Aligning Medications With What Matters Most: Conversations Between Pharmacists, People With Dementia, and Care Partners
Journal of the American Geriatrics Society,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 3, 2025
Successful
deprescribing
for
people
with
dementia
(PWD)
depends
on
communication
about
medication-related
priorities
between
PWD,
care
partners
and
clinicians.
The
objective
of
this
study
was
to
gain
in-depth
knowledge
how
elicitation
PWD
partner
during
a
intervention
shaped
discussions
pharmacists
medications.
Qualitative
analysis
audio-recorded
interactions
patient-care
dyads
in
pilot
pharmacist-led
primary
care.
Patients
≥
65
years
taking
7
medications
were
recruited
from
an
integrated
delivery
system
Colorado
community-based
medical
practice
Maryland.
content
used
analyze
82
transcripts
encounters
55
dyads.
mean
(SD)
age
81
(8.1)
years;
45%
women,
33%
Black,
15%
Hispanic.
took
average
13
(±5.3)
at
baseline.
Care
66
(13)
most
spouses/partners
the
PWD.
Content
identified
five
themes:
(1)
Reducing
treatment
burden;
(2)
Alleviating
burdensome
symptoms;
(3)
Maintaining
cognition
function;
(4)
Discussion
tradeoffs;
(5)
Challenges
deprescribing.
After
eliciting
patient
priorities,
recommended
both
prescribing.
Findings
secondary
suggest
can
support
goal-concordant
These
results
inform
development
interventions
optimize
population.
Language: Английский
Multicomponent intervention to tailor prescriptions to patients with dementia in an intermediate care hospital: pre-post quasi experimental study
BMC Geriatrics,
Journal Year:
2025,
Volume and Issue:
25(1)
Published: Feb. 27, 2025
In
persons
with
dementia,
polypharmacy
may
be
discordant
the
goals
of
care.
It
is
necessary
to
design
interventions
that
align
treatment
regimens
patient's
situation,
prognosis
and
preferences.
The
objectives
this
study
conducted
at
an
intermediate
care
were
to:
i)
identify
inappropriate
prescribing
per
main
goal;
ii)
compare
pharmacotherapy
data
pre
post
a
medication
review
based
on
degree
cognitive
impairment;
iii)
assess
implementation
proposed
recommendations
three
months
after
discharge.
Pre-post
quasi-experimental
study.
Patients
dementia
discharged
from
hospital
between
November
2021
April
2022.
Demographic,
clinical
evaluated
admission.
Medication
reviews
interviews
caregivers
pharmacologic
therapies
overall
At
discharge,
information
was
shared
primary
team
in
discharge
summary.
Follow
up
evaluate
during
performed
months.
Of
97
patients
included,
94.8%
had
least
one
inappropriately
prescribed
medication.
mean
number
chronic
medications
taken
patient
decreased
by
29.6%,
8.05(SD
3.5)
5.67(SD
2.7)
(p
<
0.001);
anticholinergic
burden
18.6%,
1.59(SD
1.0)
1.29(SD
0.9)
therapeutic
complexity
28.4%,
29.23(SD
13.8)
20.94(SD
11.3)
0.001).
3
90.0%.
Admission
provides
ideal
setting
for
multicomponent
intervention,
tailoring
prescriptions
preferences,
improving
parameters
related
side
effects,
ensuring
are
maintained
over
medium
term.
Language: Английский
Potentially Inappropriate Prescriptionss in End-of-Life Cancer Patients in Home-Based Hospice Care
Journal of Pain and Symptom Management,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 1, 2025
Polypharmacy
and
inappropriate
prescribing
are
prevalent
among
end-of-life
cancer
patients,
potentially
compromising
symptom
management
quality
of
life.
Limited
data
available
on
medications
(PIMs)
omissions
(PPOs)
opioid
in
South
Korea,
particularly
home-based
hospice
care
settings.
