Pain Self-Management Strategies for Hidradenitis Suppurativa Patients: An In-Person Survey Study DOI
Christina Huang, Matthew Keller, Sherry Yang

et al.

Journal of Cutaneous Medicine and Surgery, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 30, 2024

Background: Pain is an undermanaged symptom of hidradenitis suppurativa (HS). Relatively few studies have investigated at-home pain management measures HS patients use, the efficacy these measures, and how they may correlate with disease severity. Objectives: The objective this study to survey strategies used by evaluate their efficacy. Methods: We conducted a on from April 2023 2024 at Hidradenitis Suppurativa Clinic Thomas Jefferson University Hospital (Philadelphia, PA). measured usage certain options in past year for asked rank relief each measure Likert scale. also recorded clinically determined Hurley stage severity correlations between methods used/efficacy. Results: Surveyed (n = 63) indicated preference over-the-counter (OTC) topical measures. For higher stages, rates cannabis or prescription were higher. Patients III reported significantly greater opioid non-opioid medications when compared oral OTC medications; however, degree was considerably less than that obtained milder disease. Conclusion: can be challenging patients, especially among those Of note, altered pathways could contribute reduced effect more severe stages.

Language: Английский

An overview of S100 proteins and their functions in skin homeostasis, interface dermatitis conditions and other skin pathologies DOI Open Access
Warda Abdi,

Andrew Romasco,

Dany Alkurdi

et al.

Experimental Dermatology, Journal Year: 2024, Volume and Issue: 33(8)

Published: Aug. 1, 2024

Abstract S100 proteins comprise a family of structurally related that are calcium‐sensitive. have been found to play various roles in regulation cell apoptosis, proliferation and differentiation, migration invasion, energy metabolism, calcium homeostasis, protein phosphorylation, anti‐microbial activity inflammation variety types. While the specific function many remains unknown, some serve as disease biomarkers well possible therapeutic targets skin diseases. Interface dermatitis (ID) is histopathological term covers different conditions including cutaneous lupus erythematosus, lichen planus, dermatomyositis. These pathologies share similar histological features, which include basal vacuolization lymphocytic infiltration at dermal‐epidermal junction. In this review, we summarize how contributes both homeostatic inflammatory processes skin. We also highlight role neuronal signalling, describing might contribute neuroimmune interactions ID other pathologies. Last, discuss what known about potential treatment

Language: Английский

Citations

4
Erectile dysfunction in dermatology and venereology: From aetiopathogenic mechanisms to practical considerations for dermato‐venereologists DOI Creative Commons
Andrei Tanasov, George‐Sorin Ţiplica

Journal of the European Academy of Dermatology and Venereology, Journal Year: 2025, Volume and Issue: unknown

Published: March 8, 2025

Erectile dysfunction (ED) is an often undiagnosed but significantly prevalent condition among male dermato-venereological patients, characterized by a complex pathophysiology and substantial impact on quality of life. This review aimed to synthesize recent literature the increased risk ED in skin diseases, underlying pathogenic mechanisms-including vasculogenic, endocrine, neurogenic, psychogenic immunologic pathways-as well as dermatologist's role managing patients' sexual health. Inflammatory conditions (e.g. psoriasis, atopic dermatitis, lichen simplex chronicus chronic hand eczema), infections (viral, bacterial fungal, including sexually transmitted infections), autoimmune scleroderma pemphigus) disorders apocrine eccrine glands (such hidradenitis suppurativa) have all been linked ED. The multi-systemic nature many dermatologic diseases has become increasingly evident due their associations with cardiovascular metabolic comorbidities (atherosclerosis, hypertension, syndrome vitamin D deficiency), central peripheral neuropathies, endocrine (hypogonadism diabetes mellitus) or genito-urinary sequelae infections, while further highlights major mental health burden conditions. Dermatologists are unique position evaluate function factors, investigate potential causes through accessible routine tests, prescribe impotence medication, consider erectile overall treatment choice provide integrative lifestyle recommendations. Addressing practice offers significant benefits for both patients healthcare systems, improving compliance, reducing logistical challenges optimizing financial outcomes.

Language: Английский

Citations

0
Australasian hidradenitis suppurativa management guidelines DOI Creative Commons
John W. Frew, Annika Smith, Pablo Fernández‐Peñas

et al.

Australasian Journal of Dermatology, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 22, 2024

Abstract Hidradenitis Suppurativa is a burdensome inflammatory skin disease with significant quality of life impact. These management guidelines were developed to direct appropriate clinical in the Australasian context. A systematic review was used for basis consensus guidelines. Thirteen experts involved modified Delphi process develop and treatment algorithms. Overall strategies include severity assessment comorbidities, multimodal therapy systemic local treatments, evidence‐based progression along therapeutic ladder event inadequate response. Sequential monotherapy antibiotics and/or single agent discouraged aggressive moderate severe capture window opportunity highly emphasised. Specific considerations setting pregnancy breastfeeding are also addressed. Overall, complex nature HS requires response medical, physical surgical therapies achieve best patient outcomes.

Language: Английский

Citations

2
Pain management in hidradenitis suppurativa DOI

Vedaja Surapaneni,

Miloš Milosavljević, Lauren A.V. Orenstein

et al.

Journal of the American Academy of Dermatology, Journal Year: 2024, Volume and Issue: 91(6), P. S52 - S63

Published: Dec. 1, 2024

Language: Английский

Citations

1
Elucidation of Pain Mechanisms in Hidradenitis Suppurativa DOI
Sarah K. Whitley

JAMA Dermatology, Journal Year: 2023, Volume and Issue: 159(10), P. 1047 - 1047

Published: Sept. 13, 2023

Our website uses cookies to enhance your experience. By continuing use our site, or clicking "Continue," you are agreeing Cookie Policy | Continue JAMA Dermatology HomeNew OnlineCurrent IssueFor Authors Podcast Journals Network Open Cardiology Health Forum Internal Medicine Neurology Oncology Ophthalmology Otolaryngology–Head & Neck Surgery Pediatrics Psychiatry Archives of (1919-1959) JN Learning / CMESubscribeJobsInstitutions LibrariansReprints Permissions Terms Use Privacy Accessibility Statement 2023 American Medical Association. All Rights Reserved Search Archive Input Term Sign In Individual inCreate an Account Access through institution Purchase Options: Buy this article Rent Subscribe the journal

Language: Английский

Citations

1
Pain Self-Management Strategies for Hidradenitis Suppurativa Patients: An In-Person Survey Study DOI
Christina Huang, Matthew Keller, Sherry Yang

et al.

Journal of Cutaneous Medicine and Surgery, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 30, 2024

Background: Pain is an undermanaged symptom of hidradenitis suppurativa (HS). Relatively few studies have investigated at-home pain management measures HS patients use, the efficacy these measures, and how they may correlate with disease severity. Objectives: The objective this study to survey strategies used by evaluate their efficacy. Methods: We conducted a on from April 2023 2024 at Hidradenitis Suppurativa Clinic Thomas Jefferson University Hospital (Philadelphia, PA). measured usage certain options in past year for asked rank relief each measure Likert scale. also recorded clinically determined Hurley stage severity correlations between methods used/efficacy. Results: Surveyed (n = 63) indicated preference over-the-counter (OTC) topical measures. For higher stages, rates cannabis or prescription were higher. Patients III reported significantly greater opioid non-opioid medications when compared oral OTC medications; however, degree was considerably less than that obtained milder disease. Conclusion: can be challenging patients, especially among those Of note, altered pathways could contribute reduced effect more severe stages.

Language: Английский

Citations

0