Представлен анализ трех эпидемиологических исследований (ЭПОХА-ХСН, ЭПОХА-Госпиталь-ХСН и ЭПОХА-Декомпенсация-ХСН). За 16 лет в РФ распространенность хронической сердечной недостаточности (ХСН) выросла достоверно от 4,9% (1998г) до 10,2% (2014г), р-0,01. При этом число пациентов с ХСН ІІІ-ІѴ ФК увеличилось значительнее: от 1,2% (1998г) до 4,1% (2014г), р-0,002. Это произошло за счет достоверного увеличения возраста выборки больных с 64,0±11,9 лет (1998г) по 69,9±12,2 лет (2014г), р-0,02; увеличения весомости этиологических причин ишемической болезни сердца и перенесенного инфаркта миокарда. Общая смертность больных любого ХСН составляет 6% в год. Показатель зависит от низкой частоты назначений блокаторов РААС и бета-блокаторов на амбулаторном этапе с использованием низких доз …
Kardiologiia,
Год журнала:
2021,
Номер
61(4), С. 4 - 14
Опубликована: Май 6, 2021
Aim
To
study
the
etiology
and
dynamics
of
prevalence
mortality
CHF;
to
evaluate
treatment
coverage
such
patients
in
a
representative
sample
European
part
Russian
Federation
for
20-year
period.
Material
methods
A
followed
up
2002
through
2017
(n=19
276);
population
Nizhny
Novgorod
region
examined
1998
(n=1922).
Results
During
observation
period
since
2002,
incidence
major
CHF
symptoms
(tachycardia,
edema,
shortness
breath,
weakness)
tended
decrease
while
cardiovascular
diseases
has
statistically
significantly
increased.
from
2017,
I-IV
functional
class
(FC)
increased
6.1
%
8.2
whereas
III-IV
FC
1.8
3.1
%.
The
main
causes
development
remained
arterial
hypertension
ischemic
heart
disease;
role
myocardial
infarction
diabetes
mellitus
as
was
noted.
For
analyzed
period,
number
components
basic
therapy
with
increased,
which
probably
accounts
slower
increase
disease
by
2007–2017.
prognosis
unfavorable:
I-II
CHF,
median
survival
8.4
(95
CI:
7.8–9.1)
years
3.8
3.4–4.2)
years.
Russian Journal of Cardiology,
Год журнала:
2023,
Номер
28(10), С. 5593 - 5593
Опубликована: Сен. 5, 2023
Aim.
To
describe
demographic
and
clinical
laboratory
characteristics,
concomitant
diseases
drug
therapy
of
outpatients
with
heart
failure
(HF)
in
the
Russian
Federation.
Material
methods.
An
interim
analysis
a
prospective
observational
multicenter
registry
study
patients
chronic
Federation
("PRIORITET-CHF")
was
performed.
The
included
HF
followed
by
general
practitioner
or
cardiologist.
Results.
Data
from
6255
were
analyzed
(31,3%
sample;
median
age,
65
years;
men,
65%).
reduced
ejection
fraction
(HFrEF)
diagnosed
42,4%,
preserved
EF
—
31,9%.
In
addition,
57,4%
characterized
NYHA
class
II
HF.
most
common
causes
hypertension,
coronary
artery
disease,
atrial
fibrillation
flutter.
Of
diseases,
doctors
often
reported
kidney
disease
(CKD)
(43,2%),
obesity
(37,8%)
diabetes
(26,7%)
Conclusion.
Federation,
among
HF,
there
domination
HFrEF
phenotype,
II.
relatively
young
mean
age
frequent
associations
cardiovascular
risk
factors
underscore
importance
timely
prevention
initiatives.
identified
high
proportion
CKD
requires
special
attention
separate
analysis.
Despite
prescription
rate
certain
classes
diseasemodifying
for
optimal
quadruple
electrophysiological
treatments
is
insufficient.
Kardiologiia,
Год журнала:
2020,
Номер
60(4), С. 91 - 100
Опубликована: Май 4, 2020
Background
Mortality
from
chronic
heart
failure
(CHF)
remains
high
and
entails
serious
demographic
losses
worldwide.
The
most
vulnerable
group
is
patients
after
acute
decompensated
HF
(ADHF)
who
have
a
risk
of
unfavorable
outcome.Aim
To
analyze
risks
all-cause
death
(ACD),
cardiovascular
(CVD),
recurrent
ADHF
in
CHF
during
two
years
following
long-term
follow-up
with
specialized
medical
care
real-life
clinical
practice.Material
methods
study
successively
included
942
ADHF.
510
continued
out-patient
treatment
center
(CHFTC)
(group
1)
432
refused
the
management
CHFTC
were
managed
clinics
at
place
patient's
residence
2).
Causes
determined
based
on
inpatient
hospital
records,
postmortem
reports,
or
outpatient
records.
Cases
ACD,
CVD,
ADHF,
composite
index
(CVD
ADHF)
analyzed.
Statistical
analysis
was
performed
software
package
Statistica
7.0
for
Windows,
SPSS,
statistical
R.Results
Patients
2
older,
more
frequently
had
functional
class
(FC)
III
less
FC
I
compared
to
1.
