Cell Biochemistry and Biophysics, Год журнала: 2025, Номер unknown
Опубликована: Фев. 27, 2025
Язык: Английский
Scientific Reports, Год журнала: 2023, Номер 13(1)
Опубликована: Апрель 12, 2023
Abstract In recent years, mesoporous silica nanoparticles (MSNs) have been applied in various biomedicine fields like bioimaging, drug delivery, and antibacterial alternatives. MSNs could be manufactured through green synthetic methods as environmentally friendly sustainable synthesis approaches, to improve physiochemical characteristics for biomedical applications. the present research, we used Rutin (Ru) extract, a biocompatible flavonoid, reducing agent nonsurfactant template of Ag-decorated MSNs. Transmission electron microscopy (TEM), zeta-potential, x-ray powder diffraction (XRD), fourier transform infrared (FTIR) spectroscopy analysis, scanning (SEM), brunauer–emmett–teller (BET) energy-dispersive system (EDS) were evaluate physical characteristics. The antimicrobial properties evaluated against Staphylococcus aureus (S . aureus), Escherichia coli ( E coli), also different types candida. cytotoxicity test was performed by using MTT assay. Based on findings, significant efficacy Ru-Ag-decorated both gram positive negative bacteria fungi detected well acceptable safety low even at lower concentrations. Our results given straightforward cost-effective method fabricating biodegradable applications these domains appear promising.
Язык: Английский
Процитировано
69
Journal of Drug Delivery Science and Technology, Год журнала: 2023, Номер 85, С. 104541 - 104541
Опубликована: Май 20, 2023
Язык: Английский
Процитировано
47
Inorganic Chemistry Communications, Год журнала: 2024, Номер 161, С. 112006 - 112006
Опубликована: Янв. 5, 2024
Язык: Английский
Процитировано
38
Applied Physics A, Год журнала: 2024, Номер 130(5)
Опубликована: Апрель 4, 2024
Язык: Английский
Процитировано
25
BioNanoScience, Год журнала: 2025, Номер 15(1)
Опубликована: Янв. 10, 2025
Язык: Английский
Процитировано
2
Applied Nanoscience, Год журнала: 2022, Номер 13(6), С. 4395 - 4405
Опубликована: Ноя. 27, 2022
Язык: Английский
Процитировано
57
Pharmaceutics, Год журнала: 2023, Номер 15(3), С. 879 - 879
Опубликована: Март 8, 2023
Despite recent advances, cancer remains the primary killer on a global scale. Numerous forms of research have been conducted to discover novel and efficient anticancer medications. The complexity breast is major challenge which coupled with patient-to-patient variations heterogeneity between cells within tumor. Revolutionary drug delivery expected provide solution that challenge. Chitosan nanoparticles (CSNPs) prospects as revolutionary system capable enhancing activity reducing negative impacts normal cells. use smart systems (SDDs) delivering materials improve bioactivity NPs understand intricacies has garnered significant interest. There are many reviews about CSNPs present various points view, but they not yet described series in therapy from cell uptake death. With this description, we will more complete picture for designing preparations SDDs. This review describes SDDSs, targeting stimulus response using their mechanism. Multimodal chitosan SDDs medication therapeutic results.
Язык: Английский
Процитировано
30
Pharmaceutics, Год журнала: 2023, Номер 15(5), С. 1406 - 1406
Опубликована: Май 4, 2023
Cancer is a leading cause of death worldwide, and the main treatment methods for this condition are surgery, chemotherapy, radiotherapy. These invasive can severe adverse reactions among organisms, so nanomaterials increasingly used as structures anticancer therapies. Dendrimers type nanomaterial with unique properties, their production be controlled to obtain compounds desired characteristics. polymeric molecules in cancer diagnosis through targeted distribution some pharmacological substances. have ability fulfill several objectives therapy simultaneously, such targeting tumor cells that healthy tissue not affected, controlling release agents microenvironment, combining strategies based on administration potentiate effect photothermal or photodynamic therapy. The purpose review summarize highlight possible uses dendrimers regarding oncological conditions.
Язык: Английский
Процитировано
29
Environmental Research, Год журнала: 2023, Номер 228, С. 115886 - 115886
Опубликована: Апрель 16, 2023
Язык: Английский
Процитировано
24
Pharmaceuticals, Год журнала: 2024, Номер 17(3), С. 315 - 315
Опубликована: Фев. 28, 2024
Cancer continues to pose one of the most critical challenges in global healthcare. Despite wide array existing cancer drugs, primary obstacle remains selectively targeting and eliminating cells while minimizing damage healthy ones, thereby reducing treatment side effects. The revolutionary approach utilizing nanomaterials for delivering therapeutic agents has significantly enhanced efficacy safety chemotherapeutic drugs. This crucial shift is attributed unique properties nanomaterials, enabling nanocarriers transport tumor sites both passive active modes, drug elimination from delivery systems. Furthermore, these can be designed respond internal or external stimuli, thus facilitating controlled release. However, production nanomedications therapy encounters various that impede progress this field. review aims provide a comprehensive overview current state nanomedication treatment. It explores variety focusing on their are overcoming limitations conventional chemotherapy. Additionally, delves into functionalities nanocarriers, highlighting significant impact evolution nanomedicine. also critically assesses recent advancements systems, covering range innovative methodologies. Finally, succinctly addresses encountered developing nanomedications, offering insightful perspectives guide future research
Язык: Английский
Процитировано
9