The Effect of Meal Replacement on Weight Loss According to Calorie-Restriction Type and Proportion of Energy Intake: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Journal of the Academy of Nutrition and Dietetics, Год журнала: 2021, Номер 121(8), С. 1551 - 1564.e3

Опубликована: Июнь 16, 2021

Portion control is a useful component of weight reduction interventions and meal replacement (MR) plans represent promising strategy for portion control. Research performed with pooled data on the effect MR according to various characteristics remains scarce.Our aim was assess effects MR-based diets compared food-based loss, calorie-restriction types energy intake proportions from MR.Electronic databases (Cochrane Central Register Controlled Trials, PubMed, Embase, Information Sharing Service) were searched randomized controlled trials loss results calorie-restricted January 2000 May 2020. Standardized mean differences (Hedges' g) all study outcomes calculated using random-effects model. Heterogeneity quantified by Q test I2. Publication bias assessed funnel plot trim fill method. Both (MR control) separated into very-low-energy low-energy (LEDs). A meta-analysis variance conducted dividing patient-related factors treatment-related subgroups. In multivariable meta-regressions, background variables selected first, after which main independent included.Twenty-two studies involving 24 1,982 patients who overweight or obese included. The size in LED small, favoring g = 0.261; 95% CI 0.156 0.365; I2 21.9; 0.0 53.6). Diets including ≥60% total daily had medium regard among groups 0.545; 0.260 0.830; 42.7; 80.8).The superior LED, receiving greatest loss.

Язык: Английский

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Food Culture of the Russian Population: Results of a Sociological Survey

ЗДОРОВЬЕ НАСЕЛЕНИЯ И СРЕДА ОБИТАНИЯ - ЗНиСО / PUBLIC HEALTH AND LIFE ENVIRONMENT, Год журнала: 2022, Номер unknown, С. 13 - 22

Опубликована: Фев. 1, 2022

Introduction: Food culture is one of the basic principles a healthy lifestyle. Malnutrition has numerous adverse health effects, overweight and obesity being most prevalent ones. Yet, many people find it quite difficult to mind their diet and, in fact, care little about choice safe foodstuffs or cooking techniques. In this respect, fast food poses certain danger. The objective our study was analyze evaluate nutritional practices representatives different socio-demographic groups Russian establish reasons for lack eating habits. Methods: Within framework research, an all-Russian sociological survey conducted using method in-home personal interview. from April 8 19, 2021 30 regions Russia. sample size 1,500 aged 18 years older. Results: Rational nutrition not yet become daily practice Russians. pace life busyness population are obstacle meal consumption regularity. Still, respondents report main criteria choosing product include its price, quality, taste, benefit. At same time, price recently stronger determinant, especially low-income retired citizens. Fast restaurant chains help save time money spent on meals increasingly popular among Conclusion: It expedient stimulate interest issues terms quantitative qualitative composition encourage habit regular meals. This relevant young people, who often very careless health.

Язык: Английский

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TEMPORAL DYNAMICS OF THE MORPHOLOGICAL CHARACTERISTICS OF THE ABKHAZIAN CHILDREN AND ADOLESCENTS IN CHANGING LIVING CONDITIONS OF THE POPULATION

Moscow University Anthropology Bulletin (Vestnik Moskovskogo Universiteta Seria XXIII Antropologia), Год журнала: 2024, Номер 1/2024, С. 49 - 66

Опубликована: Апрель 12, 2024

Introduction. The purpose of the work is to determine temporal variability morphological characteristics urban Abkhazian children and adolescents in context changing living conditions. Materials methods. For first time, parameters some signs Abkhaz 10-17 years old from city Sukhum (Republic Abkhazia) 2012 were presented. Intergenerational analysis somatic development indicators was carried out for boys girls (the total number examined 1,651 people). Surveys 2005 conducted under a single protocol included set measuring descriptive features. Results. During considered time period 17 years, stability longitudinal proportions skeleton noted. girls, trend has been established towards flattening shape chest, narrowing shoulder diameter. Similar changes transverse skeletal are trending. observed discrepancies two samples during ecosensitive growth periods. Stunts caused by effects difficult conditions early examination compensated end period. Two achieve similar definition at different rates. younger sample offset continued rates until Over considered, labile components catfish have changed greater extent, determining girth body. children, temporary an increase abdominal fat deposition decrease subcutaneous on limbs determined. Conclusion. sex specificity characteristic systems observed. Changes dimensions determined change topography according "truncal" type, which probably result adaptation new conditions, traditional lifestyle population. review, minor system noted adolescents. Significant affected fatty component soma: there truncal type. teenagers, gender secular dynamics various established. study results demonstrate important role environmental factors status genetically stable

Язык: Английский

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OBESITY AS A REFLECTION OF PSYCHO-EMOTIONAL DISORDERS: FOCUS ON PHARMACOTHERAPY

