Pharmacoequity measurement framework: A tool to reduce health disparities DOI
Pranav Patel, Utibe R. Essien,

Laura E. Happe

et al.

Journal of Managed Care & Specialty Pharmacy, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 11

Published: Dec. 20, 2024

is a health system and policy goal of ensuring equitable access to high-quality medications for all individuals, regardless factors such as race, ethnicity, socioeconomic status, or resource availability reduce disparities. Although measurement frameworks have been widely used in equity contexts, focused framework pharmacoequity remains critical gap. In this article, we introduce novel anchored the patient medication-use journey. The includes following domains: (1) care services, (2) prescription generation, (3) primary medication nonadherence, (4) secondary (5) monitoring. For each domain, provide examples outcome measures potential data sources that can be evaluation. We also outline an implementation workflow population stakeholders use across various settings (eg, systems, plans). provides structured approach identify existing gaps path toward achieving lay foundation targeted interventions. Additionally, it enables ongoing monitoring progress while identifying interventions are effective, scalable, sustainable.

Language: Английский

2024 ACC Expert Consensus Decision Pathway for Treatment of Heart Failure With Reduced Ejection Fraction DOI
Thomas M. Maddox, James L. Januzzi, Larry A. Allen

et al.

Journal of the American College of Cardiology, Journal Year: 2024, Volume and Issue: 83(15), P. 1444 - 1488

Published: March 8, 2024

Language: Английский

Citations

71

Applications of SGLT2 inhibitors beyond glycaemic control DOI
Daniel V. O’Hara, Carolyn S.P. Lam, John J.V. McMurray

et al.

Nature Reviews Nephrology, Journal Year: 2024, Volume and Issue: 20(8), P. 513 - 529

Published: April 26, 2024

Language: Английский

Citations

26

Role of lifestyle and glucagon‐like peptide‐1 receptor agonists for weight loss in obesity, type 2 diabetes and steatotic liver diseases DOI Creative Commons
Anna Giannakogeorgou, Michael Roden

Alimentary Pharmacology & Therapeutics, Journal Year: 2024, Volume and Issue: 59(S1)

Published: May 30, 2024

Summary Background The current obesity pandemic has given rise to associated comorbidities and complications, including type 2 diabetes metabolic dysfunction‐associated steatotic liver disease (MASLD). During the last decade, certain glucagon‐like peptide 1 receptor agonists (GLP‐1RA), originally developed as antihyperglycemic drugs, also demonstrated efficacy for weight loss. Aims To review shared pathophysiologic features of common diseases compare therapeutic strategies reduce body related complications. Methods We performed an extensive literature research describe effects lifestyle modification, first‐generation anti‐obesity GLP‐1RA on loss in humans with obesity, MASLD. Results Until recently, treatment been limited which offer moderate degree sustainability few approved drugs are either short term use or forms obesity. Some significantly decrease caloric intake weight. Liraglutide semaglutide have therefore treating people They lead a reduction hepatic fat content inflammation biopsy‐confirmed Possible limitations comprise adverse effects, adherence persistence. Conclusion Certain superior modification inducing markedly changed portfolio additional beneficial disease.

Language: Английский

Citations

12

Association of GLP-1 Receptor Agonists with Chronic Obstructive Pulmonary Disease Exacerbations among Patients with Type 2 Diabetes DOI
Dinah Foer, Zachary H. Strasser, Jing Cui

et al.

American Journal of Respiratory and Critical Care Medicine, Journal Year: 2023, Volume and Issue: 208(10), P. 1088 - 1100

Published: Aug. 30, 2023

Patients with chronic obstructive pulmonary disease (COPD) and type 2 diabetes (T2D) have worse clinical outcomes compared patients without metabolic dysregulation. GLP-1 (glucagon-like peptide 1) receptor agonists (GLP-1RAs) reduce asthma exacerbation risk improve FVC in COPD.

Language: Английский

Citations

22

1. Improving Care and Promoting Health in Populations: Standards of Care in Diabetes—2025 DOI
Nuha A. ElSayed, Rozalina G. McCoy, Grazia Aleppo

et al.

Diabetes Care, Journal Year: 2024, Volume and Issue: 48(Supplement_1), P. S14 - S26

Published: Dec. 9, 2024

The American Diabetes Association (ADA) “Standards of Care in Diabetes” includes the ADA’s current clinical practice recommendations and is intended to provide components diabetes care, general treatment goals guidelines, tools evaluate quality care. Members ADA Professional Practice Committee, an interprofessional expert committee, are responsible for updating Standards annually, or more frequently as warranted. For a detailed description standards, statements, reports, well evidence-grading system full list Committee members, please refer Introduction Methodology. Readers who wish comment on invited do so at professional.diabetes.org/SOC.

Language: Английский

Citations

7

Neighborhood-Level Socioeconomic Status and Prescription Fill Patterns Among Patients With Heart Failure DOI Creative Commons
Amrita Mukhopadhyay, Saul Blecker, Xiyue Li

et al.