Women
preserved
left
ventricular
ejection
fraction
(LV
EF)
prevailed
both
groups.
Results
Cox
proportional
hazards
model
mortality
showed
that
belonging
an
independent
predictor
increased
(р<0.001).
An
increase
CCS
score
by
1
also
Baseline
LV
EF
did
not
influence
any
model.
Female
gender
higher
value
6-min
walk
test
(6MW)
independently
decreased
all
outcomes
except
CVD.
systolic
BP
10
mm
Hg
reduced
fatal
outcomes.
At
groups
1,
ACD
29.9
%
10.2
%,
(OR,
3.7;
95
CI:
2.6-5.3;
p
<0.001),
CVD
10.4
1.9
5.9;
2.8-12.4;
p<0.001),
18.1
6.0
3.5;
2.2-5.5;
25.2
7.7
4.1;
2.7-6.1;
р<0.001).
Analysis
period
(3
6
months
years)
difference
between
outcome
maximal
first
months.Conclusion
system
reduces
discharge
vulnerability
impaired
prognosis
whereas
baseline
Protective
factors
female
values
6MW
BP.
Russian Journal of Cardiology,
Год журнала:
2021,
Номер
26(6), С. 4490 - 4490
Опубликована: Июль 16, 2021
Heart
failure
(HF)
significantly
worsens
the
patient
quality
of
life
and
leads
to
disability
their
significant
part,
as
well
increases
risk
death,
which
in
turn
causes
economic
damage.
Aim
.
To
assess
annual
socio-economic
impact
HF
Russia.
Material
methods
HF,
a
model
was
developed,
assessed
number
patients
seeking
medical
care
(data
from
epidemiological
studies),
those
with
disabilities
mortality
rate
among
them.
We
also
evaluated
costs
drug
therapy
government
procurement
reports)
hospitalization
compulsory
health
insurance
tariffs),
social
benefits
due
disability,
death
on
gross
domestic
product.
Data
prescription
rate,
hospitalizations
obtained
Russian
registries
cardiovascular
diseases.
Using
foreign
study,
family
caregiving
were
calculated.
Results
According
modeling
data,
there
are
7,1
million
people
In
this
case,
context
spending,
is
RUB
81,86
billion,
including
18,6
direct
nonmedical
47,1
indirect
16,2
billion.
The
72,4
structure
expenses,
73,6%
costs,
while
main
borne
by
patients,
since
only
part
them
(19,6%)
receive
necessary
medications
within
assistance
programs.
reduced
ejection
fraction,
56%
higher
than
preserved
fraction.
Conclusion
burden
state.
Improving
healthcare
system
for
category
preferential
provision,
will
reduce
HF-related
mortality,
and,
accordingly,
state
society.
Russian Journal of Cardiology,
Год журнала:
2024,
Номер
29(11), С. 6162 - 6162
Опубликована: Окт. 24, 2024
Russian
Society
of
Cardiology
(RSC)
With
the
participation:
National
Myocardial
Diseases
and
Heart
Failure,
Failure
Specialists,
Scientific
Medical
Internal
Medicine
Endorsed
by
Research
Practical
Council
Ministry
Health
Federation
(12.09.2024)
Bulletin of the Medical Institute REAVIZ (REHABILITATION DOCTOR AND HEALTH),
Год журнала:
2025,
Номер
15(1), С. 72 - 78
Опубликована: Март 20, 2025
The
aim
of
the
study
:
to
divide
a
heterogeneous
group
patients
with
chronic
heart
failure,
taking
into
account
parameters
body
composition
and
severity
painful
symptoms.
Object
methods
.
involved
298
CHF.
was
assessed:
presence
sarcopenia
obesity
(with
calculation
muscle
mass
index),
functional
class,
left
ventricular
ejection
fraction,
markers
galectin-3,
hsCRP
sodium
uretic
peptide,
Bartel
index.
A
10-point
Edmont
scale
used
assess
two-stage
cluster
analysis
performed.
Results
Three
clusters
were
identified
in
patient
structure:
share
first
overall
structure
23.2%,
second
–
61.1%,
third
15.8%.
It
determined
that
includes
sarcopenic
obesity.
They
are
characterized
by
maximum
galectin
level
fraction
sample.
have
low
walking
speed,
dynamometry,
NТ-proBNP.
intermediate
position
is
occupied
(patients
isolated
disorder
or
without
it).
high
dynamometry
indicators,
6-minute
test
value,
Barthel
Patients
people
weight
sarcopenia.
Sarcopenia
Fast
questionnaire
T6W
indicators
significantly
reduced
fractions
NТ-proBNP
level.
most
pronounced
pain
fatigue
lowest
depression.
In
cluster,
pain,
fatigue,
drowsiness,
nausea,
shortness
breath,
anxiety,
well-being
expressed
much
less
than
other
clusters.
And
highest
appetite
disorders,
depression,
deterioration
well-being.
Conclusions
distressing
symptoms
varies
depending
on
and,
accordingly,
patient's
composition,
which
can
be
constructing
algorithms
for
providing
palliative
care