Pharmacy & Pharmacology, Год журнала: 2022, Номер 10(1), С. 19 - 30

Опубликована: Март 6, 2022

Obesity is a vivid example of multifactorial disease. In its development, not only the discrepancy between energy intake and expenditure but also various neurohumoral mechanisms, as well external socio-economic psychosocial factors, play important roles. One frequent options for combining psychoemotional disorders with obesity development certain types eating in patient. this regard, actual problem to find optimal therapeutic prophylactic strategy management such patients. The aim work analyze literature data on features pathogenetic mechanisms against background that are realized through disorders, identify possibilities using sibutramine carry out pharmacological correction these pathological conditions. Materials methods. process selecting materials writing review article, following databases were uses: PubMed, Scopus, Web Science, Google Scholar, ScienceDirect, etc. search carried out, was based publications period from 2009 2020. words phrases chosen parameters selection: obesity, psycho-emotional sibutramine. Results. This summarizes main aspects unite both metabolic disorders. A modern classification taking into account latest domestic international recommendations professional communities, given. Eating considered detail, their socio-psychological psychiatric classifications prospect choosing managing patients assessed, depending presence Conclusion. Thus, combined drug containing metformin registered Russian Federation effective, safe can be used alimentary contraindications.

Язык: Английский

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Anti-Inflammatory, Antioxidant, and WAT/BAT-Conversion Stimulation Induced by Novel PPAR Ligands: Results from Ex Vivo and In Vitro Studies

Pharmaceuticals, Год журнала: 2023, Номер 16(3), С. 346 - 346

Опубликована: Фев. 24, 2023

Activation of peroxisome proliferator-activated receptors (PPARs) not only regulates multiple metabolic pathways, but mediates various biological effects related to inflammation and oxidative stress. We investigated the four new PPAR ligands containing a fibrate scaffold—the agonists (1a (αEC50 1.0 μM) 1b (γEC50 0.012 μM)) antagonists (2a (αIC50 6.5 2b 0.98 μM, with weak antagonist activity on γ isoform))—on proinflammatory stress biomarkers. The 1a-b 2a-b (0.1–10 were tested isolated liver specimens treated lipopolysaccharide (LPS), levels lactate dehydrogenase (LDH), prostaglandin (PG) E2, 8-iso-PGF2α measured. these compounds gene expression adipose tissue markers browning, PPARα, PPARγ, in white adipocytes, evaluated as well. found significant reduction LPS-induced LDH, PGE2, after 1a treatment. On other hand, decreased LDH activity. Compared control, stimulated uncoupling protein 1 (UCP1), PR-(PRD1-BF1-RIZ1 homologous) domain 16 (PRDM16), deiodinase type II (DIO2), PPARα PPARγ expression, 3T3-L1 cells. Similarly, increased UCP1, DIO2, expression. caused PRDM16, DIO2 when at 10 μM. In addition, significantly A was also novel agonist might be promising lead compound represents valuable pharmacological tool for further assessment. could play minor role regulation inflammatory pathways.

Язык: Английский

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The Correlation Between Body Weight and Arterial Blood Pressure in 11 and 15 Years Old Children: Retrospective Cross-Sectional Study

Педиатрическая фармакология, Год журнала: 2019, Номер 16(4), С. 211 - 215

Опубликована: Дек. 25, 2019

Background . Children’s body weight is the predictor of pathologic elevation arterial blood pressure (ABP) in adult life. The aim study to divide data on and ABP adolescents find correlations between them. Methods. randomised 11 15 years old pupils from general education institutions was carried out. 16 months research executed 9 different regions country (one region every federal district 5 schools (with juniors seniors) each were randomly selected). In addition measurement (three times by Korotkov’s method) (using bathroom scales) all children examined group pediatric specialists (pediatrician, gastroenterologist, allergologist, otolaryngologist, ophthalmologist, neurologist, psychologist, cognitive specialist, orthopedic traumatologists, nephrologist, ultrasound laboratory diagnostic specialist). Results. included 1911 teenagers. correlation (p<0,010 for groups) systolic/diastolic revealed boys at age (r=0,394/0,206) (r=0,231/0,185) girls same (r=0,330/0,227 r=0.228/0.148 respectively). Conclusion significant levels systolic diastolic has been revealed.

Язык: Английский

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ANTIOXIDANT STATUS IN ADOLESCENTS WITH IDIOPATHIC OBESITY

Современные проблемы науки и образования (Modern Problems of Science and Education), Год журнала: 2023, Номер №5 2023, С. 82 - 82

Опубликована: Янв. 1, 2023

АНТИОКСИДАНТНЫЙ СТАТУС У ПОДРОСТКОВ ПРИ ИДИОПАТИЧЕСКОМ ОЖИРЕНИИНикитина О.А.

