Cell Biochemistry and Biophysics, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 27, 2025
Language: Английский
Scientific Reports, Journal Year: 2023, Volume and Issue: 13(1)
Published: April 12, 2023
Abstract In recent years, mesoporous silica nanoparticles (MSNs) have been applied in various biomedicine fields like bioimaging, drug delivery, and antibacterial alternatives. MSNs could be manufactured through green synthetic methods as environmentally friendly sustainable synthesis approaches, to improve physiochemical characteristics for biomedical applications. the present research, we used Rutin (Ru) extract, a biocompatible flavonoid, reducing agent nonsurfactant template of Ag-decorated MSNs. Transmission electron microscopy (TEM), zeta-potential, x-ray powder diffraction (XRD), fourier transform infrared (FTIR) spectroscopy analysis, scanning (SEM), brunauer–emmett–teller (BET) energy-dispersive system (EDS) were evaluate physical characteristics. The antimicrobial properties evaluated against Staphylococcus aureus (S . aureus), Escherichia coli ( E coli), also different types candida. cytotoxicity test was performed by using MTT assay. Based on findings, significant efficacy Ru-Ag-decorated both gram positive negative bacteria fungi detected well acceptable safety low even at lower concentrations. Our results given straightforward cost-effective method fabricating biodegradable applications these domains appear promising.
Language: Английский
Citations
69
Journal of Drug Delivery Science and Technology, Journal Year: 2023, Volume and Issue: 85, P. 104541 - 104541
Published: May 20, 2023
Language: Английский
Citations
47
Inorganic Chemistry Communications, Journal Year: 2024, Volume and Issue: 161, P. 112006 - 112006
Published: Jan. 5, 2024
Language: Английский
Citations
38
Applied Physics A, Journal Year: 2024, Volume and Issue: 130(5)
Published: April 4, 2024
Language: Английский
Citations
25
BioNanoScience, Journal Year: 2025, Volume and Issue: 15(1)
Published: Jan. 10, 2025
Language: Английский
Citations
2
Applied Nanoscience, Journal Year: 2022, Volume and Issue: 13(6), P. 4395 - 4405
Published: Nov. 27, 2022
Language: Английский
Citations
57
Pharmaceutics, Journal Year: 2023, Volume and Issue: 15(3), P. 879 - 879
Published: March 8, 2023
Despite recent advances, cancer remains the primary killer on a global scale. Numerous forms of research have been conducted to discover novel and efficient anticancer medications. The complexity breast is major challenge which coupled with patient-to-patient variations heterogeneity between cells within tumor. Revolutionary drug delivery expected provide solution that challenge. Chitosan nanoparticles (CSNPs) prospects as revolutionary system capable enhancing activity reducing negative impacts normal cells. use smart systems (SDDs) delivering materials improve bioactivity NPs understand intricacies has garnered significant interest. There are many reviews about CSNPs present various points view, but they not yet described series in therapy from cell uptake death. With this description, we will more complete picture for designing preparations SDDs. This review describes SDDSs, targeting stimulus response using their mechanism. Multimodal chitosan SDDs medication therapeutic results.
Language: Английский
Citations
30
Pharmaceutics, Journal Year: 2023, Volume and Issue: 15(5), P. 1406 - 1406
Published: May 4, 2023
Cancer is a leading cause of death worldwide, and the main treatment methods for this condition are surgery, chemotherapy, radiotherapy. These invasive can severe adverse reactions among organisms, so nanomaterials increasingly used as structures anticancer therapies. Dendrimers type nanomaterial with unique properties, their production be controlled to obtain compounds desired characteristics. polymeric molecules in cancer diagnosis through targeted distribution some pharmacological substances. have ability fulfill several objectives therapy simultaneously, such targeting tumor cells that healthy tissue not affected, controlling release agents microenvironment, combining strategies based on administration potentiate effect photothermal or photodynamic therapy. The purpose review summarize highlight possible uses dendrimers regarding oncological conditions.
Language: Английский
Citations
29
Environmental Research, Journal Year: 2023, Volume and Issue: 228, P. 115886 - 115886
Published: April 16, 2023
Language: Английский
Citations
24
Pharmaceuticals, Journal Year: 2024, Volume and Issue: 17(3), P. 315 - 315
Published: Feb. 28, 2024
Cancer continues to pose one of the most critical challenges in global healthcare. Despite wide array existing cancer drugs, primary obstacle remains selectively targeting and eliminating cells while minimizing damage healthy ones, thereby reducing treatment side effects. The revolutionary approach utilizing nanomaterials for delivering therapeutic agents has significantly enhanced efficacy safety chemotherapeutic drugs. This crucial shift is attributed unique properties nanomaterials, enabling nanocarriers transport tumor sites both passive active modes, drug elimination from delivery systems. Furthermore, these can be designed respond internal or external stimuli, thus facilitating controlled release. However, production nanomedications therapy encounters various that impede progress this field. review aims provide a comprehensive overview current state nanomedication treatment. It explores variety focusing on their are overcoming limitations conventional chemotherapy. Additionally, delves into functionalities nanocarriers, highlighting significant impact evolution nanomedicine. also critically assesses recent advancements systems, covering range innovative methodologies. Finally, succinctly addresses encountered developing nanomedications, offering insightful perspectives guide future research
Language: Английский
Citations
9