Self‐Reported Delayed Adverse Events and Flare Following COVID‐19 Vaccination Among Patients With Autoimmune Rheumatic Disease (AIRD) in Malaysia: Results From the COVAD‐2 Study

International Journal of Rheumatic Diseases, Год журнала: 2025, Номер 28(1)

Опубликована: Янв. 1, 2025

ABSTRACT Objectives To determine the prevalence of self‐reported delayed adverse events (DAEs), major AEs, and flares following COVID‐19 vaccinations among patients with autoimmune rheumatic diseases (AIRDs) in Malaysia. Methodology An electronically validated survey from vaccination (COVAD) study group was distributed July 2021 to healthy controls (HCs). The collected data on DAEs (any AE that persisted or occurred after 7 days vaccination), any early (MAEs), vaccination. Generalized estimating equation (GEE) models were performed factors associated repeated DAEs, MAEs, flares. Results A total 556 vaccines administered 204 subjects (150 AIRDs 54 HCs), 72.1% completing 3 doses. In multivariate GEE analysis, there a greater frequency minor versus HCs (OR 5.65, p = 0.052). occurrence MAEs higher (4.9% vs. 1.3%, 0.052), but it no longer significant model. group, BNT162b2 vaccine increased risk for (OR4.68, 0.02) while multimorbidity showed 8.25, 0.007). rate flare 10.6% analysis revealed systemic lupus erythematosus (SLE) (OR0.31, 0.03) hydroxychloroquine (HCQ) 0.16, < 0.001) protective against flare. Conclusion rates comparable other reported studies. Different types vaccines, underlying AIRDs, treatments may influence symptoms AEs postvaccination COVID‐19.

Язык: Английский

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Exploring the relationship between experience of vaccine adverse events and vaccine hesitancy: A scoping review

Human Vaccines & Immunotherapeutics, Год журнала: 2025, Номер 21(1)

Опубликована: Март 9, 2025

Fear of side effects is the main motive for vaccine refusal. However, before COVID-19 pandemic, little attention had been paid to actual experience adverse events and its relationship with hesitancy. This scoping review aimed analyze impact VH on EAE vice versa. We reviewed 55 articles. Most studies focused vaccination employed cross-sectional surveys self-reported indicators. These identified significant correlations between VH. Social cognitive models shed some light influence VH, while converse usually explained by nocebo effect that predominately accounts converse. emerging research field hampered inconsistencies in theoretical explanations, assessments relationship, measurements these two phenomena. A more comprehensive consideration individual experience, both objective subjective, would help develop effective communication strategies improve pharmacological surveillance.

Язык: Английский

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Who gets COVID-19 booster vaccination? Trust in public health institutions and promotion strategies post-pandemic in the Republic of Korea

Vaccine, Год журнала: 2023, Номер 41(50), С. 7560 - 7572

Опубликована: Ноя. 16, 2023

Язык: Английский

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State-level differentials in COVID-19 fatality: exploring age and sex disparities in Malaysia’s pandemic experience

Discover Social Science and Health, Год журнала: 2024, Номер 4(1)

Опубликована: Фев. 22, 2024

Abstract Issue COVID-19 has resulted in mortality worldwide and exposed vulnerabilities public health systems. Although countries have since transitioned to the endemic phase, it is nonetheless important identify inequities within populations improve strategies light of another crisis. Purpose This study aims offer deeper insights into sex age differentials fatality across different states Malaysia, from pandemic’s start country’s transition phase. Methodology Analyses utilized data on number cases deaths Malaysia January 2020 until April 2022. Case rate (CFR) was computed for each state based groups, four periods (January–December 2020, January–June 2021, July–December January–April 2022). Principal component analysis (PCA) uncovered patterns produced a multivariate visualization Malaysia. Findings revealed heterogeneity identified several vulnerable states, notably northern region (Kelantan, Perlis) East Coast (Sabah, Sarawak). A disparity apparent Kelantan as CFR among older females higher than their male counterparts. Sabah exhibited relatively child population 2021. Implication The findings deepened our understanding complexity, providing recommendations Malaysia’s government preparing future crises. case offers lessons need address regional disparities implement targeted protect subgroups.

