased
>5
while
reducing
submicron
particles.
The
(old
used)
exhibited
greater
particle
concentration
variations
compared
those
using
the
new
or
Contrastingly,
did
not
significantly
affect
concentrations.
These
findings
highlight
impact
of
concentrations
in
surrounding
air,
which
is
important
for
work
environments.
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(24), С. 13515 - 13515
Опубликована: Дек. 17, 2024
Graphene
and
its
various
derivatives,
known
as
graphene-based
nanomaterials
(GBNs),
hold
tremendous
potential
across
many
fields
due
to
their
exceptional
properties.
As
with
any
novel
material,
concerns
about
safety
have
emerged
alongside
widespread
production
use.
Several
studies
shown
that
GBNs
can
diverse
effects
on
cell
lines
organisms
under
different
exposure
conditions.
This
study
intends
evaluate
the
toxicity
of
few-layer
graphene
(FLG)
in
human
bronchial
BEAS-2B.
Cells
were
exposed
concentrations
FLG
for
24
h,
cyto-genotoxic,
oxidative,
inflammatory
evaluated.
We
found
an
increase
cytotoxicity
terms
death,
apoptosis,
membrane
damage
at
highest
concentration.
also
detected
a
slight
direct
DNA
percentage
comets.
Oxidative
was
observed
did
not
induce
notable
cytokine
release.
Overall,
this
suggests
cytotoxicity,
BEAS-2B,
particularly
high
concentrations.
These
findings
contribute
better
understanding
health
highlight
importance
considering
dose-dependent
when
assessing
GBNs.
