Temporal, spatial and demographic distributions characteristics of COVID-19 symptom clusters from chinese medicine perspective: a systematic cross-sectional study in China from 2019 to 2023

Chinese Medicine, Journal Year: 2024, Volume and Issue: 19(1)

Published: Dec. 18, 2024

Language: Английский

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Epidemiology and SARS-CoV-2 Infection Patterns among Youth Followed at a Large Los Angeles Health Network during 2020–2022: Clinical Presentation, Prevalent Strains, and Correlates of Disease Severity

Vaccines, Journal Year: 2023, Volume and Issue: 11(6), P. 1024 - 1024

Published: May 25, 2023

Background: Outcomes of SARS CoV-2 infection in infants, children and young adults are reported less frequently than older populations. The evolution SARS-CoV-2 cases LA County youths followed at a large health network southern California over two years was evaluated. Methods: A prospective cohort study patients aged 0–24 diagnosed with COVID-19 conducted. Demographics, age distribution, disease severity, circulating variants concern (VOCs), immunization rates were compared between first second pandemic years. Logistic regression estimated odds ratios (OR) 95% confidence intervals (CI) factors associated severe/critical COVID-19. Results: In total, 61,208 tested for by polymerase chain reaction (PCR); 5263 positive (8.6%) available data identified March 2020 2022. Year 1, 5.8% (1622/28,088) positive, to 11% (3641/33,120) 2 (p < 0.001). Most had mild/asymptomatic illness positivity >12% across all groups the half 2, when Omicron prevailed. Pulmonary higher risk severe both (OR: 2.4, CI: 1.4–4.3, p = 0.002, 1; OR: 11.3, 4.3–29.6, Receipt least one vaccine dose protective against 0.3, 0.11–0.80, 0.05). Conclusions: Despite different VOCs test most asymptomatic/mild disease. Underlying pulmonary conditions increased COVID-19, while vaccination highly youths.

Language: Английский

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Associations between COVID-19 Vaccination Status and Self-Reported SARS-CoV-2 Infection among 8538 Children Aged 3–17 Years during a Massive COVID-19 Outbreak after China Changed Its Zero-COVID-19 Policy: A Cross-Sectional Survey

Vaccines, Journal Year: 2023, Volume and Issue: 11(9), P. 1401 - 1401

Published: Aug. 22, 2023

This study aimed to investigate the associations between COVID-19 vaccination status and self-reported SARS-CoV-2 infection among children adolescents aged 3–17 years during a massive outbreak after China changed its zero COVID policy. A cross-sectional online survey was conducted 1 9 March 2023. Participants were parents of studying in kindergartens, primary schools, or secondary schools Shenzhen. Convenient sampling used. All Longhua District Shenzhen invited attending schools. Interested completed an survey. Multivariate logistic regression fitted. Among 8538 participants, 40.9% that their had 7 December 2022, where 92.9% them received two doses vaccines, 74.6% second dose for more than six months. In multivariate analysis, who no three months lower rate compared unvaccinated (<1 month: AOR: 0.17, 95% CI: 0.07, 0.44; 1–3 months: 0.54, 0.41, 0.75). The duration protection conferred by series relatively short children. booster should be considered

Language: Английский

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Vaccine Effectiveness against SARS-CoV-2 Infection during the Circulation of Alpha, Delta, or Omicron Variants: A Retrospective Cohort Study in a Tertiary Hospital in Serbia

Vaccines, Journal Year: 2024, Volume and Issue: 12(2), P. 211 - 211

Published: Feb. 18, 2024

The COVID-19 pandemic prompted rapid vaccine development and deployment worldwide. Despite widespread vaccination efforts, understanding the effectiveness of vaccines in hospitalized patients remains a critical concern. This retrospective cohort study, conducted at tertiary healthcare centre Serbia, tracked during different waves variants—Alpha, Delta, Omicron. Data collection included demographics, comorbidities, symptoms, status. Among 3593 patients, those with prior exposure to cases or hospital treatment showed higher positivity rates. Symptom prevalence varied across waves, coughs persisting. Patients without chronic diseases were more frequent among testing negative. Vaccine varied, Sinopharm demonstrating 45.6% initially Pfizer-BioNTech showing an up 74.8% within 0–84 days after second dose. Mixed-dose strategies, notably as primary dose followed by booster, suggested increased protection. substantial availability, significant portion remained unvaccinated. study underscores dynamic nature advocates for booster strategies address evolving challenges combating COVID-19, particularly patients.

Language: Английский

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Respiratory syncytial virus infection in children during SARS-CoV-2 pandemic at a referral center in Rio de Janeiro, Brazil

Jornal Brasileiro de Pneumologia, Journal Year: 2024, Volume and Issue: unknown, P. e20240072 - e20240072

Published: July 9, 2024

Objective: In order to study the scenario of respiratory infections in pediatrics after emergence SARS-CoV-2 Brazil, this aimed compare characteristics children admitted for SARS or upper airway infection caused by either RSV SARS-CoV-2. Methods: This was a cross-sectional involving up 48 months age tertiary pediatric hospital with diagnosis between April 2020 and 2021. Respiratory secretion samples were collected 2-5 days hospitalization, antigen/PCR tests viral etiologies performed. analysis, patients laboratorial and/or selected, their clinical epidemiological compared using logistic regression. Results: Our sample initially comprised 369 participants. confirmed 55 (15%) 59 (16%), respectively. Mean 12 (0-48 months), 47 female. The following significantly more frequent when those COVID-19: younger (OR = 0.94; 95% CI: 0.90-0.98); lower frequency fever 0.18; 0.05-0.66); symptoms: cough 7.36; 1.04-52.25); tachypnea 6.06; 1.31-28.0). Conclusions: Children RSV-related younger, had at admission, but higher signs systemic inflammation hospitalized COVID-19 during first year pandemic.

Language: Английский

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