Published: Jan. 1, 2015

The article describes the etiologic role of various factors such as chronic rheumatic heart disease, bacterial endocarditis, aortic valve stenosis, hypertension, coronary heart disease, including acute myocardial infarction, degenerative disease of the valves, connective tissue diseases, chest trauma, sys-temic lupus erythematosus, con-genital heart disease which leading to the mitral valve chords rupture, gives the current classification of the nosology and also features of manifestation and clinical course. The authors also described a clinical case of mitral valve posterior leaflet chord rupture in the patient with hypertension, ischemic heart disease and chronic obstructive pulmonary disease, which reflects all the stages of …

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Published: Jan. 1, 2016

In the conditions of introduction of the proper practice of production of medicinal facilities on pharmaceutical enterprises in Ukraine, it is necessary to develop effective measures of projects management for creation of favourable conditions for modernisation of pharmaceutical production, innovative management and management of development projects. The optimization of pharmaceutical production of injection preparations, modernisation of the pharmaceutical industries, is being implemented in accordance with the standards of GM. Risks-control of pharmaceutical production of hi-tech parenteral preparations on a new level is carried out at the following stages: preparation of raw material, preparation of facilities and equipment; the process of …

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Published: Dec. 14, 2017

Simultaneous interpreting (SI) is difficult to reduce to an efficient and ecologically valid experimental paradigm allowing the measurement of working memory (WM) and attention — key components of all cognitive models of SI. These models could be validated and further refined in light of electrophysiological evidence. Here we propose a novel method for estimating WM load and report the results of our electroencephalographic study that lend support to the prediction of the Efforts Model of SI (Gile, 1988). In particular, this model predicts that increased WM load impairs the processing of auditory stimuli. Consistent with the model, the P1 and …

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Published: April 1, 2016

In the current study, two standardized English-language assessments, the AWMA by T.P. Alloway (2007) and the WMRS (Alloway, Gathercole, & Kirkwood, 2008), were translated into Russian. The translated version of the AWMA was undertaken by 51 adults and 73 primary school children, and the translated version of the WMRS was completed by the teachers who worked with those children. The WMRS is a questionnaire list for teachers with 20 items which describe possible behavior manifestations of poor working memory in the classroom. The AWMA is a computer test battery with 12 subtests which aim to assess verbal short-term memory, verbal …

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Published: May 31, 2014

The mesolimbic dopamine system is believed to be a key component in the processing of rewarding information by the brain, although the precise nature of dopamine release remains unknown. Avoidance conditioning combines reward (positive) and aversion (negative) phenomena. Here the activity of 60 neurons in the ventral tegmental area (VTA) was studied in freely moving rabbits during the acquisition and performance of an active avoidance. A total of 48 % of the recorded neurons responded to the conditioned stimulus (CS). A significant predominance of excitatory responses to the (CS) was demonstrated. Two main patterns of cell responses to the CS …

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Published: Sept. 26, 2014

One of the urgent problems in cognitive studies and in neurobiology as a whole is to delineate the impact of genetic factors in the variability of animal cognitive abilities. The concept of animal cognition is frequently used in a broad sense to include all phenomena with behavioral manifestations of neural plasticity. The variable phenomena related to animal cognition could be subdivided into two main categories, although only the first of them will be analyzed in this paper. The first category is represented by “basal” cognitive abilities, which embrace spatial cognitive behavior and elementary reasoning (simple logic task solutions). The second …

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Published: Sept. 18, 2014

The influence of expectation on inattentional blindness (IB) was investigated using a lexical-based IB task. In two experiments, 235 participants performed word compilations from briefly presented letters and combinations of letters with an unexpected syllable appearing in one of the trials. In Experiment 1, we varied the frequency and grammatical form ofthe presented words, evaluating the role of “general” and “contextual” expectations. The results showed the effect of frequency but not of the grammatical form of the words. Experiment 2 controlled for the role of the state of completion of the word compilation in generating “contextual” expectations. We varied two …

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Published: Jan. 1, 2014

In the second year of life, infants are actively interested in objects used by adults, despite the number of experienced difficulties in achieving their goals while handling these objects. What causes the child attempt to handle an object for a designated purpose while watching the adult? One of the evident explanations concerns the effectiveness of the adults behavior and the child’s desire to achieve the same result. However, multiple studies have shown that a child is guided not exclusively by the hoped-for result, but also by the adults intention. In our study, we verified the reason guiding a child’s choice …

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Published: Jan. 1, 2014

Almost 50 years ago, Reber described implicit learning as the unintentional and unconscious processing of regularities in the environment. Since then, psychologists have actively investigated this phenomenon. However, there is currently no unambiguous description of the mechanisms of implicit learning. Moreover, the descriptions of implicit learning properties vary depending on the approach to the phenomenon. The main theoretical accounts developed in the last decades are presented in this work. Four types of theories are identified, which differ in how they answer two main questions: 1) How explicit is the knowledge acquired during implicit learning?; and 2) How automatically is it …

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Published: Jan. 1, 2014

This paper describes the possible methodological techniques of evaluation of the problem solving process as the main task by a secondary probe task. We propose a method of estimation of the microdynamics of thought processes via changes in the dynamics of working memory load in problem solving by a probe monitor. The results of assessment of the dynamics of working memory load in insight and algorithmized problem solving via a two-alternative choice task are shown. There are significant differences between the dynamics of working memory load in insight and algorithmized problem solving in the last stages, which confirm the hypothesis …

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