Sexual Orientation and Lifetime Prevalence of Skin Cancer Across Racial and Ethnic Groups DOI
Katelyn J. Rypka,

Zachary Wendland,

Maritza V. Steele

et al.

JAMA Dermatology, Journal Year: 2024, Volume and Issue: 160(9), P. 977 - 977

Published: July 17, 2024

Importance Sexual minority (SM) persons have been found to differential rates of skin cancer, but limited data exist on differences across racial and ethnic groups by individual sexual identities. Objective To examine orientation in the lifetime prevalence cancer among US adult females males identity. Design, Setting, Participants This cross-sectional study used from Behavioral Risk Factor Surveillance System January 1, 2014, December 31, 2021, for adults general population. Data were analyzed 2023, March 2024. Main Outcomes Measures Self-reported orientation. Age-adjusted adjusted odds ratios (AORs) compared heterosexual SM analyses stratified race. Results Of 1 512 400 participants studied, 805 161 (53.2%) females; 38 933 (2.6%), 638 651 (42.2%), males; 29 655 (2.0%), males. A total 6.6% Hispanic; 3.4%, non-Hispanic Asian, Pacific Islander, or Hawaiian; 7.5%, Black; 78.2%, White; 4.3%, other race ethnicity. Mean (SE) age was 48.5 (0.03) years (incomplete respondents ≥80 years). The overall higher with (7.4% vs 6.8%; AOR, 1.16; 95% CI, 1.02-1.33), including specifically Hispanic (4.0% 1.6%; 3.81; 1.96-7.41) Black (1.0% 0.5%; 2.18; 1.13-4.19) Lifetime lower White (7.8% 8.5%; 0.86; 0.76-0.97) (2.1% 1.8%; 2.46; 1.28-4.70) (1.8% 2.33; 1.01-5.54) Conclusions Relevance In this adults, differed identity both Both had their counterparts. Further research addressing factors contributing these is needed inform screening guidelines public health interventions focused diverse, heterogeneous populations.

Language: Английский

Performance evaluation of E-VGG19 model: Enhancing real-time skin cancer detection and classification DOI Creative Commons
Irfan Ali Kandhro,

Selvakumar Manickam,

Kanwal Fatima

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(10), P. e31488 - e31488

Published: May 1, 2024

Skin cancer is a pervasive and potentially life-threatening disease. Early detection plays crucial role in improving patient outcomes. Machine learning (ML) techniques, particularly when combined with pre-trained deep models, have shown promise enhancing the accuracy of skin detection. In this paper, we enhanced VGG19 model max pooling dense layer for prediction cancer. Moreover, also explored models such as Visual Geometry Group 19 (VGG19), Residual Network 152 version 2 (ResNet152v2), Inception-Residual (InceptionResNetV2), Dense Convolutional 201 (DenseNet201), 50 (ResNet50), Inception 3 (InceptionV3), For training, lesions dataset used malignant benign cases. The extract features divide into two categories: benign. are then fed machine methods, including Linear Support Vector (SVM), k-Nearest Neighbors (KNN), Decision Tree (DT), Logistic Regression (LR) our results demonstrate that combining E-VGG19 traditional classifiers significantly improves overall classification classification. compared performance baseline metrics (recall, F1 score, precision, sensitivity, accuracy). experiment provide valuable insights effectiveness various accurate efficient This research contributes to ongoing efforts create automated technologies detecting can help healthcare professionals individuals identify potential cases at an early stage, ultimately leading more timely effective treatments.

Language: Английский

Citations

15
Efficacy and Safety of Rechallenge with BRAF/MEK Inhibitors in Advanced Melanoma Patients: A Systematic Review and Meta-Analysis DOI Open Access
Jonathan N. Priantti, Maysa Vilbert, Thiago Madeira

et al.

Cancers, Journal Year: 2023, Volume and Issue: 15(15), P. 3754 - 3754

Published: July 25, 2023

This systematic review and meta-analysis aims to evaluate the efficacy safety of rechallenging advanced melanoma patients with BRAFi/MEKi. Seven studies, accounting for 400 patients, were included. Most received immunotherapy before rechallenge, 79% underwent rechallenge combination We found a median progression-free survival 5 months overall 9.8 months. The one-year rate was 42.63%. Regarding response, ORR 34% DCR 65%. There no new or unexpected concerns. Rechallenge BRAFi/MEKi can improve outcomes in refractory disease. These findings have significant implications clinical practice, particularly setting progressive disease later lines limited treatment options.

Language: Английский

Citations

14
Acral lentiginous melanoma incidence by sex, race, ethnicity, and stage in the United States, 2010–2019 DOI
Dawn M. Holman, Jessica King, Arica White

et al.

Preventive Medicine, Journal Year: 2023, Volume and Issue: 175, P. 107692 - 107692

Published: Sept. 1, 2023

Language: Английский

Citations

7
Sexual Orientation and Lifetime Prevalence of Skin Cancer Across Racial and Ethnic Groups DOI
Katelyn J. Rypka,

Zachary Wendland,

Maritza V. Steele

et al.

JAMA Dermatology, Journal Year: 2024, Volume and Issue: 160(9), P. 977 - 977

Published: July 17, 2024

Importance Sexual minority (SM) persons have been found to differential rates of skin cancer, but limited data exist on differences across racial and ethnic groups by individual sexual identities. Objective To examine orientation in the lifetime prevalence cancer among US adult females males identity. Design, Setting, Participants This cross-sectional study used from Behavioral Risk Factor Surveillance System January 1, 2014, December 31, 2021, for adults general population. Data were analyzed 2023, March 2024. Main Outcomes Measures Self-reported orientation. Age-adjusted adjusted odds ratios (AORs) compared heterosexual SM analyses stratified race. Results Of 1 512 400 participants studied, 805 161 (53.2%) females; 38 933 (2.6%), 638 651 (42.2%), males; 29 655 (2.0%), males. A total 6.6% Hispanic; 3.4%, non-Hispanic Asian, Pacific Islander, or Hawaiian; 7.5%, Black; 78.2%, White; 4.3%, other race ethnicity. Mean (SE) age was 48.5 (0.03) years (incomplete respondents ≥80 years). The overall higher with (7.4% vs 6.8%; AOR, 1.16; 95% CI, 1.02-1.33), including specifically Hispanic (4.0% 1.6%; 3.81; 1.96-7.41) Black (1.0% 0.5%; 2.18; 1.13-4.19) Lifetime lower White (7.8% 8.5%; 0.86; 0.76-0.97) (2.1% 1.8%; 2.46; 1.28-4.70) (1.8% 2.33; 1.01-5.54) Conclusions Relevance In this adults, differed identity both Both had their counterparts. Further research addressing factors contributing these is needed inform screening guidelines public health interventions focused diverse, heterogeneous populations.

Language: Английский

Citations

0