FEMS Microbiology Reviews,
Год журнала:
2016,
Номер
40(6), С. 961 - 979
Опубликована: Авг. 26, 2016
Assemblages
of
microbial
genotypes
growing
together
can
display
surprisingly
complex
and
unexpected
dynamics
result
in
community-level
functions
behaviors
that
are
not
readily
expected
from
analyzing
each
genotype
isolation.
This
complexity
has,
at
least
part,
inspired
a
discipline
synthetic
ecology.
Synthetic
ecology
focuses
on
designing,
building
the
dynamic
behavior
‘ecological
circuits’
(i.e.
set
interacting
genotypes)
understanding
how
properties
emerge
as
consequence
those
interactions.
In
this
review,
we
discuss
typical
objectives
main
advantages
rationales
using
assemblages.
We
then
summarize
recent
findings
current
investigations.
particular,
focus
causes
consequences
interplay
between
different
illustrate
simple
interactions
create
promote
properties.
finally
propose
distinguishing
active
passive
accounting
for
pervasiveness
competition
improve
existing
frameworks
designing
predicting
The ISME Journal,
Год журнала:
2016,
Номер
10(11), С. 2557 - 2568
Опубликована: Март 29, 2016
Abstract
The
importance
of
microbial
communities
(MCs)
cannot
be
overstated.
MCs
underpin
the
biogeochemical
cycles
earth’s
soil,
oceans
and
atmosphere,
perform
ecosystem
functions
that
impact
plants,
animals
humans.
Yet
our
ability
to
predict
manage
function
these
highly
complex,
dynamically
changing
is
limited.
Building
predictive
models
link
MC
composition
a
key
emerging
challenge
in
ecology.
Here,
we
argue
addressing
this
requires
close
coordination
experimental
data
collection
method
development
with
mathematical
model
building.
We
discuss
specific
examples
where
model–experiment
integration
has
already
resulted
important
insights
into
structure.
also
highlight
research
questions
still
demand
better
experiments
models.
such
needed
achieve
significant
progress
understanding
dynamics
function,
make
practical
suggestions
as
how
could
achieved.