Язык: Английский

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Persepsi Warga Tua Terhadap Komplikasi Kesihatan Selepas Pengambilan Vaksin COVID-19 di Malaysia

Jurnal Komunikasi Malaysian Journal of Communication, Год журнала: 2024, Номер 40(1), С. 221 - 247

Опубликована: Март 31, 2024

Pandemik COVID-19 telah menimbulkan risiko kesihatan yang ketara kepada populasi warga tua dan seterusnya, vaksinasi menjadi strategi awam penting untuk perlindungan mereka. Objektif kajian ini bertujuan memahami pengetahuan sedia ada dalam kalangan terhadap vaksin mengenalpasti kebimbangan komplikasi dirasakan tersebut. Temu bual mendalam dijalankan 15 berumur 60 tahun ke atas di Malaysia, mana menggunakan persampelan bola salji menganalisis pendapat daripada kumpulan informan menepati kriteria. Terdapat lapan tema utama terhasil analisis temu tersebut iaitu; (i) jenis kesan Pfizer, (ii) Astrazeneca, (iii) Sinovac, (iv) campuran, (v) mengambil melindungi diri keluarga secara terpaksa, (vi) meningkatkan sistem imuniti, (vii) pengambilan sebagai pilihan individu, dan, (viii) cetus kesihatan. Dapatan menjelaskan bahawa kebanyakan melengkapi kedua dos lebih awal pelancaran vaksin, apabila mereka fungsi imun badan dijangkiti wabak COVID-19. Namun, dapatan juga menemukan berhati-hati menerima penggalak terdapatnya banyak maklumat salah tular media sosial serta pengalaman buruk dihadapi selepas Selain itu, mendapati mempunyai percaya boleh jika vaksin. Justeru adalah amat bagi komunikasi masa depan menangani persepsi berbeza-beza menggalakkan keyakinan dikalangan sasaran ini. Kata kunci: Vaksin COVID-19, salah, kesihatan, tua, keraguan

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Just-world beliefs are associated with influenza vaccine intake intent in the United Arab Emirates: a cross-sectional study

Humanities and Social Sciences Communications, Год журнала: 2024, Номер 11(1)

Опубликована: Апрель 11, 2024

Abstract Although not a prime public health concern, seasonal influenza remains challenge in the United Arab Emirates (UAE). This problem is augmented by fact that percentage of population intending to take yearly vaccine relatively low. The purpose this study assess if knowledge and just-world beliefs have an impact on willingness receive vaccine. methodology relies multivariable logistic regression analysis establishing predictors intake intent parametric tests comparing variables across gender ethnicity. Results come out showing significant predictor intent. However, general belief just world has important implications for role religion curbing hesitancy UAE. Given are linked religiosity, authorities need consider relying religious leaders exhort faithful vaccines framing their exhortations context beliefs.

Язык: Английский

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A survey on Malaysian’s acceptance and perceptions towards COVID-19 booster dose

Saudi Pharmaceutical Journal, Год журнала: 2023, Номер 31(11), С. 101797 - 101797

Опубликована: Сен. 26, 2023

Progressive reopening of the economy and declaration COVID-19 as endemic has relaxed social distancing mask-wearing necessities in Malaysia. The Ministry Health Malaysia reported vaccination rate had reached 86.1% for first dose 84.3% second April 2023. However, uptake booster doses (third or fourth dose) is relatively lower at 68.6% 1.5%, respectively. A cross-sectional survey was undertaken to study acceptance perception Malaysians towards Peninsular with participants 18 years old above by distributing questionnaires public areas such government offices, major city train stations, airports. included elderly who were not technology savvy. Of 395 respondents, 69.4% accepted dose. results showed that smartphone usage (p = 0.019), living area 0.049), education level 0.006) significantly influenced among socio-demographic characteristics. Despite experiencing side effects from previous vaccination, 65.9% respondents still opted receive 0.019). highest deciding factor accepting need more clinical studies on (58.2%) 0.045). In conclusion, demonstrates greater emphasis updating providing regarding will increase public's