This
study
aimed
to
evaluate
the
prevalence
PIMs
PPOs
advanced
patients
referred
identify
factors
associated
with
these
issues.
A
retrospective
observational
included
102
a
single
center's
between
November
2022
2023.
were
assessed
using
STOPPFrail
criteria,
while
defined
as
inadequate
for
moderate
severe
pain.
Logistic
regression
analysis
identified
PPOs.
observed
40.2%
higher
those
over
70
years
old
(48.7%)
multiple
comorbidities.
Statins
(25.5%)
antihypertensives
(29.4%)
most
common
PIMs.
Among
pain,
45.5%
experienced
due
prescriptions.
Older
age
(OR
3.90,
p
<
0.01)
comorbidities
20.90,
significantly
PIMs,
diabetes
was
linked
2.00,
=
0.01).
The
findings
highlight
critical
gaps
medication
patients.
Systematic
deprescribing
protocols
improved
strategies
address
stigma
hesitancy
essential
align
treatments
goals
enhance
patient
Language: Английский
Awareness, perspectives and practices of antibiotics deprescribing among physicians in Jordan: a cross-sectional study
Journal of Pharmaceutical Policy and Practice,
Journal Year:
2024,
Volume and Issue:
17(1)
Published: July 19, 2024
Background:
Antibiotics
have
significantly
reduced
mortality
and
improved
outcomes
across
various
medical
fields;
however,
the
rise
of
antibiotic
resistance
poses
a
major
challenge,
causing
millions
deaths
annually.
Deprescribing,
process
that
involves
discontinuing
unnecessary
antibiotics,
is
crucial
for
combating
this
threat.
This
study
was
designed
to
assess
knowledge,
perceptions,
practices
physicians
regarding
deprescribing
in
Jordan.
Language: Английский
Use of the Patient Portal to Discuss Medications Among People with Dementia and Their Care Partners
Journal of General Internal Medicine,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 1, 2024
Language: Английский
Considerations, barriers and enablers of deprescribing among healthcare professionals in Ogun State, Southwest, Nigeria: a cross-sectional survey
Sule A. Saka,
No information about this author
Tolulope Ruth Osineye
No information about this author
BMC Health Services Research,
Journal Year:
2024,
Volume and Issue:
24(1)
Published: May 24, 2024
Abstract
Background
Deprescribing
is
a
clinical
intervention
aimed
at
managing
polypharmacy
and
improving
older
adults’
health
outcomes.
However,
evidence
suggests
that
healthcare
professionals
(HCPs)
may
face
challenges
in
implementing
the
intervention.
This
study
to
explore
considerations,
barriers
enablers
of
deprescribing
among
HCPs
Southwest
Nigeria.
Methods
A
quantitative
cross-sectional
survey
was
carried
out
consecutively
sampled
including
physicians,
pharmacists
nurses
two
public
tertiary
hospitals
Ogun
State,
Southwest,
structured
43-item
self-administered
questionnaire
used
participants’
sociodemographics,
HCPs’
experience,
adults.
The
data
were
summarised
using
descriptive
statistics
frequency
percentage.
Kruskal–Wallis
test
determine
differences
perceptions
groups
on
Likert
scale.
p
-value
<
0.05
considered
significant.
Results
Overall,
453
copies
analysed.
Of
participants
204
(45.0%)
within
age
group
20–30
years;
173
(38.2%)
claimed
adults
occasionally
requested
their
medications.
majority
(417;
92.1%)
patients’
quality
life
be
very
important
deprescribing;
423
(93.4%)
opined
having
care
goal
known
members
HCP
team
an
enabler
for
while
308
(68.0%)
disagreed
or
strongly
lack
incentives
remuneration
de-prescribe
barrier
deprescribing.
There
significant
difference
across
professional
assertion
pressure
from
pharmaceutical
companies
(
=
0.037).
Conclusions
this
had
various
considerations
medication
life.
Having
every
involved
patient
not
necessarily
need
regulations
policies
support
identified
reduce
effective
process.
Language: Английский