ACS Sustainable Chemistry & Engineering,
Год журнала:
2022,
Номер
10(43), С. 14212 - 14219
Опубликована: Окт. 17, 2022
A
series
of
zinc
indium
sulfide
(ZnIn2S4)
were
synthesized
by
solvothermal
methods
in
different
solvents.
After
characterizations,
the
ZnIn2S4
prepared
ethanol
(i.e.,
ZIS-1)
showed
highest
photocurrent
density.
With
ZIS-1
as
a
photocatalyst,
direct
C–H
azolation
N-heterocycles
including
quinoxalin-2(1H)-ones,
quinazoline,
and
2H-benzo[b][1,4]oxazin-2-ones
(32
examples)
was
realized
an
air
atmosphere
under
blue
light
(456
nm).
More
importantly,
microspherical
photocatalyst
is
stable
catalytic
process
can
be
used
at
least
five
times
while
reactivity
remains
unchanged.
In
addition,
this
practical
approach
also
applicable
to
some
other
complex
molecules
interest,
such
ibuprofen
isoxepac.
Organic Letters,
Год журнала:
2022,
Номер
24(11), С. 2232 - 2237
Опубликована: Март 11, 2022
Herein
we
report
a
site-selective
cyclopropanation
of
N-heterocyclic
carbene
(NHC)-borane
complexes
via
photochemical
transfer
reactions.
By
subtle
changes
to
the
reaction
conditions,
this
approach
can
be
further
extended
toward
difunctionalization
NHC-boranes
and
B-H
insertion
reaction.
Further
investigations
in
continuous-flow
applications
synthetic
transformations
proved
utility
method.
Theoretical
calculations
control
experiments
were
performed
explain
observed
selectivity.
Organic Chemistry Frontiers,
Год журнала:
2022,
Номер
9(13), С. 3486 - 3492
Опубликована: Янв. 1, 2022
A
metal-free
and
visible-light-promoted
strategy
has
been
developed
for
the
synthesis
of
S
-alkyl
dithiocarbamates
through
multicomponent
reactions
α-diazoesters,
amines
CS
2
.
ACS Catalysis,
Год журнала:
2022,
Номер
12(18), С. 11129 - 11136
Опубликована: Авг. 30, 2022
Herein,
we
report
visible
light
and
N-heterocyclic
carbene
(NHC)
jointly
promoted
multicomponent
transfer
reactions.
Under
the
optimized
reaction
conditions,
two
kinds
of
important
hydroxamic
acid
esters
were
obtained
in
good
yields
depending
on
media
used.
The
key
to
this
success
was
driven
by
blue
light-promoted
generation
free
species
fast
situ
formation
under
NHC-catalyzed
conditions.
mild
excellent
functional
group
tolerance,
useful
synthetic
transformations,
successful
modification
natural
products
drug
molecules
proved
utility
practicality
method.
ACS Catalysis,
Год журнала:
2023,
Номер
13(7), С. 4656 - 4666
Опубликована: Март 22, 2023
A
visible-light-induced
enantioselective
free
carbene
transfer
reaction
of
α-diazoesters
with
1,3-diketones
is
established
by
utilizing
a
chiral
bifunctional
guanidine-amide
organocatalyst.
Selective
insertion
into
the
C–C
or
C–H
bonds
1,3-diketone
could
be
achieved
bearing
different
steric
hindrances.
The
transformations
enable
preparation
series
1,4-diketones
quaternary
carbon
center
2-substituted-1,3-diketones
in
good
enantioselectivities.
On
basis
control
experiments
and
DFT
calculation,
stepwise
triplet
coupling
pathway
suggested.
possible
mechanism
proposed
to
explain
origin
high
enantioselectivities
via
hydrogen-bonds
electrostatic
interactions
catalyst.
Organic Letters,
Год журнала:
2023,
Номер
25(1), С. 169 - 173
Опубликована: Янв. 5, 2023
Cyclopropane-fused
lactones
are
highly
desirable
in
drug
and
natural
products
synthesis.
Herein,
we
report
on
a
photochemical,
chemoselective
reaction
of
aryldiazoacetates
with
allylic
alcohols
that
furnishes
cyclopropane-fused
lactone
skeletons
efficiently
one
step.
The
diastereoselectivity
the
protocol
was
precisely
controlled,
cyclopropanation
via
free
carbene
intermediate
followed
by
transesterification
constitutes
series
bicyclic
high
yield
without
formation
ether
byproducts
typical
O–H
insertion
reactions.
Organic Letters,
Год журнала:
2022,
Номер
24(37), С. 6834 - 6838
Опубликована: Сен. 8, 2022
A
visible-light
photocatalytic
regioselective
difunctionalization
of
alkenes
with
diazo
compounds
and
tert-butyl
nitrite
has
been
developed.
The
protocol
provides
an
efficient
approach
to
γ-oximino
esters
under
mild
conditions.
Significantly,
this
transformation
not
only
shows
the
good
compatibility
nucleophilic
electrophilic
but
also
displays
generating
alkyl
radicals
that
preferred
addition
over
nitroso
radicals.
Chemical Science,
Год журнала:
2022,
Номер
13(44), С. 13141 - 13146
Опубликована: Янв. 1, 2022
Photoexcitation
of
the
azodicarboxylates
results
in
a
radical
addition
reaction
with
diazoalkanes
and
formation
an
azomethine
ylide
to
allow
for
dipolar
cycloaddition
nitriles
give
1,2,4-triazole.
Chinese Journal of Chemistry,
Год журнала:
2022,
Номер
40(22), С. 2655 - 2662
Опубликована: Авг. 16, 2022
Comprehensive
Summary
A
general
transition‐metal‐free
visible‐light‐promoted
3‐acetalation
reaction
of
quinoxaline‐2(1
H
)‐ones
was
developed
under
mild
conditions.
By
employing
1,2,3,5‐tetrakis(carbazol‐9‐yl)‐4,6‐dicyanobenzene
(4CzIPN)
as
an
inexpensive
photocatalyst,
and
glyoxylic
acid
acetal
a
radical
source,
various
acetalated
were
constructed
in
moderate
to
good
yields.
Moreover,
the
versatility
this
protocol
is
highlighted
by
successful
application
late‐stage
modification
drug
molecules
functionality
transformations.
The
excellent
antitumor
activity
product
demonstrated
that
streamlined
sustainable
approach
could
have
emerged
powerful
strategy
for
structural
medicinal
chemistry.