Язык: Английский

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Factors for hesitancy towards vaccination against COVID-19 among the adult population in Puducherry, India – a cross sectional study

BMC Public Health, Год журнала: 2023, Номер 23(1)

Опубликована: Ноя. 10, 2023

Vaccine hesitancy is a complex phenomenon that threatens global health. Present-day communication technology has paved the way for self-education but also contributed to infodemic surrounding vaccination. This resulted in pockets of people who are reluctant, refuse recommended vaccinations, or choose delay being vaccinated. The present study was designed estimate magnitude towards COVID-19 vaccination and determine its associated factors community.This cross-sectional conducted among 776 adults aged ≥ 18 years 15 clusters Puducherry district, India, between March 2022 May 2022. Face-to-face interviews were using validated, structured questionnaire. Socio-demographic variables, co-morbidities, attitudes vaccination, etc., expressed as frequencies percentages. dichotomized with median score cut-off reported proportion 95% confidence interval. Univariate multivariate analyses carried out vaccine hesitancy.The mean age participants 43.3 ± 14.8 years, majority female (67.0%). Nearly 92.4%, 74.4%, 0.5% received their first, second, precautionary doses, respectively, during period. Among unvaccinated, 93.2% unwilling receive any dose More than half hesitant according scale. Participants above 45 less hesitant, while those educated up school level, belonging upper socio-economic class, never tested past, having negative attitude significantly higher hesitancy.It imperative address by alleviating existing fears misconceptions community through efficient strategies win fight against current well future public health emergencies.

Язык: Английский

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To Vaccinate or Not? Perceived Benefits and Social Media Exposure as Predictors of COVID-19 Booster Jab Vaccination Practices with Self-Efficacy as Moderator

Deleted Journal, Год журнала: 2024, Номер 4(2), С. 148 - 163

Опубликована: Июль 31, 2024

Vaccination acceptance and its rates among Malaysians have generally been shown to be high during the COVID-19 pandemic; however, statistics from Ministry of Health Malaysia show that uptake for booster jab vaccination is significantly lower than rate when first dose vaccinations was offered. Thus, this study examined perceived benefits social media exposure practices Malaysians, moderated by self-efficacy. The used Stimulus-Response model as a theoretical basis. A quantitative method applied conducting an online survey gathering 300 valid data. employed non-probability sampling procedure combined purposive convenience samplings. data analysed using structural equation modeling via Partial Least Square Structural Equation Modeling (PLS-SEM). results affirmed positive significant relationship with practices. Meanwhile, moderating role self-efficacy established negative between practices, does not moderate path research findings provide opportunity more comprehensive educational programmes focus on consistency in providing public adequate knowledge communicating consistent health messages curb spread virus. Conclusion, implications, future pathways are also discussed.

Язык: Английский

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Navigating Vaccine Uncertainty: Anxiety and Fourth Dose Hesitancy Among Saudi Adults

Cureus, Год журнала: 2023, Номер unknown

Опубликована: Ноя. 13, 2023

Background The continuous evolution of new variants severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and early evidence declining effectiveness the third dose over time have generated anxiety hesitancy regarding vaccinations. current study aimed to assess levels willingness receive a fourth SARS-CoV-2 vaccine. Potential factors leading this reluctance were also assessed. Methodology This was cross-sectional cohort conducted among adult Saudi population. A questionnaire including demographic data, questions Generalized Anxiety Disorder (GAD-7) assessment, related accepting vaccine reasons for employed. Results Of 1,924 participants who responded, 1,033 males, 891 females. Among respondents, significant level toward receiving reported in 1,097 cases, representing 57% total, with varying degrees anxiety. Both gender age identified as co-factors contributing substantial portion participants, 1,369 individuals, accounting 71.2%, exhibited dose. Conclusions Our findings underscore pressing need targeted interventions combat alleviate associated anxieties, particularly As we persist confronting ongoing challenges brought about by evolving pandemic, it is crucial that customize our vaccination campaigns communication strategies tackle apprehensions hesitations population directly.

Язык: Английский

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