Язык: Русский

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OBESITY AS A SOCIAL PROBLEM

Polythematic Online Scientific Journal of Kuban State Agrarian University, Год журнала: 2017, Номер unknown

Опубликована: Ноя. 30, 2017

Язык: Английский

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Occupational health risks in mining dump truck drivers

Hygiene and Sanitation, Год журнала: 2022, Номер 101(8), С. 969 - 975

Опубликована: Сен. 14, 2022

Introduction. In recent years, the mining dump truck drivers have consistently reported high rates of occupational morbidity. The aim study was a retrospective pathology development in at apatite open pits Kola Peninsula. Material and methods. A analysis carried out six hundred forty three drivers. Its starting point results medical examination 2008, 2009-2020, newly detected diseases were studied. Results. During 12 172 including vibration disease (n=63), radiculopathy (n=54), reflex syndromes (n=36), sensorineural hearing loss (n=19) diagnosed for first time 105 (16.3%) 85 (49.4%) cases due to increased severity work (class 3.1-3.2). 66 (38.4%) cases, cause whole-body 3.1-3.2), 19 (11.0%) - noise 2 (1.2%) hand-arm 3.1). risk developing musculoskeletal by vertebral osteochondrosis (RR=1.78; CI 1.21-2.60; p=0.004), deforming osteoarthritis (RR=2.35; 1.41-3, 91; p=0.001), arthralgia (RR = 3.12; 1.66-5.86; p<0.0001), cervicalgia (RR=3.29; 1.48-7.32 ; p 0.002). Occupational exposure (Z57.0) (RR=2.61; 1.31-5.19; p=0.005). Limitations. impossibility completely eliminating diagnosis an who left observation group permanent residence other regions country. Conclusion. health is determined length service, work, impact noise, concomitant ear diseases, which must be taken into account prevention diseases.

Язык: Английский

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MORTALITY OF THE ADULT POPULATION OF MOSCOW AND THE RUSSIAN FEDERATION FROM OBESITY-ASSOCIATED CAUSES

Problems of Social Hygiene Public Health and History of Medicine, Год журнала: 2022, Номер 30(s1), С. 1109 - 1115

Опубликована: Ноя. 17, 2022

Currently, obesity is considered one of the most significant health problems, representing a common chronic disease leading to development severe comorbidities, accompanied by loss disability-adjusted life years and high mortality. Due fact that risk factors for number non-communicable diseases, such as diseases circulatory system, endocrine system malignant neoplasms.assessment adult mortality dynamics from obesity-associated causes in Moscow compared Russian Federation 2011-2020.data analytic package FAISS (internal use program): standardized rates population whole.Over 10-year period under study, class neoplasms was decreasing, while increasing. Adult reduced 12%, - 25%. It should be noted, rate (302.5 per 100,000) significantly (by 34%) lower than Russia (460.3), at same time, reduction over equal amounts 23-25%. Myocardial infarction serious characterized it has declining trend whole. increased 3 times, almost 5 annual increase during first year pandemic 88% 24% Russia. In Moscow, more half (66%) deaths belongs non-insulin-dependent diabetes mellitus, about 80%. Compared Russia's average, are 8%, but decline happens similar (11-12%).Despite impact COVID-19 pandemic, demonstrates slowdown growth Federation, which could have been positively affected prevention programs noncommunicable promotion healthy lifestyles.Введение. Ожирение считается одной из наиболее значимых проблем здравоохранения, представляет собой распространённое хроническое заболевание, приводящее к развитию тяжёлых сопутствующих патологий, сопровождающихся утратой лет жизни с поправкой на инвалидность, и высокой смертности. также является одним ведущих факторов риска возникновения ряда неинфекционных заболеваний: болезней системы кровообращения (БСК), эндокринной злокачественных новообразований.Цель исследования оценка динамики смертности взрослого населения от причин, ассоциированных ожирением, в Москве сравнении Российской Федерацией за 2011-2020 гг.Материалы методы. Использовались данные пакета анализа программы внутреннего использования «Фактографическая автоматизированная информационно-поисковая система» по стандартизированным показателям г. Москвы Федерации.Результаты. За исследуемый 10-летний период отмечается снижение классу БСК онкологических заболеваний, то же время рост болезням системы. Смертность сократилась России Стоит отметить, что уровень (302,5 100 тыс. населения) значительно (на ниже, чем (460,3), при этом темпы снижения равные составляют Наиболее серьёзным ассоциированным ожирением заболеванием, характеризующимся летальностью БСК, инфаркт миокарда, имеющий динамику целом. выросла раза, а почти раз, годовой прирост первого года пандемии составил 88%, 24%. В сахарному диабету 2-го типа структуре причин смерти принадлежит более половины (66%), со среднероссийскими показателями уровни классе новообразований ниже но происходит сходными темпами (11-12%).Заключение. Несмотря влияние COVID-19, темпа прироста показателей заболеваний Федерации, которые могли оказать позитивное воздействие профилактике формированию здорового образа жизни.

Язык: Русский

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