JAMA Network Open, Journal Year: 2023, Volume and Issue: 6(12), P. e2347519 - e2347519

Published: Dec. 14, 2023

Importance Medication nonadherence is common among patients with heart failure reduced ejection fraction (HFrEF) and can lead to increased hospitalization mortality. Patients living in socioeconomically disadvantaged areas may be at greater risk for medication due barriers such as lower access transportation or pharmacies. Objective To examine the association between neighborhood-level socioeconomic status (nSES) HFrEF assess mediating roles of transportation, walkability, pharmacy density. Design, Setting, Participants This retrospective cohort study was conducted June 30, 2020, December 31, 2021, a large health system based primarily New York City surrounding areas. Adult diagnosis HF, EF on echocardiogram, prescription least 1 guideline-directed medical therapy (GDMT) were included. Exposure Patient addresses geocoded, nSES calculated using Agency Healthcare Research Quality SES index, which combines census-tract level measures poverty, rent burden, unemployment, crowding, home value, education, higher values indicating nSES. Main Outcomes Measures obtained through linkage record data fill defined proportion days covered (PDC) less than 80% over 6 months, averaged across GDMT medications. Results Among 6247 patients, mean (SD) age 73 (14) years, majority male (4340 [69.5%]). There 1011 (16.2%) Black participants, 735 (11.8%) Hispanic/Latinx 3929 (62.9%) White participants. had rates nonadherence, ranging from 51.7% lowest quartile (731 1086 participants) 40.0% highest (563 ( P < .001). In adjusted analysis, 2 quartiles significantly odds when compared (quartile 1: ratio [OR], 1.57 [95% CI, 1.35-1.83]; 2: OR, 1.35 1.16-1.56]). No mediation by density found, but small amount neighborhood walkability observed. Conclusions Relevance this HFrEF, area associated nonadherence. These findings highlight importance considering disparities developing approaches improve adherence.

Language: Английский

Citations

15

Underuse of GLP-1 receptor agonists in the management of type 2 diabetes despite a favorable benefit-safety profile DOI
André Scheen

Expert Opinion on Drug Safety, Journal Year: 2024, Volume and Issue: 23(7), P. 797 - 810

Published: May 13, 2024

Patients with type 2 diabetes (T2DM) are at high risk of atherosclerotic cardiovascular disease (ASCVD) and death. Cardiovascular protection is a key objective in T2DM.

Language: Английский

Citations

4

Pharmacoequity measurement framework: A tool to reduce health disparities DOI
Pranav Patel, Utibe R. Essien,

Laura E. Happe

et al.

Journal of Managed Care & Specialty Pharmacy, Journal Year: 2025, Volume and Issue: 31(2), P. 214 - 224

Published: Feb. 1, 2025

Pharmacoequity is a health system and policy goal of ensuring equitable access to high-quality medications for all individuals, regardless factors such as race, ethnicity, socioeconomic status, or resource availability reduce disparities. Although measurement frameworks have been widely used in equity contexts, focused framework pharmacoequity remains critical gap. In this article, we introduce novel anchored the patient medication-use journey. The includes following domains: (1) care services, (2) prescription generation, (3) primary medication nonadherence, (4) secondary (5) monitoring. For each domain, provide examples outcome measures potential data sources that can be evaluation. We also outline an implementation workflow population stakeholders use across various settings (eg, systems, plans). provides structured approach identify existing gaps path toward achieving lay foundation targeted interventions. Additionally, it enables ongoing monitoring progress while identifying interventions are effective, scalable, sustainable.

Language: Английский

Citations

0

Trends in the use of advance care planning and cognitive assessment and care planning service visits: moving toward a palliative‐informed approach for ambulatory care of community‐dwelling persons with dementia and their caregivers DOI Creative Commons
Jennifer B. Seaman, Yurun Cai, Dianxu Ren

et al.

Alzheimer s & Dementia, Journal Year: 2025, Volume and Issue: 21(4)

Published: April 1, 2025

Abstract INTRODUCTION Both the advance care planning (ACP) visit and cognitive assessment service (CAACPS) offer palliative‐oriented for persons with Alzheimer's disease related dementias (ADRD); however, rate of ACP visits remains low, little has been reported regarding CAACPS visits. Furthermore, few reports describe use either among Medicare Advantage (MA) beneficiaries. This study describes provision to community‐dwelling older adult MA beneficiaries ADRD. METHODS Using deidentified Optum Clinformatics Data Mart claims data, we evaluated ambulatory ADRD years 2018 2019. RESULTS For 2019, 3.5% 5.4% received visits, 0.4% 0.5% similar elsewhere. DISCUSSION Few or delivery CAACPs is that non‐MA Highlights Most dementia are disproportionately disadvantaged. Access palliative limited dementia. may address this gap. Our findings show very low.

Language: Английский

Citations

0

Health Care Expenditure among US Adults with Heart Failure with and without Diabetes DOI
Chintal H. Shah, Gregg C. Fonarow, Justin B. Echouffo‐Tcheugui

et al.

The American Journal of Cardiology, Journal Year: 2024, Volume and Issue: 228, P. 10 - 15

Published: July 25, 2024

Language: Английский

Citations

3